Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with Extradenticle and Homothorax. by Jesús R Curt, Paloma Martín, David Foronda, Bruno Hudry, Ramakrishnan Kannan, Srividya Shetty, Samir Merabet, Andrew J Saurin, Yacine Graba, Ernesto Sánchez-Herrero

“…Hox protein functional specificity is reached, at least in part, through interactions with Pbc (Extradenticle (Exd) in Drosophila) and Meis/Prep (Homothorax (Hth) in Drosophila) proteins. …”
Get full text

Supervised machine learning reveals introgressed loci in the genomes of Drosophila simulans and D. sechellia. by Daniel R Schrider, Julien Ayroles, Daniel R Matute, Andrew D Kern

“…Here we describe a data set of outbred diploid Drosophila sechellia genomes, and combine them with data from D. simulans to examine recent introgression between these species using FILET. …”
Get full text

EFFECT OF ELEVATED TEMPERATURE ON THE SURVIVAL OF DROSOPHILA MELANOGASTER INFECTED WITH A PATHOGENIC WOLBACHIA STRAIN by A. A. Strunov, Yu. Yu. Ilinskii, I. K. Zakharov, E. V. Kiseleva

Subjects: “…drosophila melanogaster…”
Get full text

SURVIVAL CURVE ANALYSIS FOR DROSOPHILA MELANOGASTER WITH D-GADD45 OVEREXPRESSION IN THE NERVOUS SYSTEM by E. N. Plyusnina, M. V. Shaposhnikov, E. N. Andreeva, A. A. Moskalev, L. V. Omelyanchuk

Subjects: Get full text

The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling. by Alessia Soldano, Zeynep Okray, Pavlina Janovska, Kateřina Tmejová, Elodie Reynaud, Annelies Claeys, Jiekun Yan, Zeynep Kalender Atak, Bart De Strooper, Jean-Maurice Dura, Vítězslav Bryja, Bassem A Hassan

“…APP's in vivo function in the brain and the mechanisms underlying it remain unclear and controversial. Drosophila possesses a single APP homologue called APP Like, or APPL. …”
Get full text

Morphological and functional convergence of visual projection neurons from diverse neurogenic origins in Drosophila by Rana Naja El-Danaf, Katarina Kapuralin, Raghuvanshi Rajesh, Félix Simon, Nizar Drou, Filipe Pinto-Teixeira, Mehmet Neset Özel, Claude Desplan

“…Abstract The Drosophila visual system is a powerful model to study the development of neural circuits. …”
Get full text

CDK12 antagonizes a viral suppressor of RNAi to modulate antiviral RNAi in Drosophila by Liqin Zhang, Yu Liang, Jiayu Qin, Chen Liu, Mengwei Shang, Xiaoming Sun

“…Furthermore, the knockdown of CDK12 inhibited the production of vsiRNAs in FHV-infected Drosophila cells. This study revealed that CDK12 mediated a counter-counter-defense strategy against VSR, thereby enhancing antiviral RNAi immunity in Drosophila.IMPORTANCEThe arms race between virus and host immunity is never-ending. …”
Get full text

Identification of proteins that can participate in the recruitment of Ttk69 to genomic sites of Drosophila melanogaster by I. S. Osadchiy, T. N. Fedorova, P. G. Georgiev, O. G. Maksimenko

Subjects: “…drosophila…”
Get full text

Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus. by Daniel A Barbash, Philip Awadalla, Aaron M Tarone

“…Experimentally tractable models are required to identify and test candidate hybrid incompatibility genes. Several Drosophila melanogaster genes involved in hybrid incompatibility have been identified but none has yet been shown to have functionally diverged in accordance with the Dobzhansky-Muller model. …”
Get full text

Kank Is an EB1 interacting protein that localises to muscle-tendon attachment sites in Drosophila. by Sara M R Clohisey, Nikola S Dzhindzhev, Hiroyuki Ohkura

“…We report the identification of Kank, the sole Drosophila orthologue of human Kank proteins, as an EB1 interactor that predominantly localises to embryonic attachment sites between muscle and tendon cells. …”
Get full text

Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity by Sudershana Nair, Nicholas E Baker

Subjects: Get full text

Age- and oxidative stress-induced centrosome amplification and renal stones in Drosophila Malpighian tubules by Hyun-Jin Na, Mi-Jeong Sung, Joung-Sun Park

Subjects: “…drosophila…”
Get full text

A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration by Dan Jiang, Pengyue Li, Yi Lu, Jiaxin Tao, Xue Hao, Xiaodong Wang, Wei Wu, Jinjin Xu, Haoen Zhang, Xiaoyu Li, Yixing Chen, Yunyun Jin, Lei Zhang

“…Here, from an RNA interference (RNAi) screen in adult Drosophila intestinal stem cells (ISCs), we identify a factor, Pax, which is orthologous to mammalian PXN, coordinates the proliferation and differentiation of ISCs during both normal homeostasis and injury-induced midgut regeneration in Drosophila. …”
Get full text

Experimental adaptation to singular pathogen challenge reduces susceptibility to novel pathogens in Drosophila melanogaster by Aparajita Singh, Aabeer Basu, Biswajit Shit, Tejashwini Hegde, Nitin Bansal, Nagaraj Guru Prasad

“…Host adaptation to one pathogen can either increase its susceptibility to a novel pathogen, due to specialization of immune defenses and trade-offs between different arms of the immune system, or can decrease susceptibility to novel pathogens by virtue of cross-resistance. Using laboratory Drosophila melanogaster populations, we explore if hosts experimentally adapted to surviving infection challenges by a single bacterial pathogen are also better at surviving infection challenges by novel bacterial pathogens. …”
Get full text

Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM by Agalya Periasamy, Pamela Ornelas, Thomas Bausewein, Naomi Mitchell, Jiamin Zhao, Leonie M. Quinn, Werner Kuehlbrandt, Jacqueline M. Gulbis

Subjects: Get full text

Rare <i>Wolbachia</i> genotypes in laboratory <i>Drosophila melanogaster</i> strains by A. S. Ryabinin, O. D. Shishkina, Yu. Yu. Ilinsky, R. A. Bykov

Subjects: “…<i>drosophila melanogaster</i>…”
Get full text

Neural circuits underlying context-dependent competition between defensive actions in Drosophila larvae by Maxime Lehman, Chloé Barré, Md Amit Hasan, Benjamin Flament, Sandra Autran, Neena Dhiman, Peter Soba, Jean-Baptiste Masson, Tihana Jovanic

“…Using neuronal manipulations, machine learning-based behavioral detection, electron microscopy (EM) connectomics and calcium imaging in Drosophila larvae, we map second-order interneurons that are differentially involved in the competition between defensive actions in response to competing aversive cues. …”
Get full text

Characterisation of Drosophila UbxCPTI000601 and hthCPTI000378 Protein Trap Lines by Siew Woh Choo, Ching Yew Beh, Steven Russell, Robert White

“…In Drosophila, protein trap strategies provide powerful approaches for the generation of tagged proteins expressed under endogenous control. …”
Get full text

Drosophila Mutant Model of Parkinson’s Disease Revealed an Unexpected Olfactory Performance: Morphofunctional Evidences by Francescaelena De Rose, Valentina Corda, Paolo Solari, Patrizia Sacchetti, Antonio Belcari, Simone Poddighe, Sanjay Kasture, Paolo Solla, Francesco Marrosu, Anna Liscia

“…We sought to use the fruit fly Drosophila melanogaster as a model organism to explore olfactory function in LRRK loss-of-function mutants, which was previously demonstrated to be a useful model for PD. …”
Get full text

Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense by Fanrui Kong, Zixuan Wang, Chuchu Zhang, Yihua Xiao, Muhammad Abdul Rehman Saeed, Weini Li, Akira Goto, Qingshuang Cai, Shanming Ji

Subjects: Get full text