Moesin integrates cortical and lamellar actin networks during Drosophila macrophage migration by Besaiz J. Sánchez-Sánchez, Stefania Marcotti, David Salvador-Garcia, María-del-Carmen Díaz-de-la-Loza, Mubarik Burki, Andrew J. Davidson, Will Wood, Brian M. Stramer

“…These modes are assumed to be driven by mutually exclusive actin cytoskeletal organizations, which are either lamellar (flat, branched network) or cortical (crosslinked to the plasma membrane). Here we exploit Drosophila macrophage (hemocyte) developmental dispersal to reveal that these cells maintain both a lamellar actin network at their cell front and a cortical actin network at the rear. …”
Get full text

Steroid hormone-induced wingless ligands tune female intestinal size in Drosophila by Lisa Zipper, Bernat Corominas-Murtra, Tobias Reiff

“…Mating increases production of the steroid hormone Ecdysone released by the Drosophila ovaries that stimulates intestinal stem cell (ISC) divisions. …”
Get full text

The RNA-binding protein Modulo promotes neural stem cell maintenance in Drosophila. by Amalia S Parra, Christopher A Johnston

“…A small population of stem cells in the developing Drosophila central nervous system generates the large number of different cell types that make up the adult brain. …”
Get full text

Low molecular weight chitosan attenuates acrylamide-induced toxicity in Drosophila melanogaster by Swetha Senthil Kumar, Sahabudeen Sheik Mohideen

“…This study evaluates the protective role of low and medium molecular-weight (MW) chitosan against ACR-induced toxicity using Drosophila melanogaster. Chitosan, a natural polysaccharide with antioxidant and prebiotic properties, was supplemented alongside ACR exposure in larvae and adult flies. …”
Get full text

Blobby is a synaptic active zone assembly protein required for memory in Drosophila by J. Lützkendorf, T. Matkovic-Rachid, S. Liu, T. Götz, L. Gao, O. Turrel, M. Maglione, M. Grieger, S. Putignano, N. Ramesh, T. Ghelani, A. Neumann, N. Gimber, J. Schmoranzer, A. Stawrakakis, B. Brence, D. Baum, Kai Ludwig, M. Heine, T. Mielke, F. Liu, A. M. Walter, M. C. Wahl, S. J. Sigrist

“…We here identify an additional Drosophila AZ protein, “Blobby”, essential for proper AZ nano-organization. …”
Get full text

Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species by Montserrat Torres-Oliva, Elisa Buchberger, Alexandra D. Buffry, Maike Kittelmann, Genoveva Guerrero, Lauren Sumner-Rooney, Pedro Gaspar, Georg C. Bullinger, Javier Figueras Jimenez, Fernando Casares, Saad Arif, Nico Posnien, Maria D. S. Nunes, Alistair P. McGregor, Isabel Almudi

Subjects: Get full text

Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing by Su Ee Tan, David Strutt

“…Mechanical forces exerted during tissue morphogenesis are emerging as crucial tissue-level directional cues, yet the mechanisms by which they regulate planar polarity are poorly understood. Using the Drosophila pupal wing, we confirm that tissue stress promotes proximal-distal (PD) planar polarity alignment. …”
Get full text

Drosophila Models of Parkinson's Disease: Discovering Relevant Pathways and Novel Therapeutic Strategies by Verónica Muñoz-Soriano, Nuria Paricio

“…These studies have been mainly performed in PD models created in mice, fruit flies, and worms. Among them, Drosophila has emerged as a very valuable model organism in the study of either toxin-induced or genetically linked PD. …”
Get full text

Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster by Yi Pan, Ke Fan, Linhao Zong, Yantao Luo, Xin Ni, Dong Chen, Jinjun Qian, Fei Ma, Jie Cheng, Miao Guan

Subjects: Get full text

Stage-specific modulation of Drosophila gene expression with muscle GAL4 promoters by Ziwei Zhao, Erika R Geisbrecht

Subjects: Get full text

Dissecting the sterility phenotype in gene edited Drosophila suzukii pgSIT males by Avery D. Witherbee, Stephanie Gamez

“…Abstract Drosophila suzukii is an invasive pest that affects many fresh, soft-skinned fruits such as strawberries and blueberries. …”
Get full text

Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes. by Sarah J Radford, Tranchau L Hoang, A Agata Głuszek, Hiroyuki Ohkura, Kim S McKim

“…We have examined oocytes lacking two kinetochore proteins, NDC80 and SPC105R, and a centromere-associated motor protein, CENP-E, to characterize the impact of kinetochore-microtubule attachments on spindle assembly and chromosome segregation in Drosophila oocytes. We found that the initiation of spindle assembly results from chromosome-microtubule interactions that are kinetochore-independent. …”
Get full text

Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster by Bert I. Crawford, Mary Jo Talley, Joshua Russman, James Riddle, Sabrina Torres, Troy Williams, Michelle S. Longworth

“…Here, we show that condensin subunit knockdown in NSPCs of the Drosophila larval central brain increases RTE expression and mobility which causes cell death, and significantly decreases adult head sizes and brain volumes. …”
Get full text

Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. by Shuang Li, Yongbin Chen, Qing Shi, Tao Yue, Bing Wang, Jin Jiang

“…Hedgehog transduces signal by promoting cell surface expression of the seven-transmembrane protein Smoothened (Smo) in Drosophila, but the underlying mechanism remains unknown. …”
Get full text

Rule-Based Knowledge Acquisition Method for Promoter Prediction in Human and Drosophila Species by Wen-Lin Huang, Chun-Wei Tung, Chyn Liaw, Hui-Ling Huang, Shinn-Ying Ho

“…PromHD identifies two feature subsets with 99 and 74 DNASDs and yields test accuracies of 96.4% and 97.5% in human and Drosophila species, respectively. Based on the 99- and 74-dimensional feature vectors, PromHD generates several if-then rules by using the decision tree mechanism for promoter prediction. …”
Get full text

Divergent effects of entomopathogenic fungi and medicinal mushroom species on Drosophila melanogaster lifespan by Md M. H. Nafis, Amran A. Q. A. Al-Shaarani, Mohammed H. M. Muafa, Yiwen Wang, Chunying Deng, Yusufjon Gafforov, Lorenzo Pecoraro

Subjects: Get full text

A split-GAL4 driver line resource for Drosophila neuron types by Geoffrey W Meissner, Allison Vannan, Jennifer Jeter, Kari Close, Gina M DePasquale, Zachary Dorman, Kaitlyn Forster, Jaye Anne Beringer, Theresa Gibney, Joanna H Hausenfluck, Yisheng He, Kristin Henderson, Lauren Johnson, Rebecca M Johnston, Gudrun Ihrke, Nirmala A Iyer, Rachel Lazarus, Kelley Lee, Hsing-Hsi Li, Hua-Peng Liaw, Brian Melton, Scott Miller, Reeham Motaher, Alexandra Novak, Omotara Ogundeyi, Alyson Petruncio, Jacquelyn Price, Sophia Protopapas, Susana Tae, Jennifer Taylor, Rebecca Vorimo, Brianna Yarbrough, Kevin Xiankun Zeng, Christopher T Zugates, Heather Dionne, Claire Angstadt, Kelly Ashley, Amanda Cavallaro, Tam Dang, Guillermo A Gonzalez III, Karen L Hibbard, Cuizhen Huang, Jui-Chun Kao, Todd Laverty, Monti Mercer, Brenda Perez, Scarlett Rose Pitts, Danielle Ruiz, Viruthika Vallanadu, Grace Zhiyu Zheng, Cristian Goina, Hideo Otsuna, Konrad Rokicki, Robert R Svirskas, Han SJ Cheong, Michael-John Dolan, Erica Ehrhardt, Kai Feng, Basel EI Galfi, Jens Goldammer, Stephen J Huston, Nan Hu, Masayoshi Ito, Claire McKellar, Ryo Minegishi, Shigehiro Namiki, Aljoscha Nern, Catherine E Schretter, Gabriella R Sterne, Lalanti Venkatasubramanian, Kaiyu Wang, Tanya Wolff, Ming Wu, Reed George, Oz Malkesman, Yoshinori Aso, Gwyneth M Card, Barry J Dickson, Wyatt Korff, Kei Ito, James W Truman, Marta Zlatic, Gerald M Rubin, FlyLight Project Team

“…Split-GAL4 driver lines allow specific targeting of cell types in Drosophila melanogaster and other species. We describe here a collection of 3060 lines targeting a range of cell types in the adult Drosophila CNS and 1373 lines characterized in third-instar larvae. …”
Get full text

Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster by Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah, Kemuma Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange

“…The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. …”
Get full text

Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster by Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah Kemuma, Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange

“…The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. …”
Get full text

Efficient k-mer based curation of raw sequence data: application in Drosophila suzukii by Gautier, Mathieu

“…We applied it to high-throughput whole-genome raw sequence data for 236 Ind-Seq and 22 Pool-Seq samples of the invasive species Drosophila suzukii. We first used Clark software to build a dictionary of species-discriminating k–mers from the curated assemblies of 29 target drosophilid species (including D. melanogaster, D. simulans, D. subpulchrella, or D. biarmipes) and 12 common drosophila pathogens and commensals (including Wolbachia). …”
Get full text