Antioxidant and anti-diabetic potential of the green synthesized silver nanoparticles using Martynia annua L. root extract by Megha B. Abbigeri, Bothe Thokchom, Sapam Riches Singh, Santosh Mallikarjun Bhavi, B.P. Harini, Ramesh Babu Yarajarla

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qDATA - an R application implementing a practical framework for analyzing quantitative real-time PCR data by Adrian Ionascu, Alexandru Al. Ecovoiu, Mariana Carmen Chifiriuc, Attila Cristian Ratiu

“…The efficiency of our computing approach was tested using input Ct values corresponding to immune related gene expression evaluated in experimental infection of Drosophila melanogaster and Apis mellifera workers. …”
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Syzygium malaccense leaf extract-mediated silver nanoparticles: synthesis, characterization, and biomedical evaluation in Caenorhabditis elegans and lung cancer cell line by Santosh Mallikarjun Bhavi, Bothe Thokchom, Sapam Riches Singh, Sukesh Kumar Bajire, Rajesh P. Shastry, B. S. Srinath, Shivanand S. Bhat, Kotresha Dupadahalli, Chandramohan Govindasamy, Swati Ravi Chalekar, B. P. Harini, Ramesh Babu Yarajarla

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Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. by Ashish Kumar Maurya, Jin Ben, Zhonghua Zhao, Raymond Teck Ho Lee, Weixin Niah, Ashley Shu Mei Ng, Audrey Iyu, Weimiao Yu, Stone Elworthy, Fredericus J M van Eeden, Philip William Ingham

“…Loss of function mutations of Kif7, the vertebrate orthologue of the Drosophila Hh pathway component Costal2, cause defects in the limbs and neural tubes of mice, attributable to ectopic expression of Hh target genes. …”
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Diet modification and metformin have a beneficial effect in a fly model of obesity and mucormycosis. by Fazal Shirazi, Dimitrios Farmakiotis, Yuanqing Yan, Nathaniel Albert, Kim-Anh Do, Dimitrios P Kontoyiannis

“…In an experimental model of obesity and hyperglycemia in Drosophila melanogaster we studied the effect of diet modification and administration of metformin on systemic infection with Rhizopus, a common cause of mucormycosis in diabetic patients. …”
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The role of SAGA in the transcription and export of mRNA by E. N. Nabirochkina, M. M. Kurshakova, S. G. Georgieva, D. V. Kopytova

“…We studied the DUBm of SAGA in Drosophila melanogaster and identified Drosophila homologs of yeast DUBm components. …”
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Coupling Planar Cell Polarity Signaling to Morphogenesis by Jeffrey D. Axelrod, Helen McNeill

“…We then discuss how the vertebrate processes of convergent extension and cochlear hair-cell development may relate to Drosophila PCP signaling.…”
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Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential by Ines Hadrich, Mariem Turki, Mariem Turki, Imen Chaari, Imen Chaari, Balkiss Abdelmoula, Rahma Gargouri, Nahed Khemakhem, Dhawia Elatoui, Fatma Abid, Sonda Kammoun, Sonda Kammoun, Mona Rekik, Mona Rekik, Samir Aloulou, Samir Aloulou, Mariem Sehli, Mariem Sehli, Aymen Ben Mrad, Aymen Ben Mrad, Sourour Neji, Fabian M. Feiguin, Jihene Aloulou, Jihene Aloulou, Nouha Bouayed Abdelmoula, Hayet Sellami, Hayet Sellami

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Coleopteran Antimicrobial Peptides: Prospects for Clinical Applications by Monde Ntwasa, Akira Goto, Shoichiro Kurata

“…Although coleopterans comprise the largest and most diverse order of eukaryotes and occupy an earlier branch than Drosophila in the holometabolous lineage of insects, their immune system has not been studied extensively. …”
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Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless. by Weronika Fic, François Juge, Johann Soret, Jamal Tazi

“…The genetic programs specifying eye development are highly conserved during evolution and involve the vertebrate Pax-6 gene and its Drosophila melanogaster homolog eyeless (ey). Here we report that the SR protein B52/SRp55 controls a novel developmentally regulated splicing event of eyeless that is crucial for eye growth and specification in Drosophila. …”
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Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. by Wilhelm Palm, Marta M Swierczynska, Veena Kumari, Monika Ehrhart-Bornstein, Stefan R Bornstein, Suzanne Eaton

“…Multiple mechanisms have been proposed to release Hh proteins in distinct forms; in Drosophila, lipoproteins facilitate long-range Hh mobilization but also contain lipids that repress the pathway. …”
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A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway by Pengdi Yang, Meiling Fan, Ying Chen, Dan Yang, Lu Zhai, Baoyu Fu, Lili Zhang, Yanping Wang, Rui Ma, Liwei Sun

“…The protective effects of ginsenoside Rg1 were analyzed in a Drosophila model of oxidative damage induced by tert-butyl hydroperoxide. …”
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Muscular TOR knockdown and endurance exercise ameliorate high salt and age-related skeletal muscle degradation by activating the MTOR-mediated pathway. by Shi-Jie Wang, Deng-Tai Wen, Ying-Hui Gao, Jing-Feng Wang, Xing-Feng Ma

“…In this study, muscular TOR gene overexpression and RNAi were constructed by constructing MhcGAL4/TOR-overexpression and MhcGAL4/TORUAS-RNAi systems in Drosophila. The results showed that muscle TOR knockdown and endurance exercise significantly increased the climbing speed, climbing endurance, the expression of autophagy related gene 2(ATG2), silent information regulator 2(SIR2), and pparγ coactivator 1(PGC-1α) genes, and superoxide dismutases(SOD) activity, but it decreased the expression of the TOR gene and reactive oxygen species(ROS) level, and it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet. …”
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In Silico Evolution of Gene Cooption in Pattern-Forming Gene Networks by Alexander V. Spirov, Marat A. Sabirov, David M. Holloway

“…We use a data-driven model of insect segmentation, for the fruit fly Drosophila, and evaluate fitness by robustness to maternal variability—a major constraint in biological development. …”
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Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons by Reut Hilu-Dadia, Aseel Ghanem, Shelly Vogelesang, Malak Ayoub, Ketty Hakim-Mishnaevski, Estee Kurant

“…Summary: The elimination of superfluous neurons via apoptosis and subsequent glial phagocytosis is crucial for the development of the central nervous system (CNS). In Drosophila, two glial phagocytic receptors, six-microns-under (SIMU) and Draper, mediate the phagocytosis of apoptotic neurons during embryogenesis. …”
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Coupling of mitochondrial state with active zone plasticity in early brain aging by Lu Fei, Yongtian Liang, Ulrich Kintscher, Stephan J. Sigrist

“…Changes in presynaptic active zone proteins (''PreScale'') are considered a dynamic, resilience-enhancing form of plasticity in the process of early, still reversible aging of the Drosophila brain. Aging, however, triggers significant changes not only of synapses but also mitochondria. …”
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Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo by Alison G Cole, Tamar Hashimshony, Zhuo Du, Itai Yanai

“…Moreover, we find that genes that segment the entire embryo in Drosophila have orthologs in C. elegans that exhibit sub-lineage-specific expression. …”
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Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol by Guohua Yin, Geromy G. Moore, Joan Wennstrom Bennett

“…When Drosophila was cultivated in an atmosphere shared with VOC mixtures released from growing cultures of several medically important fungi, including Aspergillus fumigatus, toxicity was observed. …”
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Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model by Huynh Man Anh, Dao My Linh, Vuu My Dung, Dang Thi Phuong Thao

“…With the purpose of further investigating the efficiency of vitamin C in PD treatment, we used dUCH knockdown Drosophila model to examine the dose- and time-dependent effects of vitamin C on PD-like phenotypes. …”
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Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin by Zongzhong Liu, Yanfei He, Yuhan Wang, Kefeng Ren, Pengpeng Xia, Binbin Xie, Tian Wei

“…Here, we employed the adult intestine of Drosophila melanogaster, a notable invertebrate model organism, to investigate the intestinal toxicity of 3-MCPD and its underlying mechanisms. …”
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