Identification of novel clinical subtypes in patients with microscopic polyangiitis using cluster analysis: multicenter REVEAL cohort study by Ayana Okazaki, Shogo Matsuda, Takuya Kotani, Keisuke Fukui, Keisuke Fukui, Takaho Gon, Ryu Watanabe, Atsushi Manabe, Mikihito Shoji, Keiichiro Kadoba, Ryosuke Hiwa, Wataru Yamamoto, Motomu Hashimoto, Tohru Takeuchi

“…Four distinct clinical subgroups were identified: Cluster 1 included the renal involvements and diffuse alveolar hemorrhage (DAH)-dominant group (N=33). Cluster 2 comprised the elderly onset systemic inflammation group (N=75). …”
Get full text

Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice by Alexandra F. Putka, Varshasnata Mohanty, Stephanie M. Cologna, Hayley S. McLoughlin

“…Spinocerebellar ataxia type 3 (SCA3) is the most common dominantly inherited ataxia and belongs to the family of nine diseases caused by a polyglutamine expansion in the disease-causing protein. …”
Get full text

Dynamic Detection of Monocyte Subsets in Peripheral Blood of Patients with Acute Hypertriglyceridemic Pancreatitis by Junyuan Zheng, Junjie Fan, Chunlan Huang, Yingying Lu, Zehua Huang, Xingpeng Wang, Yue Zeng

“…Peripheral blood M1 and M2 monocytes showed different dynamic changes in mild and severe HTGP. A more dominant role of CD14+CD86+ M1 monocytes may be involved in the pathogenesis of HTGP.…”
Get full text

The Origin of the Matter Matters: The Influence of Terrestrial Inputs on Coastal Benthic Microeukaryote Communities Revealed by eDNA by Mathisse Meyneng, Raffaele Siano, Naïna Mouras, Dominique Ansquer, Christine Laporte‐Magoni, Florence Antypas, Thomas Haize, Hugues Lemonnier

“…Particularly, the influence of ultramafic soils was highlighted by higher nickel concentration (correlated to Co, Cr, Mn, and Fe). Diatoms were the dominant taxonomic group, especially the classes of Bacillariophyceae and Mediophyceae. …”
Get full text

Three-dimensional reconstruction and connectivity analysis of REV-size organic matter in shales by Dongchen Liu, Dongchen Liu, Dongchen Liu, Xuefeng Yang, Xuefeng Yang, Shengxian Zhao, Shengxian Zhao, Deliang Zhang, Deliang Zhang, Shan Huang, Shan Huang, Ning Zhu, Ning Zhu, Jianqi Rong, Bowen Shi, Zhiwei Wang, Chao-Zhong Qin

“…Type A and Type B OM have poor connectivity, while Type C OM holds the best connectivity dominating gas transport at the REV scale. Moreover, the reconstructed 3D digital rocks of OM can be used in the numerical modeling of REV-size gas transport in shales.…”
Get full text

A rare splice site mutation in the gene encoding glucokinase/hexokinase 4 in a patient with MODY type 2 by D. E. Ivanoshchuk, E. V. Shakhtshneider, A. K. Ovsyannikova, S. V. Mikhailova, O. D. Rymar, V. I. Oblaukhova, A. A. Yurchenko, M. I. Voevoda

“…Maturity onset diabetes of the young (MODY) is a hereditary form of diabetes with an autosomal dominant type of inheritance, an onset at a young age, and a primary defect in pancreatic β-cell function. …”
Get full text

Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia by Jiawei Zhou, Zhifen He, Yidong Wu, Yiya Chen, Xiaoxin Chen, Yunjie Liang, Yu Mao, Zhimo Yao, Fan Lu, Jia Qu, Robert F. Hess

“…Based on more recent research concerning adult ocular dominance plasticity, we conclude that inverse occlusion in adults and old children with amblyopia does produce long-term gains to binocular balance and that acuity and stereopsis can improve in some subjects.…”
Get full text

Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

“…Across all three plant species, Proteobacteria emerged as the dominant bacterial groups in all root components. The abundance and diversity of bacterial communities exhibited a decline from the rhizosphere to the endosphere, accompanied by an increase in the number of distinctive biomarkers from the rhizosphere to the endosphere. …”
Get full text

Spatiotemporal dynamics of carbon sequestration capacity and its determinants in rubber plantation ecosystems of Hainan Island by Yinghe An, Zhixiang Wu, Runqing Zhang, Xiang Zhang, Zhenghong Tan, Zhongyi Sun

“…Among the climatic factors, changes in water conditions exert a dominant influence on NEP variations (−66.03 %); however, different categories of water conditions (precipitation and relative humidity) have opposite effects (negative effects of precipitation and positive effects of atmospheric relative humidity). …”
Get full text

Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing by Maham Tanveer, Karina Klein, Brigitte von Rechenberg, Salim Darwiche, Hannah L. Dailey

“…Conclusion: Ovine osteotomies can heal with high gap strains (> 10%) dominated by shear conditions. High gap strain appears to be a transient local limiter of osteogenesis, not a global inhibitor of secondary fracture repair. …”
Get full text

Genomic insights into population dynamics and adaptive strategies of the endangered dipterocarp, Hopea chinensis by Wei-Min Xiang, Yu-Ting Jiang, Jie Zou, Yan Deng, Kai Jiang, Kai-Jian Zhang, Xin-Yu Zhou, Kai-Xi Quan, Zi-Wen Han, Wei-Chao Liu, Liang Tang, Yuan-Yuan Li, Simon T. Segar, Yuan-Ye Zhang, Xing-Hua Hu, Rong Wang, Xiao-Yong Chen

“…Asian rainforests are a biodiversity hotspot and are dominated by dipterocarps. Thus, protecting endangered dipterocarp species living on the distribution boundary of dipterocarps is a central factor in maintaining the range of Asian rainforests. …”
Get full text

Formation Pathways and Emission Characteristics of PCDD/Fs during Co-combustion Tests of Sewage Sludge in Coal-fired Power Plants by Xiangbo Zou, Ji Ye, Chuangting Chen, Hui Huang, Wenxin Yu, Yuxuan Ying, Tieying Mao, Yunfeng Ma, Bingjian Zhu, Xiaoqing Lin

“…In comparison, the increased co-combustion ratio of SS decreased the 2,3,7,8-PCDD/F concentrations from 0.0222 to 0.0197–0.0098 ng g−1 and caused the change of dominant component from PCDDs (72.8%) to PCDFs (57.4%–59.5%) due to the inhibition effect of S-based substances. …”
Get full text

H-AMR FORGE’d in FIRE. I. Magnetic State Transitions, Jet Launching, and Radiative Emission in Super-Eddington, Highly Magnetized Quasar Disks Formed from Cosmological Initial Cond... by Nicholas Kaaz, Matthew Liska, Alexander Tchekhovskoy, Philip F. Hopkins, Jonatan Jacquemin-Ide

“…Despite the toroidal magnetic field's dominance at large radii, vertical magnetic flux builds up near the event horizon, leading to a magnetic state transition within the inner 200 gravitational radii of the disk. …”
Get full text

Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria by Filippo Fratini, Chiara Pecorini, Ilaria Resci, Emma Copelotti, Francesca Paola Nocera, Basma Najar, Simone Mancini

“…In an era dominated by the phenomenon of antibiotic resistance, it is increasingly important to look for alternatives to synthetic antibiotics. …”
Get full text

Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide by Martin Javorský, Eva Babjaková, Lucia Klimčáková, Zbynek Schroner, Jozef Židzik, Mária Štolfová, Ján Šalagovič, Ivan Tkáč

“…TCF7L2 rs7903146 C/T genotype was identified by real-time PCR with subsequent melting curve analysis. Analyses using the dominant genetic model showed significantly higher effect of gliclazide in the CC genotype group in comparison with combined CT + TT genotype group (1.32±0.15% versus 0.73±0.11%, Padj=0.005). …”
Get full text

Advanced perspective on heavily phosphorus-doped diamond layers via optical emission spectroscopy by Kil-dong Sung, Stefan Andrei Irimiciuc, Michal Novotný, Zdeněk Weiss, Pavel Hubík, Jaromír Kopeček, Martin Vondráček, Vincent Mortet

“…By understanding plasma properties and their effects on [P], heavily PDD has been effectively achieved with enhancing [P] (up to 745%) and η (up to 143%) by alternating the dominant radical species in the plasma. Time-dependent control of precursor gas flow allowed modulation of IPH/ICH, improving control over phosphorus incorporation. …”
Get full text

The line Rico is the earliest maturing accession in the VIR collection of spring bread wheat by B. V. Rigin, E. V. Zuev, A. S. Andreeva, Z. S. Pyzhenkova, I. I. Matvienko

“…The absence of response to vernalization in Rico, Fori and Rifor lines was determined by the dominant alleles Vrn-A1, Vrn-B1 and Vrn-D1. Photoperiodism in Rico and partially in Rifor was controlled by at least two genes: Ppd-D1 and Ppd-B1. …”
Get full text

Using Synchrotron Radiation X-ray Fluorescence (SRXRF) to Assess the Impacts of Shipping Emissions on the Variations of PM10-bound Elemental Species by Siwatt Pongpiachan, Nichada Jearanaikoon, Kanjana Thumanu, Jureerat Pradubsri, Ratchadaporn Supruangnet, Chaisri Tharasawatpipat, Muhammad Zaffar Hashmi, Ronbanchob Apiratikul

“…By applying the concept of enrichment factor (EF), Se is exceedingly enriched in all observatory sites indicating that industrial emissions were the dominant contributor of Se at the ambient air of Lam Chabang. …”
Get full text

Enhancing detection of STEC in the meat industry: insights into virulence of priority STEC by Mai-Lan Tran, Sabine Delannoy, Patrick Fach

“…Among the stx2-positive samples, stx2a and/or stx2d subtypes dominate. Introduction of espK, espV markers on 868 stx+/eae+ beef enrichment broths reduced the number of presumptive positive results by 31%, compared to the ISO/TS 13136:2012 reference method. …”
Get full text

Exploration on Formation Mechanism of Core Discing Based on Energy Analysis by Siqi Ye, Jianan Li, Jing Xie, Bengao Yang, Haichun Hao, Fei Li

“…Research shows that in situ stress combination is the most dominant factor of core discing. When the hydrostatic stress increases from 40 MPa to 80 MPa, the maximum tensile stress at the core stub increases by 98.42%. …”
Get full text