Pirfenidone Accelerates Wound Healing in Chronic Diabetic Foot Ulcers: A Randomized, Double-Blind Controlled Trial by Luz E. Gasca-Lozano, Silvia Lucano-Landeros, Héctor Ruiz-Mercado, Adriana Salazar-Montes, Ana Sandoval-Rodríguez, Jesus Garcia-Bañuelos, Arturo Santos-Garcia, Judith R. Davila-Rodriguez, José Navarro-Partida, Hiram Bojórquez-Sepúlveda, Juan Castañeda-Gomez, José Domínguez-Rosales, Myriam A. Ruiz-Arcos, María Guadalupe Sánchez-Parada, Juan Armendariz-Borunda

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N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis by Mariana O. Ribeiro, Mafalda Oliveira, Verónica Nogueira, Vítor Costa, Vitor Teixeira

“…Mutations in BSCL2, particularly N88S and S90L, lead to seipinopathies, which correspond to a cohort of motor neuron diseases (MNDs) characterized by the accumulation of misfolded N88S seipin into inclusion bodies (IBs) and cellular dysfunctions. …”
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It is time to tackle psychological determinants of obesity and eating disorders by Pietro Crescenzo

“…Obesity and overweight constitute an important source of morbidity, impaired quality of life and mortality, as they are associated with several cancers, diabetes and cardiovascular diseases [5]. The worldwide prevalence of obesity nearly doubled between 1980 and 2008. …”
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Effects of Lupeol on Intestinal Anastomosis After Experimental Intestinal Ischemia-Reperfusion Injury in Rats by Kaya C, Kapisiz A, Eryilmaz S, Karabulut R, Turkyilmaz Z, Inan MA, Aydin GY, Celik MA, Sonmez K

“…Cem Kaya,1 Alparslan Kapisiz,1 Sibel Eryilmaz,1 Ramazan Karabulut,1 Zafer Turkyilmaz,1 Mehmet Arda Inan,2 Gizem Yaz Aydin,3 Mert Alperen Celik,4 Kaan Sonmez1 1Department of Pediatric Surgery, Faculty of Medicine, Gazi University, Yenimahalle, Ankara, Turkey; 2Department of Pathology, Faculty of Medicine, Gazi University, Yenimahalle, Ankara, Turkey; 3Department of Biochemistry, Faculty of Medicine, Gazi University, Yenimahalle, Ankara, Turkey; 4Faculty of Medicine, Gazi University, Yenimahalle, Ankara, TurkeyCorrespondence: Cem Kaya, Medical Faculty, Gazi University, Department of Pediatric Surgery, Emniyet Mahallesi, Mevlana Bulvarı, No: 29, Yenimahalle, Ankara, 06500, Turkey, Tel +90 312 2026213, Fax +90 312 2230528, Email drcemkaya61@gmail.comBackground: Intestinal ischemia/reperfusion (I/R) injury can occur in a wide variety of diseases and surgeries. If necessary, the blood flow should be restored, including re-anastomosis by removing the intestines with impaired circulation. …”
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Characteristics of beta parapapillary atrophy in primary angle-closure suspect by Qing Zhang, Ye Zhang, Xiaohua Pan, Hui Feng, Shuning Li, Zhi Li, Meijuan Zhang, Caixia Li, Fei Xiang, Qianqian Ji

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CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues by Yibing Lv, Yidan Zheng, Shanshan Su, Junyi Xiao, Jie Yang, Lingyun Xiong, Yanyan Guo, Xiaoqi Zhou, Nengqiang Guo, Ping Lei

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miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms by Lukas Geisler, Katharina Detjen, Teresa Hellberg, Marlene Kohlhepp, Carsten Grötzinger, Jana Knorr, Ines Eichhorn, Raphael Mohr, Theresa Holtmann, Bertram Wiedenmann, Frank Tacke, Christoph Roderburg, Alexander Wree

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Effect of glaucoma and cataract on daily activities in patients with sarcopenic obesity by A.E. Kopylov, N.M. Agarkov, M.V. Alymova

“…</p> <p> <b>Conclusions: a</b>mong age-related eye diseases in elderly patients, cataract and SO significantly limit daily activities. …”
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Role of the Bronchoalveolar Lavage in Noncritically Ill Patients during the SARS-CoV-2 Epidemic by Olivier Taton, Emmanuelle Papleux, Benjamin Bondue, Christiane Knoop, Sébastien Van Laethem, Alain Bauler, Delphine Martiny, Isabel Montesinos, Marie-Luce Delforge, Kahina Elmaouhab, Dimitri Leduc

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Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd by Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Mohammed Mostafa Al Quadir, Mst Rubaiat Nazneen Akhand, Mohammad Mehedi Hasan Khan

“…The effects of abusing antibiotics not only increase pathogenic resistance but also cause various diseases and syndromes. Gut microbiota contains many beneficial roles for health, while antibiotics kill both pathogens and gut microbiota which is considered one of the major side effects of antibiotics. …”
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Associations between Life’s Essential 8 and liver function: a cross-sectional study by Qiaoli Liang, Menglong Zou, Ziming Peng

“…Liver function is a critical indicator of overall health, with impairments linked to numerous chronic diseases. While the LE8 score has been extensively studied in relation to cardiovascular outcomes, its association with liver function remains underexplored. …”
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A novel marker to determine arrhytmia risk in elite cyclists: T peak T end by Bulent Isık, Z. İsik Solak Gormus, Huseyin Aslan, Abdullah Iclı, Galip Bilen Kurklu, Ozgur Cıftcı, Turhan Togan

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Evolution of Spanish population well-being during the COVID-19 pandemic: Results from the COSMO-Spain study by Catarina Santos-Ribeiro, Carmen Rodríguez-Blázquez, Alba Ayala, María Romay-Barja, María Falcón, Maria João Forjaz

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Medical treatment for dry eye in patients with keratoconus after corneal cross-linking by I.A. Bubnova, G.B. Egorova, V.V. Averich, T.S. Mitichkina

“…&nbsp;Mitichkina</b><br> </p> <p> <b>Scientific Research Institute of Eye Diseases, Moscow, Russian Federation</b> </p> <p> <i><b>Aim</b>: to assess the changes in precorneal tear film in patients with keratoconus after corneal cross-linking (CXL).…”
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Relationship Between Sleep Time and Depressive Symptoms in Middle-Aged and Elderly Chinese: Mediating Role of Body Pain by Yang Z, Li B, Ma D, Lv Y, Qiu X, Zhang W, Wang J, Zhang Y, Xu C, Deng Y, Li J, Zhen X, Zhang J

“…Ziqing Yang,1,&ast; Bingsong Li,2,3,&ast; Dan Ma,1,4 Yitong Lv,1 Xinhui Qiu,5 Wenge Zhang,6 Jianye Wang,7 Yanlin Zhang,8 Chunming Xu,9 Yuxin Deng,9 Jinyang Li,10 Xuemei Zhen,2,3 Jun Zhang1 1Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, Shandong, People’s Republic of China; 2Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 3NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, Shandong, 250012, People’s Republic of China; 4Department of Orthodontics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 5The second Hospital of Shandong University, Jinan, Shandong, 250033, People’s Republic of China; 6School of Management, Shandong University, Jinan, Shandong, 250100, People’s Republic of China; 7Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 8School of Basic Medical Sciences, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 9Department of Pediatrics, Xinjiang Medical University, Urumqi, People’s Republic of China; 10Faculty of Nursing, Shihezi University, Shihezi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xuemei Zhen; Jun Zhang, Email zhenxuemei@sdu.edu.cn; zhangj@sdu.edu.cnObjective: Existing research has yet to adequately examine the correlation between sleep time, body pain, and depressive symptoms. …”
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The associations between single nucleotide polymorphisms and diabetic retinopathy risk: an umbrella review by Shaofen Huang, Yonghui Feng, Ying Sun, Jiazi Liu, Pu Wang, Jingrong Yu, Xin Su, Shasha Han, Shiqi Huang, Haokun Huang, Shiyun Chen, Ying Xu, Fangfang Zeng

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Disability and Migration Routes: An Explorative Analysis Among Refugees Hosted in Italy by Marco Tofani, Marco Tofani, Maurizio Marceca, Maurizio Marceca, Donatella Valente, Donatella Valente, Giovanni Galeoto, Giovanni Galeoto, Mohamed Ali Ben Zina, Imène Soumaya Salhi, Khadija Elmadmad, Khadija Elmadmad, Hind Tak Tak, Justine Gosling, Satish Mishra, Valentina Gazzaniga, Marco Cilione, Silvia Iorio

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Development and validation of a predictive model and tool for functional recovery in patients after postero-lateral interbody fusion by Shuai Zhou, Zhenbang Yang, Wei Zhang, Shihang Liu, Qian Xiao, Guangzhao Hou, Rui Chen, Nuoman Han, Jiao Guo, Miao Liang, Qi Zhang, Yingze Zhang, Hongzhi Lv

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The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models by Yalan Liu, Fengzhong Wang, Lin Li, Bei Fan, Zhiqiang Kong, Jianxin Tan, Minmin Li

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The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction by Na Yang, Xiaoyan Li, Bo Wu, Longhao Dai, Shaobin Yang, Qinning Zhang, Shaobin Jia

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