Establishment of the first marine mollusk cell line from scallop (Chlamys farreri) trochophore by Zhenkui Qin, Aichang Ji, Meng Yan, Danwen Liu, Xixi Li, Xiaoli Hu, Zhifeng Zhang

Get full text

Sensitivitas Bakteri Penyebab Sepsis Neonatorum terhadap Meropenem di Neonatal Intensive Care Unit dan Perinatologi RSUP DR M Djamil Padang Padang Tahun 2012 by Susan Insani Putri, Aziz Djamal, Rahmatini .

“…<br />Kata kunci: Sepsis neonatorum, bakteri penyebab, meropenem</p><p>Abstract<br />Sepsis neonatorum is one of the diseases that cause the highest number of deaths in neonatal period. …”
Get full text

Development and Validation of a Routine Electronic Health Record-Based Delirium Prediction Model for Surgical Patients Without Dementia: Retrospective Case-Control Study by Emma Holler, Christina Ludema, Zina Ben Miled, Molly Rosenberg, Corey Kalbaugh, Malaz Boustani, Sanjay Mohanty

“…POD was identified using Confusion Assessment Method records and delirium International Classification of Diseases (ICD) codes. Controls without delirium or nurse-documented confusion were matched to cases by age, sex, race, and year of admission. …”
Get full text

Assessment of risk factors for osteopenia development in premature babies by A. Yu. Tsymbal, Yu. V. Kotlova

“…The chances of ultra-low SOS by Z-score are 14.22 times higher (OR = 14.22; CI 95 % [3.29; 61.57]) in PB born at 32 weeks of gestation and earlier. Extragenital diseases, clinical signs of calcium deficiency in mothers, and women’s intake of calcium and vitamin D3 during pregnancy did not have a statistically significant difference (p > 0.05) in the studied PB and control group. …”
Get full text

A Proteomic Study Based on Home Quarantine Model Identifies NQO1 and Inflammation Pathways Involved in Adenoid Hypertrophy by Chen P, Hou S, Pang X, Li L, Wei W

“…Penghui Chen,1– 3,&ast; Shule Hou,1– 3,&ast; Xiuhong Pang,4 Lei Li,1– 3 Wei Wei1– 3 1Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 4Department of Otolaryngology-Head and Neck Surgery, the Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Wei Wei; Lei Li, Department of Otolaryngology-Head & Neck Surgery, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Yangpu District, Shanghai, 200082, People’s Republic of China, Tel +86-21-25078893, Fax +86-21-65152394, Email weiwei8319@xinhuamed.com.cn; xyyh2711@126.comBackground: Adenoid hypertrophy is a common disorder of childhood, and has an unclear pathogenesis. …”
Get full text

Prevalence and Associated Risk Factors of Soil-Transmitted Helminth Infections among Schoolchildren around Lake Tana, Northwest Ethiopia by Melsew Getaneh, Tamirat Hailegebriel, Abaineh Munshea, Endalkachew Nibret

“…Soil-transmitted helminths (STHs) are among the most common neglected tropical diseases widely distributed in tropical countries with poor socioeconomic development. …”
Get full text

Physical Inactivation of Monodon Baculovirus (Mbv), a Pathogenic Virus of Tiger Prawn (Penaeus Monodon Fab.) by M. Alifuddin

“…Key words :  Tiger prawn (Penaeus monodon Fab.), viral diseases, physical inactivation. ABSTRAK Suatu penelitian mengenai inaktifasi fisik terhadap Monodon baculovirus (MBV), suatu virus patogen yang menyerang udang windu (Penaeus monodon Fab.), telah dilaksanankan sejak bulan Juli 1994 sampai bulan Maret 1995.  …”
Get full text

Maintaining operability at a high personal cost – a mixed method study on maternal healthcare workers’ experiences during the COVID-19 pandemic by Magnus Akerstrom, Anna Wessberg, Emina Hadžibajramović, Sofie Graner, Ylva Carlsson, Ola Andersson, Maria Jonsson, Elin Naurin, Malin Veje, Verena Sengpiel, Karolina Linden

Get full text

Low L3 skeletal muscle index and endometrial cancer: a statistic pooling analysis by Na Aru, Congyu Yang, Yuntian Chen, Jiaming Liu

Get full text

Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda. by Mwesigwa, Alex, Golumbeanu, Monica, Jones, Sam, Cantoreggi, L. Sara, Musinguzi, Benson, Nankabirwa, I. Joaniter, Bikaitwoha, Everd Maniple, Kalyango, N. Joan, Karamagi, Charles, Plucinski, Mateusz, Nsobya, L. Samuel, Nsanzabana, Christian, Byakika-Kibwika, Pauline

Get full text

Factors Associated with Stunting in Children Under Five Years of Age: A Case of Buhara Sub County, Kabale District. by Namanya, Oliver

“…The study recommended that, Kabale District local government in conjunction with Buhara Sub County leadership should come up with ordinances and byelaws on how to improve community sanitation and hygiene practices especially improving toilet coverage, hand washing and proper disposal of the wastes to avoid stunting as they pose great risk to diarrheal diseases leading to mal-absorption food. Keywords Stunting Children, Under Five Years, Age, Buhara Sub-County, Kabale District.…”
Get full text

Assessment of Hand-Hygiene Practices Among Health Care Workers at Kisoro Hospital, Kisoro District. by Nsenga, Alex

“…Purpose of the study: The main purpose of the study was to assess the hand hygiene practices among health care workers at Kisoro hospital in Kisoro District in order to contribute to the control of poor hygiene related diseases. Specific objectives of the study were; to examine the level of knowledge of health workers on hand-hygiene practice, to determine the level of adherence to hand-hygiene practice among health workers and to identify key barriers m implementation of hand-hygiene practice among health workers at Kisoro hospital in Kisoro District. …”
Get full text

Pattern of antibiotic dispensing at pharmacies according to access, watch, reserve (AWaRe) classification: multicenter study after COVID-19 waves in different districts of Pakistan by Faiz Ullah Khan, Farman Ullah Khan, Aqsa Sajjad, Tawseef Ahmad, Tauqeer Hussain Mallhi, Sayyad Ali, Kamran Hidayat Ullah, Shahid Shah

“…Antibiotics were dispensed without a prescription for diarrheal diseases in over 50% of pharmacies, with Metronidazole (n = 23, 11%), Azithromycin (n = 16, 7.6%), and Rifaximin (n = 15, 7.1%) being the most often prescribed. …”
Get full text

Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome by Shi Tai, Xuping Li, Zhaowei Zhu, Liang Tang, Hui Yang, Liyao Fu, Xinqun Hu, Zhenfei Fang, Shenghua Zhou

“…Hyperuricemia is a risk factor for cardiovascular diseases, but the impact of hyperuricemia and sex-related disparities is not fully clear in elderly patients with acute coronary syndrome (ACS). …”
Get full text

Sequence-structure based prediction of pathogenicity for amino acid substitutions in proteins associated with primary immunodeficiencies by Ekaterina S. Porfireva, Anton D. Zadorozhny, Anastasia V. Rudik, Dmitry A. Filimonov, Alexey A. Lagunin, Alexey A. Lagunin

“…A key aspect of PID diagnosis is identifying specific amino acid substitutions in the proteins related with heritable diseases. In this study, we have developed classification sequence-structure-property relationships (SSPR) models for predicting the pathogenicity of amino acid substitutions (AAS) in 25 proteins associated with the most important and genetically studied PIDs and encoded genes: IL2RG, JAK3, RAG1, RAG2, ADA, DCLRE1C, CD40LG, WAS, ATM, STAT3, KMT2D, BTK, FOXP3, AIRE, FAS, ELANE, ITGB2, CYBB, G6PD, GATA2, STAT1, IFIH1, NLRP3, MEFV, and SERPING1.MethodsThe data on 4825 pathogenic and benign AASs in the selected proteins were extracted from ClinVar and gnomAD. …”
Get full text

Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

“…Our platform provides a unique method for producing biologics-based degraders that may be used to treat diseases through event-driven pharmacology, thereby addressing unmet medical needs.…”
Get full text

Community health system capacities and capabilities within an evolving community health policy framework: mixed methods study of stakeholders in central Uganda by Raymond Tweheyo, Diana Atwine, Richard Kabanda, Ronald Miria Ocaatre, Bounggui Kim, Simon Erisa Waiswa, Prichard Denzel Kavuma, Yeni Lee, Loretah Mutoni, Solyi Kim, Yein Park, Monica Okuga

“…The mean age of the community health workforce was high at 50.9 (SD 11.9); the majority reported adequate skills in service delivery except for community first aid, Kangaroo mother care and noncommunicable diseases. Households’ most received CHW services included home visits, treatment for sick under-five children and child immunisation.Conclusions The existing CHW system has governance and reporting strengths but could be enhanced through revitalization, enhanced coordination of stakeholders, providing appropriate training, work tools, supervision and engaging the community for accountability of results.…”
Get full text

Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes by Yizhen Bai, Dechao Tan, Qiaowen Deng, Lingchao Miao, Yuehan Wang, Yan Zhou, Yifan Yang, Shengpeng Wang, Chi Teng Vong, Wai San Cheang

“…It has been demonstrated to ameliorate inflammation and metabolic diseases, which are associated with endothelial dysfunction. …”
Get full text

Prevalence, Indications, and Community Perceptions of Caesarean Section Delivery in Ngora District, Eastern Uganda: Mixed Method Study by Isaac Waniala, Sandra Nakiseka, Winnie Nambi, Isaac Naminya, Margret Osuban Ajeni, Jacob Iramiot, Rebecca Nekaka, Julius Nteziyaremye

“…Although appreciated as lifesaving for young mothers, those with diseases and recurrent intrauterine fetal demise, others considered CS a curse, marriage-breaker, misfortune, money-maker and a sign of incompetent health workers, and being for the lazy women and the rich civil servants. …”
Get full text

Incidence of type 2 diabetes and metabolic syndrome by Occupation – 10-Year follow-up of the Gutenberg Health Study by Juliane Bauer, Janice Hegewald, Karin Rossnagel, Sylvia Jankowiak, Michaela Prigge, Julian Chalabi, Matthias Nübling, Alice Freiberg, Merle Riechmann-Wolf, Pavel Dietz, Philipp S. Wild, Thomas Koeck, Manfred E. Beutel, Norbert Pfeiffer, Karl J. Lackner, Thomas Münzel, Konstantin Strauch, Philipp Lurz, Oliver Tüscher, Julia Weinmann-Menke, Stavros Konstantinides, Andreas Seidler

“…Abstract Background In view of demographic change, rising retirement age, and a growing shortage of skilled workers, it is increasingly important to prevent widespread diseases such as type 2 diabetes or its risk factor metabolic syndrome. …”
Get full text