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A Microflow Chip Technique for Monitoring Platelets in Late Pregnancy: A Possible Risk Factor for Thrombosis
Published 2025-01-01“…However, microfluidic technology can simulate a more realistic in vivo shear rate environment, providing more effective clinical application data and a theoretical basis for the diagnosis and prevention of platelet dysfunction and thrombotic diseases during pregnancy.Keywords: microfluidic chip, late pregnancy, platelets, adhesion aggregation, thrombosis…”
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44064
The relationship of the carriership of allelic variations in rs2228145 (A > C) of the<i>IL6R</i> gene with the levels of <i>VCAM1</i> and <i>ICAM1</i> gene transcripts in patients...
Published 2020-03-01“…The levels of plasma interleukin 6 and its soluble receptors were found to be elevated in subjects with cardiovascular diseases, which points to amplification of the IL-6-mediated trans-signaling pathway in cells and the development of chronic inflammation. …”
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44065
Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study
Published 2025-01-01“…Abstract Background Obstructive sleep apnea (OSA) is linked to various health conditions, including cardiovascular diseases and metabolic disorders. Hyperuricemia and gout may be associated with OSA, but large-scale studies on this are limited. …”
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44066
Phytochemical Analysis, Antioxidant Potential and Antibacterial Activities of Different Anatomical Parts of Hypericum cordifolium Choisy
Published 2024-01-01“…The findings of this study support the traditional use of this plant in Nepal for the treatment of diseases associated with bacterial infections. The present study revealed that the underutilized anatomical parts of H. cordifolium could be the source of various bioactive phytochemicals like other Hypericum species.…”
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The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis
Published 2022-01-01“…Osteomyelitis (OM) is one of the most risky and challenging diseases. Emerging evidence indicates OM is a risk factor for increasing incidence of venous thromboembolism (VTE) development. …”
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Enteric-Coated Aspirin Induces Small Intestinal Injury via the Nrf2/Gpx4 Pathway: A Promising Model for Chronic Enteropathy
Published 2025-02-01“…Mingyu Zhang, Suhong Xia, Lina Feng, Xu Han, Yu Zhang, Yujie Huang, Yiran Liu, Kai Zhao, Jialun Guan, Dean Tian, Jiazhi Liao, Yan Yu Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, People’s Republic of ChinaCorrespondence: Jiazhi Liao, Email liaojiazhi@tjh.tjmu.edu.cn; Yan Yu, Email whtj20200720@163.comBackground: Aspirin is widely used to prevent and treat cardiovascular diseases. The most common side effect is gastrointestinal damage. …”
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Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex
Published 2025-01-01“…Functional interruption of this valve can tilt the seesaw balance of BM-MSC differentiation towards osteogenesis, highlighting the interplaying co-repressors, such as HDAC1, as promising therapeutic targets to combat diverse degenerative orthopedic diseases.…”
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Association between diabetes mellitus and total hip arthroplasty outcomes: an observational study using the US National Inpatient Sample
Published 2024-07-01“…Objectives To investigate the association of diabetes with postoperative outcomes in patients undergoing primary total hip arthroplasty (THA).Design Retrospective cohort study using data from the US National Inpatient Sample (NIS).Setting Study cohort was hospitalisations for primary THA in the USA, identified from the 2016–2020 NIS.Participants We identified 2 467 215 adults in the 2016–2020 NIS who underwent primary THA using International Classification of Diseases, 10th Revision codes. Primary THA hospitlizations were analysed as the overall group and also stratified by the underlying primary diagnosis for THA.Outcome measures Outcome measures of interest were the length of hospital stay>the median, total hospital charges>the median, inpatient mortality, non-routine discharge, need for blood transfusion, prosthetic fracture, prosthetic dislocation and postprocedural infection, including periprosthetic joint infection, deep surgical site infection and postprocedural sepsis.Results Among 2 467 215 patients who underwent primary THA, the mean age was 68.7 years, 58.3% were female, 85.7% were white, 61.7% had Medicare payer and 20.4% had a Deyo-Charlson index (adjusted to exclude diabetes mellitus) of 2 or higher. 416 850 (17%) patients had diabetes. …”
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Comparative assessment of antibacterial effect of two types of laser and their effect on morphology and mineral content of dentin
Published 2023-12-01“…Background/aim Scientists have proven that the main cause of endodontic diseases and failures is the existence of micro-organisms in the root canals and inside the dentinal tubules. …”
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Contribution of Open Access Databases to Intensive Care Medicine Research: Scoping Review
Published 2025-01-01“…Topics related to cardiovascular and infectious diseases were predominant, accounting for 333 (25.5%) and 324 (24.8%) articles, respectively. …”
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Atypical Mucin Expression Predicts Worse Overall Survival in Resectable Pancreatic Ductal Adenocarcinoma
Published 2022-01-01“…More and more evidences show that mucins are involved in the development of pancreatic diseases. However, the relationship between mucin expression and prognosis of PDAC patients has been controversial in the past decades; therefore, we aim to figure out the association of mucin expression with survival in PDAC patients who underwent radical resection. …”
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Evaluation of the effect of soil and irrigation water characteristics on the chemical composition and antimicrobial activity of Mentha spicata L. essential oil: A plant used in tra...
Published 2025-03-01“…Mentha spicata L. is one of the most important essential oil species of the lamiaceae family, which the people of Kashan use as a sedative, to treat flatulence, Intestinal and stomach diseases heartache are traditionally used. The present study was designed and carried out in order to evaluate and compare the composition, yield, and antimicrobial properties of the essential oil of this plant from 5 plain areas of Kashan (Lathor, Meshkat, Taher Abad, Issa Abad, and Fin) with different water and soil characteristics. …”
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Occurrence of Enteric Viruses in Surface Water and the Relationship with Changes in Season and Physical Water Quality Dynamics
Published 2020-01-01“…Enteric viruses can affect both human and animal’s health by causing diseases such as gastrointestinal and respiratory infections. …”
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