Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve... by Jay Patel, Priya Bhavsar, Harsh Shah, Sandul Yasobant, Deepak Saxena, Anish Sinha, Somen Saha, Yogesh Patel

“…A total of 593 reported TB patients were recruited with an adjusted unified distribution based on the type of cases, site of diseases, and service facility through a simple random sampling method. …”
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Development of monoclonal antibodies against P. gingivalis Mfa1 and their protective capacity in an experimental periodontitis model by Mingya Cao, Siyu Wang, Shengke Zhou, Min Yan, Yu Zou, Yuan Cui, Xinyu Lou, Yichang Gao, Ying Chen, Zijing Han, Yi Qian, Jingying Chen, Xia Li

“…These findings suggest that Mfa1 represents a promising therapeutic target, and the development of anti-Mfa1 mAbs holds a potential as essential diagnostic and adjunctive therapeutic tools for managing P. gingivalis-related diseases.…”
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Phytochemical Characterization and Biological Activity of Two <i>Anacardiaceae</i> Species from Guinea-Bissau by Quintino Malú, Maryam Malmir, Gonçalo Infante Caldeira, Sofia Encarnação, Katelene Lima, Luís Catarino, Beatriz Silva Lima, João Rocha, Olga Silva

“…The dried leaves of <i>Lannea velutina</i> A.Rich. and <i>Sorindeia juglandifolia</i> Planch. ex Oliv. are commonly used in traditional medicine throughout West Africa to treat inflammatory diseases. The aim of the present study was to evaluate the anti-inflammatory activity of the standardized hydroethanolic (70%) extracts of these plants and to investigate the underlying mechanisms, with a focus on their antioxidant properties. …”
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The research progress on effective connectivity in adolescent depression based on resting-state fMRI by Xuan Deng, Jiajing Cui, Jinyuan Zhao, Jinji Bai, Junfeng Li, Kefeng Li

“…However, effective connection can reflect the upper and lower relationship of brain region interaction, and provide help for us to explore the mechanism of neurological diseases. Existing studies focus on the analysis of a single brain network, but rarely explore the interaction between multiple key networks.DiscussionTo do so, we can address these issues by integrating multiple technologies. …”
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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

“…Despite the elimination of smallpox, orthopoxviruses continue to be a source of biological danger for humans, as cowpox and monkey pox viruses circulate in nature and the last virus can cause both sporadic cases of human diseases and outbreaks of smallpox-like infection. …”
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Jackknife versus Lithotomy Position for Hemorrhoidectomy Surgery: A Randomized Controlled Trial by Sina Ghasemi, Behzad Imani, Alireza Jafarkhani, Ashkan Karimi, Ali Yamini

“…Background and Objective: Hemorrhoids are known as one of the most common anorectal diseases and the most common cause of lower gastrointestinal bleeding. …”
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Successful Regulatory T Cell-Based Therapy Relies on Inhibition of T Cell Effector Function and Enrichment of FOXP3+ Cells in a Humanized Mouse Model of Skin Inflammation by S. Landman, V. L. de Oliveira, M. Peppelman, E. Fasse, E. van Rijssen, S. C. Bauland, P. van Erp, I. Joosten, H. J. P. M. Koenen

“…Recent clinical trials using regulatory T cells (Treg) support the therapeutic potential of Treg-based therapy in transplantation and autoinflammatory diseases. Despite these clinical successes, the effect of Treg on inflamed tissues, as well as their impact on immune effector function in vivo, is poorly understood. …”
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Knowledge and Attitudes Regarding Human Papillomavirus Vaccination Among Future Healthcare Workers in Serbia by Nemanja Maletin, Nikola Denda, Ana Ljubičić, Radmila Velicki, Aleksandra Patić, Zoran Golušin, Tihomir Dugandžija, Vladimir Petrović, Mioljub Ristić, Vladimir Vuković

“…Background/Objectives: Adequate knowledge and correct attitudes about the HPV vaccine influence awareness of the importance of preventing HPV-related diseases, which is particularly important for future healthcare professionals. …”
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A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection by Ping Li, Ping Li, Ziyi Jiang, Jingjing Shi, Haochuan Sha, Zihang Yu, Yan Zhao, Sanyang Han, Lan Ma, Lan Ma, Lan Ma

“…BackgroundEpstein–Barr virus (EBV) is a significant global public health concern because of its association with various malignancies and autoimmune diseases. Over 90% of the global population is chronically infected with EBV, impacting numerous cancer-related cases annually. …”
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Antidepressant- and Anxiolytic-like Effects in Mice of Alkaloids from Aerial Parts of <i>Argemone platyceras</i> Link & Otto by Mayra Beatriz Gómez-Patiño, Rosa Estrada-Reyes, Héctor Hugo Hernández-Mendoza, Ángela Suarez-Rojas, Daniel Arrieta-Baez

“…<b>Conclusions:</b> The easy and standardized AlkExt analyzed in pharmaceuticals assays in this study strongly suggest its therapeutic potential to treat the comorbidity of anxiety and depression disorders and support further investigations in people with these diseases.…”
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The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradati... by Quan Yuan, Mingwei Wang, Zhaoxiang Zhang, Ruofei Wang, Dechao Wang, Zichun Sang, Pu Zhao, Xiaoli Liu, Xiaoying Zhu, Gaofeng Liang, Hua Fan, Dongmei Wang

“…Melatonin has been indicated to confer neuroprotection against brain diseases via its potent anti-ferroptotic effects. Therefore, this study aims to explore whether melatonin can mitigate BDE-47-elicited cognitive impairment via suppressing ferroptosis, and further delineate the underlying mechanisms. …”
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NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue by Letícia Aparecida Lopes Morgado, Larissa Maria Zacarias Rodrigues, Daiane Cristina Floriano Silva, Bruno Durante da Silva, Maria Claudia Costa Irigoyen, Ana Paula Cremasco Takano

“…This has important implications for the development of therapeutic strategies aimed at mitigating age-related cardiovascular diseases.…”
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Myelitis associated with glial fibrillary acidic protein IgG: characterization and comparison with aquaporin-4 IgG and myelin oligodendrocyte glycoprotein IgG myelitis by Yinyin Xie, Wanwan Zhang, Aoya Han, Wenlin Sun, Xinru Zhou, Yi Xie, Yunqing Ma, Yajun Lian, Cui Wang, Nanchang Xie

“…Imaging findings more common in GFAP-IgG than in AQP4-IgG myelitis were longer diseased segments, central canal enhancement, and gadolinium-enhancing brain lesions. …”
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Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes by Wiktor Stopyra, Oleksiy Voytsekhivskyy, Andrzej Grzybowski

“…Exclusion criteria were as follows: intraoperative or postoperative complications, previous eye surgery or corneal diseases, postoperative BCVA less than 0.8, and corneal astigmatism greater than 2.0 D. …”
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Ethical issues in the development and implementation of nutrition-related public health policies and interventions: A scoping review. by Thierry Hurlimann, Juan Pablo Peña-Rosas, Abha Saxena, Gerardo Zamora, Béatrice Godard

“…<h4>Results</h4>The ethics of public health prevention or treatment of obesity and non-communicable diseases is the most explicitly and frequently discussed subject. …”
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Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series by Alison K. Cohen, Toni Wall Jaudon, Eric M. Schurman, Lisa Kava, Julia Moore Vogel, Julia Haas-Godsil, Daniel Lewis, Samantha Crausman, Kate Leslie, Siobhan Christine Bligh, Gillian Lizars, JD Davids, Saniya Sran, Michael Peluso, Lisa McCorkell

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Prevalence and associated factors of parental refusal rates for routine immunisation: a cross-sectional study in Peshawar, Khyber Pakhtunkhwa, Pakistan-2024 by Muhammad Hakim, Farhad Ali, Zala, Aslam Pervaiz, Saima Afaq, Zia ul Haq

“…Parents who refused were less inclined to believe that vaccines protect children from vaccine preventable diseases (77% vs. 98%, p < 0.001) and expressed higher rates of vaccine hesitancy (47% vs. 29%, p = 0.003). …”
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Oral health risks in adults who use electronic nicotine delivery systems and oral nicotine pouches: a critical review of the literature and qualitative synthesis of the available e... by Gerhard Scherer, Nikola Pluym, Max Scherer

“…Abstract Background Use of combustible cigarettes (CCs) and smokeless oral tobacco products are well documented risk factors for a variety of oral diseases. However, the potential oral health risks of using recently introduced (since about 2000) non-combustible tobacco/nicotine products (NCPs: electronic cigarettes (ECs), heated tobacco products (HTPs) and oral nicotine pouches (ONPs), remain poorly established. …”
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Protocol for genetic analysis of population-scale ultra-low-depth sequencing data by Jingyu Zeng, Linxuan Li, Ying Lin, Xianmei Lan, Xinyi Zhang, Yingying Wang, Mingzhi Liao, Xin Jin, Huanhuan Zhu

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Pharmacognostic Characterization of Panchatikta, an Ayurvedic Polyherbal Combination—Exploring the Role of Botanical and Phytochemical Techniques in the Standardization and Validat... by C. M. Harinarayanan, M. Deepak, S. P. Geetha, Arun Karnwal, Gaurav Kumar, Anupam Kumar, Tabarak Malik

“…As Panchatikta is prescribed for various life-threatening diseases including cancer, the standards developed here ensure the authenticity of the ingredients, which in turn ensures the quality of the prepared medicines.…”
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