Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging by Seul Ki Kim, Sang-Back Kim, Seul Bi Lee, Kang sub Kim, So-Ri Son, En Jin Choi, Byung Chul Park, Eunyoung Hong, You Ah Kim, Byoung Seok Moon, Sullim Lee

“…Antioxidants that reduce ROS production and inhibit inflammatory skin lesions are considered beneficial for the treatment of inflammatory skin diseases and prevention of skin aging. In this study, we evaluated the potential of Nypa fruticans (NF), which is known for its antioxidant properties, to mitigate tumor necrosis factor-alpha (TNF-α)- and interferon-gamma (IFN-γ)-induced damage in normal human epidermal keratinocytes. …”
Get full text

Prognostic implications of system inflammation response index in atrial fibrillation patients with type 2 diabetes mellitus by Yang Chen, Bin Zhou, Chaoquan Peng, Yong Liu, Weiyan Lai

“…Abstract Systemic inflammation plays a crucial role in the pathogenesis and prognosis of diabetes and cardiovascular diseases. System inflammation response index (SIRI), is an emerging biomarker designed to assess the extent of systemic inflammation. …”
Get full text

Global, regional and national burdens of bipolar disorders in adolescents and young adults: a trend analysis from 1990 to 2019 by Yifan Chen, Long Sun, Meiqi Wang, Yunxi Zhong, Xiaoying Su, Qixiu Li, Ziming Shao

“…Background Bipolar disorder is identified as a cause of severe damage to the physical, psychological and social functioning of adolescents and young adults.Aims The aim of this study is to ascertain the trends in the burden of bipolar disorder among individuals aged 10–24 years at global, regional and national levels from 1990 to 2019.Methods The data analysed in this study were from the Global Burden of Diseases 2019. The numbers, rates per 100 000 population, average annual percentage changes (AAPCs) of incidence, prevalence and years lived with disability (YLDs) of bipolar disorder are reported at the global, regional and national levels among individuals aged 10–24 years. …”
Get full text

Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children by Daniel Prieto-Alhambra, Andrew J Carr, Antony J Palmer, Talita Duarte-Salles, Jose Luis Poveda, Daniel Martinez-Laguna, Carlen Reyes, Jeroen de Bont, Alan Silman

“…Models were adjusted for age, sex, socioeconomic status and nationality.Participants Children seen at age 4 years at paediatric primary care clinics between 1 January 2006 and 31 December 2013 and followed up until 31 December 2016 or age 15 years.Outcome measures Incident back pain registered by paediatricians at primary care using the International Statistical Classification of Diseases and Health Related Problems, 10th Edition code M54.Results 466 997 children were followed for a median 5.0 years (IQR 5.1). …”
Get full text

Optimization extraction process of Shenghua Decoction and evaluation of its analgesic effects by Zhonghui Pu, Lijuan Chen, Huaidan Liu, Jingzhu Deng, Li Li, Liang Xiong, Liuying Li

“…Shenghua Decoction (SHD) is a very famous formula that has been used for treating postpartum diseases in China. However, there has been no study published, to date, reporting the preparation process and analgesic effects of SHD. …”
Get full text

The feasibility study of natural pigments as food colorants and seasonings pigments safety on dried tofu coloring by Wei-Sheng Lin, Pei Hua He, Chi-Fai Chau, Bo-Kang Liou, Shiming Li, Min-Hsiung Pan

“…In addition, researches showed that chemical soy sauce produces a trace of methylglyoxal (MGO) in the manufacturing process, which is related to diseases such as oxidative stress, diabetes, and cognitive deterioration. …”
Get full text

Quantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis by Matteo Antonio Sacco, Valerio Riccardo Aquila, Saverio Gualtieri, Roberto Raffaele, Maria Cristina Verrina, Lucia Tarda, Santo Gratteri, Isabella Aquila

“…Marker levels were quantified using immunofluorescence, with cases meticulously selected to exclude confounding factors such as chronic diseases, pulmonary thromboembolism, and drowning. …”
Get full text

How Much Do We Know about the Biopsychosocial Predictors of Glycaemic Control? Age and Clinical Factors Predict Glycaemic Control, but Psychological Factors Do Not by Mohammad Farris Iman Leong Bin Abdullah, Hatta Sidi, Arun Ravindran, Paula Junggar Gosse, Emily Samantha Kaunismaa, Roslyn Laurie Mainland, Norlaila Mustafa, Nurul Hazwani Hatta, Puteri Arnawati, Amelia Yasmin Zulkifli, Luke Sy-Cherng Woon

“…Diabetes mellitus is one of the most common noncommunicable diseases in Malaysia. It is associated with significant complications and a high cost of treatment, especially when glycaemic control is poor. …”
Get full text

Risk Factors Influencing Cognitive Function in Elderly Patients With Late‐Life Depression: A Scoping Review by Ping Jiang, Yunfeng Gao, Lin Wang, Xiaojun Shao, Lei Zhang, Gang Zhu, Li Duan

“…ABSTRACT Background In recent years, cognitive impairment has emerged as a pivotal symptom in elderly patients with depression, exerting a substantial impact on the course and prognosis of diseases. Moreover, it persists even following remission from depression during the rehabilitation period. …”
Get full text

Retrospective Analyses of Potential Risk Factors for Posterior Capsule Opacification after Cataract Surgery by Shuang Wu, Nianting Tong, Lin Pan, Xiaohui Jiang, Yanan Li, MeiLing Guo, Hehuan Li

“…Statistically significant associations with PCO were found for age at the time of surgery (χ2 = 78.504; p<0.001), diabetes (χ2 = 4.829; p=0.028), immune diseases (χ2 = 4.234; p=0.004), high myopia (χ2 = 5.753; p=0.016), lens nucleus hardness (χ2 = 11.046; p=0.026), surgery type (χ2 = 11.354; p=0.001), a history of vitrectomy (χ2 = 4.212; p=0.004), ocular inflammation (χ2 = 6.01; p=0.009), and the intraocular lens (IOL) type (χ2 = 8.696; p=0.003). …”
Get full text

Antimicrobial resistance in wild game mammals: a glimpse into the contamination of wild habitats in a systematic review and meta-analysis by Claire Julie Akwongo, Luca Borrelli, Kurt Houf, Alessandro Fioretti, Maria Francesca Peruzy, Nicoletta Murru

“…Despite this popularity, there is a concern over its safety as many species of wildlife are reservoirs of zoonotic diseases including those of bacterial origin, more so antibiotic-resistant bacteria. …”
Get full text

Combined effect of exercise and curcumin on inflammation-associated microRNAs and cytokines in old male rats: A promising approach against inflammaging by Zahra Shargh, Keyvan Asghari, Morteza Asghariehahari, Leila Chodari

“…Purpose: Inflammation serves as a key contributor to various diseases, necessitating the discovery of new treatment approaches to address its causative role. …”
Get full text

Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…This, in turn, opens new windows of therapeutic intervention in inflammatory and immunological diseases characterized by immune system dysfunction, in which eVim and CitVim play a key role.…”
Get full text

Unlocking the genetic potential of Ethiopian fenugreek (Trigonella foenum-graecum L.) genotypes for future breeding by Zebib Berhe, Tesfaye Awas, Asmare Dejen, Metadel Adane, Baye Akele, Musa Adal, Faris Hailu

“…According to survey study fenugreeks is an important crop with many uses like as spice, food, fodder, and to treat different diseases. They grow mostly on July with legumes like faba bean, chickpea, lentil, grass pea and field pea. …”
Get full text

Association between prostate-specific antigen density and prostate cancer prediction among Nigerian men by Abudu EK, Okuku CN, Akaiso OE, Fabian UA, Udoh EA, Ukpong AE, Kudamnya IJ, Ajayi OO, Uduma FU, Abudu OO, Ekpo BO

“…Results: The mean age for all the patients was 55.7 + 2.6 year while the mean ages of 52.9 + 3.3 years and 65.1 + 11.3 years were for patients with benign and malignant prostate diseases respectively. 26.2 % were adenocarcinomas. …”
Get full text

Enhanced Recovery after Intensive Care (ERIC): study protocol for a German stepped wedge cluster randomised controlled trial to evaluate the effectiveness of a critical care telehe... by Ulrich Mansmann, Claudia Spies, Ursula Marschall, Reinhard Busse, Christine Adrion, Bjoern Weiss, Nicolas Paul, Elke Berger, Jörg Caumanns, Simone Rosseau

“…Besides, there is an increasing number of elderly patients with chronic diseases being treated in the intensive care unit (ICU). …”
Get full text

How, why, where and when people feed birds?—Spatio‐temporal changes in bird‐feeding in Finland by Purabi Deshpande, Anna Haukka, Katja Rönkä, Tuomas Aivelo, Andrea Santangeli, Rose Thorogood, Aleksi Lehikoinen

“…In rural areas, people who reduced feeding more often identified concerns over avian diseases and the effort required to access, clean and refill bird‐feeding sites. …”
Get full text

Salivary peptidomic profiling of chronic gingivostomatitis in cats by matrix‐assisted laser desorption/ionization‐time‐of‐flight mass spectrometry and nanoscale liquid chromatograp... by Sekkarin Ploypetch, Apisit Pornthummawat, Sittiruk Roytrakul, Janthima Jaresitthikunchai, Narumon Phaonakrop, Sabrina Wahyu Wardhani, Sitthichok Lacharoje, Somporn Techangamsuwan

“…We compared the salivary peptide profiles of diseased and healthy cats. The diagnosis of FCGS was confirmed by histopathology. …”
Get full text

Efficacy of Chinese traditional quadruple single pill combination versus valsartan/hydrochlorothiazide for the treatment of hypertension (COSPQ-BP): study protocol for randomised c... by Kai Liu, Yu Yan, Xin Zhang, Yanan Li, Yuanyuan Yao, Lu Liu, Runyu Ye, Si Wang, Xiangyu Yang, Xiaoping Chen, Shanshan Jia, Qingtao Meng, Xianghao Zuo

“…Introduction Hypertension constitutes the primary health burden of cardiovascular diseases, and the global control of blood pressure (BP) remains insufficient. …”
Get full text

Alkaloid Profile, Anticholinesterase and Antioxidant Activities, and Sexual Propagation in <i>Hieronymiella peruviana</i> (Amaryllidaceae) by Olimpia Llalla-Cordova, Javier E. Ortiz, Luciana R. Tallini, Laura Torras-Claveria, Jaume Bastida, Lorena Celina Luna, Gabriela E. Feresin

“…Amaryllidoideae have been studied for their diverse biological activities, particularly for their properties in treating neurodegenerative diseases. This work examines the alkaloidal profile using GC-MS and UPLC-MS/MS of alkaloid-enriched extracts obtained from the leaves and bulbs of <i>H. peruviana</i> and their inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. …”
Get full text