Epigenetic modification regulates the ligamentum flavum hypertrophy through miR-335-3p/SERPINE2/β-catenin signaling pathway by Yongzhao Zhao, Shuai Jiang, Longting Chen, Qian Xiang, Jialiang Lin, Weishi Li

“…Abstract Background Epigenetic modifications have been proved to play important roles in the spinal degenerative diseases. As a type of noncoding RNA, the microRNA (miRNA) is a vital class of regulatory factor in the epigenetic modifications, while the role of miRNAs in the regulation of epigenetic modifications in ligamentum flavum hypertrophy (LFH) has not been fully investigated. …”
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HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

“…Introduction. Cardiovascular diseases (CVDs) continue to be the most common cause of death worldwide, and acute myocardial infarction (AMI) is noteworthy due to its great magnitude. …”
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Is the treatment of ankle osteoarthritis changing over time in Italy? Analysis of temporal trends for fusion and arthroplasty in a population-based study from 2001 to 2022 on the N... by Adriano Cuccu, Elena Manuela Samaila, Enrico Ciminello, Umberto Alfieri Montrasio, Fabrizio Cortese, Stefania Ceccarelli, Tiziana Falcone, Marina Torre

“…Materials and methods International Classification of Diseases, 9th Revision, Clinical Modification (ICD9-CM) codes of interest were identified to browse the Italian National Hospital Discharge Record database. …”
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Clinical effect analysis of posterior longitudinal ligament resection during anterior cervical discectomy and fusion in the treatment of cervical spondylotic myelopathy by NIU Hai‐ying, MENG Xiang‐yu, ZUO Shan‐shan, SUN Xiao‐li, LI Yan, LIU Hong‐lei

“…The posterior longitudinal ligament resection under the microscopy can decompress the diseased segment more thoroughly and significantly improve spinal cord function.…”
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Genetic diversity of barley accessions from East Asian countries in terms of resistance to powdery mildew by R. A. Abdullaev, K. A. Lukina, B. A. Batasheva, O. N. Kovaleva, E. E. Radchenko

“…At the same time, fungal diseases can have a negative impact on its grain yield and quality. …”
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Dual-stream disentangled model for microvascular extraction in five datasets from multiple OCTA instruments by Xiaoyang Hu, Xiaoyang Hu, Jinkui Hao, Quanyong Yi, Yitian Zhao, Jiong Zhang

“…Accurate segmentation of retinal vasculature is essential for eye related diseases measurement and diagnosis. However, noise and artifacts from different imaging instruments can interfere with segmentation, and most existing deep learning models struggle with segmenting small vessels and capturing low-dimensional structural information. …”
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Evaluation of Leea rubra Leaf Extract for Oxidative Damage Protection and Antitumor and Antimicrobial Potential by Nibedita Das, Sanowar Hossain, Jaytirmoy Barmon, Shahnaj Parvin, Mahadi Hasan, Masuma Akter, Ekramul Islam

“…EAF may have great importance in preventing oxidative damage to DNA, erythrocytes, and other cellular components as well as can be a good candidate in cancer chemotherapy and treating infectious diseases caused by antibiotic-resistant bacteria.…”
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Perceptions of Cardiovascular Healthcare Professionals Regarding Clinical Trials: A Survey-Based Study from the Middle East by Zainab Atiyah Dakhil, Hasan Ali Farhan, Mohammed Dheyaa Marsool, Mohammed Saad Qasim, Michele Peters, Jose Leal

“…Background: Low-middle income countries harbor the highest burden of cardiovascular diseases globally, but there is an under-representation of these countries in cardiovascular clinical trials. …”
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Resistance to medically important antimicrobials in broiler and layer farms in Cameroon and its relation with biosecurity and antimicrobial use by Ronald Vougat Ngom, Ronald Vougat Ngom, Andrea Laconi, Roberta Tolosi, Adonis M. M. Akoussa, Stephane D. Ziebe, Vincent M. Kouyabe, Alessandra Piccirillo

“…However, infectious diseases represent the main hindrance in this sector, resulting in overuse and misuse of antimicrobials that can contribute to the emergence and dissemination of antimicrobial resistance (AMR). …”
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Studies on humoral immunity in dogs after use of rabies inactivated vaccines formulated with Montanide ISA 70 VG and GEL 01 adjuvants by A. N. Balashov, M. I. Doronin, A. V. Borisov, D. A. Lozovoy, D. V. Mikhalishin, V. A. Starikov

“…The leading role in the transmission of rabies to humans belongs to diseased dogs; stray animals can be potential sources of rabies agent, which increases the risk of transmitting a deadly virus to humans. …”
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Long-term Home Mechanical Ventilation of Children in İstanbul by Mürüvvet Yanaz, Füsun Ünal, Evrim Hepkaya, Hakan Yazan, Sinem Can Oksay, Ebru Köstereli, Cansu Yılmaz Yeğit, Azer Kılıç Başkan, Zeynep Reyhan Onay, Aynur Gulieva, Aslınur Soyyiğit, Mine Kalyoncu, Hanife Büşra Küçük, Yetkin Ayhan, Almala Pınar Ergenekon, Emine Atağ, Selçuk Uzuner, Nilay Baş İkizoğlu, Ayşe Ayzıt Kılınç, Pınar Ay, Ela Erdem Eralp, Sedat Öktem, Erkan Çakır, Saniye Girit, Zeynep Seda Uyan, Haluk Çokuğraş, Refika Ersu, Bülent Karadağ, Fazilet Karakoç

“…The most common diagnoses were neuromuscular (35.1%) and neurological diseases (25.7%). Among the patients, 49.5% (n = 206) received non-invasive ventilation (NIV), whereas 50.5% (n = 210) received invasive ventilation. …”
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Feasibility and complications of videocapsule endoscopy in dogs weighing 7 kg or less by Camille St‐Jean, Allison Collier, Alex Zur Linden, Alexa Bersenas, Alice Defarges

“…Abstract Background Videocapsule endoscopy (VCE) is a valuable tool for investigating gastrointestinal (GI) diseases in dogs. Its use is not recommended in dogs ≤4.3 kg, because of risks of GI endoscopic capsule (EC) retention and bowel obstruction. …”
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Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus by Yixian Liu, Mengling You, Zhou Zeng, Jing Wang, Rong Rong, Xiaobo Xia

“…An integrated analysis of the datasets for both diseases identified biomarkers and thoroughly examined their biological roles and molecular mechanisms using differential expression analysis (DEA), weighted gene co‐expression network analysis (WGCNA), gene enrichment analysis, machine learning, microRNA (miRNA) and transcription factor analyses, immune infiltration analyses, and single‐cell transcriptome analysis. …”
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The association between visceral fat metabolic score and stroke: mediation by declining kidney function by Yue Cao, Weixing Wen, Hao Zhang, Weiwen Li, Guolin Huang, Yuli Huang

“…Metabolic Score for Visceral Fat (METS-VF), a metric of visceral obesity, has emerged as a novel predictor of metabolic diseases. However, its association with stroke remains unclear. …”
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Data linkage of German statutory health insurance claims data and care needs assessments preceding a population-based cohort study on nursing home admission by Karin Wolf-Ostermann, Dominik Domhoff, Kathrin Seibert, Susanne Stiefler, Dirk Peschke

“…In further steps, the underlying cause of care dependency (International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10)) was added for a higher level of distinction. …”
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Variation in Botryosphaeriaceae from Eucalyptus plantations in YunNan Province in southwestern China across a climatic gradient by Guoqing Li, Bernard Slippers, Michael J. Wingfield, Shuaifei Chen

“…Recently, Botryosphaeriaceae were isolated from diseased plant parts from surveys of Eucalyptus plantations in the YunNan Province, China. …”
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General practitioner-centered rural obesity management: Design, protocol and baseline data of the German HAPpEN pragmatic trial by Marika Haderer, Reiner Hofmann, Tina Bartelmeß, Laura König, Constanze Betz, Mirna Al Masri, Alisa Bader, Natascha von Schau

“…A familial aggregation of obesity, diabetes, and cardiovascular diseases was noted, alongside behavioral challenges such as lack of physical activity (81.8 %) and unhealthy eating habits (56.8 %). …”
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Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor by Toru Momozane, Eriko Fukui, Soichiro Funaki, Makoto Fujii, Yuhei Kinehara, Emiko Ito, Shigeru Miyagawa, Yuko Ohno, Yoshiki Sawa, Meinoshin Okumura, Yasushi Shintani

“…Regenerative medicine has continued to progress for lung biology and lung diseases. Efforts have focused on a variety of different applications for pluripotent stem cells. …”
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The frequency of distribution of the genotypes of the IL4 polymorphism (rs 2243250) in psoriasis and psoriatic arthritis by A. A. Barilo, M. V. Smolnikova, S. V. Smirnova

“…Psoriasis (PS) and psoriatic arthritis (PsA) are multifactorial diseases determined by the result of complex combined interaction of genetic and environmental factors. …”
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Combined surgery for large macular hole in complicated cataract: case report (retracted article) by M.M. Bikbov, O.I. Orenburkina, A.A. Zinnatullin, A.L. Yarmukhametova, A.E. Babushkin, M.R. Kalanov

“…Kalanov </p> <p> Ufa Research Institute of Eye Diseases of the Bashkir State Medical University, Ufa, Russian Federation </p> <p> The only effective treatment for macular holes (MH) is surgery. …”
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