Supply-Side Practices and Constraints of the Kola Nut (Cola nitida (Vent) Schott. and Endl.) Value Chain in Ghana: A Descriptive Evidence by Frederick Amon-Armah, Solomon Sefa Oduro, Eric Kofi Doe, Moses Asani, Daniel Nyadanu, Sampson Konlan

“…Low market price of nuts (61.5%) and pests and diseases (60.4%) were the most reported constraints to kola nut production. …”
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The obesity paradox in osteoporosis risk among older adults is mostly driven by women: a population-based prospective study by Qingfeng Luo, Shiyong Zhang, Zixin Liang, Danni Wang, Yanlin Zhong, Bin Xia, Peng Xie, Can Wang, Jinqiu Yuan, Ziji Zhang, Xingsheng Li

“…Abstract Objectives The obesity paradox is common among older adults at risk for various diseases. Although this paradox has also been observed in the association between obesity and osteoporosis, the available evidence remains controversial. …”
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Chemical Composition and Larvicidal Activity of Lavandula angustifolia Subsp. angustifolia and Lavandula dentata Spp. dentata Essential Oils against Culex pipiens Larvae, Vector of... by Fouad El-Akhal, Amal Ramzi, Abdellah Farah, Yassine Ez Zoubi, Moussa Benboubker, Khalid Taghzouti, Abdelhakim El Ouali Lalami

“…The Culex pipiens mosquito (Diptera: Culicidae) is highly suspected to be the vector responsible for the spread of several parasitic and viral diseases. The use of synthetic insecticides is generally the preferred method of controlling these mosquitoes’ proliferation. …”
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NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study by Aya El Gendy, Fawzia Hassan Abo Ali, Shereen A. Baioumy, Sara I. Taha, Mahy El -Bassiouny, Osama M. Abdel Latif

“…NOD-like receptor pyrin domain containing 3 (NLRP3) gene dysregulation can result in numerous immunological and inflammatory diseases. Objective: This case-control study aimed to determine the association between the NLRP3 inflammasome (rs10754558) single nucleotide polymorphism (SNP) and the occurrence, severity and etiology of CSU. …”
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The effect of failed transfer of passive immunity and agammaglobulinemia on the occurrence of preweaning diarrhea, pneumonia, and mortality in Holstein calves by Mely T. Olivera, Jesús Mellado, José E. García, Juan A. Encina, Perpetuo Álvarez, Ulises Macías-Cruz, Leonel Avendaño, Miguel Mellado

“…Research highlights: These results reaffirm that FPI and AG 24 h post-calving increase the risk of preweaning diarrhea and pneumonia; also, diarrhea is a significant risk factor for pneumonia. These diseases alone or co-occurring in the calves markedly increase preweaning mortality. …”
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Comprehensive Analysis of <i>blaCTX-M1</i> Gene Expression Alongside <i>iutA</i>, <i>csgA</i>, and <i>kpsMII</i> Virulence Genes in Septicemic <i>Escherichia coli</i> Using Real-Ti... by Mohsen Karbalaei, Mojgan Esmailpour, Valentyn Oksenych, Majid Eslami

“…The key to treating these diseases is having sophisticated diagnostic tools and using antibiotics cautiously.…”
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Changes in anaphylaxis trends and characteristics in emergency department admissions in Türkiye: From 2015 to 2021 based on the Ministry of Health database by Elif Soyak Aytekin, MD, Seda Şirin, MD, Esra Kıratlı Nalbant, MD, Naim Ata, MD, Ahmet Sertçelik, MD, Mustafa Mahir Ülgü, MD, Şuayip Birinci, MD, Koray Harmancı, MD, Zülfikar Akelma, MD

“…Codes from the International Classification of Diseases, 10th revision (ICD-10), were used to identify anaphylaxis. …”
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Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population by O. Bulgakova, A. Kussainova, A. Kakabayev, А. Kausbekova, R. Bersimbaev

“…Lung cancer is a problem of great concern and one of the commonest cancer diseases worldwide and in the Republic of Kazakhstan in particular. …”
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Genetic causality between insomnia and specific orthopedic conditions: Insights from a two-sample Mendelian randomization study by Mingyi Yang, Jiale Xie, Yani Su, Ke Xu, Pengfei Wen, Xianjie Wan, Hui Yu, Zhi Yang, Lin Liu, Peng Xu

“…Objective: To investigate the genetic causality for the insomnia and common orthopedic diseases, such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), osteoporosis (OP), and gout (GT). …”
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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage by Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

“…Noise pollution is a known health risk factor and evidence for cardiovascular diseases associated with traffic noise is growing. …”
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Charlson syndrome index predicted survival in pancreatic cancer patients received immunotherapy by Nan Zhang, Nan Zhang, Shiyun Chen, Yue Shi, Zhikuan Wang, Ru Jia, Guanghai Dai, Guanghai Dai

“…ObjectiveThe Charlson Comorbidity Index (CCI) is a widely utilized assessment tool for evaluating the mortality rate among patients with chronic diseases and tumors. Currently, there is a dearth of research investigating the correlation between CCI and survival rates in advanced pancreatic cancer patients received immunotherapy. …”
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Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery and synergistic pancreatic cancer therapy by Diana Peixoto, João M. Ravasco, Barbara Blanco-Fernandez, Francisco Veiga, Angel Concheiro, João Conde, Ana Cláudia Paiva-Santos, Carmen Alvarez-Lorenzo

“…Pancreatic ductal adenocarcinoma (PDAC) remains one of the most feared diseases worldwide owing to its poor prognosis, negligible therapeutic advances, and high mortality. …”
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Evaluation of intranasal TLR2/6 agonist INNA-051: safety, tolerability and proof of pharmacology by Francesca A. Mercuri, Scott White, Hayley A. McQuilten, Charlotte Lemech, Stephan Mynhardt, Rana Hari, Ping Zhang, Nicole Kruger, Grant McLachlan, Bruce E. Miller, Nicholas P. West, Ruth Tal-Singer, Christophe Demaison

“…Background Local priming of the innate immune system with a Toll-like receptor (TLR)2/6 agonist may reduce morbidity and mortality associated with viral respiratory tract infections, particularly for the elderly and those with chronic diseases. The objectives of the present study were to understand the potential of prophylactic treatment with a TLR2/6 agonist as an enhancer of innate immunity pathways leading to accelerated respiratory virus clearance from the upper airways. …”
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Evaluation of Childhood Traumas, Depressive Symptoms, and Dissociative Experiences in Tinnitus Cases by Mustafa Altıntaş, Deniz Sarlak, Erdinç Özturk, Osman Celbiş

“…In addition, 77.78% of patients did not visit a psychiatrist and 75.56% did not have any chronic diseases. The mean total score of Childhood Trauma Scale for the tinnitus group was 54.37±10.17, the mean total score of The Hospital Anxiety and Depression Scale for the tinnitus group in the depression subscale was 12.22±5.41 and in the anxiety subscale was 10.54±3.5, and Dissociative Experiences was 13.48±4.68. …”
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Noise-induced ribbon synapse loss in the mouse basal cochlear region does not reduce inner hair cell exocytosis by David Oestreicher, David Oestreicher, Alfonso Mauro Malpede, Alfonso Mauro Malpede, Annalena Reitmeier, Annalena Reitmeier, Carolin Paula Bräuer, Carolin Paula Bräuer, Laura Schoch, Laura Schoch, Nicola Strenzke, Nicola Strenzke, Tina Pangrsic, Tina Pangrsic, Tina Pangrsic

“…Noise-induced hearing loss is one of the most common forms of hearing loss in adults and also one of the most common occupational diseases. Extensive previous work has shown that the highly sensitive synapses of the inner hair cells (IHCs) may be the first target for irreparable damage and permanent loss in the noise-exposed cochlea, more precisely in the cochlear base. …”
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Behavior changes to promote preconception health: a systematic review by Maiko Suto, Kimiko Inaoka, Daichi Suzuki, Aya Nitamizu, Naoko Arata, Erika Ota

“…Abstract Background Preconception care is expected to prevent diseases, promote health, and improve pregnancy outcomes. …”
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Identification of natural phytochemicals as AKT2 inhibitors using molecular docking and dynamics simulations as potential cancer therapeutics by Jibon Kumar Paul, Mahir Azmal, Md Naimul Haque Shohan, Mohua Mrinmoy, ANM Shah Newaz Been Haque, Omar Faruk Talukder, Ajit Ghosh

“…Given that AKT2 also plays a role in neuronal survival and plasticity, these compounds may have potential applications in neurodegenerative diseases such as Alzheimer's, warranting further investigation into their dual therapeutic relevance.…”
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Metabolic Phenotyping of Adipose-Derived Stem Cells Reveals a Unique Signature and Intrinsic Differences between Fat Pads by Camille Lefevre, Baptiste Panthu, Danielle Naville, Sylvie Guibert, Claudie Pinteur, Bénédicte Elena-Herrmann, Hubert Vidal, Gilles J. P. Rautureau, Anne Mey

“…While the expansion of subcutaneous adipose tissues (SAT) is protective in obesity, that of visceral adipose tissues (VAT) correlates with the emergence of metabolic diseases. Maintained in fat pads throughout life, adipose stem cells (ASC) are mesenchymal-like stem cells with adipogenesis and multipotent differentiation potential. …”
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Association of Wrist Circumference and Waist-to-Height Ratio with Cardiometabolic Risk Factors among Type II Diabetics in a Ghanaian Population by Christian Obirikorang, Yaa Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Emmanuel Toboh, Evans Adu Asamoah, Bright Amakwaa, Emmanuella Nsenbah Batu, Peter Brenya

“…Using Framingham risk scores, 61% of the subjects had elevated 10-year risk of developing cardiovascular diseases (CVDs), with no significant difference in gender prevalence. …”
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Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice by Fengen Wang, Hongbin Zhou, Ligang Deng, Lei Wang, Jingqing Chen, Xihong Zhou

“…Inflammation and oxidative stress play key roles in the process of aging and age-related diseases. Since serine availability plays important roles in the support of antioxidant and anti-inflammatory defense system, we explored whether serine deficiency affects inflammatory and oxidative status in D-galactose-induced aging mice. …”
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