Identification of improved signal peptides for heterologous expression in Saccharomyces using a screen that exploits Gaussia luciferase by Ginevra Camboni, Jared Cartwright, Gideon Grogan

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Combining biosensor and metabolic network optimization strategies for enhanced l-threonine production in Escherichia coli by Zhenqiang Zhao, Rongshuai Zhu, Xuanping Shi, Fengyu Yang, Meijuan Xu, Minglong Shao, Rongzhen Zhang, Youxi Zhao, Jiajia You, Zhiming Rao

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Directed evolution of α-ketoisovalerate decarboxylase for improved isobutanol and 3-methyl-1-butanol production in cyanobacteria by Hao Xie, Afshan Begum, Laura H. Gunn, Peter Lindblad

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LatentDE: latent-based directed evolution for protein sequence design by Thanh V T Tran, Nhat Khang Ngo, Viet Thanh Duy Nguyen, Truong-Son Hy

Subjects: “…directed evolution…”
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Machine learning-assisted rational design and evolution of novel signal peptides in Yarrowia lipolytica by Zizhao Wu, Wenhao Chen, Yuxiang Hong, Yongkai Wang, Peng Xu

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Research Progress in Enzyme Engineering Strategies to Improve the Thermal Stability of Enzymatic Time-Temperature Indicators by PENG Huakang, ZHANG Huanzhi, WANG Chenyue, WANG Yao

Subjects: “…enzymatic time-temperature indicators; enzyme engineering; directed evolution; rational design; auxiliary design…”
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SERS-based microdroplet platform for high-throughput screening of Escherichia coli strains for the efficient biosynthesis of D-phenyllactic acid by Lin Hu, Ruoshi Luo, Dan Wang, Fanzhen Lin, Kaixing Xiao, Yaqi Kang

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Structural studies of Parvoviridae capsid assembly and evolution: implications for novel AAV vector design by Heather A. Noriega, Qizhao Wang, Daozhan Yu, Xiang Simon Wang

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Pre-pandemic artificial MERS analog of polyfunctional SARS-CoV-2 S1/S2 furin cleavage site domain is unique among spike proteins of genus Betacoronavirus by Andreas Martin Lisewski

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Corrigendum: SERS-based microdroplet platform for high-throughput screening of Escherichia coli strains for the efficient biosynthesis of D-phenyllactic acid by Lin Hu, Ruoshi Luo, Dan Wang, Fanzhen Lin, Kaixing Xiao, Yaqi Kang

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Semi-supervised prediction of protein fitness for data-driven protein engineering by Alicia Olivares-Gil, José A. Barbero-Aparicio, Juan J. Rodríguez, José F. Díez-Pastor, César García-Osorio, Mehdi D. Davari

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Directed evolution and modular integration of a high-affinity ICOS-L variant for potent T cell–mediated tumor elimination by Ji Yeon Ha, Tae Wook Song, Petrina Jebamani, Sun-Gu Lee, Sang Taek Jung

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PRIME, a temperature-guided language model revolutionizes protein engineering by Yuanxi Yu, Qianhui Wang, Yike Zou

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Enzyme and cofactor engineering to increase d-xylonate dehydratase activity for improved d-1,2,4-butanetriol production from d-xylose by Jingwen Chen, Zhangyu Liu, Dandan Mai, Sheng Xu, Xin Wang, Kequan Chen

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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

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Engineering of l-threonine and l-proline biosensors by directed evolution of transcriptional regulator SerR and application for high-throughput screening by Wei Pu, Jinhui Feng, Jiuzhou Chen, Jiao Liu, Xuan Guo, Lixian Wang, Xiaojia Zhao, Ningyun Cai, Wenjuan Zhou, Yu Wang, Ping Zheng, Jibin Sun

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