Cold Agglutinin Disease Unfurled in Laboratory and Blood Bank: A Little Poignant Observation Can Speak a Lot! by Archana Shetty, Gurudatta Murthy, Bharadwaj Golithadka

“…A detailed workup confirmed a diagnosis of CA type of AIHA. The case reiterates the importance of good interdepartmental coordination between clinicians, laboratory, and blood bank, which helped clinch the diagnosis of CAD through the correlation of clinical findings, blood counts, and immunological and biochemical parameters.…”
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Invasive Aspergillosis in the Intensive Care Unit by Anna Zubovskaia, Jose A. Vazquez

“…In this article, we will discuss the challenges and pitfalls of the diagnosis and management of invasive aspergillosis in an ICU setting, along with a review of the current literature that is pertinent and specific to this population.…”
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Two Cases of Leigh Syndrome in One Family: Diagnostic Challenges and Clinical Management Experience in Latvia by Arta Katkevica, Madara Kreile, Ieva Grinfelde, Gita Taurina, Ieva Micule, Iveta Dzivite-Krisane, Arta Smite-Laguna, Ieva Malniece

“…The difficulties encountered establishing a diagnosis for the first proband and the effective prenatal diagnosis for the second offspring that led to termination of the pregnancy are discussed.…”
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Anterior Segment Imaging in Ocular Surface Squamous Neoplasia by Sally S. Ong, Gargi K. Vora, Preeya K. Gupta

“…Nevertheless, anterior segment imaging has not replaced histopathology’s role as the gold standard in confirming diagnosis.…”
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A Rare Case of Pure Primary Large Cell Neuroendocrine Carcinoma of the Gallbladder by Rodney E. Shackelford, Ekin Ozluk, Jehan Abdulsattar, Terry C. Lairmore, Quyen Chu, Eric X. Wei

“…Due to the extreme rarity of such disease entity, accurate diagnosis and proper management are essential for the best clinical outcome.…”
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Recurrent Syncope, a Clue in Amyloid Cardiomyopathy by Julian A. Marin-Acevedo, Catalina Sanchez-Alvarez, Ali A. Alsaad, Ricardo J. Pagán

“…The article illustrates the role of advanced cardiac imaging in the diagnosis of the disease with a focused literature review. …”
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Synovial Osteo-chondromatosis: in Regards with a Case by Dianarelys Villafuerte Delgado, Mercy Guadalupe Heras Heras, Félix González Pérez

“…The case is presented because it is an infrequent medical entity in which imaging studies have a vital role for the diagnosis and posterior treatment.…”
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Giant Ulcerative Dermatofibroma by Turgut Karlidag, Erol Keles, Israfil Orhan, Mehmet Erkan Kaplama, Bengu Cobanoglu

“…The rarely seen erosions and ulcerations may cause difficulties in the diagnosis. Dermatofibrosarcoma protuberans, which is clinically and histopathologically of malignant character, displays difficulties in the diagnosis since it has similarities with basal cell carcinoma, epidermoid carcinoma, and sarcomas. …”
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Orbital cellulitis secondary to sinusitis. Case presentation by Oslaymi Yero Lorente, Miriellis Rodriguez Benítez, Manuel Enrique Rodríguez Valdés, Yelenis Abreu Jáuregui

“…It is concluded that the main elements are early diagnosis and multidisciplinary evaluation.…”
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Glomus Tumor of the Cheek: A Case Report by Konstantinos Veros, Konstantinos Markou, Chrysa Filitatzi, Dionysios E. Kyrmizakis

“…Though facial location is rare, the diagnosis of a glomus tumor should be considered in cases of undiagnosed painful facial nodules or chronic facial pain. …”
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Merkel Cell Carcinoma of the Left Eyelid with Metastasis to the Left Submandibular Lymph Nodes: A Case Report and Brief Review by Caroline Casey, Nina Gallo, Samuel Gallo

“…MCC is rare but very often lethal making early diagnosis challenging although critical. There are only a few cases that have reported MCC of the eyelid making it often hard to identify in clinic. …”
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Angioimmunoblastic T Cell Lymphoma Mimicking Chronic Urticaria by Mohleen Kang, Nitasha Bhatia, Adrienne Sauder, Mirela Feurdean

“…A minority have skin lesions at the time of diagnosis, more commonly in the form of nonspecific maculopapular rash with or without pruritus. …”
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Cutaneous metastasis as a breast carcinoma presentation. A case report by Daymi Martínez Rodríguez, Elizabet Fernández López, Susana Graciela Hernández Delgado

“…The case of a patient diagnosed with cutaneous metastasis of a lobular breast carcinoma is presented, where the skin lesions were the starting point for more conclusive studies and the neoplastic diagnosis. This case is presentation due to the need to highlight the importance of the differential diagnosis that the dermatologist must perform, given the real possibility of metastatic skin lesions, in patients who consult with unusual skin lesions.…”
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Cardiac Fibroelastoma: A Rare Cause of Stroke in Young Adults by Ahmad Mirdamadi, Mohsen MirmohammadSadeghi, Mahfar Arasteh, Mojgan Gharipour

“…Transesophageal echocardiography (TEE) revealed two distinct mobile LV masses suggesting a diagnosis of papillary fibroelastoma. CT angiography and histopathological studies confirmed this diagnosis.…”
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Yellow Fever: It worth a review in the current epidemiological context by Miguel Ángel Serra Valdés

“…If there is a delay in the diagnosis, it shall contribute substantially to the possibility of its introduction in the territory and an epidemiologic outbreak.…”
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A 41-Year-Old Patient with a Rare Cause of Severe Abdominal Sepsis Misdiagnosed as PID by Anastasia Mikuscheva, David Becker, Mark Thompson-Fawcett

“…In a patient who has not completed family planning, the diagnosis is often made with a low threshold and treatment started on a low suspicion of diagnosis to avoid a negative impact on fertility. …”
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An Unusual Case of Systemic Lupus Erythematosus and Hemophagocytic Syndrome by Saika Sharmeen, Nazia Hussain

“…This case represents the importance of prompt diagnosis and treatment of such a potentially fatal clinical syndrome.…”
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Abdominal Wall Endometrioma. Report of Two Cases by Tahiluma Santana Pedraza, Jorge Luís Estepa Pérez, Juan Carlos Estepa Torres

“…Wide excision of the tissue and histological examination were performed, confirming the diagnosis. The postoperative course was uneventful. …”
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Otosyphilis with Clinical and Serologic Responses with Weekly Intramuscular Penicillin: A Case Report and Literature Review by Ali Etemady-Deylamy, Getahun Abate

“…Otosyphilis is a rare form of syphilis with an extremely high rate of complications. Early diagnosis is essential to prevent a complete loss of hearing and decrease mortality. …”
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Small Cell Lung Cancer with Positive Anti-Hu Antibodies Presenting as Gastroparesis by David N Moskovitz, Kenneth V Robb

“…The potential benefit of early diagnosis has prompted investigations into markers of this disease. …”
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