Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference by Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva

“…In this review we focus on diseases of the endocrine system and discuss potential RNA-targeted therapeutic opportunities in diabetes mellitus, including monogenic beta cell diabetes, and obesity, including syndrome obesity and monogenic obesity, as well as in non-monogenic or complex endocrine disorders. …”
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Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat by Ghupurjan Gheni, Norihide Yokoi, Masayuki Beppu, Takuro Yamaguchi, Shihomi Hidaka, Ayako Kawabata, Yoshikazu Hoshino, Masayuki Hoshino, Susumu Seino

“…We recently established a novel animal model of obese type 2 diabetes (T2D), the Zucker fatty diabetes mellitus (ZFDM) rat strain harboring the fatty mutation (fa) in the leptin receptor gene. …”
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Assessment of Clinical Features in HIV-Infected Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention in China by Ying Liu, Yongfu Chen, Yiwei Hao, Jing Xiao, Bei Li, Leidan Zhang, Junyan Han, Hongxin Zhao

“…We compared demographic characteristics, angiographic features, and 1-year outcomes of 48 PLWH versus 48 HIV-negative controls matched for age (±2 years), sex, diabetes mellitus, and year of PCI (±2 years) in Beijing Ditan Hospital, Capital Medical University from January 2008 to November 2020. …”
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Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study by Cheng-Hao Weng, Ching-Chih Hu, Shir-Hwa Ueng, Chun-Chen Yu, Chung-Yee Hui, Ja-Liang Lin, Chih-Wei Yang, Cheng-Chieh Hung, Ching-Wei Hsu, Tzung-Hai Yen

“…Univariate logistic regression showed that APD was significantly associated with diabetes mellitus (DM), reduced levels of intact parathyroid hormone (iPTH) and albumin (Alb), reduced dialysis adequacy () and urea reduction rate (URR), and elevated levels of high-sensitivity C-reactive protein (hsCRP). …”
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The Comorbidity of Depression and Diabetes Is Involved in the Decidual Protein Induced by Progesterone 1 (Depp1) Dysfunction in the Medial Prefrontal Cortex by Chen Xu, Mengxing Liao, Shize Zhang, Yuang Chen, Xinyue Shulai, Guangji Wang, Jiye Aa

“…Background: There is a high rate of depressive symptoms such as irritability, anhedonia, fatigue, and hypersomnia in patients with type 2 diabetes mellitus (T2DM). However, the causes and underlying mechanisms of the comorbidity of depression and diabetes remain unknown. …”
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Nutritional composition and organoleptic quality of instant local black rice (cempo ireng) with moderate glycemic index by Dian Nurhayati Aprinia, Nirbaya Arindra, Permata Nusa Cassandra, Soekopitojo Soenar, Lukas Kurniawan Adi, Dwi Handoko Dody, Hapsari Anindya, Faza Sepbrina Aurelia, Oktavia Wahyuningsih Prastiwi Dwi, Ayu Puspitasari Diah, Athaya Nazhira, Yusuf Al Badwani Muhammad, Aulia Araminta Diza

“…This research aims to develop instant rice from local black rice variety, Cempo Ireng, that is safe for diabetes mellitus. Instant black rice was made through the process of soaking in sodium citrate, washing, cooking using a rice cooker, freezing in the freezer for 24 hours, thawing at room temperature, and drying using a dehydrator. …”
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Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

“…Diabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes mellitus. Although studies have indicated the therapeutic potential of mesenchymal stem cells (MSCs) for DKD, the underlying molecular mechanisms remain unclear. …”
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Proceso de atención de enfermería aplicado a un adulto mayor con pie diabético by Fatima Del carmen Bernal Corrales, Ximena Alessandra Guevara Sánchez, Liz Katherine Heredia Roalcaba, Lesly Andrea Serrepe Rodas

“…Caso clínico: Adulto mayor internado en el servicio de medicina en un hospital nivel I por presentar una úlcera en el primer dedo del pie derecho, con una profundidad de 0,5 x 0,5 cm de diámetro, de dos meses de evolución, además de un edema en el miembro inferior derecho, con antecedente de diabetes mellitus no controlada. Métodos: Estudio de caso único de enfoque cualitativo mediante la aplicación del proceso de atención de enfermería basado en el modelo de valoración de Marjory Gordon y las taxonomías de diagnósticos (NANDA), resultados (NOC) e intervenciones de enfermería (NIC). …”
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Pulmonary Mucormycosis – An Experience from a Tertiary Care Center in Southern India: A PULM MUCOR Study by Ashwin Oliver Arul, K. Rajiv Karthik, Devasahayam Jesudas Christopher

“…Conclusions: Pulmonary mucormycosis requires a high index of suspicion, and a delay in the diagnosis leads to complications and poor outcomes. Uncontrolled diabetes mellitus and chronic kidney disease were the conventional predisposing factors for pulmonary mucormycosis. …”
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Navigating the Risk Landscape in ST-Elevation Myocardial Infarction Patients Postpercutaneous Coronary Intervention: A Narrative Review by Utkarsh Gaur, Charuta Gadkari, Aditya Pundkar

“…In this population, diabetes mellitus, hypertension, and reduced cardiac function all dramatically increase the risk of poor outcomes. …”
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Association between Red Blood Cell Distribution Width and In-Hospital Mortality among Congestive Heart Failure Patients with Diabetes among Patients in the Intensive Care Unit: A R... by Kai Zhang, Yu Han, Yu Xuan Gao, Fang Ming Gu, Tianyi Cai, Rui Hu, Zhao Xuan Gu, Jia Ying Liang, Jia Yu Zhao, Min Gao, Bo Li, Dan Cui

“…Nevertheless, the relationship between RDW and in-hospital mortality in the intensive care unit (ICU) among patients with both congestive heart failure (CHF) and diabetes mellitus (DM) remains uncertain. Methods. This retrospective study utilized data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, a comprehensive critical care repository. …”
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The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class? by Ricardo Godinho, Cristina Mega, Edite Teixeira-de-Lemos, Eugénia Carvalho, Frederico Teixeira, Rosa Fernandes, Flávio Reis

“…Incretin-based therapies, the most recent therapeutic options for type 2 diabetes mellitus (T2DM) management, can modify various elements of the disease, including hypersecretion of glucagon, abnormal gastric emptying, postprandial hyperglycaemia, and, possibly, pancreatic β cell dysfunction. …”
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Islet organoids: a new hope for islet transplantation in diabetes by Xuemei Yu, Chengkong Liu, Zheng Kuang, Siyuan Song, Limin Tian, Yi Wang, Yi Wang

“…Diabetes mellitus, including Type 1 diabetes (T1D) and advanced Type 2 diabetes (T2D), remains a major global health challenge due to the destruction or dysfunction of insulin-producing β-cells. …”
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Resultados de la aplicación de Heberprot-P para el tratamiento de la úlcera del pie diabético by Gloria Lara Calderín, Ana Teresa Fernández Vidal, Anabel Geroy Fernández, Anays de la Caridad Núñez Herrera, Eduardo Milián Lara

“…<strong>Fundamento:</strong> la diabetes mellitus es una enfermedad crónica. Una de sus complicaciones frecuentes es el pie diabético, para cuyo tratamiento se utiliza el Heberprot-P. …”
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Epidemiology and Control of diabetes - tuberculosis comorbidity in Eswatini: protocol for the prospective study of tuberculosis patients on predictive factors, treatment outcomes a... by Diederick E Grobbee, Kerstin Klipstein-Grobusch, Kennedy Otwombe, Victor Williams, Alinda Vos

“…Introduction Previous studies indicate people with diabetes mellitus (DM) may have varying treatment outcomes when receiving treatment for tuberculosis (TB) and that TB infection or its treatment may predispose them to develop an abnormal blood glucose or type 2 DM. …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin... by Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Marek Szudrowicz, Magdalena Łanocha, Jan Jakub Kulczycki, Karol Turkiewicz, Katarzyna Woźnica, Maciej Lesiak, Adrian Doroszko

“…Although percutaneous coronary intervention (PCI) continues to evolve, type 2 diabetes mellitus (T2DM) is a well-established marker of poor clinical prognosis after PCI, which is mainly attributed to the rapid progression of atherosclerosis requiring recurrent revascularizations. …”
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Contextual awareness, response and evaluation (CARE) of diabetes in poor urban communities in Ghana: the CARE diabetes project qualitative study protocol by Leonard Baatiema, Daniel Llywelyn Strachan, Lydia Osetohamhen Okoibhole, Irene Akwo Kretchy, Mawuli Kushitor, Raphael Baffour Awuah, Olutobi Adekunle Sanuade, Ernestina Korleki Danyki, Samuel Amon, Kafui Adjaye-Gbewonyo, Haim Yacobi, Megan Vaughan, Ann Blandford, Publa Antwi, Hannah Maria Jennings, Daniel Kojo Arhinful, Ama de-Graft Aikins, Edward Fottrell, the CARE Diabetes Team

“…Six qualitative studies utilising a range of methodologies are proposed in this protocol to generate a contextual understanding of type 2 diabetes mellitus in an urban poor population. They focus on community, care provider, and policy stakeholder perspectives with a focus on food markets and environmental influences, the demand and supply of health services, and the history of the Ga Mashie community and its inhabitants. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…The two main obstacles after islet transplantation are alloreactive T-cell-mediated graft rejection and recurrence of autoimmune diabetes mellitus in recipients. T cells play a central role in determining the outcome of both autoimmune responses and allograft survival. …”
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Clinical profile and outcomes in patients with moderate to severe aortic stenosis with or without concomitant chronic kidney disease by Jinghao Nicholas Ngiam, Ching-Hui Sia, Nicholas Wen Sheng Chew, Tze Sian Liong, Zi Yun Chang, Chi Hang Lee, Wen Ruan, Edgar Lik-Wui Tay, William Kok-Fai Kong, Huay Cheem Tan, Tiong-Cheng Yeo, Kian Keong Poh

“…The CKD group was older (78.0 ± 10.3 vs. 72.1 ± 12.9 years, P < 0.001), with a higher prevalence of hypertension, diabetes mellitus, hyperlipidaemia and ischaemic heart disease. …”
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Interventions for Type 2 Diabetes Prevention and Management Among Indigenous Children and Youth: A Systematic Review by Edmund Wedam Kanmiki, Yaqoot Fatima, Thuy Linh Duong, Roslyn Von Senden, Tolassa W. Ushula, Abdullah A. Mamun

“…ABSTRACT Introduction Indigenous populations experience a disproportionately higher burden of early onset of type 2 diabetes mellitus (T2DM). To contribute towards addressing this health disparity, evidence‐based culturally appropriate interventions are urgently needed. …”
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