The impact of uric acid on musculoskeletal diseases: clinical associations and underlying mechanisms by Jing Zhang, Na Sun, Wanhao Zhang, Wenjie Yue, Xiaochen Qu, Xiaochen Qu, Zhonghai Li, Zhonghai Li, Gang Xu, Gang Xu

“…Serum urate (SU) levels are significantly elevated in conditions such as gout, type 2 diabetes (T2D), obesity, and other metabolic syndromes. …”
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Smoking Induces the Circulating Levels of Matrix Metalloproteinase-9 and Its Association with Cardiovascular Risk in Young Smokers by Dinesh NATH, Meera SHIVASEKAR, V. M. VINODHINI

“…Group one consisted of 120 healthy individuals with no physical and mental illness, group two consisted of 120 active smokers with a heart disease, and group three consisted of 120 active smokers with a heart disease and diabetes, who attended Sri Ramaswamy Memorial Hospital for cardiology checkup at the age of 20-55 years. …”
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Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway by Maryam Darabi, Shima Byagowi, Shabnam Fayezi, Masoud Darabi, Shahab Mirshahvaladi, Mehdi Sahmani

“…The Δ6-desaturase (Δ6D), also known as fatty acid desaturase 2, is a regulatory enzyme in de novo fatty acid synthesis, which has been linked to obesity and diabetes. The aim of the present study was to investigate the effect of peroxisome proliferative-activated receptor δ (PPARδ) agonist and MEK/ERK1/2-dependent pathway on the expression of Δ6D in human pancreatic carcinoma cell line PANC-1. …”
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Genome-Wide Association Study of Metabolic Syndrome in Koreans by Seok Won Jeong, Myungguen Chung, Soo-Jung Park, Seong Beom Cho, Kyung-Won Hong

“…Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. …”
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An overview of healthcare-associated Candida auris outbreaks in Ministry of Health hospitals-Saudi Arabia 2020-2022; Retrospective multicentric study. by Khalid H Alanazi, Hala M Roushdy, Waad I ALzubaidi, Arwa S Alanazi, Nawal M Alanazi, Ahlam H Alamri, Yahya I Alnshbah, Nawaf M Al Almatrafi, Zainah M Al Shahrani, Adel S Alanazi, Nasser H Alshanbari

“…Approximately 18.8% of cases were diabetes, and 18.5% were hypertensive. Central lines were discovered in 37.7% of the cases. …”
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The impact of COVID-19 on HIV care: a comprehensive analysis of patient and healthcare providers experiences at the largest HIV treatment center in Ghana by Peter Puplampu, Justice K. Baah, Karl Osei Afoduo, Bright A. Adjei, Araba Abaidoo-Myles, Victor G. Davila-Roman, George B. Kyei, Collins S. Ahorlu

“…This meant many patients with chronic diseases like hypertension, diabetes, and hyperlipidemia did not get the necessary physician review during the pandemic's peak. …”
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Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study by Swati Dhar, Reena Yadav, Akash Tomar

“…It is unclear if serum zinc levels are correlated with polycystic ovary syndrome (PCOS) and its pathophysiology, although relation between diabetes and insulin resistance has been established. …”
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IUPHAR themed review: The gut microbiome in schizophrenia by Srinivas Kamath, Elysia Sokolenko, Kate Collins, Nicole S.L. Chan, Natalie Mills, Scott R. Clark, Francine Z. Marques, Paul Joyce

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COVID-19 in patients presenting with malaria-like symptoms at a primary healthcare facility in Accra, Ghana. by Issabella Asamoah, Mildred Adusei-Poku, Priscilla Vandyck-Sey, Allen Steele-Dadzie, Atta Senior Kuffour, Albert Turkson, Ivy Asantewaa Asante, Kantanka Addo-Osafo, Quaneeta Mohktar, Bright Adu, Yaw A Afrane, Kwamena W C Sagoe

“…Comorbidities reported were hypertension, asthma and diabetes. One hundred and thirteen (37.8%) of the study participants had prior exposure to SARS CoV-2 and (34/51) 66.7% of Astrazeneca vaccinated patients had no IgG antibody.…”
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Hidden in Plain Sight: Incidental Diagnosis of Metastatic Papillary Thyroid Microcarcinoma Without Radiologically Apparent Thyroid Tumor by Natalie Rivera Vargas, MD, Moises Matos, MD, Mustafa Kinaan, MD, FACE

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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

“…Glucagon-like peptide 1 receptor agonists (GLP-1RAs), traditionally used in the treatment of type 2 diabetes, are becoming increasingly appreciated for their diverse applications. …”
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Systematic review of the association between thyroid disorders and hyperprolactinemia by Adeel Ahmad Khan, Rohit Sharma, Fateen Ata, Sondos K Khalil, Arwa Saed Aldien, Muhammad Hasnain, Amna Sadiq, Ammara Bint I Bilal, Wasique Mirza

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Incidência de hipertensão arterial e desfechos na população idosa de São Paulo: estudo de coorte SABE by Isabela Martins Oliveira, Yeda Aparecida de Oliveira Duarte, Dirce Maria Trevisan Zanetta

“…A incidência de HA associou-se positivamente à idade ≥75 anos, pré-hipertensão, doença coronariana, hipercolesterolemia e diabetes. A baixa filtração glomerular foi o desfecho de saúde mais observado em 2016 entre os hipertensos. …”
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Effect of Health Education on Healthy Nutrition and Physical Activity among Female Teachers Aged 40–60 Years in Asmara, Eritrea: A Quasiexperimental Study by Helen Gebretatyos, Soliana Amanuel, Lidia Ghirmai, Ghidey Gebreyohannes, Eyasu H. Tesfamariam

“…Moreover, chronic illness such as diabetes, hypertension, heart diseases, and osteoporosis are prevalent at this time. …”
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Personal glucose meter-based portable method for creatine kinase assay by Jinhwan Lee, Yejin Oh, Hyoyong Kim, Sangmo Lee, Hyun Gyu Park

“…By allowing simultaneous tracking of CK and glucose levels with the same PGM device, this approach is particularly beneficial for diabetes mellitus (DM) patients, empowering them to proactively manage their health and reduce the risk of muscle-related complications.…”
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Thyroid Dysfunction Prevalence and Risk Factors in the Southeastern Part of Bangladesh: A Cross‐Sectional Study by Muhammad Shahadat Hossen, Md. Mahmodul Islam, Abhijit Das, Md. Abdur Rahman Ripon, Mohammad Tohidul Amin, Mohammad Anwarul Basher, Md. Mamun Or Rashid

“…Interestingly, the studied population also exhibited higher rates of comorbidities including gastritis, diabetes, and cardiovascular diseases. Conclusion According to the study's findings, it is advised to concentrate on educating Bangladeshis about thyroid problems, particularly female population. …”
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Blood pressure, gallstones, and age at first cholecystectomy in U.S. adults: a cross-sectional study by Yue Zhang, Ruifeng Duan, Xin Chen, Lijuan Wei

“…After adjustment for age, gender, race, diabetes, and hypercholesterolemia, HTN was significantly associated with gallstones in individuals aged 48 years (OR = 1.39; 95% CI: 1.03, 1.88). …”
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A Narrative Review of Key Risk Factors for Severe Illness Following SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus Infection by Angela Branche, Mayur Ramesh, Beverly Francis

“…., chronic obstructive pulmonary disease), diabetes, chronic kidney disease, and obesity, are key factors that predispose individuals to SARS-CoV-2-, influenza-, and RSV-related severe outcomes. …”
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Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver by M. Del Ben, L. Polimeni, F. Baratta, S. Bartimoccia, R. Carnevale, L. Loffredo, P. Pignatelli, F. Violi, F. Angelico

“…After stratification by cytokeratin-18 tertiles, a significant progression of body mass index, HOMA-IR, triglycerides, urinary 8-iso-PGF2α, soluble NOX2-derived peptide, and of the prevalence of diabetes and severe steatosis was found, while HDL-cholesterol and adiponectin progressively decreased. …”
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Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome by Roozbeh Khosravi, Khady Ka, Ting Huang, Saeed Khalili, Bich Hong Nguyen, Belinda Nicolau, Simon D. Tran

“…Obesity has been associated with increased comorbidities, such as coronary artery disease, diabetes, and destructive periodontal disease. Obesity is also part of a group of risk factors occurring together in an individual, which is referred to as metabolic syndrome. …”
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