Metformin Use and Survival in Patients with Advanced Extrahepatic Cholangiocarcinoma: A Single-Center Cohort Study in Fuyang, China by Jinqing Wu, Yabo Zhou, Guizhou Wang

“…Metformin is an oral antidiabetic agent that has been widely prescribed for the treatment of type II diabetes. In recent years, anticancer properties of metformin have been revealed for numerous human malignancies. …”
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Factors Influencing Postoperative Inpatient Rehabilitation Requirement After Surgical Intervention for Isolated Hip Fracture: A Multicenter Study by Daniel J. Lynch, Andrew Romero, James P. McFadden, Peter Zeblisky, Huazhi Liu, Darwin Ang

“…This cohort had a longer average hospital stay, higher incidence of diabetes, congestive heart failure, chronic renal failure, history of cerebrovascular accident, functionally dependent health status, hypertension, chronic obstructive pulmonary disease, dementia, baseline anticoagulation therapy, and history of myocardial infarction. …”
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Obesity Cut-Off Points Using Prepregnancy Body Mass Index according to Cardiometabolic Conditions in Pregnancy by Renata O. Neves, Alexandre da S. Rocha, Bruna O. de Vargas, Daniela C. Kretzer, Salete de Matos, Marcelo Z. Goldani, Lisia von Diemen, José A. de A. Magalhães, Juliana R. Bernardi

“…To suggest cut-off points for body mass index (BMI) using gestational hypertension, preeclampsia, and gestational diabetes mellitus (GDM) as cardiometabolic conditions in pregnancy. …”
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Predicting Factors Affecting Survival Rate in Patients Undergoing On‐Pump Coronary Artery Bypass Graft Surgery Using Machine Learning Methods: A Systematic Review by Alireza Jafarkhani, Behzad Imani, Soheila Saeedi, Amir Shams

“…Notably, five factors—age, ejection fraction, diabetes mellitus, a history of cerebrovascular disease or accidents, and renal function—were consistently identified across multiple studies as significant predictors of postsurgical survival. …”
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Disfunción renal: fármacos, medios de contraste radiológicos y sistema renina angiotensina by José Antonio Chipi Cabrera, Julio Alexander Silveira Echavarría, Aliuska Naranjo Hernández, Darnelys Méndez Lemus, Giraldo Hurtado Báez

“…El continuo envejecimiento poblacional, unido al incremento de la prevalencia de enfermedades crónicas no trasmisibles, entre las que se destacan la diabetes mellitus y la hipertensión arterial, como principales causas de deterioro de la función renal en las personas, ha hecho que con el paso de los años se introduzcan nuevos fármacos, más potentes, para la prevención y tratamiento de dichas entidades, lo que obliga a estar al día en el conocimiento de las características farmacocinéticas de estos medicamentos para evitar posibles efectos tóxicos, esto implica hacer una valoración previa de la función renal antes de introducir cualquier sustancia que pudiera ser potencialmente nefrotóxica. …”
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Metabolic Perturbations and Severe COVID-19 Disease: Implication of Molecular Pathways by Ersilia Nigro, Fabio Perrotta, Rita Polito, Vito D’Agnano, Filippo Scialò, Andrea Bianco, Aurora Daniele

“…Among comorbidities observed in SARS-CoV-2 positive patients, hypertension (68.3%) and type 2-diabetes (30.1%) are the most frequent conditions. …”
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Fetuin-A Characteristics during and after Pregnancy: Result from a Case Control Pilot Study by Serdar Farhan, Ammon Handisurya, Jelena Todoric, Andrea Tura, Giovanni Pacini, Oswald Wagner, Katharina Klein, Rudolf Jarai, Kurt Huber, Alexandra Kautzky-Willer

“…Fetuin-A has been associated with gestational diabetes mellitus (GDM). We investigated fetuin-A levels during and after pregnancy in women with GDM. …”
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Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling by Chengshuo Zhang, Le Li, Bochao Zhao, Ao Jiao, Xin Li, Ning Sun, Jialin Zhang

“…Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. …”
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A scoping review of biopsychosocial risk factors and co-morbidities for common spinal disorders. by Bart N Green, Claire D Johnson, Scott Haldeman, Erin Griffith, Michael B Clay, Edward J Kane, Juan M Castellote, Shanmuganathan Rajasekaran, Matthew Smuck, Eric L Hurwitz, Kristi Randhawa, Hainan Yu, Margareta Nordin

“…Risk factors were reported for group 1: non-specific low back pain (smoking, overweight/obesity, negative recovery expectations), non-specific neck pain (high job demands, monotonous work); group 2: degenerative spinal disease (workers' compensation claim, degenerative scoliosis), and group 3: spinal tuberculosis (age, imprisonment, previous history of tuberculosis), spinal cord injury (age, accidental injury), vertebral fracture from osteoporosis (type 1 diabetes, certain medications, smoking), and neural tube defects (folic acid deficit, anti-convulsant medications, chlorine, influenza, maternal obesity). …”
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Evaluation of Risk Factors of Venous Thromboembolism in Imam Sadiq Teaching Hospital at Babylon City by Intisar Mahdi Kadhim Almurshedi, Amel Mustafa Kamil, Aqeel Abbas Noaman

“…There was no significant link between medical history and the outcome of this investigation (hypertension, diabetes, heart disease, and lung diseases) ... except kidney disease was likely at a higher risk of VTE than participants who had no kidney disease. …”
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Protracted Hypocalcemia following 3.5 Parathyroidectomy in a Kidney Pancreas Recipient with a History of Robotic-Assisted Roux-en-Y Gastric Bypass by Hugo Bonatti, Naureen Iqbal, Catherine Kling, Willie Melvin, James Broome

“…A 41-old-year morbidly obese female with c-peptide negative diabetes mellitus and renal failure had RYGBP. Following significant weight loss she underwent simultaneous pancreas-kidney transplantation. …”
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Maximal Glycemic Difference, the Possible Strongest Glycemic Variability Parameter to Predict Mortality in ICU Patients by Thanaphruet Issarawattana, Rungsun Bhurayanontachai

“…Higher glycemic variability was identified in the nonsurvivor group regardless of preexisting diabetes mellitus. The maximal blood glucose difference and coefficient of variation of the blood glucose were the two strongest parameters for predicting intensive care unit mortality in this study.…”
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Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes by Kexin Wang, Hongyan Li, Hongxing Wang, Jun-hui Wang, Feng Song, Yu Sun

“…Our finding may provide novel evidence for the future application of irisin in the treatment of Alzheimer’s disease and the memory dysfunction in diabetes mellitus.…”
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Nutritional Status of Patients on Maintenance Hemodialysis at Muhimbili National Hospital in Dar es Salaam, Tanzania: A Cross-Sectional Study by Puneet Bramania, Paschal Ruggajo, Rimal Bramania, Muhiddin Mahmoud, Francis Furia

“…The longer duration on hemodialysis, having diabetes mellitus, and being single were associated with increased risk for malnutrition in multivariate logistic regression. …”
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Characterization of patients with ischemic cerebrovascular disease and cognitive impairment. Cienfuegos, 2018 by Beatriz Perdomo Borges, Teresa Rodríguez Rodríguez, Marianela Fonseca Fernández, Isabel Urquiza Pozo, Idalmis Luisa Martínez Serrano, Belkis Rosa Bilaboy Pérez

“…The risk factors mostly associated with the disease were high blood pressure, diabetes mellitus and smoking. The majority of patients did not suffer depression after cerebral infarction.…”
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The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years by Ngoc Minh Pham, Daigo Yoshida, Makiko Morita, Guang Yin, Kengo Toyomura, Keizo Ohnaka, Ryoichi Takayanagi, Suminori Kono

“…Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. There were inverse associations of coffee consumption with serum UA concentrations and hyperuricemia in men regardless of adjustment for covariates. …”
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Clinical Efficacy Evaluation of Sirolimus in Congenital Hyperinsulinism by Somayyeh Hashemian, Reza Jafarzadeh Esfehani, Siroos Karimdadi, Rahim Vakili, Daniel Zamanfar, Amirhossein Sahebkar

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Serum uric acid to creatinine ratio as a predictor of insulin resistance, β cell function, and metabolic syndrome in normal Korean adults: a cross-sectional study by Misuk Oh, Soo Hyun Cho

“…Materials and methods This study included 14,984 participants without diabetes mellitus or gout who participated in the 2019–2021 Korea National Health and Nutrition Examination Survey. …”
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Kaempferol improves glucose uptake in skeletal muscle via an AMPK-dependent mechanism by William T. Moore, Jing Luo, Dongmin Liu

“…Insulin resistance is a hallmark of type-2 diabetes (T2D) pathogenesis. Because skeletal muscle (SkM) is the major tissue for insulin-mediated glucose disposal, insulin resistance in SkM is considered a major risk factor for developing T2D. …”
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Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century by J.-F. Stoltz, N. de Isla, Y. P. Li, D. Bensoussan, L. Zhang, C. Huselstein, Y. Chen, V. Decot, J. Magdalou, N. Li, L. Reppel, Y. He

“…Different clinical applications are under study (cardiac insufficiency, atherosclerosis, stroke, bone and cartilage deterioration, diabetes, urology, liver, ophthalmology, and organ’s reconstruction). …”
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