PSYCHOSOCIAL ILLNESS IN CHILDREN WITH THALASSEMIA: A CASE-CONTROL STUDY by Erum Afzal, Muhammad Aslam Sheikh, Sajjad Hussain Bhaba, Tanveer Ahmed, Imran Iqbal, Muhammad Khalid Iqbal

“…Regarding characteristics of thalassemia 74 %( n=37) patients were diagnosed within 1st year of life, while 26 %( n=13) after 1st year.64 %( n=32) had well controlled and 36 %( n=18) poor controlled disease. 20%(n=10) had developed Diabetes mellitus,2%(n=1) heart failure,74%(37) growth failure,76%(n=38) hemolytic facial features and 72%(n=36)skin discoloration. …”
Get full text

Association between intraoperative fluid management and postoperative outcomes in living kidney donors: a retrospective cohort study by Ja Eun Lee, Chisong Chung, Sunghae Park, Kyo Won Lee, Gaab Soo Kim

“…The following covariates were used: age, sex, body weight, height, diabetes mellitus, hypertension, preoperative estimated glomerular filtration rate, operation duration, surgeon, nephrectomy side, and estimated blood loss. …”
Get full text

Clinical Features and Predictors of Lethal Outcome in Tick-Borne Encephalitis: A Retrospective Study from Lithuania by G. Rynkevič, E. Žilinskas, D. Streckytė, D. Radzišauskienė, R. Mameniškienė

“…Patients with the meningoencephalomyelitic form of TBE less often had headache on admission, more often had diabetes, and had fewer lymphocytes in the CSF (all p<0.05). …”
Get full text

Using a robust model to detect the association between anthropometric factors and T2DM: machine learning approaches by Nafiseh Hosseini, Hamid Tanzadehpanah, Amin Mansoori, Mostafa Sabzekar, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…Abstract Background The aim of this study was to evaluate the potential models to determine the most important anthropometric factors associated with type 2 diabetes mellitus (T2DM). Method A dataset derived from the Mashhad Stroke and heart atherosclerotic disorders (MASHAD) study comprising 9354 subject aged 65 − 35. 25% (2336 people) of subjects were diabetic and 75% (7018 people) where non-diabetic was used for the analysis of 10 anthropometric factors and age that were measured in all patients. …”
Get full text

Adenylate cyclase 10 promotes brown adipose tissue thermogenesis by Anupam Das, Christine Mund, Eman Hagag, Ruben Garcia-Martin, Eleftheria Karadima, Anke Witt, Mirko Peitzsch, Andreas Deussen, Triantafyllos Chavakis, Thomas Noll, Vasileia Ismini Alexaki

Get full text

Evaluation of the Relationship between Nutritional Status of COVID-19 Patients Admitted to the ICU and Patients’ Prognosis: A Cohort Study by Parsa Mohammadi, Hesam Aldin Varpaei, Alireza Khafaee pour khamseh, Mostafa Mohammadi, Mojgan Rahimi, Amirhossein Orandi

“…There was a statistically significant association between chronic kidney disease (CKD) and mNUTRIC risk (OR = 13.5, 95% CI (1.89–16.05), P=0.002), diabetes mellitus (DM) and MNA risk (OR = 2.82, 95% CI (1.01–7.83), P=0.041), hypertension (HTN) and MNA risk (OR = 5.63, 95% CI (2.26–14.05), P<0.001), and malignancy and mNUTRIC risk (P=0.048). …”
Get full text

Long-Term Dietary Nitrate Supplementation Does Not Prevent Development of the Metabolic Syndrome in Mice Fed a High-Fat Diet by V. B. Matthews, R. Hollingshead, H. Koch, K. D. Croft, N. C. Ward

“…A reduction in NO bioavailability is thought to contribute to endothelial dysfunction, an early risk factor for both cardiovascular disease and type 2 diabetes. Dietary nitrate, through the nitrate-nitrite-NO pathway, may provide an alternate source of NO when the endogenous eNOS system is compromised. …”
Get full text

Investigation of the Feasibility and Safety of a Highly Intensive Penetration Technique for Recanalization in Severe Calcified Femoropopliteal Occlusive Lesions: A Retrospective Ob... by Shinsuke Mori, Keisuke Hirano, Yusuke Setonaga, Toshihiko Kishida, Tomoya Fukagawa, Kohei Yamaguchi, Masafumi Mizusawa, Masakazu Tsutsumi, Norihiro Kobayashi, Yoshiaki Ito

“…The proportion of men, patients with hypertension, patients with diabetes mellitus, and patients on hemodialysis was 78%, 59%, 41%, and 44%, respectively. …”
Get full text

Second Trimester Umbilical Cord Coiling Index and Perinatal Outcomes by Yusuf Aytaç Tohma, Mehmet Metin Altay, Derya Turgut, Selcan Coşkun, Eylem Ünlübilgin, Sertaç Esin, Orhan Gelişen, Okyar Erol

“…Perinatal problems such as preeclampsia, gestational diabetes mellitus (GDM), intrauterine growth restriction (IUGR), small for gestational age (SGA) and birth weight, gestational age at birth, and newborn intensive care unit need were recorded. …”
Get full text

Clinical characteristics and outcomes in Asian patients with heart failure with mildly reduced ejection fraction by Julian Cheong Kiat Tay, Shaw Yang Chia, Siew Hui Michelle Koh, David Kheng Leng Sim, Ping Chai, Seet Yoong Loh, Fazlur Rehman Jaufeerally, Sheldon Shao Guang Lee, Patrick Zhan Yun Lim, Jonathan Yap

“…HFmrEF patients were more likely to be gender neutral, of mid-range age and have concomitant diabetes mellitus, hyperlipidaemia, peripheral vascular disease and coronary artery disease (P < 0.001). …”
Get full text

Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro by Zhou Zhou, Weiliang Sun, Ying Liang, Yanxiang Gao, Wei Kong, Youfei Guan, Juan Feng, Xian Wang

“…Uncontrolled activity of T cells mediates autoimmune and inflammatory diseases such as multiple sclerosis, inflammatory bowel diseases, rheumatoid arthritis, type 1 diabetes, and atherosclerosis. Recent findings suggest that enhanced activity of interleukin-17 (IL-17) producing T helper 17 cells (Th17 cells) plays an important role in autoimmune diseases and inflammatory diseases. …”
Get full text

Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…There were significant differences in urinary AD7c-NTP levels between subjects with and without a history of coronary heart disease or diabetes. Urinary AD7c-NTP levels were not related to years of education, nature of work, family history of dementia, a history of hypertension, stroke, anemia, or thyroid dysfunction. …”
Get full text

Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCO2R Using the Hemolung Respiratory Assist System by Ramiro Saavedra-Romero, Francisco Paz, John M. Litell, Julia Weinkauf, Carina C. Benson, Lisa Tindell, Kari Williams

“…This patient’s multiple comorbid conditions included obesity, hypertension, type 2 diabetes mellitus, and hypercholesterolemia. On her fifth day of admission at the referring hospital, her worsening hypoxemia prompted endotracheal intubation during which she developed pneumothorax. …”
Get full text

TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis by Xiang Hu, Jing Zhou, Sha-sha Song, Wen Kong, Yan-Chuan Shi, Lu-Lu Chen, Tian-Shu Zeng

Get full text

Exploring the boundaries of anastomotic leak: experience in a high-volume center by Carolina Riscanevo Bobadilla, Gloria Flórez Dussan, Jorge Vargas, Liliana Suarez, German Jimenez, Carlos Gonzalez, Andrea Carolina Córdoba, Wilmar Martín, Diego Olivera, Raúl Guevara

“…Notably, 18.5% smoked, 11.1% had lung disease, and 9.3% had heart disease or diabetes. Chest tomography was used in 60% of cases, followed by endoscopy in 35.2%. …”
Get full text

Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions by Chi-Hang Yee, Ching Leung, Yuki Yu-Ting Wong, Sylvia Lee, Jenny Li, Pauline Kwan, Winnie Chiu-Wing Chu, Vincent Chung-Tong Mok, Chi-Fai Ng

“…Presence of WML, hypertension, or diabetes mellitus was not found to be correlated with storage urinary symptoms or OAB-V8 total score. …”
Get full text

The optimal treatment of invasive ductal and lobular carcinoma occurring at the same time needs to be established by Supriya Peshin, Rafi Iftekher, Rabia Iqbal, Shagun Singh, Moka Nagaishwarya

“…The complexity of this case was further heightened by a significant family history of breast and colon cancers, and comorbid conditions including borderline diabetes, hypertension and coronary artery disease (CAD), which required careful therapeutic consideration to balance efficacy and tolerability. …”
Get full text

Body Mass Index and 1-Year Unplanned Readmission in Chinese Patients with Acute Myocardial Infarction: A Retrospective Cohort Study by Dandan Sun, Qingyun Zhang, Wei Li, Haichen Wang

“…Covariates involved in this study included age, gender, TC, triglyceride, HDL-C, LDL-C, PT, APTT, INR, creatinine, HGB, LVEF, discharge medication, marital status, educational level, COPD, diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension. …”
Get full text

CADD based designing and biological evaluation of novel triazole based thiazolidinedione coumarin hybrids as antidiabetic agent by Anchal Sharma, Anmol Narang, Nitish Kumar, Rupali Rana, Megha, Pooja, Muskan Dhir, Harmandeep Kaur Gulati, Jyoti, Aanchal Khanna, Jatinder Vir Singh, Sukhraj Kaur, Preet Mohinder Singh Bedi

“…Additionally, density functional theory (DFT) analyses were performed to assess the stability and reactivity of potential diabetes mellitus drug candidates. Dynamic simulation studies further elucidated the stability and interaction dynamics of the top-ranked compound I-1. …”
Get full text

Spatial epidemiology based on the analysis of COVID-19 in Africa by Joyce Akhalakwa Mukolwe, John Kamwele Mutinda, Amos Kipkorir Langat

“…The analysis indicates that demographic factors such as the proportion of the population aged 65 and older, and health-related factors such as diabetes prevalence, have a substantial impact on the distribution of cases. …”
Get full text