Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway by Maryam Darabi, Shima Byagowi, Shabnam Fayezi, Masoud Darabi, Shahab Mirshahvaladi, Mehdi Sahmani

“…The Δ6-desaturase (Δ6D), also known as fatty acid desaturase 2, is a regulatory enzyme in de novo fatty acid synthesis, which has been linked to obesity and diabetes. The aim of the present study was to investigate the effect of peroxisome proliferative-activated receptor δ (PPARδ) agonist and MEK/ERK1/2-dependent pathway on the expression of Δ6D in human pancreatic carcinoma cell line PANC-1. …”
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Genome-Wide Association Study of Metabolic Syndrome in Koreans by Seok Won Jeong, Myungguen Chung, Soo-Jung Park, Seong Beom Cho, Kyung-Won Hong

“…Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. …”
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Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study by Swati Dhar, Reena Yadav, Akash Tomar

“…It is unclear if serum zinc levels are correlated with polycystic ovary syndrome (PCOS) and its pathophysiology, although relation between diabetes and insulin resistance has been established. …”
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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

“…Glucagon-like peptide 1 receptor agonists (GLP-1RAs), traditionally used in the treatment of type 2 diabetes, are becoming increasingly appreciated for their diverse applications. …”
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Incidência de hipertensão arterial e desfechos na população idosa de São Paulo: estudo de coorte SABE by Isabela Martins Oliveira, Yeda Aparecida de Oliveira Duarte, Dirce Maria Trevisan Zanetta

“…A incidência de HA associou-se positivamente à idade ≥75 anos, pré-hipertensão, doença coronariana, hipercolesterolemia e diabetes. A baixa filtração glomerular foi o desfecho de saúde mais observado em 2016 entre os hipertensos. …”
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Effect of Health Education on Healthy Nutrition and Physical Activity among Female Teachers Aged 40–60 Years in Asmara, Eritrea: A Quasiexperimental Study by Helen Gebretatyos, Soliana Amanuel, Lidia Ghirmai, Ghidey Gebreyohannes, Eyasu H. Tesfamariam

“…Moreover, chronic illness such as diabetes, hypertension, heart diseases, and osteoporosis are prevalent at this time. …”
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Personal glucose meter-based portable method for creatine kinase assay by Jinhwan Lee, Yejin Oh, Hyoyong Kim, Sangmo Lee, Hyun Gyu Park

“…By allowing simultaneous tracking of CK and glucose levels with the same PGM device, this approach is particularly beneficial for diabetes mellitus (DM) patients, empowering them to proactively manage their health and reduce the risk of muscle-related complications.…”
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Thyroid Dysfunction Prevalence and Risk Factors in the Southeastern Part of Bangladesh: A Cross‐Sectional Study by Muhammad Shahadat Hossen, Md. Mahmodul Islam, Abhijit Das, Md. Abdur Rahman Ripon, Mohammad Tohidul Amin, Mohammad Anwarul Basher, Md. Mamun Or Rashid

“…Interestingly, the studied population also exhibited higher rates of comorbidities including gastritis, diabetes, and cardiovascular diseases. Conclusion According to the study's findings, it is advised to concentrate on educating Bangladeshis about thyroid problems, particularly female population. …”
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Blood pressure, gallstones, and age at first cholecystectomy in U.S. adults: a cross-sectional study by Yue Zhang, Ruifeng Duan, Xin Chen, Lijuan Wei

“…After adjustment for age, gender, race, diabetes, and hypercholesterolemia, HTN was significantly associated with gallstones in individuals aged 48 years (OR = 1.39; 95% CI: 1.03, 1.88). …”
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Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver by M. Del Ben, L. Polimeni, F. Baratta, S. Bartimoccia, R. Carnevale, L. Loffredo, P. Pignatelli, F. Violi, F. Angelico

“…After stratification by cytokeratin-18 tertiles, a significant progression of body mass index, HOMA-IR, triglycerides, urinary 8-iso-PGF2α, soluble NOX2-derived peptide, and of the prevalence of diabetes and severe steatosis was found, while HDL-cholesterol and adiponectin progressively decreased. …”
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Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome by Roozbeh Khosravi, Khady Ka, Ting Huang, Saeed Khalili, Bich Hong Nguyen, Belinda Nicolau, Simon D. Tran

“…Obesity has been associated with increased comorbidities, such as coronary artery disease, diabetes, and destructive periodontal disease. Obesity is also part of a group of risk factors occurring together in an individual, which is referred to as metabolic syndrome. …”
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Intrahepatic Cholestasis of Pregnancy and Associated Adverse Maternal and Fetal Outcomes: A Retrospective Case-Control Study by Mingjuan Luo, Mengyang Tang, Feng Jiang, Yizhen Jia, Robert Kien Howe Chin, Wei Liang, Hu Cheng

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4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…Chronic inflammatory diseases such as periodontitis have been associated with increased risk for various medical conditions including diabetes and cardiovascular disease. Endotoxin (lipopolysaccharide, LPS), derived from gram-negative periodonto-pathogens, can induce the local accumulation of mononuclear cells in the inflammatory lesion, increasing proinflammatory cytokines and matrix metalloproteinases (MMPs). …”
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Acute Exposure to a Precursor of Advanced Glycation End Products Induces a Dual Effect on the Rat Pancreatic Islet Function by Ghada Elmhiri, Luiz Felipe Barella, Didier Vieau, Sylvaine Camous, Paulo C. F. Mathias, Latifa Abdennebi-Najar

“…Advanced glycation end products, known as AGEs, are a major risk factor for diabetes onset and maintenance. Methylglyoxal (MG), a highly reactive metabolite of glucose, is a precursor for the generation of endogenous AGEs. …”
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A Nonfunctioning Pituitary Macroadenoma Presenting as Cyclical Vomiting and Severe Hyponatremia in a Young Female by Dinuka S. Warapitiya, Dimuthu Muthukuda, W. A. H. P. Sanjeewa, Kushalee Poornima Jayawickreme, Shyama Subasinghe

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The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography by Anne B. Gregory, Kendra K. Lester, Deborah M. Gregory, Laurie K. Twells, William K. Midodzi, Neil J. Pearce

“…Cardiac risk factor prevalence (e.g., diabetes, hypertension, and hyperlipidemia) significantly increased with increasing BMI. …”
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Frequency and Predictors of Pneumonia After Isolated Coronary Artery Bypass Grafting (CABG): A Single-Center Study by Ozgur Baris, Tugba Asli Onyilmaz, Huseyin Kaya

“…In patients with POP, diabetes mellitus (<i>p</i> = 0.03) and chronic kidney disease (<i>p</i> = 0.048) prevalence was higher, cardiopulmonary bypass (CPB) (<i>p</i> = 0.01) and cross-clamp time (<i>p</i> = 0.003) was longer, LDH levels (<i>p</i> = 0.017) were higher, hemoglobin (<i>p</i> = 0.012) and albumin (<i>p</i> = 0.015) levels were lower, and lymphocyte % (<i>p</i> = 0.04) was lower; prevalence of COPD and length of stay (LOS) in hospital tended to be higher (both <i>p</i> < 0.06). …”
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Comparing Fetal Weight Estimates in the Third Trimester: Clinical Examination Findings, Ultrasonographic Estimation, and Actual Birth Weight by Ayesha Ghaffar, Sabeen Ashraf, Hafiza Alia Akbar Khan, Saba Yousaf, Tallat Farkhanda, Amartur Rabbal

“…The patients with PIH, preeclampsia, eclampsia, anaemia, chronic renal disease, diabetes and conditions such as polyhydramnios, oligohydramnios, and congenital fetal anomalies were excluded from the study. …”
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The Validity Of 75gms OGTT For Detection Of GDM Keeping 100gms OGTT As Gold Standard by Shazia Mehreen, Muhammad Usman, Kashif Rauf, Saima Naz, Muhammad Abdul Rab Faisal Sultan, Muhammad Akram Randhawa

“…Advanced screening and diagnosis of gestational DM, and its effective treatment not only inhibit adverse perinatal and maternal outcomes but also save the lives of both child and mother from diabetes in future. …”
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The impact of chronic disease diagnoses on smoking behavior change and maintenance: Evidence from China by Xinxin Chi, Xihua Liu, Cong Li, Wen Jiao

“…A diagnosis of a mild chronic disease, such as hypertension, diabetes, asthma, chronic lung disease, liver disease, or gastric disease, had more negligible and transient effects on smoking behavior. …”
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