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5241
Actinomicosis pulmonar. Presentación de un caso
Published 2017-01-01“…Se presenta el caso de un paciente de 17 años de edad, procedente del África, con antecedentes de diabetes mellitus y malnutrición proteico-energética, atendido por médicos cubanos de misión en ese continente. …”
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5242
Exploring the associations between the biomechanical and psychological mechanistic pathways of lower back pain development amongst persons with lower-limb amputation: A study proto...
Published 2025-01-01“…<h4>Introduction</h4>The global rise in lower-limb amputations is mainly due to diabetes and vascular complications. Amputations cause serious physical and psycho-social disabilities which impair locomotion and compromise patients quality of life. …”
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5243
Sensitive and label-free fluorescent microRNA detection via catalytic DNAzyme assembly initiated primer exchange reaction
Published 2025-01-01“…MicroRNAs (miRNAs) have an intricate connection to the development of human diseases, such as malignancies, diabetes, and viral infections; therefore, their rapid and precise identification is critical in disease diagnosis and treatment. …”
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5244
Sarcoid of the Upper Humerus Found Incidentally on MR Images Obtained for Work-Up of Rotator Cuff Tear Where Compromised Tissue Quality Was a Concern for Surgical Success
Published 2018-01-01“…Her medical history includes type 2 diabetes, depression, and fatigue. She had chronic shoulder pain that worsened after her dog jerked on the leash. …”
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5245
PPARγ and Its Agonists in Chronic Kidney Disease
Published 2020-01-01“…The major risk factors for CKD include obesity, diabetes, and cardiovascular diseases. Understanding the key process involved in the disease development may lead to novel interventive strategies, which is currently lagging behind. …”
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5246
Investigation of Pharmacokinetic Parameters of Trelagliptin in Egyptian Volunteers Using Sensitive LC-MS/MS: A Comparative Study with a Japanese Population
Published 2021-01-01“…Trelagliptin (TLN) is a novel once-weekly antidiabetic drug that enhanced the patient compliance in type 2 diabetes. TLN analysis and bioanalysis literature review showed many methods for TLN assay either in dosage form or as biological fluids (pharmacokinetic parameters), but all those methods did not consider the full details dealing with biological assay of TLN. …”
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5247
Association of CYP11A1 Polymorphisms with Recurrent Pregnancy Loss in the Female Population of Punjab
Published 2023-07-01“…The aetiologies of RPL include uterine anatomic anomalies, uncontrolled diabetes mellitus, untreated hypothyroidism, parental chromosomal abnormalities, antiphospholipid antibody syndrome, thrombophilia, genetic abnormalities and infections. …”
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5248
Development of a Predictive Model of Tuberculosis Transmission among Household Contacts
Published 2019-01-01“…Ten variables (gender, age, TB history, diabetes, HIV, index patient’s drug resistance, socioeconomic status, spoligotypes, and the index-contact share sleeping room status) filtered through the LASSO regression technique were finally included in the predictive model. …”
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5249
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5250
Deep learning-based prediction of autoimmune diseases
Published 2025-02-01“…In particular, the average area under the ROC curve (AUC) of the AutoY model exceeded 0.93 in the prediction of all the diseases, and the AUC value reached 0.99 in two diseases, type 1 diabetes and multiple sclerosis. These results demonstrate the high accuracy, stability, and good generalization ability of the two models, which makes them promising tools in the field of autoimmune disease prediction and provides support for the use of the TCR bank for the noninvasive detection of autoimmune disease non-invasive detection is supported.…”
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5251
Acromegaly: Role of Surgery in the Therapeutic Armamentarium
Published 2012-01-01“…Patients may also present arterial hypertension, diabetes mellitus, colonic polyps, cardiomegaly, neurological and endocrine changes secondary to the presence of a GH-secreting tumor in pituitary or extrapituitary origin, or eutopic hypothalamic GHRH hypersecretion and peripheral GHRH hypersecretion. …”
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5252
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature
Published 2017-01-01“…A 71-year-old female with a history of type 2 diabetes, hypertension, and ischaemic heart disease presented with painless haematuria for 2 months’ duration. …”
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5253
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Published 2025-02-01“…This study leverages protein engineering to enhance ACE2’s therapeutic potential for treating conditions such as respiratory viral infections, acute respiratory distress syndrome, and diabetes. Surrogate substrates used in traditional high-throughput screening methods for peptidases often fail to accurately mimic native substrates, leading to less effective enzyme variants. …”
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5254
Cytokines and HCV-Related Disorders
Published 2012-01-01“…The most important systemic HCV-related extrahepatic diseases—mixed cryoglobulinemia, lymphoproliferative disorders, thyroid autoimmune disorders, and type 2 diabetes—are associated with a complex dysregulation of the cytokine/chemokine network, involving proinflammatory and Th1 chemokines. …”
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5255
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5256
Comparison of natural and artificial vasopressin deficiency: why the latter is lethal?
Published 2016-05-01“…The naturally occuring AVP-deficient Brattleboro rat has a framshift mutation in the neurophysin portion resulting in cental diabetes insipidus. In its hypothalamus AVP is not produced, while in certain peripheral tissues it may be expressed, suggesting the existence of a different synthetic pathway. …”
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5257
Vasomotor Syndrome its Association with Cardiovascular Disease Risk Factors
Published 2024-12-01“…The variables studied were: the intensity of the syndrome vasomotor, through the Pérez Piñeiro Cuban scale and risk factors for cardiovascular disease: overweight and obesity, abdominal obesity, high blood pressure, smoking, diabetes mellitus type 2, hypercholesterolemia and sedentary lifestyle. …”
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5258
Social interaction and successful aging in elderly with chronic diseases
Published 2024-12-01“…Social interaction plays a crucial role in supporting successful aging, particularly among elderly individuals with chronic diseases such as hypertension, diabetes mellitus, and heart disease. This study aims to analyze the impact of social interaction on successful aging among elderly people visiting the Andalas Health Center in Padang City. …”
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5259
Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis
Published 2017-01-01“…Polymorphism in VDR causes alterations in the functioning of vitamin D, leading to type 1 diabetes (T1D) predisposition. The aim of the present study was to determine VDR gene polymorphism in association with T1D in Pakistanis. …”
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5260
Physical activity at home during the COVID-19 lockdown in India: Need of the hour for optimum physical health and psychological resilience
Published 2020-07-01“…It can reduce high blood pressure, help manage overweight, improve immune regulation, reduce the risk of getting heart disease, type 2 diabetes, stroke, and various cancers- all conditions which increase vulnerability to COVID-19. …”
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