Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis by Ermia Mousavi Mohammadi, Mohsen Rajati, Hossein Zarrinfar

“…A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa. …”
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Cardiovascular Complications in CKD Patients: Role of Oxidative Stress by Elvira O. Gosmanova, Ngoc-Anh Le

“…While traditional CVD risk factors, including diabetes, hypertension, hyperlipidemia, obesity, physical inactivity, may be more prevalent among CKD patients, these factors seem to underestimate the accelerated cardiovascular disease in the CKD population. …”
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Pharma TARP: A Troubled Asset Relief Program for Novel, Abandoned Projects in the Pharmaceutical Industry by Tamas Bartfai, Graham Vaughan Lees

“…Society has a real need for the drugs that are no longer going to be developed for, among others, drug-resistant epilepsy, neuropathic and cancer pain, type-2 diabetes, obesity, and schizophrenia. The authors propose a radical response by the U.S. government and the National Institutes of Health to rescue these abandoned projects, and to continue selected programs for drug approval by the U.S. …”
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Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk? by Ahmad Aljada, Kshitij Ashwin Shah, Shaker A. Mousa

“…Cardiovascular disease is a major cause of morbidity and mortality among people with type 2 diabetes mellitus. The peroxisome proliferator-activated receptor (PPAR) agonists have a significant role on glucose and fat metabolism. …”
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A Review of the Potential for Cardiometabolic Dysfunction in Youth with Spina Bifida and the Role for Physical Activity and Structured Exercise by Kevin R. Short, Dominic Frimberger

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Lactobacillus gasseri Causing Bilateral Empyema by Angela Esquibel, Ala S. Dababneh, Bharath Raj Palraj

“…This is a case of a 49-year-old male with previously undiagnosed type two diabetes mellitus who presented with a 3-month history of cough and was found to have right sided Lactobacillus gasseri empyema for which he underwent video-assisted thoracoscopic surgery (VATS) with chest tube placement. …”
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PPARs: Protectors or Opponents of Myocardial Function? by Christine J. Pol, Melissa Lieu, Konstantinos Drosatos

“…Activators of PPARs are used for treating several metabolic complications, such as diabetes and hyperlipidemia that are directly or indirectly associated with HF. …”
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Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…We highlight the application of immunopeptidomics in Type 1 Diabetes (T1D), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA). …”
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Induction of Immunological Tolerance by Oral Anti-CD3 by Andre Pires da Cunha, Howard L. Weiner

“…Parenteral administration of anti-CD3 monoclonal antibody is an approved therapy for transplantation in humans and is effective in autoimmune diabetes. Orally administered anti-CD3 monoclonal antibody is biologically active in the gut and suppresses experimental models of autoimmune diseases. …”
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Peroxisome Proliferator-Activated Receptors and the Heart: Lessons from the Past and Future Directions by Wang-Soo Lee, Jaetaek Kim

“…Several studies have demonstrated that PPAR agonists improve dyslipidemia and glucose control in animals, supporting their potential as a promising therapeutic option to treat diabetes and dyslipidemia. However, substantial differences exist in the therapeutic or adverse effects of specific drug candidates, and clinical studies have yielded inconsistent data on their cardioprotective effects. …”
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PPARγ and Its Role in Cardiovascular Diseases by Mini Chandra, Sumitra Miriyala, Manikandan Panchatcharam

“…The activators of PPARγ are already widely used in the treatment of diabetes mellitus. The cardioprotective effect of PPARγ activation has been studied extensively over the years making them potential therapeutic targets in diseases associated with cardiovascular disorders. …”
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A Whole-Food Plant-Based Diet Reversed Angina without Medications or Procedures by Daniele Massera, Tarique Zaman, Grace E. Farren, Robert J. Ostfeld

“…Plant-based diets have been associated with improved plasma lipids, diabetes control, coronary artery disease and with a reduction in mortality. …”
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Langerhans Cell Histiocytosis Manifests with Acute Severe Hypernatremia during Hospitalization by Kullaya Takkavatakarn, Hansamon Poparn, Pisut Katavetin

“…Central diabetes insipidus (DI) is characterized by a deficiency in arginine vasopressin (AVP), an antidiuretic hormone leading to excessive free water loss in the urine and hypernatremia. …”
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Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease by G. V. Paramel, A. Sirsjö, K. Fransén

“…Several studies have been performed on the association of the genetic alterations in genes encoding NLRP3 and CARD8 with the complex diseases with inflammatory background, like inflammatory bowel disease, cardiovascular diseases, rheumatoid arthritis, and type 1 diabetes. The aim of the present review is therefore to summarize the literature regarding genetic alterations in these genes and their association with health and disease.…”
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An Unusual Case: Salmonella UTI and Orchitis in HIV Patient by Sabrina Arshed, Hongxiu Luo, John Middleton, Abdalla Yousif

“…This can lead to critical illness in those patients with immune deficiencies, especially HIV, cancer patients, and those with diabetes mellitus. However, the spread of the infection from the urinary tract to involve the testicles and epididymis is very rare. …”
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The Role of Connexin in Ophthalmic Neovascularization and the Interaction between Connexin and Proangiogenic Factors by Chuyang Xu, Hong Zhang, Wei Zhong, Hongyan Zhou

“…In ophthalmologic diseases, such as corneal new blood vessels, neonatal vascular glaucoma, and diabetes retinopathy, the formation of new blood vessels has become a critical component in patient survival. …”
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A Rare Case of Recurrent Klebsiella pneumoniae Liver Abscess by Magdelene Amoateng, Pius Osei-Bagyina, Reba Varughese, Achsah Mathew, Ishan Malhotra

“…There is high mortality with this condition, and immediate aggressive treatment is necessary. Diabetes mellitus (D.M.) is the single most important risk factor for developing KPLA. …”
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A Molecular and Clinical Review of Stem Cell Therapy in Critical Limb Ischemia by Punam P. Parikh, Zhao-Jun Liu, Omaida C. Velazquez

“…Peripheral artery disease (PAD) is one of the major vascular complications in individuals suffering from diabetes and in the elderly that can progress to critical limb ischemia (CLI), portending significant burden in terms of patient morbidity and mortality. …”
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Periferik Arter Hastalığında Yaşam Tarzı Değişikliğinin Yönetimi: Neler Yapılabilir? by Ebru Güner, Semiha Alkan Kayhan

“…Periferik damar hastalıklarında, hastalığın ilerlemesini durdurmak ve komplikasyonların önlenmesini sağlamakiçin risk faktörlerinin (sigara, hipertansiyon, diabetes mellitus gibi) kontrolü ve yaşam tarzı değişikliğinin uygulanması oldukça önemlidir. …”
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Antenatal corticosteroids in Singapore: a clinical and scientific assessment by Arundhati Gosavi, Zubair Amin, Sean William David Carter, Mahesh Arjandas Choolani, Erin Lesley Fee, Mark Amir Milad, Alan Hall Jobe, Matthew Warren Kemp

“…Approximately 9% of Singaporean babies are born preterm; the PTB rate is likely to increase given the increased use of assisted reproduction technologies, changes in the incidence of gestational diabetes/high body mass index and the ageing maternal population. …”
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