Natural History of Metabolic Dysfunction-Associated Steatotic Liver Disease: From Metabolic Syndrome to Hepatocellular Carcinoma by Melchor Alpízar Salazar, Samantha Estefanía Olguín Reyes, Andrea Medina Estévez, Julieta Alejandra Saturno Lobos, Jesús Manuel De Aldecoa Castillo, Juan Carlos Carrera Aguas, Samary Alaniz Monreal, José Antonio Navarro Rodríguez, Dulce María Fernanda Alpízar Sánchez

“…<i>Introduction</i>: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) stems from disrupted lipid metabolism in the liver, often linked to obesity, type 2 diabetes, and dyslipidemia. In Mexico, where obesity affects 36.9% of adults, MASLD prevalence has risen, especially with metabolic syndrome affecting 56.31% by 2018. …”
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A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans by Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku

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Impact of coronavirus disease 2019 on medical practice in endocrine and metabolic diseases in Japan: a nationwide surveillance study conducted by the Japan Endocrine Society by Katsunori Manaka, Sayaka Kato, Ryuichi Sakamoto, Hajime Yamakage, Tsugumi Uema, Shiori Kawai, Megumi Shibata, Izumi Hiratsuka, Sawako Nakachi, Takeshi Onoue, Takefumi Tsuchiya, Michiaki Fukui, Koshi Hashimoto, Atsushi Suzuki, Noriko Makita, Yoshihiro Ogawa, Hiroshi Arima, Noriko Satoh-Asahara, Hiroaki Masuzaki

“…Diabetes and obesity were identified as having high rates of severe cases or fatalities due to COVID-19. …”
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Post-traumatic pituitary stalk transection syndrome (PSTS) expeditiously manifested after a fall from a height combined with acute traumatic spinal cord injury: a rare case report... by Yohei Ishiki, Atsuko Tamaki, Ken-ichiro Honma, Ken Yonaha, Takamitsu Yabiku, Taiki Teruya, Moriyuki Uehara, Yoshiro Nakayama, Rei Chinen, Tsugumi Uema, Sawako Nakachi, Shiki Okamoto, Hiroaki Masuzaki

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Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

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Impact of the transition from radioimmunoassay (RIA) to chemiluminescent enzyme immunoassay (CLEIA) for the measurement of plasma aldosterone concentration (PAC) on the diagnosis o... by Ken-ichiro Honma, Yoshiro Nakayama, Atsuko Tamaki, Moriyuki Uehara, Taiki Teruya, Takamitsu Yabiku, Yohei Ishiki, Ken Yonaha, Rei Chinen, Tsugumi Uema, Shiki Okamoto, Hiroaki Masuzaki

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Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity by Kenji Hara, Atsushi Ujiie, Shiori Suzuki, Takenori Okumura, Mio Kubo, Hiroyuki Shinozaki, Mototaka Yamauchi, Takafumi Tsuchiya, Kohzo Takebayashi, Nobuyuki Shimozawa, Masafumi Koga, Koshi Hashimoto

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The challenges of using Escherichia coli as a host in recombinant insulin production by Muhammad Taher

“…Type 1 diabetes mellitus is dependent on insulin which required accessible and affordable insulin (Diabetes, 2025). …”
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Long Noncoding RNA LOC100129940-N Is Upregulated in Papillary Thyroid Cancer and Promotes the Invasion and Progression by Manting Choy, Yan Guo, Hai Li, Guohong Wei, Runyi Ye, Weiwei Liang, Haipeng Xiao, Yanbing Li, Hongyu Guan

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Gender Differences in Ghrelin Association with Cardiometabolic Risk Factors in Arab Population by Mohamed Abu-Farha, Mohammed Dehbi, Fiona Noronha, Ali Tiss, Monira Alarouj, Kazem Behbehani, Abdullah Bennakhi, Naser Elkum

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LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK by Joanna Filipowska, Zelda Cisneros, Sneha S. Varghese, Nancy Leon-Rivera, Peng Wang, Randy Kang, Geming Lu, Yate-Ching Yuan, Hung-Ping Shih, Supriyo Bhattacharya, Sangeeta Dhawan, Adolfo Garcia-Ocaña, Nagesha Guthalu Kondegowda, Rupangi C. Vasavada

“…Objective: Loss of functional β-cell mass is a major cause of diabetes. Thus, identifying regulators of β-cell health is crucial for treating this disease. …”
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A novel frameshift variant of GATA3 (p.Ala17ProfsTer178) responsible for HDR syndrome in a Japanese family by Yutaka Hasegawa, Toshie Segawa, Ai Chida, Eriko Yoshida, Hirofumi Kinno, Hiraku Chiba, Tomoyasu Oda, Yoshihiko Takahashi, Koji Nata, Yasushi Ishigaki

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Extracorporeal Cardiac Shock Wave Therapy Ameliorates Clinical Symptoms and Improves Regional Myocardial Blood Flow in a Patient with Severe Coronary Artery Disease and Refractory... by Christian Prinz, Oliver Lindner, Thomas Bitter, Detlef Hering, Wolfgang Burchert, Dieter Horstkotte, Lothar Faber

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Finger Length Ratios in Serbian Transsexuals by Svetlana Vujović, Srdjan Popović, Ljiljana Mrvošević Marojević, Miomira Ivović, Milina Tančić-Gajić, Miloš Stojanović, Ljiljana V. Marina, Marija Barać, Branko Barać, Milena Kovačević, Dragana Duišin, Jasmina Barišić, Miroslav L. Djordjević, Dragan Micić

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Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report by Alaina P. Vidmar, Linus Kaiser, Matthew J. Martin, Stuart Abel, Aimee G. Kim, Madeleine Weitzner, Cynthia E. Muñoz, Lynda K. Fisher, Mimi S. Kim, Kamran Samakar

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ARMC5 Primary Bilateral Macronodular Adrenal Hyperplasia Associated with a Meningioma: A Family Report by M. J. Ferreira, J. Pedro, D. Salazar, C. Costa, J. Aragão Rodrigues, M. M. Costa, A. Grangeia, J. L. Castedo, D. Carvalho

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Dietary fat quantity and composition influence hepatic lipid metabolism and metabolic disease risk in humans by Nikola Srnic, Felix Westcott, Eleanor Caney, Leanne Hodson

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Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis by Litong Ran, Xiufei Liu, Yongfeng Tian, Jiaran Zhu, Zhengyuan Gong, Qiao Qiao, Xin Jiang, Yuren Wang, Guojun Yang, Hongting Zheng, Yi Zheng, Hua Qu

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Composite paraganglioma-ganglioneuroma with atypical catecholamine profile and phenylethanolamine N-methyltransferase expression: a case report and literature review by Yuriko Sasaki, Maki Kanzawa, Masaaki Yamamoto, Keitaro Kanie, Hironori Bando, Kei Yoshino, Yushi Hirota, Katsumi Shigemura, Masato Fujisawa, Wataru Ogawa, Hidenori Fukuoka

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Picolinic Acid in Patients with Chronic Hepatitis C Infection: A Preliminary Report by Jolanta Zuwała-Jagiello, Monika Pazgan-Simon, Krzysztof Simon, Maria Warwas

“…The values of PA and hsCRP were more elevated in patients with diabetes than without diabetes (both P<0.01). The positive relationships were between PA and hsCRP levels (P<0.05) and the presence of diabetes (P<0.001). …”
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