A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection by Leslee N. Matheny, Sudipa Sarkar, Hanyuan Shi, Jiun-Ruey Hu, Hannah Harmsen, Ty W. Abel, Shubhada M. Jagasia, Shichun Bao

“…Work-up revealed ACTH-dependent hypercortisolemia, which did not suppress appropriately after high-dose dexamethasone. Subsequent imaging of the chest, abdomen, and pelvis did not reveal other possible ectopic sources of ACTH secretion besides the ENB. …”
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Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea by Yaşar Yildirim, Süreyya Yilmaz, Mehmet Güven, Faruk Kılınç, Ali Veysel Kara, Zülfükar Yilmaz, Gökhan Kırbaş, Alpaslan Kemal Tuzcu, Fatma Yılmaz Aydın

“…Neck and waist circumference, fasting plasma glucose, HbA1c, late-night serum cortisol, morning serum cortisol after 1 mg dexamethasone suppression test, and 24-hour urinary cortisol levels were significantly higher in OSA patients compared to control subjects. …”
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Carrageenan-induced acute inflammation in the mouse air pouch synovial model. Role of tumour necrosis factor by M. Romano, R. Faggioni, M. Sironi, S. Sacco, B. Echtenacher, E. Di Santo, M. Salmona, P. Ghezzi

“…Pretreatment with dexamethasone (DEX) or indomethacin (INDO) inhibited cell migration and reduced the concentration of TNF in the exudate. …”
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Influence of Poly(L-Lactic Acid) Nanofibers and BMP-2–Containing Poly(L-Lactic Acid) Nanofibers on Growth and Osteogenic Differentiation of Human Mesenchymal Stem Cells by Markus D. Schofer, Susanne Fuchs-Winkelmann, Christian Gräbedünkel, Christina Wack, Roland Dersch, Markus Rudisile, Joachim H. Wendorff, Andreas Greiner, Jürgen R. J. Paletta, Ulrich Boudriot

“…Although the presence of nanofibers diminished the dexamethasone-induced proliferation, there were no differences in cell densities or deposition of either COL-I or OC after 22 days of culture. …”
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A Case Report of Bowel Perforation in a Gravid COVID-19 Patient by A. T. Guiritan, J. G. Cataluña

“…Patient was eventually intubated and was given a total of two doses of tocilizumab, adequate antibiotic treatment, remdesivir, and dexamethasone. An emergency repeat cesarean section was performed due to maternal deterioration and poor variability of the fetus. …”
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Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair by Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou

“…To address the limitations associated with the off-target effects of intravenous administration and the risk of synovial cavity infection with repeated local injections, we have innovatively developed a liposomal drug depot through hyaluronic acid (HA)-modified liposomes encapsulating dexamethasone sodium phosphate (DSP)-loaded nanogels, termed HA-Lipo@G/D. …”
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Analysis of Drug Effects on Primary Human Coronary Artery Endothelial Cells Activated by Serum Amyloid A by K. Lakota, D. Hrušovar, M. Ogrič, K. Mrak-Poljšak, S. Čučnik, M. Tomšič, B. Božič, P. Žigon, S. Sodin-Semrl

“…HCAEC were preincubated for 2 h with medications from sterile ampules (dexamethasone, methotrexate, certolizumab pegol, and etanercept), dissolved in medium (captopril) or DMSO (etoricoxib, rosiglitazone, meloxicam, fluvastatin, and diclofenac). …”
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Transient Third-Degree Atrioventricular Block in a Dog with Addisonian Crisis by Paula Maria Pașca, Gheorghe Solcan, Andrei Blageanu, Caroline Maria Lăcătuș, Petru Cosmin Peștean, Constantin Adrian Stancu, Andrei Radu Baisan

“…Treatment for hyperkalemia was initiated immediately after admission, followed by dexamethasone sodium phosphate administration, which led to an improvement in the patient’s general condition, and the normalization of the ECG readings, after 24 h of therapy. …”
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The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…Despite the 41% response rate and durable responses observed with belantamab mafodotin in the Phase III confirmatory DREAMM-3 trial, the marketing license for belantamab mafodotin was later withdrawn from US and European markets when the trial did not meet its primary endpoint of superiority for progression-free survival compared with pomalidomide and dexamethasone. This review reflects on key lessons arising from the clinical journey of belantamab mafodotin in RRMM. …”
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Diagnosis of naturally‐occurring Cushing's syndrome by primary care veterinarians in selected European countries by Miguel F. Carvalho, Rodolfo O. Leal, Stefania Golinelli, Federico Fracassi, Carolina Arenas, Maria Pérez‐Alenza, Sara Galac, Carmel T. Mooney, Michael Bennaim

“…The tests most reported are the ACTH stimulation test (34.8%), low‐dose dexamethasone suppression test (LDDST; 30.4%) or a combination of different tests (25.2%). …”
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The Combined Use of Platelet-Rich Plasma Clot Releasate and Allogeneic Human Umbilical Cord Mesenchymal Stem Cells Rescue Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Yanxue Wang, Shuo Luan, Ze Yuan, Shaoling Wang, Shengnuo Fan, Chao Ma, Shaoling Wu

“…To evaluate the combinatorial therapeutic effects of platelet-rich plasma clot releasate (PRCR) and umbilical cord mesenchymal stem cells (UC-MSCs) on glucocorticoid-induced ONFH, a dexamethasone (DEX)-treated cell model and a high-dose methylprednisolone (MPS)-treated rat model were established. …”
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Synthesis and pharmacological properties of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione by Alexander A. Ozerov, Daria V. Merezhkina, Natalia A. Gurova, Lyudmila V. Naumenko, Denis A. Babkov, Victor S. Sirotenko, Roman A. Litvinov, Alena S. Taran, Nadezhda V. Stepanova, Umida M. Ibragimova, Alexander A. Spasov, Vadim A. Kosolapov

“…This article presents data on the synthesis and pharmacological activity studies of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione 6-11 and reference drugs amiloride, rimeporide, zoniporide, dexamethasone, aminoguanidine, and acetylsalicylic acid. …”
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Effect of Lumbar Epidural Steroid Injections on Osteoporotic Fracture and Bone Mineral Density in Elderly Women with Diabetes Mellitus by Minsoo Kim, Jiwon Bak, Sejin Kim, Hee-Jeong Son, Seong-Sik Kang, Jin Hue, Byeongmun Hwang, Seung Koo Lee

“…The mean total number of ESIs was 3.4 and 3.2, and the mean cumulative administered dose of glucocorticoids (dexamethasone) was 17 and 16 mg in the non-DM and DM groups, respectively. …”
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Synergistic Activations of REG Iα and REG Iβ Promoters by IL-6 and Glucocorticoids through JAK/STAT Pathway in Human Pancreatic β Cells by Akiyo Yamauchi, Asako Itaya-Hironaka, Sumiyo Sakuramoto-Tsuchida, Maiko Takeda, Kiyomi Yoshimoto, Tomoko Miyaoka, Takanori Fujimura, Hiroki Tsujinaka, Chikatsugu Tsuchida, Hiroyo Ota, Shin Takasawa

“…In this study, we found that combined addition of IL-6 and dexamethasone (Dx) induced REG Iα and REG Iβ expression in human 1.1B4 β cells. …”
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Enhancing the Solubility of Co-Formulated Hydrophobic Drugs by Incorporating Functionalized Nano-Structured Poly Lactic-<i>co</i>-glycolic Acid (<i>nf</i>PLGA) During Co-Precipitat... by Mohammad Saiful Islam, Somenath Mitra

“…This study explores a co-precipitation method to prepare co-formulated crystals of griseofulvin (GF) and dexamethasone (DXM), utilizing nanostructured, functionalized polylactic glycolic acid (<i>nf</i>PLGA) as a solubility enhancer. …”
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Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids by E. V. Sukhareva, T. S. Kalinina, V. V. Bulygina, N. N. Dygalo

“…Administration of hydrocortisone or dexamethasone to female rats on day 20 of pregnancy and to 3-day-old neonatal pups significantly increased TH mRNA levels (real-time PCR) and enzyme activity as well as protein levels determined by ICH in the locus coeruleus. …”
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In Vitro Free Radical Scavenging Properties and Anti-Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of... by Ingrid Vicente Farias, Eduarda Fratoni, Lais Cristina Theindl, Angela Machado de Campos, Eduardo Monguilhott Dalmarco, Flavio Henrique Reginatto

“…Regarding the chemical markers, all compounds showed strong inhibition of NOx secretion, especially theobromine, which was 200x more potent than dexamethasone. Furthermore, TNF-α secretion was also significantly decreased by THEO at 0.033 μM (22.15±6.49%), NCA at 1.97 μM (27.46±3.98%), CCA at 0.35 μM (39.76±5.73%), CGA at 0.56 μM (23.58±5.79%), CAF at 0.52 μM (26.45±5.34%), and RUT at 0.16 μM (40.18±3.70%). …”
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Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-M... by Jingjing Chen, Wenxiao Qiao, Xiaoming Xue, Dian Li, Ye Zhang, Di Xie, Jinyun Wang, Yaoqin Sun, Shuo Yang, Zhuomin Yang

“…The control group and the SQHT groups were treated with dexamethasone and SQHT by gavage, respectively. After treatment, superoxide dismutase (SOD) serum levels, total antioxidant capacity (TAOC), lipid peroxidation, and malondialdehyde (MDA) were detected by enzyme-linked immunosorbent assay (ELISA). …”
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Protective effects and antioxidant mechanisms of lactobacillus combined with carnosine on the stomach and small intestine by Jian Qin, Ziyi Luo, Xu Yang, Yunqing Zhang, Huiying Li, Conghui Wang, Zhiqiang Zou, Yue Ma, Jing Ma, Daoyou Yue, Dipeng Zhao, Sen Qin, Rong Du

“…Here, we report the protective effects of LAB and/or CAR on the gastrointestinal tissues in normal or dexamethasone (Dex)-induced stress mice. The combination of LAB and CAR protected the structures of stomach and small intestine, alleviating the Dex-induced tissue damages. …”
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Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells by Morten Juhl, Bjarke Follin, Monika Gad, Jesper Larsen, Jens Kastrup, Annette Ekblond

“…Dendritic cells were cocultured with different ratios of ASC and matured with LPS and IFN-γ. Dexamethasone was included as an immunosuppressive control. …”
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