Aging-enhanced autophagy activity promotes fibrotic progression via the TGF-β2/Smad signaling pathway in trabecular meshwork cells—a new insight from POAG by Jin Han, Jun Wang, Ling Shen, Yiting Cai, Xuze Wang, Ailixiati Wumaier, Wei Chen, Wei Han

“…Additionally, we used dexamethasone-treated TM cells as a POAG model to explore the role of autophagy in fibrotic progression. …”
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Epidural Brain Metastases in a Patient with Early Onset Pancreatic Cancer: A Case Report and Literature Review by Aibek E. Mirrakhimov, Farah N. Khan

“…The patient was started on ondansentron, metoclopramide, and dexamethasone. The cranial irradiation was started, and the patient’s headache and nausea significantly improved. …”
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Pneumoperitoneum without Intestinal Perforation in a Neonate: Case Report and Literature Review by Prabhavathi Gummalla, Gratias Mundakel, Maksim Agaronov, Haesoon Lee

“…He was treated with dexamethasone to wean from the ventilator. Pneumoperitoneum developed in association with left sided pneumothorax following mechanical ventilation and cardiopulmonary resuscitation. …”
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Opioid Sparing Analgesics in Spine Surgery by Logan A. Reed, Mihir Patel, Kevin Luque, Steven M. Theiss

“…These opioid alternatives include acetaminophen, NSAIDs, COX-2 specific inhibitors, gabapentinoids, local anesthetics, dexamethasone, and ketamine. Each of these drugs presents its own advantages and disadvantages which can make it difficult to implement universally. …”
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Role of Apolipoprotein E in Anxiety by Jacob Raber

“…ApoE4, but not mice lacking apoE, or apoE3 mice showed impaired dexamethasone suppression of plasma corticosterone. Understanding how apoE modulates measures of anxiety might help the developments of therapeutic targets to reduce or even prevent measures of anxiety in health and in dementing illnesses.…”
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“A Dangerous Black Box:” Idiopathic Hemophagocytic Lymphohistiocytosis in Adult Patients—A Case Report and Review of the Literature by Nada Agbariah, Javier Sanz, Alicia Rovó

“…An early intervention first with dexamethasone and later with cyclosporine was performed. …”
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Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis by Lauren Tada, Humayun Anjum, W. Kenneth Linville, Salim Surani

“…The optimal treatment for recurrent pleural effusions in amyloidosis has not been determined; however, our patient responded to therapy with Cyclophosphamide-Bortezomib- (Velcade-) Dexamethasone (CyBorD) and had no repeat hospitalizations or recurrence of pleural effusion at four-month follow-up after initiation of therapy.…”
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A Rare Cause of Hemophagocytic Lymphohistiocytosis: Fusobacterium Infection—A Case Report and Review of the Literature by Ghulam Rehman Mohyuddin, Heather J. Male

“…Given continued fevers despite appropriate antimicrobials, a bone marrow biopsy was performed revealing increased histiocytes with hemophagocytosis. Dexamethasone was added with dramatic clinical improvement. …”
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细胞凋亡与腭裂发生关系的实验研究 by 黄洪章, 陈亦阳

“…【目的】探讨由地塞米松(dexamethasone , DEX)诱导的腭裂胚胎模型的腭裂形成中细胞凋亡的意义与作用。【方 法】给12 孕期日(g estation day , GD)的昆明小白鼠腹腔注射10～ 50 mg/ kg 剂量的DEX , 获取腭裂胚胎模型。…”
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Comparative Effects of Sulforaphane and Allyl Isothiocyanate on 3T3-L1 Adipogenesis by Satoru Sakuma, Kana Yasuda, Risa Kitahara, Kaho Tsujimoto, Kishiko Yamashita, Naohiro Hoshino, Yohko Fujimoto, Keiichiro Okuhira

“…A mixture of insulin, dexamethasone, and 3-isobutyl-1-methylxanthine was used to establish a differentiation medium. …”
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Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis by Ivan Keogh, Rohana O’Connell, Sean Hynes, John Lang

“…Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient’s postoperative period was uneventful and had remained disease free for 1 year. …”
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Cerebrovascular Complications in Bacterial Meningitis by Shahrzad S. Deliran, Matthijs C. Brouwer, Diederik van de Beek

“…Cerebrovascular complications are important predictors of unfavorable outcome and death, and the use of adjunctive dexamethasone has been described to reduce the incidence. …”
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Secondary Hemophagocytic Lymphohistiocytosis: A Challenging Diagnosis in a Patient with Autoimmune Hepatitis by Colin Casault, Juan G. Posadas-Calleja

“…He was treated with dexamethasone and etoposide, without bone marrow transplantation (BMT) due to poor functional status. …”
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Inhibition of the production of mediators of inflammation by corticosteroids is a glucocorticoid receptor-mediated process by G. S. Madretsma, A. P. M. van Dijk, C. J. A. M. Tak, J. H. P. Wilson, F. J. Zijlstra

“…In order to find an explanation for corticosteroid resistance we assessed whether inhibition by dexamethasone (DEX) of the stimulated production of TNF-∝, IL-6, PGE2 and LTB4 by peripheral blood mononuclear cells (MNC) depends on binding to the glucocorticoid receptor (GR), and whether it is determined by the number or the affinity of the GR of these cells. …”
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Sintilimab for the treatment of lung adenocarcinoma-induced immune-related hypophysitis: a case report by Ming-xing Wang, Ai-xin Liu, Qing-ming Sun, Wan-hui Dong

“…The patient experienced symptomatic relief following pulse therapy with dexamethasone sodium phosphate injections (30mg every 12 hours), and was subsequently treated with prednisone acetate tablets (30 mg/day), which were gradually reduced to a physiological replacement dose. …”
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Involvement of serotonin and eicosanoids in the rat paw oedema response to the essential oil of Pilocarpus spicatus by J. C. R. Silva, V. S. N. Rao

“…The oedemagenic activity of PSEO was also suppressed by pretreating the rats with the eicosanoid synthesis inhibitors, phenylbutazone, EP 10161 and dexamethasone. This last drug showed the greatest potency. …”
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A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM) by Sze-Ting Bong, Lydia Ngiik-Shiew Law, Jodi Woan-Fei Law

“…To date, clinical trials of ibrutinib as therapeutic alternative for MM have produced promising results, particularly as combination therapy with other agents such as dexamethasone and carfilzomib. However, there is limited evidence on the Btk mechanisms involved in MM, hence, it is important to further investigate the Btk oncogenic signalling pathway(s) in MM cells in order to establish successful and improved treatment of MM. …”
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鼻咽癌细胞的糖皮质激素受体含量及受新酮醛的影响

“…以~H-地塞米松(~3H-dexamethasone,~3H-Dex)为放射配基,测定鼻咽癌细胞糖皮质激素受体(GCR)含量,结果当用地塞米松(Dex)非标记配基作竞争性试验时,GCR水平较高,而且低分化鼻咽癌上皮细胞(CNE-Ⅱ)GCR含量明显高于高分化细胞(CNE-I)(P<0.05);用新酮醛、新鱼腥草素或多糖替换Dex作竞争物时,CNE-Ⅰ细胞由于受新酮醛作用影响,GCR含量明显高于Dex作用时的含量(P<0.05);CNE-Ⅱ细胞GCR含量提示新酮醛、新鱼腥草素、Dex三者的作用大致相同(P>0.05)。…”
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The Effects of Circadian Rhythm on Lead-Induced Toxicity in the DBC1.2 Olfactory Dark Basal Cell Line by Teru Kamogashira, Shu Kikuta, Tatsuya Yamasoba

“…Methods: The DBC1.2 olfactory dark basal cell line was used. Dexamethasone shock was used to reset the circadian clock 24 h (Group 1) and 36 h (Group 2) after seeding. …”
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Adrenal Incidentalomas with Supraphysiologic Response to ACTH Stimulus: A Case Report by Marianna Antonopoulou, Asya Perelstein

“…Subsequently, the patient underwent screening for Cushing's syndrome (CS) with a dexamethasone suppression test. Patient failed the suppresion test, raising the issue for subclinical CS (SCS), likely due to ACTH-independent macronodular adrenal hyperplasia. …”
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