Structural tailoring of etoricoxib: A spectrochemical, medicinal and pharmacological study by Bakul Akter, Silvia Aishee, Abdullah Hridoy, Md. Mehedi Hasan Pulok, Mohammad Ariful Islam, Antu Biswas, Aurna Patwary, Majedul Hoque, MD. Sazidul Islam, Md. Nipatul Hasan Nirob, Faisal Islam Chowdhury, Monir Uzzaman

“…A total of 21 derivatives were designed by introducing various functioning sets at the R3, R2, and R1 sites of ETC. …”
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Process-based VOCs Source Profiles and Contributions to Ozone Formation in Typical Organic Solvent-used Industries in Hangzhou by Zhinian Li, Wenjuan Li, Rong Zhou, Xiaoping Miao, Jianhai Lu, Zhongren Wang, Zhongping Yang, Jian Wu

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p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity by Rui Ding, Tiffany C. Edwards, Prithwish Goswami, Daniel J. Wilson, Christine D. Dreis, Yihong Ye, Robert J. Geraghty, Liqiang Chen

“…Recently, p97 has emerged as an important pro-viral host factor and p97 inhibitors are being evaluated as potential antiviral agents. <b>Methods:</b> We designed and synthesized novel p97 inhibitors based on the rearrangement of the central fused ring of our previously reported p97 inhibitors. …”
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Exploring Optimisation Pathways for Underground Space Quality Under the Synergy of Multidimensional Perception and Environmental Parameters by Tianning Yao, Liang Sun, Lin Geng, Yao Xu, Ziqi Xu, Kuntao Hu, Xing Chen, Pan Liao, Jin Wang

“…This study provided quantitative design benchmarks for underground spaces’ dynamic regulation and sustainable management, proposing a precise and adaptive environmental decision-making framework that combines physical parameters with user-perception feedback.…”
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Topotypes : le projet de paysage comme démarche de recherche by Thierry Kandjee, Sébastien Penfornis

“…Experimental, Reflective and critical Design practice. From garden to large scale strategy, projects and design studios as investigations, experiments, procedures are developed. …”
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Leakage Performance of the GM + CCL Liner System for the MSW Landfill by Fan Jingjing

“…It is concluded that the liner system designed according to the minimum design requirements of Germany provide the best antileakage performance, while that of Japan performs the lowest. …”
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Numerical Modeling and Dynamic and Static Performance Analysis of Hydraulic Mounting by Ti Wu, Penghui Xu, Jianghua Fu, Jintao Su

“…The basic parameters affecting the installation design are obtained. It provides some theoretical basis and parameter verification for hydraulic bushing design. …”
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Systems Engineering in Terms of Exergy by José A. Camberos, David J. Moorhouse

“…We address the design of a flight vehicle from the viewpoint of a system of systems and we discuss the integration of the individual technical disciplines. …”
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Towards a Fluid Planning Approach in Germany: An Option for Social Fragmentation? by Maram Tawil, Christa Reicher, Eva Krings, Mehmet Haydan, Raveena Gadkar, Alena Gavrilova, Ursula Cardenas Vignes

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Balancing Requirement Statements, Features and Technology Development Using QFD in Indigenous Macro Products in the Aviation Industry by Mahdi Googerdchian, Mohsen Asadi, Seyed ziaodin Ghazizadeh Fard, Soheil Imamian

“…Purpose: This study aims to create and develop an approach for the design and gradual delivery of the product in the shortest time and through the balance of the elements of technological readiness, the need statement document, and the characteristics of the product in large and complex air systems.Design/methodology/approach: In this study, the balancing process has been carried out using three stages of the Quality Function Deployment (QFD). …”
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Research progress of powder metallurgical nano-particulate reinforced titanium matrix composites by LI Shaopeng, SUI Xiaodong, WANG Meiqi, XIAO Shan, HAN Yuanfei, WANG Xiangming

“…The development directions of future research focus on:（1）interface reaction control and thermal stability design；（2）batch production and low-cost preparation technology；（3）research on special thermal deformation and heat treatment process；（4）tissue configuration design and toughness mechanism and （5）other key mechanical properties research of nano-particulate reinforced TMCs.…”
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Impact of Coastal Squeeze Induced by Erosion and Land Reclamation on Salt Marsh Wetlands by Guangzhi Zhang, Jiali Gu, Hao Hu, Maoming Sun, Jie Shao, Weiliang Dong, Liang Liang, Jian Zeng

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Annotation of Software Requirements Specification (SRS), Extractions of Nonfunctional Requirements, and Measurement of Their Tradeoff by Muhammad Asif, Ishfaq Ali, Muhamad Sheraz Arshed Malik, Muhammad Hasanain Chaudary, Shahzadi Tayyaba, Muhammad Tariq Mahmood

“…So, an optimum tradeoff among these design problem within a module is required to have better design decisions. …”
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Stability Optimization of a Disc Brake System with Hybrid Uncertainties for Squeal Reduction by Hui Lü, Dejie Yu

“…Based on the hybrid uncertain model, the reliability-based design optimization (RBDO) of a disc brake with hybrid uncertainties is proposed to explore the optimal design for squeal reduction. …”
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Research and Analysis on Assembly Methodology for the Fusion Blanket System by Ruonan Zhang, Jiazhu Li, Shuling Xu, Qigang Wu, Dawei Yu, Qiankun Man

“…In the development process of the blanket system, assembly design is quite important, and suitable systematic methodologies are required. …”
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SENSATION ON FEET COOLING WITH THERMAL COMFORT IN A PORUS WALLED ROOM by A. A. Ayu Oka Saraswati, Cornelia Hildegardis, Ida Bagus Gde Primayatna

“…Comfort for users is the goal of a arsitectural design. This study aims to propose a new innovations in the meeting room consept design with cases in the Faculty of Engineering meeting room, Udayana University in Jimbaran – Bali. …”
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Highly Efficient and achromatic mid-infrared silicon nitride meta-lenses by Abdullah Maher, Mohamed A. Swillam

“…Abstract Inverse design with topology optimization considers a promising methodology for discovering new optimized photonic structure that enables to break the limitations of the forward or the traditional design especially for the meta-structure. …”
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Computer Deep Learning Network Security Vulnerability Detection Based on Virtual Reality Technology by Xiaokun Zheng

“…The design of the system has achieved the expected design goal. …”
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Dynamic Analysis and Fabrication of Single Screw Conveyor Machine by Sundarraj Moorthi, Meikandan Megaraj, Lenin Nagarajan, Alagar Karthick, Murugesan Bharani, Pravin P. Patil

“…The design and development of machine tools play a vital role in the current economic growth. …”
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Rétroaction dans les processus numériques de conception by Sébastien Bourbonnais

“…The goal is to show that the knowledge embedded by the various computer programs will have led to a real overhaul of design knowledge, as part of the implementation of a new epistemology, driven by digital design processes.…”
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