Investigating the Efficacy of the Web-Based Common Elements Toolbox (COMET) Single-Session Interventions in Improving UK University Student Well-Being: Randomized Controlled Trial by Jeffrey Lambert, Maria Loades, Noah Marshall, Nina Higson-Sweeney, Stella Chan, Arif Mahmud, Victoria Pile, Ananya Maity, Helena Adam, Beatrice Sung, Melanie Luximon, Keren MacLennan, Clio Berry, Paul Chadwick

“…Single-session interventions (SSIs) are designed to be scalable and accessible, delivering core evidence-based intervention components within a one-off encounter. …”
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Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against <i>Aspergillus</i> Species by Tatevik Sargsyan, Lala Stepanyan, Henrik Panosyan, Heghine Hakobyan, Monika Israyelyan, Avetis Tsaturyan, Nelli Hovhannisyan, Caterina Vicidomini, Anna Mkrtchyan, Ashot Saghyan, Giovanni N. Roviello

“…This study focuses on the synthesis and antifungal evaluation of novel 9-fluorenylmethoxycarbonyl (Fmoc)-protected 1,2,4-triazolyl-α-amino acids and their dipeptides, designed to combat fungal pathogens. More in detail, we evaluated their antifungal activity against various species, including <i>Aspergillus versicolor</i> (ATCC 12134) and <i>Aspergillus flavus</i> (ATCC 10567). …”
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Reims antique, acquis et perspectives by Magalie Cavé, Philippe Rollet, Régis Bontrond

“…This article adopts an approach designed to assess the current state of acquired knowledge and developed hypotheses relative to the spatial organization of the city, enriching both with the most recent research developments. …”
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Disturbances of visual perception in non-demented patients with Parkinson’s disease by R. Timofejavaitė, V. Vilda, A. Liveikienė, R. Kaladytė-Lokominienė

“…All participants were evaluated by means of a specially designed questionnaire on disturbances of visual perception, Montreal Cognitive Assessment (MoCA), and Hospital Anxiety and Depression scale (HAD). …”
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Fracture-seepage characteristic zones of the overburden of extra-thick coal seams: Evolutionary patterns and their engineering applications by Xiangguo KONG, Tianshuo ZHAO, Haifei LIN, Pengxiang ZHAO, Xu WANG, Yuchu CAI, Pengfei JI, Di HE, Ke LI, Chuanyu XU

“…The analysis of the evolution model reveals that the medium-elevation transition zone and the high-elevation constant current zone were the dominant horizons for gas extraction, with the vertical distances of boreholes designed ranging from 6 m to 25 m. The changes in the pure gas flow extracted from boreholes can be divided into three stages: the initial fluctuation, rapid growth, and slow drop stages. …”
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Global biogeography of N₂-fixing microbes: <i>nifH</i> amplicon database and analytics workflow by M. Morando, J. D. Magasin, S. Cheung, S. Cheung, M. M. Mills, J. P. Zehr, K. A. Turk-Kubo

“…To address these knowledge gaps, a bioinformatic workflow was designed that standardizes the processing of <i>nifH</i> amplicon datasets originating from high-throughput sequencing (HTS). …”
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Production performance of indonesian eel Anguilla bicolor bicolor with the addition of calcium carbonate (CaCO3) in to the culture media by Andre Rachmat Scabra, Tatag Budiardi, Daniel Djokosetiyanto

“…ABSTRACT   This study aimed to determine effect of calcium carbonate (CaCO3) addition in to the culture media for the production performance (survival rate, biomass growth rate, food conversion ratio, and coefficient of diversity) of Indonesian eel Anguilla bicolor bicolor. The experimental designed CRD with four treatments (calcium carbonate addition with dose A, 0 mg/L; B, 50 mg/L;  C, 100 mg/L; and D, 150 mg/L) and three replications. …”
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The Inventory of the Estate farm Senkoniai by Stasys Pamerneckis, Roberta Sakalauskaitė

“…Part of the land was designated for gardening and hop growing. The arable land, belonging both to the estate and to the peasants, was sectioned according to the traditional three-field system. …”
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Investigation of the effect of intravitreal bevacizumab treatment on left heart function using speckle tracking echocardiography by Mehmet Şahinbaş, İdris Buğra Çerik, Duygu Yalınbaş Yeter

“…Methods: In this prospectively designed study, 44 patients who were going to start intravitreal anti-VEGF treatment were included in the study. …”
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Effect of an Internet-Based Pilates Telerehabilitation Intervention in People With Multiple Sclerosis: Protocol for a Randomized Controlled Trial by Andrea Tacchino, Michela Ponzio, Paolo Confalonieri, Letizia Leocani, Matilde Inglese, Diego Centonze, Eleonora Cocco, Paolo Gallo, Damiano Paolicelli, Marco Rovaris, Loredana Sabattini, Gioacchino Tedeschi, Luca Prosperini, Francesco Patti, Edoardo Sessa, Elisabetta Pedrazzoli, Mario Alberto Battaglia, Giampaolo Brichetto

“…The primary outcome is the Timed Up and Go, a test designed to assess walking. We will also administer additional tests for motor function (visual analog scale 0-10, Timed 25-Foot Walk, Ambulation Index, 2-minute walk test, Twelve Item Multiple Sclerosis Walking Scale, Nine-Hole Peg Test), cognition (Brief International Cognitive Assessment for Multiple Sclerosis), fatigue (Modified Fatigue Impact Scale), quality of life (Multiple Sclerosis Quality of Life-54), well-being (Psychological Well-Being Scales), and PA (International Physical Activity Questionnaire and Minnesota Leisure Time Physical Activity Questionnaire). …”
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Population structure, floral diversity, habitat geography, and conservation status of Himalayan horse chestnut (Aesculus indica) in western Himalayan moist temperate forest ecosyst... by Urwa Irfan, Hamayun Shaheen, Muhammad Manzoor, Muhammad Manzoor, Sidra Nasar, Raja Waqar Ahmed Khan, Syed Waseem Gillani, Syed Waseem Gillani, Abdulwahed Fahad Alrefaei, Arbaz Attique, Asif Kamal, Sarah Abdul Razak, Malik Talha Riaz

“…This study provides a comprehensive assessment of the population structure, floral diversity, habitat geography, phytosociology, threats, and conservation status of Aesculus indica in the western Himalayan region of Kashmir. This study was designed to investigate distribution patterns, community structure, floristic diversity, and phytosociological attributes of A. indica forests, as well as evaluate the habitat geography of species by using GIS analysis. …”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…On the other hand, VOSviewer is designed to construct various types of bibliometric networks and is characterized by its intuitive and user-friendly interface. …”
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Development and validation of a prediction model for coronary heart disease risk in depressed patients aged 20 years and older using machine learning algorithms by Yicheng Wang, Yicheng Wang, Yicheng Wang, Chuan-Yang Wu, Hui-Xian Fu, Jian-Cheng Zhang, Jian-Cheng Zhang, Jian-Cheng Zhang

“…Currently, there is no predictive model specifically designed to evaluate the risk of coronary heart disease among individuals with depression. …”
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The fibrosis-4 index and its association with carotid atherosclerosis in type 2 diabetes: a cross-sectional study in China by Ying Miao, Yu Wang, Qin Wan, Nanwei Tong

“…While liver fibrosis scores were originally designed for application in individuals with liver steatosis, an increasing number of studies have shown that they are also associated with cardiovascular disease risk. …”
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Etelcalcetide: What we know eight years since its approval by Pedro Freitas, Luciano Pereira

“…There is a lack of studies specifically designed to evaluate its role in reducing fractures, CV and all-cause mortality. …”
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Assessment of hemodynamic disturbances and impaired ventricular filling in asymptomatic fontan patients: A 4D flow CMR study by Li-Wei Hu, Xiaodan Zhao, Shuang Leng, RongZhen Ouyang, Qian Wang, Ai-Min Sun, Yi-Man Liu, Wei Dong, Liang Zhong, Yu-Min Zhong

“…Background: The Fontan procedure is a surgical intervention designed for patients with single ventricle physiology, wherein the systemic venous return is redirected into the pulmonary circulation, thereby facilitating passive pulmonary blood flow without the assistance of ventricular propulsion. …”
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A novel ddPCR™ assay for eDNA detection and quantification of Greater Amberjack Seriola dumerilli and three congeners in US waters: challenges and application to fisheries independ... by P. Joana Dias, Ryan Lehman, Bryan L. Huerta-Beltrán, Ana Wheeler, Crystal L. Hightower, Jessica Heise, Theodore Switzer, Clint Rhode, J. Marcus Drymon, Lynne Stokes, Mark A. Albins, Sean Powers, Nicole Phillips

“…Time-series data from a carefully designed eDNA survey, that estimates relative abundance, could be used as an index of relative abundance for the S. dumerili stock assessment. …”
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Advancing poliovirus eradication: lessons learned from piloting direct molecular detection of polioviruses in high-risk and priority geographies by Paula L. Marcet, Brandon Short, Ashley Deas, Hong Sun, Chelsea Harrington, Shahzad Shaukat, Muhammad Masroor Alam, Marycelin Baba, Adedayo Faneye, Prossy Namuwulya, Lea Necitas Apostol, Tamer Elshaarawy, John Kofi Odoom, Peter Borus, Shelina Moonsamy, Yogolelo Riziki, Marie Claire Endegue Zanga, Mesfin Tefera, Anfumbom K. W. Kfutwah, Salmaan Sharif, Varja Grabovac, Cara C. Burns, Nancy Gerloff

“…This work summarizes the results of a multi-laboratory evaluation designed to field-test the performance and applicability of a molecular Direct Detection strategy (DD-ITD) that does not require amplification of live poliovirus. …”
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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

“…Epithelial membrane protein-2 (EMP2) is highly expressed in invasive breast cancer (BC), including triple-negative BC (TNBC), and represents an attractive therapeutic target.Methods We designed a novel fusion protein (GrB-Fc-KS49) composed of an active GrB fused to an anti-EMP2 single-chain antibody tethered through the immunoglobulin G heavy chain (Fc) domain. …”
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An observational study evaluating the epidemiological and entomological impacts of piperonyl butoxide insecticide-treated nets (ITNs) compared to a combination of indoor residual s... by Banchamlak Tegegne, Delenasaw Yewhalaw, Emily R Hilton, Sarah Zohdy, Cecilia Flatley, Kelly M Davis, Amha Worku, Meshesha Balkew, Peter Mumba, Sheleme Chibsa, Jon Eric Tongren, Gudissa Assefa, Achamyelesh Sisay, Dawit Teshome, Mastewal Worku, Mulat Yimer, Melissa Yoshimizu, Isabel Swamidoss, Carla Mapp, Jimee Hwang, Wendy Inouye, Aklilu Seyoum, Dereje Dengela, Sarah M Burnett

“…This study assesses the epidemiological and entomological impacts of piperonyl butoxide insecticide-treated nets (PBO ITN-only arm) compared with the combination of two annual non-pyrethroid indoor residual spraying (IRS) campaigns and standard pyrethroid ITNs (IRS+Standard Pyrethroid ITN arm) in the Amhara region of Ethiopia.Methods An open-label, stratified block-cluster randomised trial was designed to compare the impacts of the two intervention arms. …”
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