Business targeting in Iran: a hybrid simulation-optimization approach by amir mansour tehranchian, Sogand Hoseinnia Chafjiri

“…In the country of Iran, a 10-year strategy for the period of 2021-2031 has been designed and implemented so that people with different degrees of desirability are employed. …”
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circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes by Kai Yuan Ji, Xue Qing Zhang, Yi Wei Zhao, Chun E Liang, Xin Yuan, Yun Hai Zhang

“…The circRNA18 interference vector was designed and synthesized to transfect melanocytes and detect the effect of circRNA18 interference on melanin production. …”
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Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…Our primary innovation lies in developing an arbitrary user-pairing strategy for NOMA-based systems to secure short-packet delivery for IoT applications by jointly designing the power allocation policy and RIS’s phase shifter. …”
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Efficient Hydrolysis of Sugar Beet Pulp Using Novel Enzyme Complexes by Maria I. Komarova, Margarita V. Semenova, Pavel V. Volkov, Igor A. Shashkov, Alexandra M. Rozhkova, Ivan N. Zorov, Sergei A. Kurzeev, Aidar D. Satrutdinov, Ekaterina A. Rubtsova, Arkady P. Sinitsyn

“…The current study was designed with a primary objective that focused on the development of a strain that had the potential for enhanced productivity and the capacity to produce enzymes suitable for beet pulp hydrolysis. …”
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Shared prognostic information in amyotrophic lateral sclerosis – systematic assessment of the patients’ perception of neurofilament light chain and the ALS functional rating scale... by Lukas Maximilian Möhwald, André Maier, Torsten Grehl, Ute Weyen, Patrick Weydt, René Günther, Paul Lingor, Bettina Göricke, Susanne Petri, Julian Grosskreutz, Matthias Boentert, Isabell Cordts, Jochen H. Weishaupt, Johannes Dorst, Christoph Münch, Thomas Meyer, Petra Baum

“…Methods In a multicenter study, 149 ALS patients were assessed for their perception of shared information about NfL and ALSFRS-R using an investigator-designed survey and established questionnaires. The recommendation of NfL and ALSFRS-R to fellow patients was assessed using the Net Promoter Score (NPS). …”
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Knowledge, attitudes, and practices among physicians and pharmacists toward antibiotic use in sepsis by Jingmin Zhang, Jingmin Zhang, Haipeng Shi, Haipeng Shi, Yanmei Xia, Yanmei Xia, Zhenghua Zhu, Yaojun Zhang

“…This study aimed to assess the knowledge, attitudes and practices (KAP) among physicians and pharmacists toward antibiotic use in sepsis.MethodsThis web-based cross-sectional study was conducted at Shanxi Bethune Hospital between June 2023 and October 2023. A self-designed questionnaire was developed to collect demographic information of physicians and pharmacists, and to assess their knowledge, attitudes and practices toward antibiotic use in sepsis.ResultsA total of 200 valid questionnaires were collected. …”
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In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey IκBα-siRNA by Zhaoxing Ou, Rui Zeng, Yifan Lin, Si Zhang, Mohammad Alzogool, Peng Zeng, Yuqing Lan

“…Three IκBα-specific double-stranded siRNAs were designed and synthesized. They were transfected into primarily cultured cynomolgus monkey CM cells and TM cells. …”
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Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies by B. Dumont, C. Barlagne, P. Cassart, J.E. Duval, A. Fanchone, J-L. Gourdine, O. Huguenin-Elie, Y. Kazakova, J. Klötzli, A. Lüscher, E. Oteros-Rozas, D. Pomies, M.G. Rivera Ferre, W.A.H. Rossing, V. Stefanova, A. Swartebroeckx, C. Zagaria

“…Long-term commitment from local practitioners is required so that co-designed solutions are implemented, which can strengthen the economic and social viability of animal production areas.…”
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FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

“…The present study was designed to determine whether FAM134B is expressed in SGNs of C57BL/6 mice and, if so, to explore the potential function of FAM134B in Cis-induced SGN damage in vitro.MethodsMiddle turns of neonatal murine cochleae were cultured and treated with 30 μM Cis in vitro. …”
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Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury by Chenyang Li, Chenyang Li, Yuchen Xu, Tao Feng, Tao Feng, Minmin Wang, Minmin Wang, Minmin Wang, Xiaomei Zhang, Li Zhang, Li Zhang, Ruidong Cheng, Weihai Chen, Weihai Chen, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang

“…Pairwise spatial filters were then designed to extract discriminative spatial network topologies. …”
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A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial by Colleen Stiles-Shields, Karen M. Reyes, Tanvi Lakhtakia, Shannon R. Smith, Olga E. Barnas, Elizabeth L. Gray, Charles J. Krause, Kaylee P. Kruzan, Mary J. Kwasny, Zara Mir, Sameer Panjwani, Steven K. Rothschild, Lisa Sánchez-Johnsen, Nathan W. Winquist, Emily G. Lattie, Nicholas B. Allen, Madhu Reddy, David C. Mohr

“….), informed by behavioral activation and using passive sensing technology to provide behavioral “insights” and target behaviors associated with mental health symptoms, alongside lay-provider coaching, or (2) Control: the Mood Education mobile app (ME), containing static psychoeducational resources designed to target mental health symptoms. Both apps collected usage data. …”
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The Chinese version of the immediate mood scaler (IMS): a study evaluating its validity, reliability, and responsiveness in patients with MDD in China by Xiongying Chen, Zizhao Feng, Nanxi Li, Le Xiao, Xu Chen, Xuequan Zhu

“…However, most conventionally used assessment tools for MDD symptoms are not designed for real-time assessment. The Immediate Mood Scaler (IMS) is suitable for the real-time evaluation of the mood of patients with MDD. …”
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Reflecting on the impact of the COVID pandemic on patient management and its subsequent influence on long-term outcomes: a case–control study in the field of esophago-gastric cance... by Mohamed Alasmar, Nadia Matias, Norah Ali M. Alhamed, Omneya Alwani, Brogan Rudge, Terngu David Moti, Muhammad Ossama Yassin Abdelwahab, Jennifer Stockton, Charef Raslan, Jess Cairney-Hill, Mohammad Altarawni, Bilal Alkhaffaf, on behalf Greater Manchester Oesophago-Gastric Service

“…Methods A retrospective cohort study was designed comparing three patient groups of those referred to EG MDT in the same 6-month period pre-pandemic (PP;2019) during the initial phase of the pandemic (P1;2020) and the year after the initial phase (P2;2021). …”
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Ion homeostasis and coordinated salt tolerance mechanisms in a barley (Hordeum vulgare L.)doubled haploid line by Hongwei Xu, Hui Chen, Nigel G. Halford, RugenXu, Ting He, Bangwei Yang, Longhua Zhou, HuiminGuo, ChenghongLiu

“…In a previous study, we developed a salt-tolerant barley doubled haploid (DH) line, designated as DH20, through mutagenesis combined with microspore culture, establishing it as an idea model for elucidating the mechanisms of salt tolerance. …”
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Surveillance of Mycoplasma agassizii in Texas tortoises (Gopherus berlandieri) for translocation with emphasis on treatment and recovery by Christin A. Moeller, Saren Perales, Wraith Rodriguez, Alynn M. Martin, Cord B. Eversole, Sandra Rideout-Hanzak, Paul Crump, Clayton D. Hilton, Scott E. Henke

“…We noted an additional 10 tortoises began displaying clinical signs of upper respiratory tract disease (URTD) after translocation, so we designed a trial to test tulathromycin (5 mg/kg body weight given intramuscularly once/week for 7 weeks) or oxytetracycline (8 mg/kg body weight given subcutaneously once/day for 14 days) as Mycoplasma treatments for symptomatic tortoises.ResultsWithin the donor and recipient sites, 56 (32.7%) and 8 (34.8%), respectively, had antibody titers suggestive of past exposure. …”
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HOTSED: A new integrated model for assessing potential hotspots of sediment sources and related sediment dynamics at watershed scale by Manuel La Licata, Alberto Bosino, Seyed Hamidreza Sadeghi, Mattia De Amicis, Andrea Mandarino, Andrea Terret, Michael Maerker

“…In this paper we introduce HOTSED, a novel, innovative GIS-based model designed for assessing potential hotspots of sediment dynamics at watershed scale. …”
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Practice and experience of pre-examination triage mode in the emergency department during COVID-19 epidemic (新型冠状病毒感染流行期间急诊科预检分诊模式的实践及体会)... by HOU Pengxiao (候朋晓), LI Ying (李影), LIU Fusheng (刘福生), REN Yaxing (任亚星), QIN Shasha (秦沙沙), HAN Jianping (韩建萍)

“…The hierarchic and zone management was designed to reduce medical risks, improve the overall efficacy of emergency triage, and ensure early identification and timely interventions for critically ill patients during COVID-19 epidemic. …”
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Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath by Alexander Braunsperger, Maximilian Bauer, Chaima Ben Brahim, Lea Seep, Dominik Tischer, Mirko Peitzsch, Jan Hasenauer, Sieglinde Hechenbichler Figueroa, Anna Worthmann, Joerg Heeren, Kenneth A. Dyar, Karsten Koehler, Ana Soriano-Arroquia, Martin Schönfelder, Henning Wackerhage

“…Abstract While the effect of time-of-day (morning versus evening) on hormones, lipids and lipolysis has been studied in relation to meals and exercise, there are no studies that have investigated the effects of time-of-day on ice bath induced hormone and lipidome responses. In this crossover-designed study, a group of six women and six men, 26 ± 5 years old, 176 ± 7 cm tall, weighing 75 ± 10 kg, and a BMI of 23 ± 2 kg/m2 had an ice bath (8–12 °C for 5 min) both in the morning and evening on separate days. …”
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miR-9-5p/HMMR regulates the tumorigenesis and progression of clear cell renal cell carcinoma through EMT and JAK1/STAT1 signaling pathway by Xinyang Niu, Dingheng Lu, Weitao Zhan, Jiazhu Sun, Yuxiao Li, Yuchen Shi, Kai Yu, Suyuelin Huang, Xueyou Ma, Xiaoyan Liu, Ben Liu

“…Subsequently, a series of in vivo and in vitro experiments were designed to elucidate the biological function of HMMR in ccRCC, including Transwell assays, CCK-8 assays, clone formation assays and subcutaneous xenograft experiments in nude mice. …”
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The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experien... by L. Lily Rosenthal, L. Lily Rosenthal, L. Lily Rosenthal, Carola Grinninger, Sarah Marie Ulrich, Robert Dalla Pozza, Nikolaus A. Haas, Paolo Brenner, Michael Schmoeckel, Sebastian Michel, Sebastian Michel, Sebastian Michel, Christian Hagl, Christian Hagl, Jürgen Hörer, Jürgen Hörer, Jürgen Hörer

“…The primary outcome was survival at the follow-up evaluation. The time point designated as “time 0” was defined as the time of heart transplantation. …”
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