Ivermectin vs moxidectin for treating Strongyloides stercoralis infection: a systematic review by Cesar Henriquez-Camacho, Jose A. Pérez-Molina, Dora Buonfrate, Paola Rodari, Eduardo Gotuzzo, Benilde Luengo, María Nieves Plana

“…There is evidence for moderate quality that moxidectin is non-inferior to, and as safe as ivermectin; however, more high-quality and well-designed trials are needed. For patients with some underlying immunosuppressive disorder, or in patients who are very young or very old, current data are insufficient to be recommended.…”
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Vonoprazan-Based Regimen Is More Useful than PPI-Based One as a First-Line Helicobacter pylori Eradication: A Randomized Controlled Trial by Masafumi Maruyama, Naoki Tanaka, Daisuke Kubota, Masayuki Miyajima, Takefumi Kimura, Koujiro Tokutake, Ryujiro Imai, Toru Fujisawa, Hiromitsu Mori, Yoshiaki Matsuda, Shuichi Wada, Akira Horiuchi, Kendo Kiyosawa

“…This randomized controlled trial was designed to assign 141 patients with H. pylori-positive gastritis to VPZ group (VPZ 20 mg, amoxicillin 750 mg, and clarithromycin 200 or 400 mg twice daily for 7 days) or PPI group (rabeprazole 20 mg or lansoprazole 30 mg, amoxicillin 750 mg, and clarithromycin 200 or 400 mg twice daily for 7 days). …”
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Exploring a high-level programming model for the NWP domain using ECMWF microphysics schemes by S. Ubbiali, C. Kühnlein, C. Schär, L. Schlemmer, T. C. Schulthess, T. C. Schulthess, M. Staneker, H. Wernli

“…We benchmark all prototype codes on three European supercomputers characterized by diverse graphics processing unit (GPU) and central processing unit (CPU) hardware, node designs, software stacks, and compiler suites. Once the application is ported to Python with GT4Py, we find excellent portability, competitive GPU performance, and robust execution in all tested scenarios including with single precision.…”
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Modified iris system: initial experience with a new technology for safety in hiatal surgery in pediatric patients by Joel Cazares, Eduardo De la Rosa-Bustamante, Jorge Colín-Garnica, Arturo Guillen-Cárdenas, Marbella Sepulveda-Valenzuela, Miguel Torres-Salas, Jorge Alberto Cantú-Reyes

“…The IRIS U-kit, originally designed for urology, was adapted to aid esophageal visualization. …”
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Identifying spatiotemporal patterns and drivers of fecal indicator bacteria in an urban lake for water quality assessment and management by Jimmy J. Dimpor, Otite P. Lucky, Dennis F. Kwarkye, Samuel Watts, Chukwuebuka P. Oguayo, Catherine O. Ojewole, Joseph Kusi

“…The designated uses of lakes connect individuals to the natural environment, but some can expose recreational users to pathogens associated with fecal contamination that cause waterborne illnesses. …”
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Voxel-Wise Brain-Wide Functional Connectivity Abnormalities in Patients with Primary Blepharospasm at Rest by Pan Pan, Shubao Wei, Huabing Li, Yangpan Ou, Feng Liu, Wenyan Jiang, Wenmei Li, Yiwu Lei, Yanqing Tang, Wenbin Guo, Shuguang Luo

“…The method of global-brain FC (GFC) was adopted to analyze the resting-state fMRI data. We designed the support vector machine (SVM) method to determine whether GFC abnormalities could be utilized to distinguish the patients from the controls. …”
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Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy by Khurram Shahzad, Martin Cadeiras, Sarfaraz Memon, Barry Zeeberg, Tod Klingler, Anshu Sinha, Esteban G. Tabak, Sreevalsa Unniachan, Mario C. Deng

“…Larger prospectively designed studies are needed to corroborate our hypothesis.…”
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KE-RSIC: Remote Sensing Image Captioning Based on Knowledge Embedding by Kangda Cheng, Erik Cambria, Jinlong Liu, Yushi Chen, Zhilu Wu

“…Current remote sensing image captioning methods often struggle to provide accurate and comprehensive descriptions due to their reliance on networks designed for natural images. Due to limited domain-specific knowledge in remote sensing, these networks often fail to accurately reflect the intrinsic semantic information of remote sensing categories. …”
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A multi-modal multi-branch framework for retinal vessel segmentation using ultra-widefield fundus photographs by Qihang Xie, Qihang Xie, Xuefei Li, Yuanyuan Li, Yuanyuan Li, Jiayi Lu, Jiayi Lu, Shaodong Ma, Yitian Zhao, Yitian Zhao, Jiong Zhang, Jiong Zhang

“…Additionally, we propose an enhanced UWF-based segmentation network in M3B-Net, specifically designed to improve the segmentation of fine retinal vessels. …”
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Unlocking the therapeutic mechanism of Caesalpinia sappan: a comprehensive review of its antioxidant and anti-cancer properties, ethnopharmacology, and phytochemistry by Estéfani Alves Asevedo, Estéfani Alves Asevedo, Livia Ramos Santiago, Livia Ramos Santiago, Hyo Jeong Kim, Rony Abdi Syahputra, Moon Nyeo Park, Rosy Iara Maciel Azambuja Ribeiro, Bonglee Kim

“…However, significant challenges remain, including the need to unravel the precise molecular mechanisms underlying its anticancer effects, refine extraction and isolation methods for bioactive compounds, and validate its safety and efficacy through well-designed clinical trials. Particularly noteworthy is C. sappan’s potential in combination therapies, where it may synergistically target multiple cancer pathways, enhance therapeutic outcomes, and mitigate adverse effects. …”
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Genetic and biochemical characterization of a radical SAM enzyme required for post-translational glutamine methylation of methyl-coenzyme M reductase by Roy J. Rodriguez Carrero, Cody T. Lloyd, Janhavi Borkar, Shounak Nath, Liviu M. Mirica, Satish Nair, Squire J. Booker, William Metcalf

“…In vitro data show that a B12-dependent radical SAM (rSAM) enzyme, designated MgmA, is responsible for this post-translational modification (PTM). …”
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A Method and Engineering Practice for a Fully Mechanized Caving Coalface to Rapidly Pass Through a Large Fault by Wei Zhang, Feili Yang, Jingyu Chang, Shengxun Zhao, Bin Xu, Jinyong Xiang

“…The main implementation steps of the method include designing the layout parameters of the pre-driven roadways, determining the width for rock pillars between the adjacent pre-driven roadways, construction of pre-driven roadways by smooth wall blasting, and controlling the surrounding rock deformation of the pre-driven roadways. …”
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Rapid and simple detection of Candida albicans using closed dumbbell-mediated isothermal amplification by Yanli Zhang, Xuhan Chen, Yeling Zhong, Fei Guo, Guifang Ouyang, Rui Mao

“…Optimal primers and accelerate primers (out primers and loop primers) were designed and selected after confirmation of the fundamental CDA primers to achieve more efficient CDA reaction for C. albicans detection (CA-OL-CDA).ResultsAfter establishment of the assay, 9 non-Candida albicans strains, including 3 Candida species were tested to negative by adopting the established CA-OL-CDA assay, indicated high specificity. …”
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Magnetic hybrid Pd/Fe-oxide nanoparticles meet the demands for ablative thermo-brachytherapy by Rogier van Oossanen, Alexandra Maier, Jérémy Godart, Jean-Philippe Pignol, Antonia G. Denkova, Gerard C. van Rhoon, Kristina Djanashvili

“…Objective To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power (SLP) and clinical constraints in the applied magnetic field.Methods Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness, were suspended in water and their SLPs were measured at varying magnetic fields (12–26 mT peak) and frequencies (50–730 kHz) with a commercial alternating magnetic field generator (magneTherm™ Digital, nanoTherics Ltd.).Results Validation of the heating device used in this study with commercial HyperMag-C nanoparticles showed a small deviation (±4%) over a period of 1 year, confirming the reliability of the method. …”
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Toward Sustainable Biocultural Ecotourism: An Integrated Spatial Analysis of Cultural and Biodiversity Richness in Colombia by Alejandra Echeverri, Natasha M. Batista, Stacie Wolny, Guido A. Herrera‐R, Federico Andrade‐Rivas, Allison Bailey, Anaid Cardenas‐Navarrete, Armando Dávila Arenas, Andres Felipe Díaz‐Salazar, Katherine Victoria Hernandez, Kelley E. Langhans, Bryam E. Mateus‐Aguilar, Dallas Levey, Andrew Neill, Oliver Nguyen, Andres Felipe Suárez‐Castro, Felipe Zapata, Natalia Ocampo‐Peñuela

“…Areas with great potential for biocultural ecotourism development largely coincide with designated Indigenous Reserves and Afro‐Colombian Territories. …”
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DRomics, a workflow to exploit dose-response omics data in ecotoxicology by Delignette-Muller, Marie Laure, Siberchicot, Aurélie, Larras, Floriane, Billoir, Elise

“…Coupled to dose-response experimental designs, they allow a non-targeted assessment of organism responses at the molecular level along an exposure gradient. …”
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Late-time Radio Brightening and Emergence of a Radio Jet in the Changing-look AGN 1ES 1927+654 by Eileen T. Meyer, Sibasish Laha, Onic I. Shuvo, Agniva Roychowdhury, David A. Green, Lauren Rhodes, Amelia M. Hankla, Alexander Philippov, Rostom Mbarek, Ari laor, Mitchell C. Begelman, Dev R. Sadaula, Ritesh Ghosh, Gabriele Bruni, Francesca Panessa, Matteo Guainazzi, Ehud Behar, Megan Masterson, Haocheng Zhang, Xiaolong Yang, Mark A. Gurwell, Garrett K. Keating, David Williams-Baldwin, Justin D. Bray, Emmanuel K. Bempong-Manful, Nicholas Wrigley, Stefano Bianchi, Federica Ricci, Fabio La Franca, Erin Kara, Markos Georganopoulos, Samantha Oates, Matt Nicholl, Main Pal, S. Bradley Cenko

“…The source was first designated a CL-AGN after an optical outburst in late 2017 and has since displayed considerable changes in X-ray emission, including the destruction and rebuilding of the X-ray corona in 2019–2020. …”
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A randomized double-blind clinical trial investigating the effects of ellagic acid on glycemic status, liver enzymes, and oxidative stress in patients with non-alcoholic fatty live... by Sara Mighani, Rasoul Samimi, Mohamadreza Rashidi Nooshabadi, Seyed Amir Farzam, Hossein Khadem Haghighian, Maryam Javadi

“…Considering the antioxidant features of Ellagic acid (EA), this study was designed to assess the effect of EA on some biochemical factors in patients with NAFLD. …”
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Local Binary and Multiclass SVMs Trained on a Quantum Annealer by Enrico Zardini, Amer Delilbasic, Enrico Blanzieri, Gabriele Cavallaro, Davide Pastorello

“…In practice, the fast local kernel support vector machine (FaLK-SVM) method, designed for efficient local SVMs, has been combined with quantum-trained SVM models for binary and multiclass classification. …”
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SumGPT: A Multimodal Framework for Radiology Report Summarization to Improve Clinical Performance by Tipu Sultan, Mohammad Abu Tareq Rony, Mohammad Shariful Islam, Samah Alshathri, Walid El-Shafai

“…The SumGPT technique was evaluated against several baseline models, including BERT + EfficientNet, XLM-RoBERTa + ViT, T5+ CLIP, VisualGPT (GPT-2+ ViT), and others, using a dataset explicitly designed for this task. The experimental results indicate that SumGPT outperformed all baseline models, achieving the highest performance across all metrics. …”
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