Action Imagery and Observation in Neurorehabilitation for Parkinson’s Disease (ACTION-PD): Development of a User-Informed Home Training Intervention to Improve Functional Hand Move... by Judith Bek, Paul S. Holmes, Chesney E. Craig, Zoë C. Franklin, Matthew Sullivan, Jordan Webb, Trevor J. Crawford, Stefan Vogt, Emma Gowen, Ellen Poliakoff

“…The home-based intervention, delivered using a tablet computer app, was iteratively designed by an interdisciplinary team, including people with PD, and further developed through focus groups and initial field testing. …”
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Ecological-based insights into bat populations in the Yucatán Peninsula under a One Health approach: coexistence or biophobia by Ma. Fernanda Sánchez-Soto, Osiris Gaona, Ricardo Mercado-Juárez, Ricardo Mercado-Juárez, Alfredo Yanez-Montalvo, Arit de León-Lorenzana, Gabriela Borja-Martínez, Gabriela Borja-Martínez, Daniela Zaldívar, Stephany Rodríguez-González, Erika N. Hernández-Villegas, Andres Moreira-Soto, Jan Felix Drexler, Gerardo Suzán, Ella Vázquez-Domínguez, Luisa I. Falcón

“…., microbiome) and, perhaps most importantly, conduct educational activities that foster an affinity for bats. We designed a multi-scale effort to characterize bat populations and their gut microbiome in urban (Mérida), agricultural (Tizimín), and conserved (Calakmul) landscapes of the YP, while conducting outreach activities to promote biophilic responses. …”
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UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases by Marco Capó, Silvia Vitali, Georgios Athanasiou, Nicole Cusimano, Daniel García, Garth Cruickshank, Bipin Patel

“…We rigorously evaluated these approaches both as robust age predictors for healthy individuals and as potential biomarkers for various neurodegenerative conditions, leveraging data from the UK Biobank, ADNI, and NACC datasets. To this end we designed a statistical framework to assess age prediction performance, the robustness of the prediction across cohort variability (database, machine type and ethnicity) and its potential as a biomarker for neurodegenerative conditions. …”
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Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

“…Methods To address this question, we established an in vitro model designed to study the interactions between pDCs and fibroblasts. …”
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Evaluating a large language model’s ability to answer clinicians’ requests for evidence summaries by Mallory N. Blasingame, Taneya Y. Koonce, Annette M. Williams, Dario A. Giuse, Jing Su, Poppy A. Krump, Nunzia Bettinsoli Giuse

“…Thus, we envision this being the first of a series of investigations designed to further our understanding of how current and future versions of generative AI can be used and integrated into medical librarians’ workflow. …”
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Study on the Freeze-Thaw Problems in the Winter Construction of the Lianghekou Earth-Core Rockfill Dam and the Countermeasures for Prevention by Qihao Yu, Xiu-Ling Ren, Pan Yue, Gui-Ke Zhang, Jun-Feng Wang, Yan-Hu Mu, En-Long Liu

“…And, the field tests demonstrate that the filling compaction degree of the frozen soils is difficult to meet the designed requirements. In order to effectively cope with the adverse effect of the freeze-thaw on the construction quality during the construction process, based on the analysis of the freeze-thaw characteristics of soils and its influence, and the energy exchange process of soils on-site, the principles and methods for establishing the freeze prevention system during the winter construction process are established, and a comprehensive monitoring system suitable for on-site is established in this paper. …”
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Race or Resource? BMI, Race, and Other Social Factors as Risk Factors for Interlimb Differences among Overweight Breast Cancer Survivors with Lymphedema by Lorraine T. Dean, Anagha Kumar, Taehoon Kim, Matthew Herling, Justin C. Brown, Zi Zhang, Margaret Evangelisti, Renata Hackley, Jiyoung Kim, Andrea Cheville, Andrea B. Troxel, J. Sanford Schwartz, Kathryn H. Schmitz

“…Tailoring physical activity and weight loss interventions designed to address BCRL severity by resource rather than race should be considered.…”
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PD-L1 Immunohistochemistry Comparability and Their Correlation with Clinical Characteristics in NSCLC by Chiao-En Wu, Ching-Fu Chang, Liao Kou-Sheng, Ju Chiang, Shih-Wei Lee, Yu-Chi Chiu

“…PD-L1 expression is an important predictive factor of response to therapy with immune checkpoint inhibitors (ICIs). This study was designed to retrospectively analyze the concordance of PD-L1 measurements using three different assays (Dako22C3, Dako28-8, and SP142) in NSCLC patients and to find possible predictors of high PD-L1 expression. …”
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The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target by Reem Alharthi, Monica Sueiro-Olivares, Isabelle Storer, Hajer Bin Shuraym, Jennifer Scott, Reem Al-Shidhani, Rachael Fortune-Grant, Elaine Bignell, Lydia Tabernero, Michael Bromley, Can Zhao, Jorge Amich

“…We further showed that the structure of the ligand-binding pocket of the fungal enzyme differs significantly from its human counterpart, suggesting that specific inhibitors can be designed. Therefore, in vivo transcriptomics is a powerful tool for identifying genes crucial for fungal pathogenicity that may encode promising antifungal target candidates.…”
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Dietary γ-Aminobutyric Acid Promotes Growth and Immune System Performance and Improves Erythropoiesis and Angiogenesis in Gibel Carp (<i>Carassius auratus gibelio</i>) by Xinlan Bai, Lu Zhang, Hualiang Liang, Dongyu Huang, Mingchun Ren, Haifeng Mi

“…An eight-week culturing experiment was designed with five experimental diets, with the actual GABA content being 368 mg/kg (G1, control group), 449 mg/kg (G2), 527 mg/kg (G3), 602 mg/kg (G4), and 675 mg/kg (G5). …”
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Enhancing Remote Sensing Semantic Segmentation Accuracy and Efficiency Through Transformer and Knowledge Distillation by Kang Zheng, Yu Chen, Jingrong Wang, Zhifei Liu, Shuai Bao, Jiao Zhan, Nan Shen

“…To address these issues, this study designs a hybrid approach that integrates knowledge distillation with a combination of CNN and transformer to enhance semantic segmentation in remote sensing images. …”
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FreshWater Watch: Investigating the Health of Freshwater Ecosystems, from the Bottom Up by Isabel Bishop, Amedeo Boldrini, Wim Clymans, Charlotte Hall, Heather Moorhouse, Stephen Parkinson, Kesella Scott-Somme, Ian Thornhill, Steven Loiselle

“…Herein, we outline the criteria used to develop a citizen science monitoring program for water quality, based on a standardized methodology designed to support the Agenda 2030 indicator 6.3.2 and the EU’s Water Framework Directive. …”
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The Influence of the Cu-Al₂O₃ Ratio of the Receiving Tube in a 50 MW Hybrid Solar Plant by Guillermo Benítez-Olivares, Alejandro Torres-Aldaco, Raúl Lugo-Leyte, José Javier Valencia-López, Luis Alberto Romero-Vázquez, Helen D. Lugo-Méndez

“…A 50 MWe hybrid solar thermal plant is proposed for Mulegé, Baja California Sur, Mexico, including a solar field designed to analyze the production of superheated steam during peak solar irradiance hours. …”
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The variability and predictability of summer southwest monsoon intensity measurement index across mainland indochina: from local synoptic to large scale perspectives by Kyaw Than Oo, Yinshuo Dong, Kazora Jonah

“…This study introduces a new Southwest Monsoon Intensity Index (SMII), based on sea level pressure (SLP), which offers a more comprehensive understanding of the monsoon’s intraseasonal to interannual variability and its associated climate anomalies. The SMII is designed to overtake the limitations of local indices, which often rely on data from only two costal stations and may lack the resolution necessary for seasonal outlooks or long-term forecast modeling. …”
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The availability of drugs for stable COPD treatment in China: a cross-sectional survey by Dongru Du, Xueru Hu, Qiunan Zuo, Dan Xu, Tao Zhu, Tao Fan, Jiao Yang, Weiguo Xu, Hailong Wei, Kangzhuo Baima, Ying Zhang, Yanhui Gu, Lei Chen, Fengming Luo, Yongchun Shen, Fuqiang Wen

“…A well-constructed questionnaire was designed according to the Chinese Guidelines for the Diagnosis and Management of COPD (revised version 2021). …”
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An “initial-engineering-end use” quasi-market pricing mechanism under cascading risk for cross-regional water rights trading by Xuxia Li, Huimin Wang, Gang Liu, Liu Yang, Zhou Fang, Yi Xiao, Xiaoying Lai, Li Gao, Ying Teng

“…The mechanism comprises three stages, each designed to address specific risks. To support these stages, data from field studies is used to calibrate three unique pricing models: the stochastic differential game, incomplete contract theory, and the Nash-bargaining model. …”
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VEGFR-2 Expression in Glioblastoma Multiforme Depends on Inflammatory Tumor Microenvironment by Jana Jaal, Marju Kase, Ave Minajeva, Mikk Saretok, Aidi Adamson, Jelizaveta Junninen, Tõnis Metsaots, Tõnu Jõgi, Madis Joonsalu, Markus Vardja, Toomas Asser

“…Target dependence on inflammatory tumor microenvironment has to be taken into consideration when treatment approaches that block VEGFR-2 signaling are designed.…”
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The philosophical foundations of digital twinning by David J Wagg, Christopher Burr, Jason Shepherd, Zack Xuereb Conti, Mark Enzer, Steven Niederer

“…We further argue that in order to enable emergent behaviors, digital twins should be designed to reconstruct the behavior of a physical twin by “dynamically assembling” multiple digital “components”. …”
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Enhanced Optical and Thermal Stability of Blue Pyrrole Derivatives for Color Filter in Image Sensors by Sunwoo Park, Sangwook Park, Saeyoung Oh, Hyukmin Kwon, Hayoon Lee, Kiho Lee, Chun Yoon, Jongwook Park

“…We designed and synthesized two novel blue pyrrole derivatives, 2-(3-cyano-4-(4-(dibutylamino)phenyl)-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)malononitrile (BAPCP) and 2-(3-cyano-4-(4-(dihexylamino)phenyl)-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)malononitrile (HAPCP), as potential candidates for use in image sensor color filters. …”
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Adaptive cognitive control in 4 to 7-year-old children and potential effects of school-based yoga-mindfulness interventions: an exploratory study in Italy by Lisa Toffoli, Giulia Stefanelli, Giulia Manca, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Michele Guidi, Francesca Incagli, Luca Sbernini, Luca Sbernini, Vincenza Tarantino, Giovanni Mento, Giovanni Mento

“…Furthermore, as part of an exploratory study designed to evaluate the feasibility of a school-based program in Italy, all children underwent a re-testing session after an 8-week intervention involving yoga-mindfulness.ResultsResults suggested that young children can exploit global probabilistic changes to optimize motor preparation/ inhibition while counterbalancing fatigue effects. …”
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