In Situ Gelling Dexamethasone Oromucosal Formulation: Physical Characteristics Influencing Drug Delivery by Daniel Krchňák, Ľudmila Balážová, Michal Hanko, Dominika Žigrayová, Miroslava Špaglová

“…The study focuses on the development of an in situ gelling dexamethasone (DEX) oromucosal formulation designed for the treatment of aphthous stomatitis. …”
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ANALYSIS OF THE INTERACTIONS OF NEURONAL APOPTOSIS GENES IN THE ASSOCIATIVE GENE NETWORK OF PARKINSON’S DISEASE by M. A. Yankina, O. V. Saik, P. S. Demenkov, E. K. Khusnutdinova, E. I. Rogaev, I. N. Lavrik, V. А. Ivanisenko

“…We previously developed the ANDSystem tool, designed to automatically extract knowledge from scientific publications and reconstruct on this basis associative gene networks describing the molecular genetic mechanisms of biological processes. …”
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Performance evaluation of R-1234yf as alternative to R-22 for date fruit drying machine by Mukhtar Ariyadi Hifni, Ariandi Andrameda Yurian, Jati Nugroho Putro Ardi, Sulistio Aji Dhanang, Aisyah Nyayu

“…Heat pump drying in the food industry is notable for its efficiency and energy savings. When designing a date fruit drying machine, it is crucial to consider heat transfer characteristics and performance, measured by parameters such as the coefficient of performance (COP), specific energy consumption (SEC), and specific moisture extraction rate (SMER). …”
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Li-doped C20 nanocage and its derivatives for gas sensing application: A density functional theory study by Poonam Parkar, Mohsen Doust Mohammadi, Ajay Chaudhari

“…Recovery time analysis highlighted that all nanocages displayed practical recovery times for H2S, with the C10B10 nanocage showing the shortest recovery time, emphasizing its potential as a highly efficient sensor for H2S detection. The designed nanocages show better gas sensing performance for H2S gas molecule than NH3.…”
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Multidisciplinary approach to functional somatic syndromes: study protocol for a population-based prospective cohort study by Hamidreza Roohafza, Harold Snieder, Fatemeh Hadizadeh, Peyman Adibi, Alireza Ani, Ahmad Vaez

“…The other aim is to develop a new delimitation of FSSs based on an integrated multidisciplinary approach comprising of phenotypic and multiomics data.Methods and analysis ISFUN is a population-based prospective cohort study designed to follow a population of randomly selected seemingly healthy adults (18–65 years) through annual visits during a 4-year observation period. …”
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MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing by Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan

“…Lab administrators can assign tasks to users with reminders for experiments or cage maintenance. Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. …”
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Cooperative game scheduling and revenue sharing strategy for virtual power plants considering scenery uncertainty by SONG Duoyang, XUE Tianliang, LI Yipu, TU Jintong, BI Yuhao, WANG Mankang

“…In order to realize the fairness of revenue distribution among alliances and members, a multifactor improvement shapley value method and a two-stage refinement of the revenue distribution scheme based on the parity cycle kernel method are designed. Finally, the example results show that the proposed method effectively improves the prediction accuracy of wind power, realizes the cooperative and complementary operation among alliances within the virtual power plant, and ensures the fairness and reasonableness of the revenue distribution among multiple subjects.…”
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A workplace organisational intervention to improve hospital nurses’ and physicians’ mental health: study protocol for the Magnet4Europe wait list cluster randomised controlled tria... by Peter Griffiths, Jonathan Drennan, Jackie Bridges, Luk Bruyneel, Jane Ball, Linda H Aiken, Douglas M Sloane, Anners Lerdal, Matthew McHugh, Herbert Smith, Anne Marie Rafferty, Reinhard Busse, Walter Sermeus, Julia Köppen, Lars E Eriksson, Kaat Siebens, Matthew D McHugh, Anne Scott, Ingeborg Strømseng Sjetne, Sydney Anstee, Peter Van Bogaert, Rikard Lindqvist, Linda Aiken, Douglas Sloane, Hans De Witte, Wilmar B Schaufeli, Hans De Witte, Simon Dello, Dorothea Kohnen, Claudia Bettina Maier, Lisa Smeds Alenius, Mary Del Guidice, Timothy Cheney, Claudia Maier, Joan Kleine, Elaine Lehane Vera McCarthy, Noeleen Brady, Monica Bukkøy Kjetland, Paul Van Aken, Danny Van Heusden

“…Magnet hospitals, a model shown to attract and retain staff in US research, creates positive work environments that aim to support the well-being of healthcare professionals.Methods and analysis Magnet4Europe is a cluster randomised controlled trial, with wait list controls, designed to evaluate the effects of organisational redesign, based on the Magnet model, on nurses’ and physicians’ well-being in general acute care hospitals, using a multicomponent implementation strategy. …”
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Potential antioxidant and cytoprotective effects of essential oil extracted from Cymbopogon citratus on OxLDL and H2O2 LDL induced Human Peripheral Blood Mononuclear Cells (PBMC) by Jamuna S., Sakeena Sadullah M.S., Ashokkumar R., Gokul Shanmuganathan, Senguttuvan Sivan Mozhi, Niranjali Devaraj S.

“…This study has been designed to explore the protective effect of C. citratus (lemon grass) against modified LDL (OxLDL and H2O2 LDL) induced cytotoxicity in Peripheral Blood Mononuclear Cells (PBMC). …”
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New formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations by Walaa Ali Abdelhalim, Ahmed R. Rabee, Saied M. Soliman, Mohamed Hagar, Esraa A. Moneer, Basant A. Bakr, Assem Barakat, Matti Haukka, Hanaa A. Rasheed

“…Abstract New formyl indole derivatives based on thiobarbituric acid were designed for targeting parasitological applications. …”
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Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-... by Rui Zhang, Xingyu Lin, Rongjie Lin, Zhenbin Chen, Chenfang Miao, Yao Wang, Xiaoqin Deng, Jianlong Lin, Shishui Lin, Shaohuang Weng, Min Chen

“…In this study, we successfully synthesized metformin-derived carbon dots (MCDs), and investigated the antirheumatic effect in vivo and in vitro. Designed MCDs could target inflamed cells and accumulate at the inflammatory joints of collagen-induced arthritis (CIA) rats. …”
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Study on Inhibitory Effect of Cavity on Gas Explosion Propagation by Zhuo Yan, Shujie Yuan, Zhongqing Li, Shicheng Gu, Chaomin Mu

“…Inspired by this, to explore a new method of gas explosion suppression, a rectangular steel cavity with a wall thickness of 10 mm, a length of 500 mm, a width of 800 mm, and a height of 200 mm was designed. The cavity was installed in a pipeline system to carry out experimental research and to investigate the law of attenuation of gas explosion flames and shock wave overpressure after passing through the cavity. …”
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Parameter Optimization for Dissimilar Aluminum Alloys Joined Using Friction Stir Additive Manufacturing: A Screening Study by Senthil Kumaran Selvaraj, Akash L. Manoj, Alan B. Mathew, Akash V. Govind, Govindaswamy Sundaramali, Utkarsh Chadha, Bhaskar Vajipeyajula, Albert E. Patterson

“…This work examines the effects of several process parameters (tool rotational speed, tool tilt angle, and tool transverse speed) on tensile strength and hardness using a 3‐factor L9 Taguchi designed experiment. Three cases were explored, one were AL 6061 was welded to AL 7075, one where AL 7075 was welded to AL 6061, and one where the data were mixed to get an “average” effect representative of large additively manufactured parts. …”
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Pretransplant Immune- and Apoptosis-Related Gene Expression Is Associated with Kidney Allograft Function by Dorota Kamińska, Katarzyna Kościelska-Kasprzak, Paweł Chudoba, Oktawia Mazanowska, Mirosław Banasik, Marcelina Żabinska, Maria Boratyńska, Agnieszka Lepiesza, Agnieszka Gomółkiewicz, Piotr Dzięgiel, Marian Klinger

“…In a prospective study, we analyzed pretransplant peripheral blood gene expression in87 renal transplant candidates with real-time PCR on custom-designed low density arrays (TaqMan). Results. Immediate posttransplant graft function (14-day GFR) was influenced negatively by TGFB1 (P=0.039) and positively by IL-2 gene expression (P=0.040). …”
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Mathematical model for droplet size prediction of gas-water nozzle based on orthogonal experiment by Xin WANG, Wenpu LI, He SHAO, Yiyi ZHENG, Yurong GAO, Xi CHEN

“…In order to understand the influence of process parameters and structural parameters of internal mixing gas-water nozzle on atomization characteristics, based on a self-designed experimental platform for atomization characteristics, the influence of air supply pressure, water supply pressure, gas-water convergence angle, mixing chamber length and outlet size on atomization characteristics was quantitatively analyzed by orthogonal experiment method, and then a prediction model of nozzle droplet Sauter mean diameter (SMD) was established by using multivariate nonlinear regression method. …”
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Exploring the optimal reconstruction strategy for Enneking III defects in pelvis bone tumors: a finite element analysis by Jiazhuang Zhu, Jianping Hu, Kunpeng Zhu, Xiaolong Ma, Zhen Huang, Chunlin Zhang

“…Based on the defect location and TO results, three reconstruction schemes were designed for each type of defect. We subsequently conducted simulations of static FEA under natural walking loads using ANSYS software (version 2022R1, Canonsburg, Pennsylvania, USA). …”
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Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses by Patrick Nelson, Noah Smith, Stanca Ciupe, Weiping Zou, Gilbert S. Omenn, Massimo Pietropaolo

“…Finally, we discuss the robustness of the model and its ability to assist experimentalists in designing studies to test complicated theories about the disease.…”
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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques by Joanna Zikos, Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko, Ala M. Shaqra, Celia A. Schiffer, Koen K. A. Van Rompay, Jonah B. Sacha, Diogo M. Magnani

“…These findings support the optimization of FcRn interactions in mAb therapies designed for administration during pregnancy.…”
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Meeting deepwater drilling challenges in Niger-Delta with high performance water-based mud by Chimezie Sidney Uduba, Ibrahim Ademola Fetuga, Olabode Thomas Olakoyejo, Monica Wobo, Antônio Marcos de Oliveira Siqueira, Joshua Kolawole Gbegudu, Franklin Onah Onazi

“…An experimental investigation was carried out on the high-performance water-based mud designed for drilling in the Niger delta region where clay type kaolinite is predominant. …”
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Beetroot (Beta vulgaris L.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model by Ali A. El Gamal, Mansour S. AlSaid, Mohammad Raish, Mohammed Al-Sohaibani, Shaza M. Al-Massarani, Ajaz Ahmad, Mohamed Hefnawy, Mohammed Al-Yahya, Omer A. Basoudan, Syed Rafatullah

“…The present investigation was designed to investigate the protective effect of (Beta vulgaris L.) beat root ethanolic extract (BVEE) on gentamicin-induced nephrotoxicity and to elucidate the potential mechanism. …”
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