Tecovirimat in the management of poxviruses: a narrative review of available evidence by Olalekan John Okesanya, Jerico Bautista Ogaya, Ikponmwosa Jude Ogieuhi, Mohamed Mustaf Ahmed, Bonaventure Michael Ukoaka, Ojoisimi Franca Jamgbadi, Deborah Oluwaseun Shomuyiwa, Don Lucero-Prisno Eliseo, Blessing Olawunmi Amisu, Olakulehin Adebusuyi, William K. Chung, Emery Manirambona, Nimat Bola Idris, Janet Alexis A. De los Santos

“…Results Ten studies assessing the effectiveness and safety of tecovirimat for poxvirus infections were evaluated, reporting diverse findings across different patient populations and study designs. Clinical trials have shown significant therapeutic potential. …”
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ThyroNet-X4 genesis: an advanced deep learning model for auxiliary diagnosis of thyroid nodules’ malignancy by Xiaoxue Wang, Yupeng Niu, Hongli Liu, Fa Tian, Qiang Zhang, Yimeng Wang, Yeju Wang, Yijia Li

“…To address this challenge, this study proposes a novel deep learning model, ThyroNet-X4 Genesis, designed to automatically classify thyroid nodules as benign or malignant. …”
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Impact of time-varying exposure on estimated effects in observational studies using routinely collected data: protocol for a cross-sectional study by Ling Li, Xin Sun, Jing Tan, Mei Liu, Wen Wang, Kevin Lu, Guowei Li, Jiayue Xu, Jeff Jianfei Guo

“…How well investigators designed, analysed and reported time-varying exposure, and to what extent the divergence that can be observed between different methods used for handling time-varying exposure in these studies remains uncertain. …”
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Accurately Tunable AuNC‐ZIF Content Architecture Based on Coordination‐Dissociation Mechanism Enables Highly Brightness Dual‐Site Fluorescent Biosensor by Junyang Chen, Yuqian Wang, Runpu Shen, Wei Li, Sainan Gao, Zhikang Xiao, Qiyan Lv, Xiaojie Song, Jianzhong Xu, Gaoxiang Xu, Huifang Cui, Zhaohui Li

“…The findings provide crucial insights into the relationship between the assembly and performance of AuNCs and ZIFs, offering guidance for designing ultrasensitive multifunctional biosensors applicable in the field of biosensing.…”
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Pyruvic Oxime Nitrification and Copper and Nickel Resistance by a Cupriavidus pauculus, an Active Heterotrophic Nitrifier-Denitrifier by Miguel Ramirez, Jennifer Obrzydowski, Mary Ayers, Sonia Virparia, Meijing Wang, Kurtis Stefan, Richard Linchangco, Domenic Castignetti

“…The microbe (a Cupriavidus pauculus designated as C. pauculus strain UM1) was examined for its ability to perform heterotrophic nitrification in the presence of Cu2+ and Ni2+ and to metabolize the xenobiotic phenol. …”
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The Development of a One-Step PCR Assay for Rapid Detection of an Attenuated Vaccine Strain of Duck Hepatitis Virus Type 3 in Korea by Cheng-Dong Yu, Jong-Yeol Park, Sang-Won Kim, Yu-Ri Choi, Se-Yeoun Cha, Hyung-Kwan Jang, Min Kang, Bai Wei

“…The method was specifically designed to target the critical single-nucleotide polymorphism (SNP) site (T→C at position 1143 in the VP0 gene) unique to the Korean vaccine strain AP04203-P100. …”
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Feature Representations Using the Reflected Rectified Linear Unit (RReLU) Activation by Chaity Banerjee, Tathagata Mukherjee, Eduardo Pasiliao Jr.

“…One important aspect of designing a neural network is the choice of the activation function to be used at the neurons of the different layers. …”
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Detection of Estrogen Receptor Status in Breast Cancer Cytology Samples by an Optical Nanosensor by Pooja V. Gaikwad, Nazifa Rahman, Pratyusha Ghosh, Dianna L. Ng, Ryan M. Williams

“…Although endocrine therapy for ER+ patients is widely available, there is a need for increased access to low‐cost, rapid, and accurate ER testing methods. In this work, we designed a near‐infrared optical nanosensor using single‐walled carbon nanotubes (SWCNT) as the transducer and an anti‐ERα antibody as the recognition element. …”
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Harnessing the potential of shared data in a secure, inclusive, and resilient manner via multi-key homomorphic encryption by David Ha Eun Kang, Duhyeong Kim, Yongsoo Song, Dongwon Lee, Hyesun Kwak, Brian W. Anthony

“…Grounded in statistical learning principles, we introduce the Multi-Key Homomorphic Encryption Logistic Regression (MK-HELR) algorithm, designed to execute logistic regression on encrypted multi-party data. …”
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Efficient Polarization Demosaicking Via Low-Cost Edge-Aware and Inter-Channel Correlation by Guangsen Liu, Peng Rao, Xin Chen, Yao Li, Haixin Jiang

“…The proposed algorithm is available in both lightweight and full versions, designed for different application requirements. Experiments on simulated and real DoFP images demonstrated that both versions achieve the highestt interpolation accuracy and speed, respectively, among existing interpolation-based algorithms and significantly enhanced visuals. …”
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Benchmarking human face similarity using identical twins by Shoaib Meraj Sami, John McCauley, Sobhan Soleymani, Nasser Nasrabadi, Jeremy Dawson

“…This network is trained on a tailored verification task designed to encourage the network to group together highly similar face pairs in the embedding space and achieves a test AUC of 0.9799. …”
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Effects of Repolishing Systems on Surface Characteristics of a 3D-Printed Permanent Material by Alessandro Vichi, Giovanni Mura, Federico Vannini, Sofia Baldani, Gaetano Paolone, Cecilia Goracci

“…Methods: Squared specimens of one 3DP permanent resin (Crown permanent, Formlabs) have been CAD-designed and 3D-printed. After the roughness, gloss, and color measurements, they were immersed in a coffee staining bath at 44 °C for 24 h and then measured again. …”
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Drought characteristics and propagation under anthropogenic impacts: A regional-scale modelling analysis in four Large Basins of China by Haoran Hao, Ningpeng Dong, Mingxiang Yang, Xin Huang, Hejia Wang, Hao Wang

“…Then, two controlled simulation experiments, namely the human altered scenario and the natural scenario, are designed to analyze the human impact on the drought characterisics and propagation. …”
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A Novel Linear Sparse Array with Reconfigurable Pixel Antenna Elements by Ming Li, Haiping Wei, Jiahao Zhao, Qingchang Tao, Zheng You

“…Specifically, an RPA with simultaneous polarization and pattern reconstruction capabilities, consisting of the driven patch and the parasitic pixels on the same layer of dielectric substrate, is firstly designed, which can work in several operation modes corresponding to steerable beam directions θ=0°;θxoz=25°, 45°;θyoz=15° with two circular polarizations in X-band. …”
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Effects of Exercise Training on Molecular Markers of Lipogenesis and Lipid Partitioning in Fructose-Induced Liver Fat Accumulation by Siham Yasari, Denis Prud'homme, Frédérique Tesson, Marek Jankowski, Jolanta Gutkowska, Emile Levy, Jean-Marc Lavoie

“…The present study was designed to investigate the impact of exercise training on lipogenic gene expression in liver and lipid partitioning following the ingestion of a high fructose load. …”
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Unveiling microbial communities with EasyAmplicon: A user‐centric guide to perform amplicon sequencing data analysis by Salsabeel Yousuf, Hao Luo, Meiyin Zeng, Lei Chen, Tengfei Ma, Xiaofang Li, Maosheng Zheng, Xin Zhou, Liang Chen, Jiao Xi, Hongye Lu, Huiluo Cao, Xiaoya Ma, Bian Bian, Pengfan Zhang, Jiqiu Wu, Renyou Gan, Baolei Jia, Linyang Sun, Zhicheng Ju, Yunyun Gao, Waqar Afzal Malik, Chuang Ma, Hujie Lyu, Yahui Li, Huiyu Hou, Yuanping Zhou, Defeng Bai, Yao Wang, Haifei Yang, Jiani Xun, Shengda Du, Tianyuan Zhang, Xiulin Wan, Kai Peng, Shanshan Xu, Tao Wen, Tong Chen, Yong‐Xin Liu

“…To further facilitate the researchers and enhance usability, we present a detailed protocol with a video recording that guides users through each step of the pipeline, including data preprocessing (quality filtering, chimera removal), amplicon sequence variant analysis, diversity analysis, and data visualization. The protocol is designed for ease of use, with each step documented, allowing researchers to execute the workflow without requiring complex scripting skills. …”
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Novel Scalable Topologies of High Power Density Quadratic Converters With Low Voltage Stress on Power Diode by Md Samiullah, Mohammed A. Al. Hitmi, Atif Iqbal, Shirazul Islam

“…This article introduces two novel designs of high power density nonisolated quadratic boost converters, which neither uphold the cascaded architecture nor involve coupled inductors in them. …”
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Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients by Ghaith Hamza Kamil, Mohammed Mezher Hussein, Raya Ezzat Maroof

“…Levels of Ca change and the FGF23 increase early in CKD. This study was designed to show the Correlation between FGF23 and Ca in chronic kidney disease patients. …”
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Cognitive load and neurodiversity in online education: a preliminary framework for educational research and policy by Anne-Laure Le Cunff, Brandon-Lee Martis, Caitlin Glover, Emily Ahmed, Rhian Ford, Vincent Giampietro, Eleanor J. Dommett

“…This theoretical paper presents the development and analysis of an inclusive educational framework designed to manage cognitive load for neurodivergent students in online learning environments. …”
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Navigating the energy crisis: automakers’ coopetition strategies under dual credit policy by Yuan Kaifu, Wang Chuanji, Xiao Fang

“…To tackle the energy and climate crises and achieve sustainable development, China has designated the development of new energy vehicles (NEVs) as a national strategy. …”
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