Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports by Lee Shepstone, John F Potter, Lee Hooper, Asmaa Abdelhamid, Amy Jennings, Paul R Hunter, W Garry John, Neil P Walsh, Adam Ali, Diane K Bunn, Susan Kerry, Gregor Lindner, Carmen A Pfortmueller, Fredrik Sjöstrand, Susan J Fairweather-Tait

“…Objectives To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people.Design Diagnostic accuracy study.Participants Older people (≥65 years) in 5 cohorts: Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community), Dehydration Recognition In our Elders (DRIE, living in residential care), Fortes (admitted to acute medical care), Sjöstrand (emergency room) or Pfortmueller cohorts (hospitalised with liver cirrhosis).Reference standard for hydration status Directly measured serum/plasma osmolality: current dehydration (serum osmolality >300 mOsm/kg), impending/current dehydration (≥295 mOsm/kg).Index tests 39 osmolarity equations calculated using serum indices from the same blood draw as directly measured osmolality.Results Across 5 cohorts 595 older people were included, of whom 19% were dehydrated (directly measured osmolality >300 mOsm/kg). …”
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Hubungan Faktor Risiko terhadap Kejadian Asma pada Anak di RSUP Dr. M. Djamil Padang by Adefri Wahyudi, Finny Fitry Yani, Erkadius .

“…Djamil Padang. Research design was case-control study. The pediatric patients in RSUP Dr. …”
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Wearable Textile Patch DSSRS Antenna for Body Tumors Detection with Reduced SAR by M.M. Hasan Mahfuz, Md Rafiqul Islam, Norun Farihah Abdul Malek, Mohamed Hadi Habaebi, Nazmus Sakib, Elham Baladi

“…The planned antenna has dual symmetrical slots as well as a ring-shaped slot (DSSRS) at the top, and it is in the form of a radiating rectangular patch with a ground plane. The design procedure has been finished with the help of CST MWS, and the next step will be to fine-tune the parameters of the antenna structure to achieve resonance at the ISM band (5.79 GHz). …”
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Assessing learning, behaviour, and stress level in goats while testing a virtual fencing training protocol by L. Wilms, D. Hamidi, C.H.U. Lüntzel, M. Hamidi, M. Komainda, R. Palme, J. Isselstein, S. Waiblinger, M. Egerbacher

“…Twenty adult ‘Blobe’ goats with offspring were divided into two groups and assigned to the VF or physical fencing treatment in a cross-over design with two periods of 12 days each. The VF treatment involved a virtual fence at one side of the paddock, to which the goats were gradually introduced over the first 2 days (additional physical fence or posts as visual support). …”
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The multidisciplinary approach to the treatment of paediatric chronic pain: a qualitative analysis through focus groups by Aldana Paola Ercolano, Sabrina Galvan, Tessa Louise Marchesan, Alessia Gavioli, Gerardo Papa, Mariarita Todaro, Lidia Berforini D’Aquino, Alessia Zanatta, Andrea Vianello

“…Methods: The study adopted a qualitative design, utilizing the Focus Group technique and unstructured interviews, following Consolidated Criteria for Reporting Qualitative Research (COREQ) guidelines. …”
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Self-reported determinants for subjective financial distress: a qualitative interview study with German cancer patients by Eva Winkler, Katja Mehlis, Bastian Surmann, Wolfgang Greiner, Andrea Züger, Viktoria Mathies, Sophie Pauge, Luise Richter, Thomas Ernst, Natalja Menold

“…To better understand subjective financial distress, the presented study explores self-reported determinants for subjective financial distress in German patients with cancer, aiming to inform a new German-language patient-reported outcome measure for determining the financial effects of a tumour disease.Design Semistructured interviews with n=18 patients with cancer were conducted between May 2021 and December 2021. …”
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Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers by Liming Liang, Xinyu Wang, Yue Zhu, Xu Xia, Runfeng Shi, Huilin Cao, Meixin He, Yuyu Wang, Caizhen You

“…In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014–2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.Design Bibliometric analysis through data analysis and visual mapping.Data sources Scientific articles.Data extraction and synthesis ‘Vaccine’ and ‘vaccines’ were used in the WoS database to retrieve the publications and to adequately collect the data; Microsoft Excel was used for data analysis; and VOSviewer was used for visual description of data. …”
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Trends in certifications of overall vision impairment and that due to diabetic retinopathy/maculopathy in England and Wales, 2009/2010 to 2019/2020: a retrospective database analys... by Catey Bunce, Gwyn Samuel Williams, David Owens, Wen Xing, Rhianon Reynolds, Antra Zekite, Declan Flanagan, RL Thomas, Rebecca John

“…The focus is on diabetic retinopathy/maculopathy as the key causative factor.Design Retrospective database analysis.Setting England and Wales.Participants Individuals certified as SI or SSI.Outcome measures Trends in certification of vision impairment in England and Wales due to any cause, with specific attention to diabetic retinopathy.Methods Certifications of vision impairment made by ophthalmologists in England and Wales were recorded and copies were sent to Moorfields Eye Hospital for epidemiological analysis. …”
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Comparative analysis of ChatGPT and Gemini (Bard) in medical inquiry: a scoping review by Fattah H. Fattah, Fattah H. Fattah, Abdulwahid M. Salih, Abdulwahid M. Salih, Ameer M. Salih, Ameer M. Salih, Saywan K. Asaad, Saywan K. Asaad, Abdullah K. Ghafour, Rawa Bapir, Rawa Bapir, Rawa Bapir, Berun A. Abdalla, Berun A. Abdalla, Snur Othman, Sasan M. Ahmed, Sasan M. Ahmed, Sabah Jalal Hasan, Yousif M. Mahmood, Fahmi H. Kakamad, Fahmi H. Kakamad, Fahmi H. Kakamad

“…Data collected from the studies included the first author's name, the country where the study was conducted, the type of study design, publication year, sample size, medical speciality, and the accuracy and response length.ResultsThe initial search identified 64 papers, with 11 meeting the inclusion criteria, involving 1,177 samples. …”
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Feasibility and acceptability of an integrated mind-body intervention for depression: whole-body hyperthermia (WBH) and cognitive behavioral therapy (CBT) by Ashley E. Mason, Anoushka Chowdhary, Wendy Hartogensis, Chelsea J. Siwik, Osnat Lupesko-Persky, Leena S. Pandya, Stefanie Roberts, Claudine Anglo, Patricia J. Moran, J. Craig Nelson, Christopher A. Lowry, Rhonda P. Patrick, Charles L. Raison, Frederick M. Hecht

“…Improved mood from pre-post the initial WBH session predicted pre-post treatment BDI-II change (36.2%; rho = 0.60, p = 0.038); mood changes pre-post the first CBT session did not.Limitations Small sample size and single-arm design limit generalizability.Conclusion An integrated mind-body intervention comprising weekly CBT sessions and bi-weekly WBH sessions was feasible. …”
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How Uremic Toxins Alter Atorvastatin Disposition: Molecular Mechanisms of Inhibition of the Enzyme CYP3A4 by Ashna Asim, Fen Wang, Dong Pu, Sisi Wang, Dian Wang, Wenwen Li, Feng Yu, Li Ji

“…Aims: To assess ways in which PBUTs alter the CYP450 enzymes in hepatocytes as well as the possible effects of specific PBUTs on the metabolism and excretion of atorvastatin (ATV). Study Design: An experimental study. Methods: The experimental group was treated with long-term MHD for > 3 months, estimated-glomerular filtration rate (e-GFR) < 15 ml/min, normal Alb level (35.0-55.0 g/l), and no urine; the control group was not treated with hemodialysis, e-GFR < 60 ml/min, normal Alb level, and normal urinary excretion function. …”
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Larval rearing of kelabau fish Osteochilus melanopleurus, Bleeker 1852 with different live feed by Nur Asiah, Netti Aryani, Benny Heltonika

“…The research was conducted in a Complete Randomized Design (CRD), 3 treatments and 3 replicates. The tested animals used were 7-Dpc (Day post hatch) 90 kelabau fish (Ostechilus melanopleurus) larvae with an initial average length of 0.50 ± 0.06 cm and an initial weight of 0.03 ± 0.02 g. …”
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Oxygenation targets for endovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocol for a single-centre, open-label randomised controlled trial by Anxin Wang, Zhengfang Hu, Ruquan Han, Fa Liang, Youxuan Wu, Minyu Jian, Xinyan Wang, Yunzhen Wang, Haiyang Liu, Xuan Hou, Kangda Zhang, Zihui Zhang

“…The standardised research protocol adopted in this trial is designed to enhance anaesthesiologists’ understanding of respiratory management for AIS patients during EVT. …”
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Pengembangan Internet Of Things (IOT) Dalam Perekaman Data Iklim Mikro Dengan Platform Thingsboard by Heru Nurwarsito, Resnu Wahyu Adaby

“…The method used in this study is experimental with the design in this study consisting of designing sensor nodes and designing a recording system with the Thingsboard platform. …”
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Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma by P. Horwich, C. MacKay, M. Bullock, S. M. Taylor, R. Hart, J. Trites, L. Geldenhuys, B. Williams, M. H. Rigby

“…Abstract Objective Evaluate the oncologic outcomes and cost analysis of transitioning to a specimen oriented intraoperative margin assessment protocol from a tumour bed sampling protocol in oral cavity (OCSCC) and oropharyngeal squamous cell carcinoma (OPSCC). Study design Retrospective case series and subsequent prospective cohort study Setting Tertiary care academic teaching hospital Subjects and methods Retrospective case series of all institutional T1-T2 OCSCC or OPSCC treated with primary surgery between January 1st 2009 – December 31st 2014. …”
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Carboxylated Graphene: An Innovative Approach to Enhanced IgA-SARS-CoV-2 Electrochemical Biosensing by Luciana de Souza Freire, Ariamna María Dip Gandarilla, Yonny Romaguera Barcelay, Camila Macena Ruzo, Barbara Batista Salgado, Ana P. M. Tavares, Francisco Xavier Nobre, Julio Nino de Souza Neto, Spartaco Astolfi-Filho, Ștefan Țălu, Pritesh Lalwani, Niranjan Patra, Walter Ricardo Brito

“…This device shows considerable potential because of its fast response time, miniaturized design facilitated by SPCEs, reduced sample volume requirements, high sensitivity and specificity, low detection limits, and signal enhancement achieved through nanomaterial integration.…”
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Holistic health and social care outreach for people experiencing homelessness with recent non-fatal overdose in Glasgow, Scotland: the Pharmacist and third sector Homeless charity... by Vibhu Paudyal, Nicola Greenlaw, Frances S Mair, Kate Stock, Andrew McPherson, Andrea E Williamson, Richard Lowrie, Donogh Maguire, Steven Ross, James Roy Robertson, Alison Boyle, Clare Duncan, Rebecca Blair, Cian Lombard, Fiona Hughes, Jane Moir, Ailsa Scott, Frank Reilly, Laura Sills, Jennifer Hislop, Stephen Wishart, David Brannan, Rebekah Ramage

“…Objectives To examine randomised controlled trial (RCT) progression criteria including emergency department (ED) attendance and non-fatal overdose, from a holistic, integrated health and social care outreach intervention (PHOENIx), for people experiencing homelessness with recent non-fatal street drug overdose.Design Pilot RCT. 1:1 randomisation to PHOENIx plus usual care (UC) or UC.Setting Glasgow, Scotland.Participants 128 adults experiencing homelessness with at least one non-fatal street drug overdose in the preceding 6 months.Interventions Pharmacists from the National Health Service and third sector homelessness workers offered weekly outreach. …”
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Factors associated with failure of humerus nonunion surgery in patients with initial nonoperative management by Alexander Hysong, MD, Noah Harrison, MD, Samuel Posey, MD, Ziqing Yu, MS, Andrew T. Chen, MD, Patrick Pallitto, MD, Joseph R. Hsu, MD, William Obremskey, MD, Evidence-Based Musculoskeletal Injury and Trauma Collaborative (EMIT), Hassan Mir, MD, Roman M. Natoli, MD, PhD, Ishani Sharma, MD, MBA, Jenna Jones, Med, Luke A. Lopas, MD, Hassan Farooq, MD, Robert D. Zura, MD, Alexander Padovano, MD, Nathaniel Koutlas, MD, Steve Hemmerly, BS, Elsa Rodriguez, MD, Daniel E. Pereira, MD, Sharon Babcock, MD, Gabriel James Sowards, BS, Martha Holden, AAS, AA, Anna N. Miller, MD, Marc Schatz, MD, Jessica Rivera, MD, PhD, Katrina Bang, MD, Kamryn King, BS, Zachery Hong, BA, Jarrod Dumpe, MD, Gabriella Lea Stribling, BS, Merritt John Thompson, MD, Tracy Johns, MSN, RN-BC, Rachel Seymour, PhD, Susan Odum, PhD, Stephen Sims, MD, Olivia Rice, MD, Ainsley Bloomer, MD, Katheryn Peterson, BSPH, Amber Stanley, BSPH, Mario Cuadra, MD, Gisele Bailey, MS, Matthew Braswell, MD, Landon Bulloch, MD, William Haynes, MD, Josef Jolissaint, MD, Julia Mastracci, MD, Andrew Wohler, MD, Eddie Komie Afetse, BS, BA, Cara Girardi, Juliette Sweeney, BS, Benjamin Averkamp, MD, Meghan Wally, PhD, Madhav Karunakar, MD, Kevin Phelps, MD, Laurence Kempton, MD, Christine Churchill, MA, CCRP, David Macknet, MD, Hannah Pollock, BS, Rodney Arthur, MS, Samuel Cohen-Tanugi, Isaac Boateng, James Michael Ruth, BS, Joseph Michalski, MD, Anna Hemminger, BS, Kathryn Leighty, Mir Ibrahim Sajid, MD, Thea Lance, BA, William Hunter Waddell, MD, Andres Fidel Moreno Diaz, MD, Joseph Gutbrod, BS, Christopher G. Herbosa, BS

“…To describe operative results after humerus nonunion surgery in patients whose initial humerus shaft fracture (OTA/AO code 12) was treated nonoperatively and to identify risk factors of nonunion surgery failure in the same population. Design:. Case series. Setting:. Nine academic level 1 trauma centers. …”
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Evaluasi Faktor Manfaat Sistem Lingkungan Pembelajaran 3 Dimensi Berbasis Multi-User Virtual Reality (MuVR) by Adhi Rizal, Dadang Yusup, Apriade Voutama

“…However, there were several design aspect problems identified related to the lack of instructions of information in the system regarding procedures on how to enter or quit system and the absence of information on how to participate in learning activities. …”
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Investigation of the optimal platinum-based regimen in the postoperative adjuvant chemotherapy setting for early-stage resected non-small lung cancer: a Bayesian network meta-analy... by Li Zhang, Wen-Feng Fang, Yi Lv, Lan-Lan Pang, Jia-Di Gan, Yi-Hua Huang, Jun Liao, Wael Abdullah-Sultan Ali

“…Objective This study aimed to compare the efficacy and safety of different platinum adjuvant chemotherapy regimens for early-stage resected non-small-cell lung cancer (NSCLC).Design Systematic review with network meta-analysis of randomised trials.Data sources PubMed, EMBASE, The Cochrane Library, Web of Science and Scopus Google Scholar were searched through 12 March 2021.Eligibility criteria Eligible randomised controlled trials (RCTs) comparing the postoperative platinum chemotherapy regimen with the observation-controlled group or comparing two platinum chemotherapy regimens head-to-head were included.Data extraction and synthesis The primary outcome was the efficacy of adjuvant chemotherapy regimens including relapse-free survival (RFS), overall survival (OS), 2-year, 3-year, 5-year RFS rate and OS rate. …”
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