AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…To address these issues, we introduce AiGPro, a novel multitask model designed to predict small molecule agonists (EC50) and antagonists (IC50) across the 231 human GPCRs, making it a first-in-class solution for large-scale GPCR profiling. …”
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Pragmatic performance, its relationship with symptom severity, and early clinical predictors of pragmatics in 5 ~ 6-year-old children with autism spectrum disorder by Lu Qian, Ning Ding, Hui Fang, Ting Xiao, Bei Sun, HuiYun Gao, XiaoYan Ke

“…Furthermore, this study provides new insights into potential targets for pragmatic interventions, and interventions can be designed to promote SJE between caregivers and children in future work.…”
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A first study on sperm sexing in water buffalo through magnetic nanoparticles by Syed Murtaza Hassan Andrabi, Muhammad Hammad Fayyaz, Muhammad Shafiq Haider, Ghulam Muhammad Ali

“…Therefore, this study was designed to optimize the magnetic nanoparticles (MNPs) based sperm sexing technique in water buffalo. …”
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Implementasi Metode Longest Common Subsequences untuk Perbaikan Kata pada Kasus Analisis Sentimen Opini Pembelajaran Daring di Media Sosial Twitter by Alfisyar Jefry Pranata, Yuita Arum Sari, Edy Santoso

“…Therefore, the World Health Organization (WHO) has designated Coronavirus as a pandemic. This results in all activities that were previously face-to-face or offline (offline) becoming online (online), including teaching and learning activities. …”
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A Novel Artificial Intelligence–Enhanced Digital Network for Prehospital Emergency Support: Community Intervention Study by Ji Hoon Kim, Min Joung Kim, Hyeon Chang Kim, Ha Yan Kim, Ji Min Sung, Hyuk-Jae Chang

“…This community-based, nonrandomized controlled intervention study was designed to evaluate the effectiveness of the CONNECT-AI system in 2 regions of South Korea, each of which operated an intervention and a control period, each lasting 16 weeks. …”
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Prevalence of Preoperative Anxiety and Associated Factors Among Surgical Patients: Systematic Review and Meta-Analysis in Ethiopia by Magarsa Lami, Abraham Negash, Jerman Dereje, Ahmed Hiko, Sinetibeb Mesfin, Arsema Gebreyesus, Nano Belama, Nesredin Ahmed Omer, Bikila Balis, Usmael Jibro

“…Methods: In this study, all observational study designs conducted in Ethiopia were included while studies that did not report our main outcome of interest or did not meet the quality criteria by Joanna Briggs Institute (JBI) critical appraisal techniques were excluded. …”
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Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“…Conclusions we provide the proof-of-concept for the use of modified GAA-tailored U1 snRNAs, designed to potentiate the recognition of the GAA exon 2 5’ss, as therapeutic tools to correct the aberrant transcripts carrying variants that affect exon 2 splicing, including the common c.-32-13T>G variant.…”
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A dual-band microwave sensor for glucose measurements utilizing an enclosed split ring metamaterial-based array by Abhishek Kandwal, Ziheng Ju, Louis W.Y. Liu, Rohit Jasrotia, Choon Kit Chan, Zedong Nie, Ali M. Almuhlafi, Hamsakutty Vettikalladi

“…The backside of the PET substrate was fabricated with a defected ground plane designed to suppress the Q-factor associated with 4.5 GHz while leaving the Q-factor associated with 9.2 GHz unchanged. …”
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The effect of active and passive smoking during pregnancy on birth outcomes: A cohort study in Shanghai by Xiaokai Wang, Xia Gao, De Chen, Xuelian Chen, Qingwei Li, Jiani Ding, Fangyuan Yu, Xiaoyun Zhu, Nannan Zhang, Yifang Chen

“…According to the smoking status of pregnant women, they were divided into three groups: active smokers, passive smokers and non-smokers. A self-designed questionnaire was utilized to conduct the survey, and their pregnancy outcomes were tracked and followed up. …”
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Soil chemical factors contributing to differences in bacterial communities among tea field soils and their relationships with tea quality by Shuning Zhang, Shuning Zhang, Naoki Yanagisawa, Mio Asahina, Hiroto Yamashita, Hiroto Yamashita, Hiroto Yamashita, Takashi Ikka, Takashi Ikka, Takashi Ikka, Takashi Ikka

“…While the relationships between soil bacterial communities and plant nutrient status have been investigated, the specific role by which soil bacterial communities interacted with soil properties to influence tea plant nutrients and quality remained underexplored.MethodsIn this study, different soil types were collected from tea gardens and designated as soil A (pH 3.41), soil B (pH 3.75), soil C (pH 4.16), soil D (pH 4.17) and soil E (pH 5.56) based on the initial soil pH. …”
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Problems And Challenges Of Attendance In Medical Students by Muhammad Khurram

“…Medical training in Large Group Interactive Sessions and Clinical Clerkships is designed to equip students with knowledge, skills, and experience necessary to practice medicine safely and effectively. …”
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Adopting Positive Selection Technology and Improving Seed Quality in Smallholder Potato Farmers in South-Western Uganda. by Kajura, Tibanyendera Deo

“…Demographic, socio-economic, institutional and technological factors that affect the adoption of technologies should be thought of by government and development agencies involved in designing intervention strategies focused on seed quality improvement. …”
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Application of Fuzzy Hierarchy Analysis method to identify factors on the professional development of newly graduated teachers from Farhangian University by Nader Habibzadeh, Ebrahim Salehiomran, Saeed Ghiyasinoshan

“…Theoretical Framework Professional development Professional development is formal and informal support and activities designed to help teachers, and includes school-based training and education and activities such as coaching, consulting, self-study, and research (Coldwell, 2017). …”
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Business targeting in Iran: a hybrid simulation-optimization approach by amir mansour tehranchian, Sogand Hoseinnia Chafjiri

“…In the country of Iran, a 10-year strategy for the period of 2021-2031 has been designed and implemented so that people with different degrees of desirability are employed. …”
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Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…Our primary innovation lies in developing an arbitrary user-pairing strategy for NOMA-based systems to secure short-packet delivery for IoT applications by jointly designing the power allocation policy and RIS’s phase shifter. …”
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Efficient Hydrolysis of Sugar Beet Pulp Using Novel Enzyme Complexes by Maria I. Komarova, Margarita V. Semenova, Pavel V. Volkov, Igor A. Shashkov, Alexandra M. Rozhkova, Ivan N. Zorov, Sergei A. Kurzeev, Aidar D. Satrutdinov, Ekaterina A. Rubtsova, Arkady P. Sinitsyn

“…The current study was designed with a primary objective that focused on the development of a strain that had the potential for enhanced productivity and the capacity to produce enzymes suitable for beet pulp hydrolysis. …”
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Shared prognostic information in amyotrophic lateral sclerosis – systematic assessment of the patients’ perception of neurofilament light chain and the ALS functional rating scale... by Lukas Maximilian Möhwald, André Maier, Torsten Grehl, Ute Weyen, Patrick Weydt, René Günther, Paul Lingor, Bettina Göricke, Susanne Petri, Julian Grosskreutz, Matthias Boentert, Isabell Cordts, Jochen H. Weishaupt, Johannes Dorst, Christoph Münch, Thomas Meyer, Petra Baum

“…Methods In a multicenter study, 149 ALS patients were assessed for their perception of shared information about NfL and ALSFRS-R using an investigator-designed survey and established questionnaires. The recommendation of NfL and ALSFRS-R to fellow patients was assessed using the Net Promoter Score (NPS). …”
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In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey IκBα-siRNA by Zhaoxing Ou, Rui Zeng, Yifan Lin, Si Zhang, Mohammad Alzogool, Peng Zeng, Yuqing Lan

“…Three IκBα-specific double-stranded siRNAs were designed and synthesized. They were transfected into primarily cultured cynomolgus monkey CM cells and TM cells. …”
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Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies by B. Dumont, C. Barlagne, P. Cassart, J.E. Duval, A. Fanchone, J-L. Gourdine, O. Huguenin-Elie, Y. Kazakova, J. Klötzli, A. Lüscher, E. Oteros-Rozas, D. Pomies, M.G. Rivera Ferre, W.A.H. Rossing, V. Stefanova, A. Swartebroeckx, C. Zagaria

“…Long-term commitment from local practitioners is required so that co-designed solutions are implemented, which can strengthen the economic and social viability of animal production areas.…”
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FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

“…The present study was designed to determine whether FAM134B is expressed in SGNs of C57BL/6 mice and, if so, to explore the potential function of FAM134B in Cis-induced SGN damage in vitro.MethodsMiddle turns of neonatal murine cochleae were cultured and treated with 30 μM Cis in vitro. …”
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