Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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Reconsidering routine admission for children under age 3 undergoing partial tonsillectomy: a prospective study by Ameen Biadsee, Craig Nathanson, Or Dagan, Firas Kassem, Avishai Stahl, Tova Mishali, Yaniv Ebner, Brian Rotenberg

“…A special protocol was designed, including follow-up at 2-, 4-, 6-, 8- and 24-h after surgery. …”
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Exploring the relationship between Total Athleticism score and CrossFit® Open Performance in amateur athletes: single measure involving body fat percentage, aerobic capacity, muscl... by Ramires Alsamir Tibana, Fábio Hech Dominski, Alexandro Andrade, Nuno Manuel Frade de Sousa, Fabricio Azevedo Voltarelli, Ivo Vieira de Sousa Neto

“…Furthermore, coaches can potentially apply this useful tool for monitoring athletic performance and designing training sessions that address specific areas of CrossFit® performance. …”
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Is surgery superior for distal ulna fractures? a comprehensive systematic review and meta-analysis by Zakaria Chabihi, Brahim Demnati, Mohamed Moussadiq, Tariq Aalil, Yassine Fath El Khir, El Mehdi Boumediane, Mohamed Amine Benhima, Imad Abkari

“…Future research should focus on standardizing study designs to improve the quality of evidence in the management of distal ulna fractures. …”
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Community-Based Assessment of Knowledge, Attitudes, and Practices Towards COVID-19: an Epidemiological Survey in Kurdistan Region, Iraq by Zhino Rawf Ali, Bayan Omar Sharif, Aram Salih Mohammed Amin Kamali, Varin Tofiq Abbas, Azad Karim Ahmed, Shaho Osman Mahmood, Chiman Jamal ahmed, Sarwat Ahmed Abdulqader

“…A self- constructed questionnaire was used for data collection and it was designed according guidelines, literatures, and articles concerning COVID-19; which consisted of 40 variables. …”
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THE INSTITUTIONALIZATION OF GLOBAL STRATEGIES FOR THE TRANSFORMATION OF SOCIETY AND EDUCATION IN THE CONTEXT OF CRITICAL THEORY by Viktor V. Zinchenko

“…It consider a model of «critical social philosophy of education», as embodied in the programs of social development and learning, which are primarily designed to teach people how to lead an independent and original research themselves, society and knowledge systems. …”
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Innovative MOF-enhanced electroanalytical approach for sensitive sunitinib malate detection in renal carcinoma patients using CuO/lanthanum MOF-modified carbon paste electrode by Azza H. Rageh, Mohamed I. Said, Asmaa Abdeltawab, Fatma A.M. Abdel-aal

“…The main aim of this work is to develop a highly sensitive, selective, and cost-effective electrochemical sensor for detecting sunitinib malate (SUN) in serum samples collected from renal cancer patients. The designed sensor was based on using CuO nanoparticles/lanthanum 1,4-napthalene dicarboxylic acid (NDC) MOF-modified carbon paste electrode (CuO NPs/LaNDC-MOF/CPE) coupled with square-wave adsorptive anodic stripping voltammetry (SW-AdASV) as the electrochemical technique. …”
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MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer by Shamima Afrin Ruma, Rufus Vinod, Shruti Jain, Kaisa Huhtinen, Johanna Hynninen, Janne Leivo, Kim Pettersson, Karin Sundfeldt, Kamlesh Gidwani

“…Abstract Glycosylation changes of circulating proteins carrying the CA19-9 antigen may offer new targets for detection methods to be explored for the diagnosis of epithelial ovarian cancer (EOC). Search for assay designs for targets initially captured by a CA19-9 antigen reactive antibody from human body fluids by probing with fluorescent nanoparticles coated with lectins or antibodies to known EOC associated proteins. …”
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Evaluasi Usability Aplikasi Elektronik-Kesehatan Ibu dan Anak (e-KIA) by Fitra Abdurrachman Bachtiar, Retno Indah Rokhmawati, Fajar Pradana, Intan Yusuf Habibie

“…Usability testing started by taking the literature review followed by evaluator selection and evaluation briefing. The next step is designing an evaluation instrument and evaluation scenario. …”
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Biomechanical Performance of Mandibular Molars with Deep Mesio-Occlusal-Distal Cavities Rehabilitated with Horizontal Posts: A 3D Finite Element Analysis by Sonali Sharma, Sindhu Ramesh, Jasmine Rayapudi

“…The mandibular molar models replicating the clinical scenarios were simulated, designed, and built, assuming all materials to be homogenous, isotropic, and linearly elastic as follows: Model 1 control: the model of an intact first mandibular molar. …”
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Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…The problem is approached in two distinct ways: (1) optimization of 15 designated QoIs, such as the latitude and magnitude of the African rain belt or African easterly jet, using existing surrogate models and (2) optimization of twelve 2D meteorological output fields, such as precipitation, cloud cover, and pressure, using new surrogate models that employ principal component analysis. …”
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A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes by Peter R. Johnston, Luis Quijada, Christopher A. Smith, Hans-Otto Baral, Tsuyoshi Hosoya, Christiane Baschien, Kadri Pärtel, Wen-Ying Zhuang, Danny Haelewaters, Duckchul Park, Steffen Carl, Francesc López-Giráldez, Zheng Wang, Jeffrey P. Townsend

“…Such studies will ideally include designation of epitypes for the type species of those genera for which DNA is not able to be extracted from the original type specimen, and consideration of morphological characters whenever genetically defined clades are recognized as formal taxa within a classification.…”
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Blood Meal Utilization as Organic Fe Source for Polka Dot Grouper Cromileptes altivelis Growth Performance by Mia Setiawati, P. Purnama, I. Mokoginta

“… This experiment was designed to examine the use of spray dried cell blood meal as organic Fe source in polka dot grouper (Cromileptes altivelis) feed to substitute inorganic Ferosulphate (FeSO4.7H2O). …”
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Silver-based plasmonic nanoparticles for biosensor organophosphate pesticides using a single film containing acetylcholinesterase/choline oxidase by D. Hermanto, N. Ismillayli, H. Muliasari, R. Wirawan, S.R. Kamali

“…METHODS: Biosensor organophosphate pesticides using a single film containing acetylcholinesterase/choline oxidase have been designed using silver-based plasmonic nanoparticles as a colorimetric indicator. …”
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Cultural aspects of organizational agility affecting digital innovation by Dulce Goncalves, Magnus Bergquist, Richard Bunk, Sverker Alänge

“…In this context, we find that cultural aspects are especially crucial as enablers for organizational agility in digital innovation. We designed a comparative study to investigate the differences in the influence of culture on organizational agility; and how it hinders or enables digital innovation, at both incumbent firms and startups in the automotive industry. …”
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The role of sport in research and development in Switzerland - An overview by Hippolyt Kempf, Gübeli Cornell, Christelle Ganné-Chedeville, Solange Emmenegger

“…., & Clark, V. L. (2011). Designing and conducting mixed methods research (2nd ed.). …”
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Des bidonvilles aux sites de relogement à Témara : la quête d’une identité urbaine légitime by Aziz Benkorti

“…Through a qualitative sociological survey, this article studies how the quest for a new urban identity in the Nasr neighbourhood, a collective housing project designed to rehouse former residents of Témara, has created logics of exclusion and social hierarchisation. …”
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Ultra-Wideband 4-Bit Distributed Phase Shifters Using Lattice Network at <italic>K/Ka</italic>- and <italic>E/W</italic>-Band by Sungwon Kwon, Minjae Jung, Byung-Wook Min

“…Based on our theoretical analysis, we designed the lattice network as a constant-phase shifter rather than a delay line. …”
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Exploring parenthood intentions and perceptions of infertility and assisted reproductive technology among 2SLGBTQIA + young adults in Ontario, Canada: a mixed methods study by Caitlin I. T. Ennis, Nurasha G. Fernando, Karen P. Phillips

“…Methods An online survey, designed as mixed-methods with sex-and-gender-based analysis (SGBA +), was used to recruit childless, post-secondary students, aged 18–30 years, in May–October 2022. …”
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Integrating Infant Safe Sleep and Breastfeeding Education Into an App in a Novel Approach to Reaching High-Risk Populations: Prospective Observational Study by Tamar Krishnamurti, Rachel Moon, Rudolph Richichi, Rachel Berger

“…Pregnant persons were designated as high risk if they lived in the 5% of zip codes in Allegheny County, Pennsylvania with the highest rates of SUID in the county. …”
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