Prognostic values of intracellular cell-related genes in esophageal cancer and their regulatory mechanisms by Wei Cao, Dacheng Jin, Weirun Min, Haochi Li, Rong Wang, Jinlong Zhang, Yunjiu Gou

“…Differentially expressed genes (DEGs) in ESCA samples were identified, with those related to intercellular structures designated cell-in-cell-related differential expression genes (CIC-related DEGs). …”
Get full text

Spatial identification of regions exposed to multi-hazards at the pan-European level by T.-E. Antofie, T.-E. Antofie, S. Luoni, A. Tilloy, A. Sibilia, S. Salari, G. Eklund, D. Rodomonti, C. Bountzouklis, C. Corbane

“…<p>The European Commission Disaster Risk Management Knowledge Centre (DRMKC) has developed and hosts a web platform, the Risk Data Hub (RDH), designed to facilitate access to and sharing of curated, EU-wide risk data, tools, and methodologies, ultimately supporting disaster risk management (DRM) initiatives. …”
Get full text

Hybrid Carbohydrate–Lipid Nanocarriers: In Vitro Efficacy Gene-Rated by Association of UV-Absorbers and Raspberry Polyphenols Rich-Fraction by Nicoleta Badea, Diego Samayoa, Alina Moroşan, Cristina Ott, Ioana Lacatusu

“…<b>Background/Objectives:</b> The study aims to investigate an improved version of lipid nanocarriers (NLCs) (formulated with functional coconut butter and marula oil) by designing hyaluronic acid (HA) decorated NLC co-loaded with dual UVA (butyl methoxy dibenzoyl methane, BMDBM), UVB absorbers (ethyl-hexyl-salicylate, EHS) and a Raspberry rich polyphenols fraction (RPRF) for development of more natural NLC-based to-pical formulations. …”
Get full text

Filtration and Breathability of Nonwoven Fabrics Used in Washable Masks by Thomas W. Bement, David J. Downey, Ania Mitros, Rebecca Lau, Timothy A. Sipkens, Jocelyn Songer, Heidi Alexander, Devon Ostrom, Hamed Nikookar, Steven N. Rogak

“…Sets incorporating meltblown nonwoven polypropylene designed for filtration degraded significantly post-wash in the submicron range where they excelled prior to washing (Q > 50 kPa−1 at 1 µm, respectively, degraded to Q < 10 post-wash). …”
Get full text

Application of geographical information system and remote sensing for investigating malaria’s footprint: a case study of Iwo Metropolis, Nigeria by Joseph Olajuwon Dada, Sodiq Babatunde Rajee, Wasiu Adelani Rasak, Ayodeji Olatunbosu Ajani, Ismail Abdulraheem, Olayemi Balikis Shodeinde, Ibrahim Ademola Fetuga

“…This research work was designed to examine and analyze the incidence of malaria and clearer understanding of geographic distribution of malaria-infected people and locations of such inhabitants to the health facility being essential for monitoring the prevalence and for providing treatment, care and support services to the affected area. …”
Get full text

Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial by David Evans, Francesco Negro, Michail Arvanitidis, Eduardo Martinez-Valdes, Ragul Selvamoorthy, Patricio Pincheira

“…Newly developed training protocols that employ visual feedback with specialised devices offer controlled management of loads, speeds and forces across the full range of motion, potentially providing greater benefits.Objective This protocol outlines a randomised controlled trial designed to compare the effects of a visuomotor torque feedback (TF) protocol with a traditional EE protocol on the rehabilitation of PT over a 6-week period. …”
Get full text

Study on the drying characteristics of green pellets of ultrafine iron ore concentrate by Wen B.-L., Zhang X.-P., Liu D.-L., Li J.-X., Sun X.-D., Yang J.-L.

“…This study offers theoretical support for simulating the drying of green ultrafine iron ore concentrate pellets and provides guidelines for selecting diverse drying conditions and designing drying equipment.…”
Get full text

Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…The number of research articles on DFUs has increased. This study was designed to explore the global trends and research hotspots of DFUs to benefit researchers in shaping future research directions. …”
Get full text

The Association Between Posting WeChat Moments and the Risk of Depressive Symptoms Among Middle-Aged and Older Chinese Adults: Prospective National Cohort Study by Wei Wang, Hui Wang, Xinru Hu, Qian Yu, Fangyi Chen, Xirui Qiu, Xiaoxiao Wang

“…MethodsA prospective national cohort study was designed based on the data obtained from the fourth and fifth waves of the China Health and Retirement Longitudinal Study (CHARLS). …”
Get full text

Is information provided within chronic subdural haematoma education resources adequate? A scoping review. by Conor S Gillespie, Samuel Khanna, Mark E Vivian, Samuel McKoy, Alvaro Yanez Touzet, Ellie Edlmann, Daniel J Stubbs, Benjamin M Davies

“…<h4>Results</h4>56 information resources were identified. 30 (54%) were resources designed for healthcare professionals (HCPs), and 26 (46%) were patient-orientated resources. 45 (80%) were specific to CSDH, 11 (20%) covered head injury, and 10 (18%) referenced both acute and chronic SDH. …”
Get full text

Remote work transition amidst COVID-19: Impacts on presenteeism, absenteeism, and worker well-being-A scoping review. by Behdin Nowrouzi-Kia, Alexia M Haritos, Bao-Zhu Stephanie Long, Chantal Atikian, Luke A Fiorini, Basem Gohar, Aaron Howe, Yiyan Li, Ali Bani-Fatemi

“…., working age), engaged in full or part-time work, and the employees shifted from in-person to remote work due to the COVID-19 pandemic. All study designs, geographical areas, and papers written post-onset of the COVID-19 pandemic were included; however, systematic reviews were excluded. …”
Get full text

Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes by Ye Zhang, Yanpeng Xing, Haibo Yuan, Xiaokun Gang, Weiying Guo, Zhuo Li, Guixia Wang

“…The aims of this study were to analyze clinical data of patients with OSA and evaluate influence of sleep-disordered breathing on glycometabolism and its underlying mechanisms. Methods. We designed a cross-sectional study involving 53 OSA patients in The First Hospital of Jilin University from March 2015 to March 2016. …”
Get full text

Population- and Gender-Based Investigation for Prevalence of Helicobacter pylori in Dhamar, Yemen by Dhary A. Almashhadany, Sara M. Mayas, Hero I. Mohammed, Abdulwahed A. Hassan, Izhar U. H. Khan

“…The infection can spread through direct human-to-human contact, fecal–oral route, and contaminated water. The study was designed to investigate the rate of prevalence of H. pylori in the population of Dhamar, Yemen. …”
Get full text

An alternative fixation for all mild and moderate hallux valgus cases enabling intraoperative readjustment by Mesut Uluöz, Mehmet Yiğit Gökmen, Özhan Pazarcı

“…Methods The retrospectively designed study was conducted at Adana City Training and Research Hospital, Adana, Türkiye. …”
Get full text

Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides by Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil

“…Finally, we examined how the conditions under which arthroconidia are generated influence their transcriptome and subsequent development into spherules, demonstrating that this is an important variable to control when designing spherulation experiments. Together, our data reveal multiple strategies to optimize in vitro spherulation growth, enabling characterization of this virulence-relevant morphology.IMPORTANCECoccidioides spp. are thermally dimorphic fungal pathogens found in the Southwest United States, Mexico, Central America, and South America. …”
Get full text

Development and validation of a novel bleeding risk prediction tool for aspirin users with a low body mass index by Lu Yifang, Lei Wanlin, Wang Maofeng

“…This study has successfully created a novel risk prediction tool specifically designed for aspirin users with a low BMI. This tool enables the stratification of low BMI patients based on their anticipated bleeding risk.…”
Get full text

Insights into incompatible plasmids in multidrug-resistant Raoultella superbugs by Jiao Feng, Changxin Wu, Dongsheng Zhou, Lingfei Hu, Kai Mu, Zhe Yin

“…A new incompatible group, IncFIIp23141−CTXM, was identified, alongside five newly designated Inc groups based on previously determined sequences, namely IncFIIpKPC2_EC14653, IncFIIpCP020359, IncFIIpCP024509, IncFIIpKOX−137, and IncFIIpKDO1. …”
Get full text

PortNet: Achieving lightweight architecture and high accuracy in lung cancer cell classification by Kaikai Zhao, Youjiao Si, Liangchao Sun, Xiangjiao Meng

“…Method: This paper introduces a model named PortNet, designed to significantly reduce the model's parameter size and achieve lightweight characteristics without compromising classification accuracy. …”
Get full text

Multimedia: multimodal mediation analysis of microbiome data by Hanying Jiang, Xinran Miao, Margaret W. Thairu, Mara Beebe, Dan W. Grupe, Richard J. Davidson, Jo Handelsman, Kris Sankaran

“…Despite these advances, existing software’s rigid assumptions often result in users viewing mediation analysis as a black box. We designed the multimedia R package to make advanced mediation analysis techniques accessible, ensuring that statistical components are interpretable and adaptable. …”
Get full text

Enhancing patient engagement: the influence of an in-consult patient decision aid on shared decision-making for lung tumour radiation – protocol for the randomised trial ‘SDM Lung... by Karina Dahl Steffensen, Signe Timm, Torben Frøstrup Hansen, Thomas Leth Fink, Charlotte Kristiansen, Torben Schjødt Hansen, Rune Slot Thing

“…We believe that the patients should be engaged in such a decision.To explore this matter, we have designed a randomised trial, ‘SDM Lung SBRT’, for which we present our study protocol with a special focus on a patient decision aid (PtDA), which is being tested in this trial.Methods and analysis This study includes patients with a lung tumour located ≤1 cm from the thoracic wall. …”
Get full text