Bioactive Substances in Safflower Flowers and Their Applicability in Medicine and Health-Promoting Foods by I. Adamska, P. Biernacka

“…This review is aimed at updating the state of knowledge about their applicability in oncology, pulmonology, cardiology, gynecology, dermatology, gastrology, immunology, and suitability in the treatment of obesity and diabetes and its consequences with information published mainly in 2018-2020. …”
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Successful Treatment of Annular Atrophic Lichen Planus With Adalimumab by Joe Khodeir, Paul Ohanian, Marielena Ohanian

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Huge Pyogenic Granuloma of the Penis by Fatih Akbulut, Tugba Akbulut, Faruk Kucukdurmaz, Erkan Sonmezay, Abdulmuttalip Simsek, Gokhan Gurbuz

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Lichen Striatus with Nail Involvement in a 6-Year-Old Boy by Alexander K. C. Leung, Kin Fon Leong, Benjamin Barankin

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Onychomycosis due to Cunninghamella bertholletiae in an Immunocompetent Male from Central India by Karuna Tadepalli, Pradeep Kumar Gupta, Dinesh P. Asati, Debasis Biswas

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Systemic Lupus Erythematosus Presented with Bilateral Orbital Edema and Negative Serology by Manal Al-Khaldi, Manal Alsabbagh

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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

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Międzynarodowe wytyczne EAACI/GA2LEN/EuroGuiDerm/APAAACI dotyczące definicji, klasyfikacji, diagnostyki i leczenia pokrzywki by Torsten Zuberbier, Amir Hamzah Abdul Latiff, Mohamed Abuzakouk, Susan Aquilina, Riccardo Asero, Diane R. Baker, Barbara Ballmer-Weber, Christine Bangert, Moshe Ben-Shoshan, Jonathan A. Bernstein, Carsten Bindslev-Jensen, Knut Brockow, Zenon Brzoza, Herberto Jose Chong Neto, Martin K. Church, Paulo R. Criado, Inna V. Danilycheva, Corinna Dressler, Luis Felipe Ensina, Luz Fonacier, Matthew Gaskins, Krisztian Gaspar, Aslı Gelincik, Ana Giménez-Arnau, Kiran Godse, Margarida Gonçalo, Clive Grattan, Martine Grosber, Eckard Hamelmann, Jacques Hébert, Michihiro Hide, Allen Kaplan, Alexander Kapp, Aharon Kessel, Emek Kocatürk, Kanokvalai Kulthanan, Désirée Larenas-Linnemann, Antti Lauerma, Tabi A. Leslie, Markus Magerl, Michael Makris, Raisa Y. Meshkova, Martin Metz, Daniel Micallef, Charlotte G. Mortz, Alexander Nast, Hanneke Oude-Elberink, Ruby Pawankar, Paolo D. Pigatto, Hector Ratti Sisa, Marfa Isabel Rojo Gutiérrez, Sarbjit S. Saini, Peter Schmid-Grendelmeier, Bulent E. Sekerel, Frank Siebenhaar, Hanna Siiskonen, Angele Soria, Petra Staubach-Renz, Luca Stingeni, Gordon Sussman, Andrea Szegedi, Simon Francis Thomsen, Zahava Vadasz, Christian Vestergaard, Bettina Wedi, Zuotao Zhao, Marcus Maurer

“…Jest to wspólna inicjatywa Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), Global Allergy and Asthma European Network (GA2LEN) i jej Urticaria and Angioedema Centers of Reference and Excellence (UCAREs i ACAREs), European Dermatology Forum (EDF; EuroGuiDerm) oraz Asia Pacific Association of Allergy, Asthma and Clinical Immunology z udziałem 64 delegatów z 50 towarzystw krajowych i międzynarodowych z 31 krajów. …”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

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Clinical outcomes and adverse events of Hedgehog pathway inhibitors for advanced basal cell carcinoma patients: A systematic review and meta-analysis by Suvijak Untaaveesup, Wichapol Dendumrongsup, Pornteera Srichana, Chanamon Pongphaew, Gynna Techataweewan, Kanmanee Viratkapan, Nichanant Nampipat, Ben Ponvilawan, Chayanis Kositamongkol, Walaiorn Pratchyapruit, Pochamana Phisalprapa

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Rapid Verbal Persuasion to increase influenza vaccine uptake: protocol for a randomized hybrid type 2 effectiveness -implementation trial by Siyuan Liu, Lan Gao, Yingying Jin, Jiangyun Chen, Dadong Wu, Yiyuan Cai, Tao Wang, Sanhao Huang, Ciling Yan, Run Wang, Dong Roman Xu

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MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma by Camille Niveau, Mélanie Cettour-Cave, Stéphane Mouret, Eleonora Sosa Cuevas, Mylene Pezet, Benoît Roubinet, Hugo Gil, Florence De Fraipont, Ludovic Landemarre, Julie Charles, Philippe Saas, Caroline Aspord

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Shaping Treatment Expectation to Optimize Efficacy of Interleukin 17A Antagonist Secukinumab in Psoriasis Patients by Hölsken S, Krefting F, Mühlhaus S, Bese D, Schedlowski M, Sondermann W

“…We evaluated skin symptoms using the Psoriasis Area and Severity Index (PASI), the Dermatology Life Quality Index (DLQI), perceived itch, mood and plasma IL-17A levels at baseline and at 1, 2, 3, 4, 8, 12, and 16 weeks post intervention.Results: The study included N = 120 patients (average age = 45.78 years, 34% female). …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…Qiao Wang,1,* Xin Luo,1,* Yuwen Su,1 Yi Jin,1 Qiqi Kuang,1 Siying Li,1 Weiyun Shen,2 Yanshan Zhu1 1Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Anesthesiology, Second Xiangya Hospital, Anesthesiology Research Institute of Central South University, Changsha, Hunan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Luo; Yanshan Zhu, Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China, Email 248201037@csu.edu.cn; 218202091@csu.edu.cnBackground: Psoriasis is an immune-related inflammatory systemic condition characterized by dysregulated keratinocyte proliferation and chronic inflammation. …”
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Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study by Johan Burisch, Lene Terslev, Mikkel Østergaard, Annette Bøjer Jensen, Frank Krieger Jensen, Flemming Bendtsen, Charlotte Wiell, Mohamed Attauabi, Klaus Theede, Viktoria Fana, Hartwig Roman Siebner, Henrik S Thomsen, Jakob M Møller, Simon Francis Thomsen, Gorm Roager Madsen, Anne Vibeke Wewer, Rune Wilkens, Johan Ilvemark, Nora Vladimirova, Sanja Bay Hansen, Yousef Jesper Wirenfeldt Nielsen, Helene Andrea Sinclair Ingels, Trine Boysen, Jacob T Bjerrum, Christian Jakobsen, Maria Dorn-Rasmussen, Sabine Jansson, Yiqiu Yao, Ewa Anna Burian, Frederik Trier Møller, Kristina Bertl, Andreas Stavropoulos, Jakob B Seidelin

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The causal relationship between serum metabolites and the risk of psoriasis: a Mendelian randomization and meta-analysis study by Yujie Yang, Xuwei Zheng, Haiying Lv, Bin Tang, Bin Tang, Bin Tang, Bin Tang, Bin Tang, Yiyuan Zhong, Qianqian Luo, Yang Bi, Kexin Yang, Haixin Zhong, Haiming Chen, Haiming Chen, Haiming Chen, Haiming Chen, Haiming Chen, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu

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Large Rhinophyma Treated by Surgical Excision and Electrocautery by Nabeel K. Al Hamzawi, Salih M. Al Baaj

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Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata by Taisuke Ito

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Macrolides in Chronic Inflammatory Skin Disorders by Abdullateef A. Alzolibani, Khaled Zedan

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Subcutaneous Emphysema and Severe Interstitial Lung Disease in the Setting of Anti-MDA 5 Positive Dermatomyositis in a Hispanic Patient by Sweta Subhadarshani, Brad Woodie, Emerson Bookal, Justin Reed

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