-
301
Mesenchymal Stem Cells Attenuate Cisplatin-Induced Nephrotoxicity in iNOS-Dependent Manner
Published 2017-01-01“…MSC treatment significantly attenuated influx of leukocytes, macrophages, dendritic cells (DCs), neutrophils, CD4+ T helper (Th), and CD8+ cytotoxic T lymphocytes (CTLs) in damaged kidneys and attenuated the capacity of renal-infiltrated DCs, CD4+ Th, and CD8+ CTLs to produce TNF-α and IL-17. …”
Get full text
Article -
302
Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice
Published 2025-02-01“…In vitro results indicated that exosomes could be internalized by dendritic cells (DCs), promote DC differentiation, and subsequently induce the production of granzyme B and IFN-γ in T cells. …”
Get full text
Article -
303
Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats
Published 2025-01-01“…In the microenvironment, macrophages had an increased number of interactions with hepatocytes, myofibroblasts, T cells, neutrophils, and dendritic cells, while their interaction strengths remained unchanged. …”
Get full text
Article -
304
Association between changes in genital immune markers and vaginal microbiome transitions in bacterial vaginosis
Published 2025-01-01“…Improvement correlated with decreased monocytes (p = 0.005), while worsening was linked to increased monocytes (p < 0.001) and dendritic cells (p = 0.02). B cells (p = 0.02) and IFN-γ-induced chemokines - IP-10 (p = 0.007), MIG (p = 0.049), and ITAC (p = 0.005) - were associated with improvement. …”
Get full text
Article -
305
Identification of mitophagy-related biomarkers and immune infiltration in polycystic ovarian syndrome by bioinformatic study
Published 2025-02-01“…Specifically, the hub gene GRN showed a positive correlation with monocytes and plasmacytoid dendritic cells, while hub gene NAPA was negatively correlated with gamma delta T cell. …”
Get full text
Article -
306
IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome
Published 2019-01-01“…It is caused by the interaction between inflammatory cells such as macrophages, dendritic cells, and lipoproteins. Evidence has revealed that macrophage pyroptosis in lesion contributes to the formation of the necrotic core and thinning of the fibrous cap, which plays crucial roles in the onset of acute coronary syndrome (ACS). …”
Get full text
Article -
307
Exosome-Associated Gene Signature for Predicting the Prognosis of Ovarian Cancer Patients
Published 2023-01-01“…We discovered that resting dendritic cells and stromal scores were upregulated in patients with high risk in the TCGA and Gene Expression Omnibus (GEO) cohorts. …”
Get full text
Article -
308
Peptide Antigen Modifications Influence the On-Target and Off-Target Antibody Response for an Influenza Subunit Vaccine
Published 2025-01-01“…The PAMs were characterized, then their immunogenicity was evaluated with bone marrow-derived dendritic cells and in mice. Results: Although the modification scheme yielded immunogenic PAMs, these PAMs induced a substantial amount of off-target antibody production compared to unmodified peptidyl micelles (PMs, M2<sub>1–24</sub> peptide). …”
Get full text
Article -
309
Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity
Published 2025-02-01“…This was associated with an increased infiltration of macrophages, CXCR3 expressing CD8 T cells, and monocytic myeloid-derived suppressor cells (M-MDSCs) with a concomitant decrease in numbers of dendritic cells (DCs), in the AT of siglec-E KO fed HFD versus the WT HFD counterparts. …”
Get full text
Article -
310
Differential T cell accumulation within intracranial and subcutaneous melanomas is associated with differences in intratumoral myeloid cells
Published 2024-11-01“…Surprisingly, we found no evidence for T cell activation in draining lymph nodes of SC or IC tumor-bearing mice, consistent with the fact that dendritic cells (DC) that had acquired tumor antigen showed an immature phenotype. …”
Get full text
Article -
311
Interleukin‐37 promotes DMBA/TPA skin cancer through SIGIRR‐mediated inhibition of glycolysis in CD103+DC cells
Published 2023-04-01“…Here, we report that IL‐37b‐transgenic mice (IL‐37tg) treated with the carcinogenic 7,12‐dimethylbenzoanthracene (DMBA)/12‐o‐tetradecylphorbol‐13‐acetate (TPA) exhibited enhanced skin cancer and increased tumor burden in the skin by inhibiting the function of CD103+ dendritic cells (DCs). Notably, IL‐37 induced rapid phosphorylation of adenosine 5‘‐monophosphate (AMP)‐activated protein kinase (AMPK), and via single immunoglobulin IL‐1‐related receptor (SIGIRR), inhibited the long‐term Akt activation. …”
Get full text
Article -
312
Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study
Published 2025-02-01“…Early research primarily focused on angiogenesis, dendritic cells, and expression markers, while recent trends have shifted towards phase III trials, adverse reactions, and checkpoint inhibitors, underscoring the field’s dynamic progression.ConclusionFuture research will expand on the pathological mechanisms underlying these therapies and novel interventions and combination strategies. …”
Get full text
Article -
313
Peripheral Regulatory Cells Immunophenotyping in Kidney Transplant Recipients with Different Clinical Profiles: A Cross-Sectional Study
Published 2012-01-01“…Regulatory Foxp3-expressing T cells (Tregs), IL-10-producing B cells (Bregs), and IDO-expressing dendritic cells (DCregs) downregulate inflammatory processes and induces peripheral tolerance. …”
Get full text
Article -
314
Chemotherapy in synergy with innate immune agonists enhances T cell priming for checkpoint inhibitor treatment in pancreatic cancer
Published 2025-01-01“…Adding chemotherapy to innate agonists enhances the infiltration of dendritic cells (DCs) in the tumors and CD86+ mature DCs in tumor draining lymph nodes. …”
Get full text
Article -
315
M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity
Published 2025-01-01“…In addition, BLPs-SAM-FAdE can effectively target M cell models and M cells of mouse Peyer’s patches (PPs) through oral immunization, promote the transport of particulate vaccines to dendritic cells (BMDCs) and stimulate their maturation, significantly increased proportion of plasma cells and germinal centers B cells. …”
Get full text
Article -
316
Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis
Published 2017-01-01“…An increased depletion of B and T lymphocytes, NKT cells, dendritic cells, and macrophages was observed 48 h postinfection (PI) in IL-33 KO mice than that in WT mice. …”
Get full text
Article -
317
Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma
Published 2018-01-01“…Dendritic cells (DCs) harboring tumor-associated antigen are supposed to be a potential immunotherapy for hepatocellular carcinoma (HCC). …”
Get full text
Article -
318
Immunomodulatory Effects of Aerobic Training in Obesity
Published 2011-01-01“…Methods. Circulating dendritic cells (DC) were analyzed by flow-cytometry for BDCA-1/-2-expression. …”
Get full text
Article -
319
Comprehensive Analysis of PDLIM3 Expression Profile, Prognostic Value, and Correlations with Immune Infiltrates in Gastric Cancer
Published 2022-01-01“…Furthermore, increased PDLIM3 expression was significantly correlated with greater infiltration of CD4+ T cells, CD8+ T cells, macrophages, neutrophils, and dendritic cells. PDLIM3 expression had significant positive correlations with a variety of immune marker subsets. …”
Get full text
Article -
320
The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways
Published 2025-01-01“…In this study, we first tested the effect of hAAT on TLR9 signaling in dendritic cells (DCs). We showed that hAAT inhibited TLR9-mediated DC activation and cytokine production. …”
Get full text
Article