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241
Exploring the Crosstalk between Inflammation and Epithelial-Mesenchymal Transition in Cancer
Published 2021-01-01“…EMT drives primary tumors to metastasize in different parts of the body. T and B cells, dendritic cells (DCs), and tumor-associated macrophages (TAMs) which are present in the tumor microenvironment induce EMT. …”
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242
Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality
Published 2025-01-01“…Metastatic TNBC (mTNBC) patients had reduced T cells, dendritic cells, and differentiated B cells compared to non-metastatic TNBC patients and HDs, partly linked to prior chemotherapy. …”
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243
Regulatory Role of CD4+ T Cells in Myocarditis
Published 2018-01-01“…In the presence of tissue damage and innate immune activation, however, activated self-antigen-loaded dendritic cells promote CD4+ effector T cell expansion and myocarditis. …”
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244
Interstitial Mycosis Fungoides: An Unusual Mimic of Interstitial Granuloma Annulare Not to Miss
Published 2022-01-01“…Mixed in the dermis with the atypical lymphoid cells were a few CD68 positive histiocytes and S100 protein positive dermal dendritic cells. T-cell receptor beta gene rearrangement studies showed nearly the same clonal peaks for TCRB rearrangement in two biopsy specimens from separate sites, all supporting a diagnosis of interstitial mycosis fungoides. …”
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245
The Role of the Immune System in Huntington’s Disease
Published 2013-01-01“…As part of the adaptive immune system, dendritic cells (DCs) prime T-cell responses secreting inflammatory mediators. …”
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246
Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells
Published 2015-01-01“…This review will focus on Mtb interactions with human macrophages, dendritic cells, neutrophils, and NK cells and detail evidence that Mtb modulation of these cells negatively impacts Mtb-specific immune responses. …”
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247
The Role of NK Cells in Pig-to-Human Xenotransplantation
Published 2017-01-01“…The potential of cell-based strategies including tolerogenic dendritic cells (DC) and regulatory T cells (Treg) and the latest progress using transgenic pigs genetically modified to reduce xenogeneic NK cell responses are discussed. …”
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248
Mannan-decorated STING-activating vaccine carrier for spatial coordinative stimulating antigen-specific immune responses
Published 2025-01-01“…Mannan-decoration as the shell could significantly enhance the lymph node draining ability of the nanovaccines, especially in CD8+ dendritic cells (DCs). Azole molecule end-capped polylactic acid-polyethylenimine (PLA-PEI-4BImi) with innate stimulating activity was applied as the inner core for coordinating antigen-presenting cell activation and antigen cross-presentation. …”
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249
Tissue‐resident memory T cells in diseases and therapeutic strategies
Published 2025-01-01“…We also explore the interactions of TRM cells with other immune cells, such as B cells, macrophages, and dendritic cells, highlighting the complex network that underpins the efficacy of TRM cells in immune surveillance and response. …”
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250
The Role of Myeloid Cells on the Development of Hepatic Metastases in Gastrointestinal Cancer
Published 2025-01-01“…We further summarize the role of additional myeloid subpopulations such as monocytes and macrophages, dendritic cells, platelets, and eosinophils on promoting disease metastases in GI cancers. …”
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251
Manganese-pyrochloric acid photosensitizer nanocomplexes against osteosarcoma: achieving both high activatability and high effectiveness
Published 2025-02-01“…Additionally, Mn2+ ions activated the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, promoting maturation of dendritic cells (DCs) and augmenting CD8+-mediated antitumor immune responses.DiscussionThis study advances the on-demand activation of photosensitive drugs and photodynamic immunotherapy toward clinical applicability by exploiting Mn2+–PPa nanocomplexes with high activatability and effectiveness for targeted PDT and immunotherapy.…”
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252
A dynamic peripheral immune landscape during human pregnancy
Published 2025-01-01“…Moreover, the transition from adaptive immune reduction to activation in late pregnancy in dendritic cells and CD4+ T cells was also detected. Notably, we proposed a novel view of the pro-aging effect of pregnancy from the perspective of immunity, and this effect may be restored postpartum. …”
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253
Innate immune cells in vascular lesions: mechanism and significance of diversified immune regulation
Published 2025-12-01“…This review focuses on innate immune cells and mainly introduces the regulatory mechanisms of monocytes, macrophages, natural killer (NK) cells, dendritic cells (DCs) and neutrophils in vascular lesions. …”
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254
Single-cell transcriptomics unveils multifaceted immune heterogeneity in early-onset versus late-onset cervical cancer
Published 2025-01-01“…Macrophages in LOCC displayed enhanced polarization towards both M1 and M2 phenotypes, along with dendritic cells showing augmented antigen-presenting capacity. …”
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255
Potential and development of cellular vesicle vaccines in cancer immunotherapy
Published 2025-01-01“…DEVs play a role in amplifying the immune response by acting as carriers for the dissemination of antigenic substances in dendritic cells. OMVs, with their natural adjuvant properties, are one of the advantages for the preparation of antitumor vaccines. …”
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256
Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells
Published 2019-01-01“…The cytokines subsequently recruit subsets of immune cells appropriate to a particular immune context and response, such as dendritic cells (DCs), T, B, and natural killer (NK) cells. …”
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257
Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2...
Published 2006-01-01“…Indeed, NK cells can kill and produce pro-inflammatory and regulating cytokines as IFN-γ, TNF-α and IL10 during interaction with autologous dendritic cells or bone marrow stromal cells or skin fibroblasts. …”
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258
The Role of PPARs in Placental Immunology: A Systematic Review of the Literature
Published 2013-01-01“…Both the innate and the adaptive immune system, and therefore B and T lymphocytes, natural killer cells (NK), macrophages and dendritic cells (DCs) are all involved in trophoblast invasion, pregnancy maintenance, and development of pregnancy disorders. …”
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259
Mathematical insights on psoriasis regulation: Role of Th1 and Th2 cells
Published 2018-05-01“…Psoriasis is an autoimmune disorder, characterized by hyper-proli-feration of Keratinocytes for the abnormal activation of T Cells, Dendritic Cells (DCs) and cytokine signaling. Interaction of DCs and T Cells enable T Cell to differentiate into Type 1 (Th1), Type 2 (Th2) helper T Cell depending on cytokine release. …”
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260
Nanoparticles Modulating the Immune Microenvironment in Breast Cancer Treatment
Published 2025-02-01“…We then provide strategies of nanoparticles for targeting immune cells such as macrophages, dendritic cells, and T-cells. The role of nanoparticles in enhancing immune checkpoint blockade (ICB) and their application in cancer vaccines is also examined. …”
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