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781
Experimental study of cognitive function against the background of partial food derivation and its correction
Published 2023-06-01“…Metabolic disorders such as obesity are known to adversely affect cognitive function and may even lead to dementia. But it is still unknown how food deprivation affects the cognitive function of rats, as well as the ability of animals to cope with stressful situations, because hunger is one of the models of stressors. …”
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782
Sicca Symptoms in Parkinson’s Disease: Association with Other Nonmotor Symptoms and Health-Related Quality of Life
Published 2020-01-01“…Autonomic symptoms (Survey of Autonomic Symptoms, SASs), motor function (Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale III, MDS-UPDRS III), nonmotor symptoms (nonmotor symptoms questionnaire, NMS-Quest), and QoL (PD Questionnaire-39, PDQ-39) were analysed in 93 PD patients without dementia. Multivariable and multivariate analyses were performed to study the association between clinical parameters and PDQ-39 domains. …”
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783
Subthalamic Nucleus Deep Brain Stimulation in Early Stage Parkinson’s Disease Is Not Associated with Increased Body Mass Index
Published 2017-01-01“…This study analyzes changes in body mass index (BMI) in 29 subjects from a prospective, single-blind trial of DBS in early stage PD (age 50–75, Hoehn & Yahr stage II off medication, treated with antiparkinsonian medications for ≥6 months but <4 years, and without a history of motor fluctuations, dyskinesias, or dementia). Subjects were randomized to DBS plus optimal drug therapy (DBS+ODT; n=15) or ODT (n=14) and followed for 24 months. …”
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784
Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association...
Published 2025-12-01“…Background Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.Methods Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine endorses this position paper with recommendations to prevent RSV-associated disease and its complications in adults through vaccination.Conclusion The RSV vaccine is recommended for people aged ≥50 years with risk factors (chronic obstructive pulmonary disease, asthma, heart failure, coronary artery disease, diabetes, chronic kidney disease, chronic liver disease, immunocompromise, frailty, dementia, and residence in a nursing home) and all persons aged ≥60 years. …”
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785
Glymphatic system: a self-purification circulation in brain
Published 2025-02-01“…Damage to the glymphatic system will give rise to the development and progression of many brain diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), chronic traumatic encephalopathy (CTE), and vascular dementia (VaD). Here, we reviewed previous research associated with the glymphatic system, including its concepts, principles, and influencing factors. …”
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786
Research Progress and Trends in Exercise Interventions for Mild Cognitive Impairment: A Bibliometric Visualization Analysis Using CiteSpace
Published 2025-01-01“…High co-occurrence keywords include “mild cognitive impairment”, “dementia”, and “Alzheimer’s disease”. The primary keyword clusters are #0 Cognitive training, #1 Cognitive impairment, and #2 Mild Cognitive impairment, while newly burst keywords “systematic review”, “recommendations”, and “depression”.Conclusion: Research on exercise interventions for MCI has been steadily gaining attention, becoming an interdisciplinary research area in fields such as geriatrics and neuroscience, with relevant findings concentrated in specific journals. …”
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787
Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community
Published 2024-08-01“…The cognitive function of the subjects was evaluated by P-GPCOG, the Montreal Cognitive Assessment (MoCA), and the 8-item ascertain dementia (AD8). The independence of daily living ability was evaluated by the Lawton Instrumental Activities of Daily Living Scale (IADLs). …”
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788
Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology
Published 2013-01-01“…The role of biomarkers in predicting pathological findings in the frontotemporal dementia (FTD) clinical spectrum disorders is still being explored. …”
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789
Addenbrooke’s Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson’s Disease
Published 2015-01-01“…The main aim of this study was to verify the sensitivity and specificity of Addenbrooke’s Cognitive Examination-Revised (ACE-R) in discriminating between Parkinson’s disease (PD) with normal cognition (PD-NC) and PD with mild cognitive impairment (PD-MCI) and between PD-MCI and PD with dementia (PD-D). We also evaluated how ACE-R correlates with neuropsychological cognitive tests in PD. …”
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790
Recipient and instructor perspectives of an adapted exercise-based fall prevention programme for adults aged 50+ years with vision impairment: a qualitative study nested within a r...
Published 2020-09-01“…The 154 recipients interviewed were community-dwelling adults aged ≥50 years with vision impairment and no diagnosis of dementia, and had completed their participation in the programme as part of the intervention group of the RCT.Results Six key themes were identified relating to recipient (delivery aptitude, social norms, habit formation) and instructor (individualised adaptation, complimentary to scope of practice, challenges to delivery) perspectives. …”
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791
Parkinson’s Disease Prediction: An Attention-Based Multimodal Fusion Framework Using Handwriting and Clinical Data
Published 2024-12-01“…This degeneration manifests as cognitive decline, movement impairment, and dementia. Our focus in this investigation is on PD, a neurodegenerative disorder characterized by the loss of dopamine-producing neurons in the brain, leading to motor disturbances. …”
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792
Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion
Published 2019-01-01“…Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. …”
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793
Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances
Published 2022-09-01“…Patients with T2DM suffer from complications such as the development of a chronic hyperglycemic condition and even serious metabolic disorders and organ damage in the body and depression and dementia, in addition to other chronic complications. …”
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794
Uncontrolled hypertension among adult hypertensive patients in Addis Ababa public hospitals: A cross-sectional study of prevalence and associated factors.
Published 2024-01-01“…Uncontrolled hypertension can cause stroke, myocardial infarction, heart failure, renal failure, dementia, blindness, and death. However, most of the studies used the previous seventh joint national committee classification to classify hypertensive patients as either controlled or uncontrolled. …”
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795
Multimodal feature fusion-based graph convolutional networks for Alzheimer's disease stage classification using F-18 florbetaben brain PET images and clinical indicators.
Published 2024-01-01“…Alzheimer's disease (AD), the most prevalent degenerative brain disease associated with dementia, requires early diagnosis to alleviate worsening of symptoms through appropriate management and treatment. …”
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796
Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study
Published 2025-01-01“…A validated questionnaire of Healthy Aging Instruments (HAI), Basic Psychological Needs Satisfaction (BPNS), Patient Health Questionnaire (PHQ-9), Ascertain Dementia 8 questionnaire (AD8), Family Adaption Scale (FAS), Community-Based Health Promotion Activity Questionnaires (HPAQ), Social Function Questionnaire for Chinese Older Adults (SFQCOA), Adult Health Self-Management Skills (ability) Rating Scale (AHSMSRS) was incorporated. …”
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797
Research hotspots and trends in the antioxidant effects of acupuncture: A bibliometric analysis from 2003 to 2024
Published 2025-03-01“…Neurological disorders such as Parkinson's disease, vascular dementia, and stroke are major research areas in this field. …”
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798
Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review
Published 2025-01-01“… Objective Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. The aim of this review is to assess the impact of different types and intensities of physical exercise on cognitive functions, biomarkers, and the quality of life of AD patients. …”
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799
Inflammatory biomarkers profiles and cognition among older adults
Published 2025-01-01“…We explored 23 circulating inflammatory biomarkers using data from 1,743 participants without dementia (≥ 65 years-old) from the community-based, multiethnic Washington Heights Inwood Columbia Aging Project. …”
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800
Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature.
Published 2023-01-01“…., end-stage cancer, dementia), with a number of studies suggesting possible benefits while others found no benefit. …”
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