Climate change and neurological diseases: report from the Hot Brain 2: Climate Change and Brain Health meeting, 2024 by Sanjay M Sisodiya, Shakoor Hajat, Oliver Jones, Derk-Jan Dijk, Marina Romanello, Lisa Page, Jason Berwick, Kristie Ebi, Susan Clayton, Medine I Gulcebi, Candice Howarth, James D Mills, Jo Allatt, Action Amos, Jack Atkinson, Kimberly C Doell, Candace C Fleischer, Mark Maslin, Lisa Vanhala

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MRI imaging characteristics of brainstem and midbrain aqueduct in patients with iNPH by Kui Xiao, Liangxue Zhou, Xielin Tang, Shenghua Liu, Ziang Deng, Feilong Yang

“…Abstract Idiopathic normal pressure hydrocephalus (iNPH) is frequently difficult to diagnose due to the absence of specific symptoms, yet early detection and surgical intervention are essential for preventing sequela such as irreversible dementia. This study explores the specific magnetic resonance imaging (MRI) features of the brainstem and mesencephalic aqueduct in patients with iNPH. …”
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Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence by Patrycja Kozubek, Julia Kuźniar, Magdalena Czaja, Hanna Sitka, Urszula Kochman, Jerzy Leszek

“…Recently research has been focused on the effect of human endogenous retroviruses on the development of neurodegenerative diseases, including Alzheimer’s disease (AD), which is the most common cause of dementia. AD is also linked to a significant deterioration in quality of life. …”
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Possible influence of sex on the relationship between dual-task gait costs and cognitive decline in older adults. by Monica Christova, Shane Fresnoza, Christoph Palli, Wolfgang Staubmann, Bernhard Guggenberger

“…These underwent Cognitive Functional Dementia (CFD) testing to determine their cognitive abilities and DTG testing to evaluate their gait parameters (gait speed, cadence, stride length, stride variance, and stance phase duration) while performing a backward serial number counting task. …”
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Analyzing the potential of neuronal pentraxin 2 as a biomarker in neurological disorders: A literature review by Ubaid Ansari, Jimmy Wen, Burhaan Syed, Dawnica Nadora, Romteen Sedighi, Denise Nadora, Vincent Chen, Forshing Lui

“…Furthermore, NP2's involvement in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) emphasizes its broad impact on neuronal health. …”
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Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors by Shashank Shekhar, Charles Tracy, Peter V. Lidsky, Raul Andino, Katherine J. Wert, Helmut Krämer

“…Abstract Sensory disabilities have been identified as significant risk factors for dementia but underlying molecular mechanisms are unknown. …”
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A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset by Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák

“…Creutzfeldt-Jakob disease (CJD) is an untreatable rare human prion disease characterized by rapidly progressive dementia along with various neurological features, including myoclonus and sometimes other movement disorders. …”
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Peripheral proteinopathy in neurodegenerative diseases by Bin Xu, Xia Lei, Ying Yang, Jiayi Yu, Jun Chen, Zhi Xu, Keqiang Ye, Jing Zhang

“…Abstract Proteinopathies in neurology typically refer to pathological changes in proteins associated with neurological diseases, such as the aggregation of amyloid β and Tau in Alzheimer’s disease, α-synuclein in Parkinson’s disease and multiple system atrophy, and TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal dementia. Interestingly, these proteins are also commonly found in peripheral tissues, raising important questions about their roles in neurological disorders. …”
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Acquired Localized Hypertrichosis Induced by Rivastigmine by Adrian Imbernón-Moya, Sebastian Podlipnik, Fernando Burgos, Elena Vargas-Laguna, Antonio Aguilar-Martínez, Eva Fernández-Cogolludo, Miguel Angel Gallego-Valdes

“…Rivastigmine is a reversible and competitive inhibitor of acetylcholinesterase and butyrylcholinesterase used for symptomatic treatment of Alzheimer dementia and Parkinson’s disease. It has an adequate safety profile and cutaneous side effects are unusual. …”
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Synthesis, docking, pharmacokinetic prediction, and acetylcholinesterase inhibitory evaluation of N-(2-(piperidine-1-yl)ethyl)benzamide derivatives as potential anti-Alzheimer agen... by Ahmad Mohammadi-Farani, Farzaneh Moradi, Amin Hosseini, Alireza Aliabadi

“…Background and purpose: Alzheimer’s disease is the most common form of dementia and the sixth most common cause of death in the US according to the Alzheimer’s Association. …”
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Multivariate Analyses with Two-Step Dimension Reduction for an Association Study Between ¹¹C-Pittsburgh Compound B and Magnetic Resonance Imaging in Alzheimer’s Disease... by Atsushi Kawaguchi, Fumio Yamashita

“…Our method may facilitate the development of a dementia biomarker from brain imaging data. Scoring imaging data allows for visualization and the application of traditional analysis, facilitating clinical analysis for better interpretation of results.…”
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Second-generation anti-amyloid monoclonal antibodies for Alzheimer’s disease: current landscape and future perspectives by Byeong-Hyeon Kim, Sujin Kim, Yunkwon Nam, Yong Ho Park, Seong Min Shin, Minho Moon

“…Abstract Alzheimer’s disease (AD) is the most common type of dementia. Monoclonal antibodies (MABs) serve as a promising therapeutic approach for AD by selectively targeting key pathogenic factors, such as amyloid-β (Aβ) peptide, tau protein, and neuroinflammation. …”
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Consultations on driving in people with cognitive impairment in primary care: A scoping review of the evidence. by Carol Sinnott, Tony Foley, Justin Forsyth, Kathleen McLoughlin, Linda Horgan, Colin P Bradley

“…<h4>Participants</h4>PCPs or their equivalent and/ or individuals with cognitive impairment across the spectrum of mild cognitive impairment to dementia.<h4>Measurements</h4>Systematic search of Medline, Cinahl, PsychINFO, Academic Search Complete, Psychological and Behavioural Sciences Collection, SocIndex and Social Sciences FT were conducted. …”
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Relationship between social determinants of health and cognitive performance in an older American population: a cross-sectional NHANES study by Zhen-Guo Yang, Xu Sun, Xue Han, Xiao Wang, Lei Wang

“…Actively investigating the relationship between these factors may be a crucial strategy for delaying dementia onset.…”
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Dietary Fatty Acids and Predementia Syndromes by Vincenzo Solfrizzi, Vincenza Frisardi, Cristiano Capurso, Alessia D' Introno, Anna M. Colacicco, Gianluigi Vendemiale, Antonio Capurso, Francesco Panza

“…Therefore, at present, no definitive dietary recommendations on fish and unsaturated fatty acids consumption, or lower intake of saturated fat, in relation to the risk for dementia and cognitive decline are possible.…”
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Transformative Service Research and the role of service robots: a bibliometric analysis by Priscila Pasti Barbosa, Felipe Facco Mendes Ferreira, Larissa Cayla Cesário, Glauco Henrique de Souza Mendes

“…The analysis of several use cases of service robots in elderly care is carried out in the article to highlight the importance of using this service in cases of great importance, such as in cases of dementia. Cultural sensitivity and personalization of robots emerged as essential factors for increasing user acceptance and scalability, particularly in diverse healthcare environments. …”
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Estimating the potential health effects of cleaner air in the initial stages of the COVID-19 pandemic: a study in Malmö, Sweden by Ebba Malmqvist, Emilie Stroh, Erin Flanagan, Christina Isaxon, Pontus Roldin, Anna Oudin

“…If sustained, such improvements could lead to an estimated 1–3% decrease in premature deaths, a 2% decrease in preeclampsia cases, a 6% decrease in low birthweight children, a 4% decrease in bronchitis cases among children, a 2% decrease in asthma cases, a 0.2% decrease in hospital admissions for respiratory diagnoses, and an estimated 11% decrease in dementia cases annually. Conclusion The findings illustrate the potential for enhanced health in Malmö due to improved air quality. …”
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Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions by Grace Kuo, Ramhari Kumbhar, William Blair, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao

“…Abstract α-Synucleinopathies constitute a spectrum of neurodegenerative disorders, including Parkinson’s disease (PD), Lewy body dementia (LBD), Multiple System Atrophy (MSA), and Alzheimer’s disease concurrent with LBD (AD-LBD). …”
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Impact of Alzheimer’s Disease on Caregivers in the United States by Megan Vu, Rohan Mangal, Thor Stead, Carlos Lopez-Ortiz, Latha Ganti

“…As patients’ symptoms of dementia continue to worsen, they gradually grow more limited in their independence. …”
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Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review by Cyrus Jalili, Amir Kiani, Mohammadreza Gholami, Fariborz Bahrehmand, Sajad Fakhri, Somayeh Kakehbaraei, Seyran Kakebaraei

“…Abstract Alzheimer's disease (AD) is one of the chief neurological difficulties in the aged population, identified through dementia, memory disturbance, and reduced cognitive abilities. β‐amyloid (Aβ) plaques aggregations, generation of reactive oxygen species, and mitochondrial dysfunction are among the major signs of AD. …”
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