Using Health Utility Index (HUI) for Measuring the Impact on Health-Related Quality of Life (HRQL) Among Individuals with Chronic Diseases by Frank Mo, Bernard C.K. Choi, Felix C.K. Li, Joav Merrick

“…Urinary incontinence, Alzheimer/other dementia, effects of stroke, cancers, thyroid condition, and back problems have a moderate impact. …”
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Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease by Geetika Nehra, Bryan J. Maloney, Rebecca R. Smith, Wijitra Chumboatong, Erin L. Abner, Peter T. Nelson, Björn Bauer, Anika M. S. Hartz

“…Methods We used postmortem brain tissue and plasma samples from 19 participants: 9 CNI and 10 AD dementia patients who had come to autopsy from the University of Kentucky AD Research Center (UK-ADRC) community-based cohort; all cases with dementia had confirmed severe ADNC. …”
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Presence and Absence in Margaret Atwood’s Dearly by Pilar Sánchez-Calle

“…Many of these poems are dedicated to her partner Graeme Gibson, who was diagnosed with vascular dementia in 2017 and passed away in 2019. Through close readings and formal analysis, I aim to demonstrate how these elegiac poems articulate a psychic landscape of mourning where separation after death is rejected and an alternative space for reunion with the deceased is created. …”
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A Case of Tick-Borne Paralysis in a Traveling Patient by Kevin Ha, Kathryn Lewis, Vandan Patel, Jennifer Grinceri

“…An 88-year-old man with dementia and dyslipidemia presented with new onset gait instability and was admitted for suspected cerebellar stroke. …”
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Potential Synergies of β-Hydroxybutyrate and Butyrate on the Modulation of Metabolism, Inflammation, Cognition, and General Health by Franco Cavaleri, Emran Bashar

“…The low-carbohydrate high-fat diet (LCHFD), also known as the ketogenic diet, has cycled in and out of popularity for decades as a therapeutic program to treat metabolic syndrome, weight mismanagement, and drug-resistant disorders as complex as epilepsy, cancer, dementia, and depression. Despite the benefits of this diet, health care professionals still question its safety due to the elevated serum ketones it induces and the limited dietary fiber. …”
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Uma carta para Mark Freeman sobre a “promessa trágica” de doenças neurodegenerativas by Will Lucas Silva Pena

“…Nela, debato elementos que o autor traz em seu artigo Beyond narrative: dementia’s tragic promise (2008a), em especial a associação entre “narrativas”, “subjetividade” e “processos de adoecimento”. …”
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Clinical Interaction between Brain and Kidney in Small Vessel Disease by Masaki Mogi, Masatsugu Horiuchi

“…Recently, changes in the vascular system of the brain have been shown to contribute to the onset and progression of cognitive impairment, not only vascular dementia but also Alzheimer's disease. Patients with CKD are also reported to have higher risk of impaired cognitive function in the future compared with non-CKD subjects. …”
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Role of Neuroinflammation in Adult Neurogenesis and Alzheimer Disease: Therapeutic Approaches by Almudena Fuster-Matanzo, María Llorens-Martín, Félix Hernández, Jesús Avila

“…Neuroinflammation, a specialized immune response that takes place in the central nervous system, has been linked to neurodegenerative diseases, and specially, it has been considered as a hallmark of Alzheimer disease, the most common cause of dementia in the elderly nowadays. Furthermore, neuroinflammation has been demonstrated to affect important processes in the brain, such as the formation of new neurons, commonly known as adult neurogenesis. …”
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CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease by J. Thome, A. N. Coogan, A. G. Woods, C. C. Darie, F. Häßler

“…Presently, more and more data are emerging demonstrating how alterations of the CLOCK gene system might contribute to the pathophysiology of AD and other forms of dementia. At the same time, the impact of neuropsychiatric medication on CLOCK gene expression is under investigation.…”
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Positron emission tomography tracers for synucleinopathies by Jie Xiang, Zhentao Zhang, Shengxi Wu, Keqiang Ye

“…Abstract Synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, are characterized by the aggregation of α-synuclein. …”
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Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis by Junbin Liao, Junbin Liao, Wenfeng Cai, Danrong Lin, Yuanyun Xiao, Yanxi Liu, Yahui Wang, Yuquan Zhong, Fan Xiao, Heng Fang, Yilu Yao, Yunfeng Lin, Jiewen Su, Siyu Sun, Bo Zhang, Yan Wang, Wei Zhu, Wei Zhu

“…After adjusting for confounding factors, a higher DII was linked to a greater degree of disability, with the highest DII quartile showing a notably higher risk (OR = 2.61, 95% CI = 1.21–5.61) compared to the lowest quartile.ConclusionLack of exercise, previous exercise, stroke, and dementia are correlated with increased disability among older adults. …”
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Cognitive disorders in patients with atrial fibrillation by O.A. Yepanchintseva, A.S. Solonovych, O.S. Solonovych

“…AF is associated with an increased risk of dementia in patients with and without history of stroke. …”
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Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies by Shuguang Wang, Zuning Liao, Qiying Zhang, Xinyuan Han, Changqing Liu, Jin Wang

“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, accounting for approximately 70% of dementia cases worldwide. Patients gradually exhibit cognitive decline, such as memory loss, aphasia, and changes in personality and behavior. …”
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Inferior Frontal Gyrus Activation Underlies the Perception of Emotions, While Precuneus Activation Underlies the Feeling of Emotions during Music Listening by Ken-ichi Tabei

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Ensemble-Based Alzheimer's Disease Classification Using Features Extracted from Hog Descriptor and Pre-trained Models by Enver Akbacak, Nedim Muzoglu

“…Alzheimer's Disease is the most common type of dementia and is a progressive, neurodegenerative disease. …”
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Capgras syndrome, an interesting but rare phenomenon in Psychiatry: A case series by Arghya Halder, Sagarika Ray, Manish Kumar, Amit Kumar Bhattacharya

“…Although the phenomenon is known to occur as a part of other psychiatric disorders such as schizophrenia and mood disorders, it is not infrequently encountered in organic conditions such as cerebrovascular disease, dementia, and epilepsy. Thus, it is important to rule out any underlying organic etiology by the use of appropriate neuroimaging techniques whenever felt necessary. …”
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Treatment Tactics for Psychosis in Parkinson’s Disease: A Literature Review by Daiva Milmantienė

“…Pharmacological treatment may include antipsychotics (quetiapine, clozapine), dopamine D2 receptor antagonists, 5-HT2A receptor ligands, medications for dementia, anxiolytics, antidepressants, and gabapentin. …”
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Effectiveness of a specialist palliative home care nurse–patient consultation followed by an interprofessional telephone case conference compared with usual care among patients wit... by Judith Dams, Hans-Helmut König, Tim Friede, Nils Schneider, Stephanie Stiel, Martin Scherer, Silke Böttcher, Gabriella Marx, Ingmar Schäfer, Nadine Janis Pohontsch, Hendrik van den Bussche, Friedemann Nauck, Michael Freitag, Eva Hummers, Tina Mallon, Franziska Schade, Manuel Zimansky, Thomas Asendorf, Christiane A Mueller

“…Introduction Progressive chronic, non-malignant diseases (CNMD) like congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD) and dementia are of growing relevance in primary care. …”
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Sarcopenia is a risk factor for postoperative delirium in geriatric hip fracture patients: a retrospective study by Yi-Ming Qi, Hao-Tao Li, Shi-Min Chang, Sun-Jun Hu, Shou-Chao Du, Chen-Dong Liu, Yong-Qian Chu, Yun-Feng Rui, Yun-Feng Rui

“…Results of multivariate analysis identified sarcopenia (OR: 2.457, 95% CI 1.226–4.923, p = 0.011), ASA > 2 (OR: 3.968, 95% CI 1.805–8.722, p = 0.001), dementia (OR: 3.912, 95% CI 1.390–11.014, p = 0.010) and coronary heart disease (OR: 2.176, 95% CI 1.044–4.538, p = 0.038) as independent risk factors for POD in geriatric hip fracture patients.ConclusionThe incidences of POD and sarcopenia in geriatric hip fracture patients are high. …”
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Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment by Katharina Bolsewig, Eline A. J. Willemse, Pascual Sánchez-Juan, Alberto Rábano, Minerva Martínez, James D. Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ‘t Veld, Niklas Mattsson-Carlgren, Katerina Veverova, Christopher J. Fowler, Lynn Boonkamp, Marleen Koel-Simmelink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolande Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Lucilla Parnetti, Colin L. Masters, Alberto Lleó, Charlotte E. Teunissen, Marta Del Campo Milán

“…Here we evaluate plasma DDC, measured by proximity extension assay, and the effect of dopaminergic treatment in three independent LBD (with a focus on dementia with Lewy bodies (DLB) and Parkinson’s disease (PD)) cohorts: an autopsy-confirmed cohort (n = 71), a large multicenter, cross-dementia cohort (n = 1498) and a longitudinal cohort with detailed treatment information (n = 66, median follow-up time[IQR] = 4[4, 4] years). …”
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