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521
Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach
Published 2025-01-01“…Methods This pilot study proposes a serum investigation via nuclear magnetic resonance (NMR) spectroscopy in a consecutive series of AD patients including 57 patients affected by Alzheimer’s disease at dementia stage (AD-dem) and 45 patients with mild cognitive impairment (MCI) due to AD (MCI-AD). …”
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522
Investigating ITM2B‐associated ataxia in a Taiwanese cerebellar ataxia cohort
Published 2025-01-01“…Variations in the ITM2B gene, typically linked to dominantly inherited dementia, can sometimes present with cerebellar ataxia as an early symptom. …”
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523
Transdermal Physostigmine—Absence of Effect on Topographic Brain Mapping
Published 1993-01-01“…Nine patients with primary degenerative dementia (PDD) participated in an open trial of transdermal physostigmine (TPh). …”
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524
Inspired by struggle: A personal journey to global precision brain health
Published 2025-02-01“…He advocates for integrating diversity in neurodegeneration studies, crucial for understanding conditions like dementia. He founded ReDLat and BrainLat, advancing research across Latin America and empowering underrepresented voices. …”
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525
Frontostriatal Cognitive Staging in Parkinson's Disease
Published 2012-01-01“…Executive dysfunction and mental fatigue (stage I), depression/anxiety (stage IIa), apathy/pain (stage IIb), and dementia (stage III) reflect a sequential process of dopamine depletion occurring in different regions of the striatum (stages I and II) and the frontal cortex (stage III). …”
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526
Age-Related White Matter Changes
Published 2011-01-01“…Most recent studies have shown that WMC are associated with a host of poor outcomes, including cognitive impairment, dementia, urinary incontinence, gait disturbances, depression, and increased risk of stroke and death. …”
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527
Complete Renal Artery Embolization in a Comorbid Patient with an Arteriovenous Malformation
Published 2014-01-01“…We present a case of an elderly female who underwent a complete left renal artery embolization, following a difficult presentation complicated by advanced dementia and multiple comorbidities. This is the first documented case of complete renal artery embolisation used to treat a renal AVM.…”
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528
A Middle-Aged Woman with Logopenic Progressive Aphasia as a Precursor of Alzheimer's Disease: Case Report and Review of the Literature
Published 2011-01-01“…The logopenic variant is the least common one and is closely related to Alzheimer's disease in comparison to the other two variants that are closely related to frontotemporal dementia. We report the case of a middle-aged woman who presented to our center with progressive aphasia that was undiagnosed for two years. …”
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529
Correlation analysis between mild cognitive impairment and the traditional Chinese medicine body constitution types among the elderly in a community in Changning District, Shanghai
Published 2024-11-01“…The cognitive function was assessed by using the Clock Drawing Test combined with the Ascertain Dementia 8-item Questionnaire (AD8), the Montreal Cognitive Assessment (MoCA) and the Mini-mental State Examination (MMSE). …”
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530
Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment.
Published 2025-01-01“…<h4>Background</h4>To date, few data to transcranial Doppler sonography (TCD) are available in patients with mild vascular cognitive impairment (VCI) at risk for vascular or mixed dementia. In a previous study in patients with mild VCI and cerebral small vessels disease, a hemodynamic pattern of cerebral hypoperfusion and enhanced vascular resistance were observed; however, longitudinal data are currently lacking. …”
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531
Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives
Published 2025-05-01“…Objectives: Hearing loss is associated with increased cognitive decline and incident dementia in older adults. Given the rapidly rising incidence of dementia, management of modifiable risk factors such as hearing loss, is essential to mitigate the impact on the individual and society in general. …”
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532
Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease
Published 2015-01-01“…Recent research has provided evidence that insulin resistance and impaired insulin signalling may be a contributory factor to the progression of diabetes, dementia, and other neurological disorders. Alzheimer’s disease (AD) is the most common subtype of dementia. …”
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533
Why Are the Right and Left Hemisphere Conceptual Representations Different?
Published 2014-01-01“…The present survey develops a previous position paper, in which I suggested that the multimodal semantic impairment observed in advanced stages of semantic dementia is due to the joint disruption of pictorial and verbal representations, subtended by the right and left anterior temporal lobes, rather than to the loss of a unitary, amodal semantic system. …”
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534
Alzheimer’s Type Neuropathological Changes in a Patient with Depression and Anxiety: A Case Report and Literature Review of Neuropathological Correlates of Neuropsychiatric Symptom...
Published 2023-01-01“…Alzheimer’s disease (AD) is classified as a tauopathy and is the most common neuropathological correlate of dementia/cognitive impairment. AD is neuropathologically characterized by the presence of beta-amyloid immunoreactive senile plaques and tau positive neurofibrillary tangles. …”
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535
An Approach to Diagnostic Criteria for the Definition of Slight Cognitive Impairment
Published 2009-12-01“…For years the term slight cognitive impairment has been used in literature as a transitional stage between normal aging and a slight Alzheimer’s disease and in conversion studies it has been associated to quantitative and qualitative alterations that support that support the hypothesis that slight cognitive impairment constitutes an early stage of dementia in most of the patients. In this search the most updated diagnostic criteria on the topic have been reviewed looking for both a diagnostic consensus among the multiple and heterogeneous symptoms of this disorder and a clear, concise and uniform criterion that allow to reach a right definition and diagnosis of patients with slight cognitive impairment.…”
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536
The role of neurofilament light chain in the context of neurological disorders
Published 2020-12-01“…The purpose of this article is to review the literature on the role of NFL in the context of dementia, amyotrophic lateral sclerosis, HIV-associated neurocognitive disorders, multiple sclerosis, and other neurological diseases. …”
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537
Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases
Published 2013-01-01Get full text
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538
Consensus on rapid screening for prodromal Alzheimer’s disease in China
Published 2024-02-01“…Alzheimer’s disease (AD) is a common cause of dementia, characterised by cerebral amyloid-β deposition, pathological tau and neurodegeneration. …”
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539
A study on the exploration of mild cognitive impairment in Parkinson’s disease based on decision-making cognitive computing
Published 2025-01-01“…Mild cognitive impairment in Parkinson’s disease (PD-MCI) as an independent risk factor for dementia in Parkinson’s disease has prognostic value in predicting dementia in PD patients. …”
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540
Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Published 2025-01-01“…Abstract Cognitive impairment and dementia have long been recognized as growing public health threats. …”
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