Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment by Congcong Fang, Longqin Lv, Shanping Mao, Huimin Dong, Baohui Liu

“…On the basis of numerous studies, mild cognitive impairment (MCI) is a harbinger of dementia in PD, which is observed as an intermediate state with considerable variability; some patients remain stable and some even revert to normal cognition. …”
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Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a viciou... by Yin Jin, Apostolia Topaloudi, Sudhanshu Shekhar, Guangxin Chen, Alicia Nicole Scott, Bryce David Colon, Petros Drineas, Chris Rochet, Peristera Paschou

“…Abstract Dementia refers to an umbrella phenotype of many different underlying pathologies with Alzheimer’s disease (AD) being the most common type. …”
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The Effects of Light-to-Moderate Alcohol Consumption on the Cognitive Function of Community Nondemented Male Elderly: A Cohort Study by Zhang Yan, Zhang Yingjie, An Na, Qiu Qi, Li Wei, Wang Wenzheng, Sun Lin, Xiao Shifu

“…There was no difference in cognitive performance decline and new-onset dementia rates at follow-up. Conclusions. Light-to-moderate alcohol consumption had no significant impact on the overall cognitive function and the risk of dementia in elderly men.…”
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Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations by Dominica Hudasch, Franz Felix Konen, Nora Möhn, Lea Grote-Levi, Ulrich Wurster, Gabriel Welte, Josef Conzen, Nima Mahmoudi, Thomas Skripuletz, Philipp Schwenkenbecher

“…Clinical manifestations ranged from cognitive impairments resembling primary dementia to movement disorders mimicking Parkinson's disease, tremor, and epileptic seizures. …”
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Pediatric Interventions in a Sanfilippo Syndrome Patient Under General Anesthesia: A Case Report by Ahmad Al Malak, Hassan Issawi, Mohammad Hassoun, Mohammad Al Halabi

“…Case Presentation: A 9-year-9-month-old female was presented at our private clinic accompanied with her parents and referred from a general practitioner, and the preclinical examination revealed atypical craniofacial structure and skeletal features such as abnormal posture and movements adding on atypical behavioral manifestations such as temper tantrums, speech difficulties, dementia, and destructive behavior.…”
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Hippocampal connectivity dynamics and volumetric alterations predict cognitive status in migraine: A resting-state fMRI study by Seyda Cankaya, Behcet Ayyildiz, Dila Sayman, Umutcan Duran, Dogukan Ucak, Ramazan Karaca, Sevilay Ayyildiz, Ece Ozdemir Oktem, Hatice Lakadamyalı, Ceyhun Sayman, Ahmet Ozsimsek, Ali Yalçınkaya, Lutfu Hanoglu, Halil Aziz Velioglu, Burak Yulug

“…The etiology of cognitive decline linked to migraine remains unclear, with a growing recurrence rate and potential increased dementia risk among sufferers. Cognitive dysfunction has recently gained attention as a significant problem among migraine sufferers that can be related to alterations in hippocampal function and structure. …”
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The role of sleep in Alzheimer’s disease: a mini review by Jay Pathmanathan, M. Brandon Westover, Sudhir Sivakumaran, Jacob Donoghue, Corey B. Puryear

“…Understanding these relationships could lead to readily accessible and easily quantifiable biomarkers of Alzheimer’s dementia.…”
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Pathology of Synapses and Dendritic Spines by Shira Knafo, Gunnar K. Gouras, Xiao-Xin Yan, Tara Spires-Jones

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Upper and Lower Face and Ideomotor Apraxia in Patients with Alzheimer’s Disease by Jay Guido Capone, Sergio Della Sala, Hans Spinnler, Annalena Venneri

“…This study aimed at investigating the frequency of lower (mouth, tongue and throat) and upper (eyes and eyebrows) face apraxia, in AD and its relationship with limb apraxia and severity of dementia.…”
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Topographic Mapping of P300 and Frontal Cognitive Function in Parkinson’s Disease by Mutsumi Iijima, Mikio Osawa, Makoto Iwata, Akiko Miyazaki, Hideaki Tei

“…The purpose of this study was to evaluate the relationship between P300 that is one of the event-related potentials and frontal cognitive functions in Parkinson’s disease (PD) without clinically apparent dementia.…”
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A blood test for Alzheimer’s disease: a decade of progress and success by Nicholas J. Ashton, Henrik Zetterberg

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Cognitive Retardation in a Patient with Preservation of Psychomotor Speed by J. R. Willison, E. K. Warrington

“…He showed many similarities with patients previously described as having subcortical dementia. The selective preservation of psychomotor responding in the context of his gross bradyphrenia, however, was unexpected.…”
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A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults by Louis Bherer, Kirk I. Erickson, Teresa Liu-Ambrose

“…Results from cross-sectional, longitudinal, and intervention studies with healthy older adults, frail patients, and persons suffering from mild cognitive impairment and dementia are reviewed and discussed. Together these finding suggest that physical exercise is a promising nonpharmaceutical intervention to prevent age-related cognitive decline and neurodegenerative diseases.…”
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A qualitative study on the impact and participation in the AGELESS multidomain intervention: Insights from older adults with cognitive frailty and their caregivers by Ying Qian Ong, Suzana Shahar, A’isyah Mohd Safien, Norhayati Ibrahim, Ai-Vyrn Chin, Francesca Mangialasche, Miia Kivipelto, Devinder Kaur Ajit Singh

“…Abstract Background Cognitive frailty (CF) is a major precursor to dementia, and multidomain interventions have the potential to delay, prevent or reverse its early onset. …”
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UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases by Marco Capó, Silvia Vitali, Georgios Athanasiou, Nicole Cusimano, Daniel García, Garth Cruickshank, Bipin Patel

“…Additionally, these models show strong potential as biomarkers for neurodegenerative conditions, such as dementia, where brain age prediction achieved an AUROC of up to 0.90 in distinguishing healthy individuals from those with dementia.…”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…Abstract Background Early diagnosis is crucial to the optimal management of patients with cognitive impairment due to Alzheimer’s disease (AD) or AD-related dementias. For some patients, early detection of cognitive impairment enables access to disease-modifying therapies. …”
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A Meta-Analysis of GBA-Related Clinical Symptoms in Parkinson’s Disease by Yuan Zhang, Li Shu, Xun Zhou, Hongxu Pan, Qian Xu, Jifeng Guo, Beisha Tang, Qiying Sun

“…Besides, clinical features like family history, AAO, UPDRS-III, H-Y, and dementia previously analyzed were updated with new data added. …”
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Different rs-fMRI Data Processing Methods in the Study of Vascular Cognitive Impairment by Ying GUAN, Luwen ZHU, Feng WANG, Danna CAO, Xiaoling LI, Qiang TANG

“…Vascular cognitive impairment(VCI)refers to dementia associated with small vessel damage caused by long-term hypertension, diabetes, hyperlipidemia and other cerebrovascular risk factors. …”
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Association between retinal markers and cognition in older adults: a systematic review by Gerald Liew, Bamini Gopinath, Joyce Chan, Joyce Siette, Varshanie Jeevakumar, Rebekah Sefton, Tejal M Shah

“…Further longitudinal studies are required to validate our synthesis and understand underlying mechanisms before recommending implementation of OCT as a dementia screening tool in clinical practice.PROSPERO registration number CRD42020176757.…”
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The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review by Julia Lachowska, Karolina Senior, Jerzy Smandek, Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński

“… Dementia, particularly Alzheimer's disease (AD), is a growing global health concern, with an estimated 50 million people affected worldwide. …”
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