Real-World Outcomes of Pralsetinib in RET Fusion-Positive NSCLC by Francesca Lucibello, MD, Valérie Gounant, MD, PhD, Mihaela Aldea, MD, PhD, Michaël Duruisseaux, MD, PhD, Maurice Perol, MD, Christos Chouaid, MD, Jaafar Bennouna, MD, PhD, Vincent Fallet, MD, Aldo Renault, MD, Florian Guisier, MD, PhD, Etienne Giroux-Leprieur, MD, PhD, Marie Wislez, MD, PhD, Anne-Claire Toffart, MD, PhD, Julien Mazieres, MD, PhD, Clémence Basse, MD, PhD, Nadia Hegarat, PhD, Matthieu Carton, MD, Nicolas Girard, MD, PhD

“…Design: Retrospective study of consecutive patients enrolled in the French expanded-access program for pralsetinib from December 1, 2019, to December 31, 2021. Participants: A total of 41 patients with advanced, refractory, RET fusion-positive NSCLC were included. …”
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Analysis of the relationships between the degree of migraine with right-to-left shunts and changes in white matter lesions and brain structural volume by Xin Pan, Haoran Ren, Lili Xie, Yu Zou, Furong Li, Xiaowen Sui, Li Cui, Zhengping Cheng, Jiaojiao Wu, Feng Shi, Hongling Zhao, Shubei Ma

“…A total of 102 migraineurs with RLS admitted to the affiliated Central Hospital of Dalian University of Technology from December 2018 to December 2022 were enrolled in this study. …”
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Evaluation of Modified Frailty Index-5 as a Predictor of 60-day Perioperative Morbidity and Mortality in Geriatric Patients Presenting for Orthopaedic Surgery: A Prospective Cohort... by Aparna Ashay Nerurkar, Amreen Fatima

“…Materials and Methods: The prospective cohort study was conducted at Lokmanya Tilak Municipal General Hospital, Mumbai, Maharashtra, India, from December 2019 to December 2020. Details of participants and caregivers, mFI-5 scores and surgical details of 62 patients aged >65 years undergoing orthopaedic surgeries were studied. …”
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AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…MethodsThis retrospective study at Tri-Service General Hospital (September to December 2023) analyzed 746 ICU patients with suspected pneumonia-induced sepsis (supported by radiographic evidence and a SOFA score increase of ≥2 points), alongside 746 stable outpatients as controls. …”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Specifically, VICONEL allows for the monitoring of HIV treatment outcomes and health system performance, encompasses a biobank for further research with routinely collected blood plasma samples of consenting participants and provides a valuable framework for nested observational and interventional studies.Participants VICONEL captures routine viral load test results alongside associated demographic and treatment information among people in care for HIV in Lesotho, southern Africa. As of December 2023, it encompasses all viral load testing from 24 healthcare facilities in two districts of Lesotho.Findings to date From January 2016 to December 2023, 137 660 viral load test results were available for 29 380 participants. …”
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Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“…ResultsThe protocol was funded by the South African Medical Research Council following external peer reviews (December 2022). The study received initial ethics approval (May 2022), renewal (June 2023), and amendment (July 2024) from the University of Johannesburg (UJ) Research Ethics Committee. …”
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Derivation and validation of a prediction model for inadequate bowel preparation in Chinese outpatients by Huifang Yin, Yan Wang, Hangfang Wang, Tian Li, Xiangxiang Xu, Fengyu Li, Lihua Huang

“…A total of 1314 patients were included from December 15, 2022 through May 31, 2023 (derivation cohort, n = 1035) and from June 1 through August 12, 2023 (external validation cohort, n = 279). …”
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Does a complex intervention targeting communities, health facilities and district health managers increase the utilisation of community-based child health services? A before and af... by Joanna Schellenberg, Della Berhanu, Lars Åke Persson, Muluemebet Abera Wordofa, Araya Abrha Medhanyie, Fisseha Ashebir Gebregizabher, Habtamu Beyene, Ephrem Tekle Lemango, Abebe Bekele, Theodros Getachew, Mezgebu Yitayal, Yemisrach Behailu Okwaraji, Atkure Defar, Fitsum W/Gebriel, Alem Desta, Dawit Wolde Daka, Alemayehu Hunduma, Tigist Getahun, Amare Tariku Woldemariam, Desta Wolassa

“…We report the intervention’s effectiveness on care utilisation for common childhood illnesses.Methods We included a representative sample of 5773 households with 2874 under-five children at baseline (December 2016 to February 2017) and 10 788 households and 5639 under-five children at endline surveys (December 2018 to February 2019) in intervention and comparison areas. …”
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Effectiveness and Safety of the TRIO Optimal Health Management Program in Patients With Type 2 Diabetes Mellitus Initiating Basal Insulin Therapy: Prospective Observational Real-Wo... by Chenxi Li, Lixin Guo, Lixin Shi, Li Chen, Liming Chen, Yaoming Xue, Hong Li, Yuzhen Liang, Jing Yang, Weimin Wang, Dalong Zhu

“…ResultsA total of 199,431 patients were included, and 118,134 patients completed the 3-month follow-up between December 1, 2019, and December 31, 2021, involving 574 hospitals in China. …”
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Noel Hernández Rodríguez, scalpel in hand plastic surgeon by Tatiana Hernández González, Yaneisy Valdés Gutierrez, Yurisbel Tomás Solenzal Alvarez

“…Hilario Hernández Rodríguez, "Noe", as he was affectionately called by his residents and by all those who knew him as Noel, passed away on December 24, 2023, leaving an empty physical space next to family, friends, co-workers, patients and those who were his students for many years.…”
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Associations of dietary choline intake and kidney function with hyperuricemia in Chinese children and adolescents: a cross-sectional studyResearch in context by Chengping Li, Jing Li, Zhiquan Diao, Lianhong Chen, Siwen Yu, Lianlong Yu, Qianrang Zhu, Xiaomei Dong, Yiya Liu, Tao Liu, Dan Liu

“…The data for this study were collected from the China National Nutrition and Health Surveillance of Children and Lactating Mothers (2016–2017) conducted between October 2016 and December 2018. Eligible participants were identified through a database search conducted from October to December 2023. …”
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Different Clinical Features of Acral Abortive Hemangiomas by N. Vega Mata, J. C. López Gutiérrez, B. Vivanco Allende, M. S. Fernández García

“…We present five patients (three girls and two boys) with abortive hemangiomas diagnosed between January 2010 and December 2015 localized in acral part of the extremities. …”
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Interest Rate Pass‑through and Monetary Policy Transmission in SADC and EAC Countries: Implications for Monetary Union by Damilola Oyetade, Ephrem Habtemichael Redda, Paul‑Francois Muzindutsi

“…This study evaluates the potential for forming a monetary union using the panel autoregressive distributive lag model (PARDL) with monthly data from January 2000 to December 2022, including central bank and retail bank interest rates. …”
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The Environmentally IPM Package for Controlling Fall Armyworm (Spodoptera frugiperda) in Maize Field by Nova Yurina, My Syahrawati, Arneti Arneti, Munzir Busniah

“…This research was conducted in a farmer's maize plantation in the West Pasaman District from August to December 2021. The study used a Randomized Block Design (RBD) which consisted of three treatments and five replications. …”
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Evaluation of Finger Prints in Relation to Academic Performance of Students in Anatomy at Islam Medical and Dental College, Sialkot by Muhammad Junaid, Riaz Ahmad, Naureen Waseem, Aftab Ahmad, Aaqiba Rasheed, Rana Muhammad Zeeshan, Ayesha Riaz

“…The duration of the study was from mid-November 2022 to mid-December 2022. A total of 300 healthy medical (1st and 2nd year MBBS) and dental (1st year BDS) students with no injury and deformity, voluntarily participated in this study. …”
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Fish Health Management Considerations in Recirculating Aquaculture Systems - Part 1: Introduction and General Principles by Roy Yanong

“…Original publication date: December 2003. Cir 120/FA099: Fish Health Management Considerations in Recirculating Aquaculture Systems?…”
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Analysis of the Impact of Ride-Hailing on Urban Road Network Traffic by Using Vehicle Trajectory Data by Zijun Liang, Wei Kong, Xuejuan Zhan, Yun Xiao

“…This study matches data on the trajectories of different kinds of vehicles in Xuancheng city in the urban road network by using vehicle information data, ride-hailing information data, and license plate data recorded by the traffic bayonet system from December 26, 2018, to January 25, 2019. We used two indices, the detecting intensity and the detecting rate, to analyze the characteristics of travel based on ride-hailing services in Xuancheng. …”
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Correlation between Endometrial Vascular Endothelial Growth Factor Expression and Pregnancy Outcome of Frozen–Thawed Embryo Transfer in Patients with Repeated Implantation Failure... by Rui Jin, Wenye Ma, Dawei Tang, Fang Liu, Gang Bai, Mengmeng Reng

“…The Yinchuan Maternal and Child Health Hospital collected 192 cases of FET endometrial tissues in the implantation window stage between January 2019 and December 2021. Immunohistochemistry was utilized to measure the levels of VEGF expression in patients with RIF (RIF group, n=82) and patients with a successful pregnancy (control group, n=110). …”
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Universalization in the first course of Medicine studies: Experience during the first semester of 2004- 2005. by Margarita Roméu Escobar, Mayra Gil León, Raúl López Fernández

“…<strong>Methods:</strong> a qualitative and transversal section study developed from December 2004 to January 2005 in Cienfuegos province. …”
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Digital technology and human resource practices: A systematic literature review by Robson Mekonnin Shiferaw, Zerihun Ayenew Birbirsa

“…This research explores the relationship between digital technology and human resource practices, analyzing contemporary research conducted between 2016 and December 31, 2023. The systematic literature review adheres to fundamental review principles and identifies various studies conducted across various nations on the conceptual application of digital technology in human resource practices. …”
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