Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants by Guiqiang Wang, Kexin Zhao, Xiuli Zhao, Yimin Cui, Peng He, Tianzuo Zhang, Yanchao Wang, Rui Shi, Yanhua Li, Qian Wang, Yanping Ren, Zhisong Chen, Xuedan Zhao, Zekang Xie, Yufei Liang, Qingyun Tian, Jing Pan, Chao Zhang, Ying Han, Yuyang Dai, Siyang Ni, Yun Zhang, Xinjie Yang, Yongpan Fu, Dongfang Liu, Jing Li, Miaomiao Zhang, Zhongyu Hu, Liangzhi Xie

“…Background The development of bivalent or multivalent vaccines offers a promising strategy for combating SARS-CoV-2 mutations.Research design and methods In this phase 2 trial, conducted from 1 December 2021, to 25 July 2023, 392 unvaccinated adults aged ≥18 years were randomized to receive a primary series of two doses and a booster dose of SCTV01C, a bivalent protein SARS-CoV-2 vaccine.Results Geometric mean titers (GMTs) of neutralizing antibodies (nAb) against live Alpha, Beta, Delta, and Omicron showed 85.4-, 100.0-, 32.1-, and 9.8-fold increase from baseline on 28 days, and 49.4-, 55.3-, 5.7-fold increase against live Alpha, Beta, and Omicron on 90 days after primary series. …”
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Effect of Multi-Joint Functional Electrical Stimulation Combined with Conventional Rehabilitation Therapy on Lower Limb Motor Function of Patients with Stroke by LIU Jiapeng, WANG Weining, XU Dongyan, WANG Nianhong, WU Yi

“…ObjectiveTo investigate the effect of multi-joint functional electrical stimulation (FES) combined with conventional rehabilitation therapy on lower limb motor function of patients with stroke.MethodsA total of 35 patients with lower limb motor dysfunction after stroke were admitted to the Department of Rehabilitation Medicine in the Huashan Hospital, Fudan University from January to December 2023. The patients were randomly divided into control group and experimental group by SPSS 25.0 statistical software, with 16 and 19 cases in each group, respectively. …”
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Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Imran Khan, Stephanie J. C. Taylor, Clare Robinson, Elisavet Moschopoulou, Paul McCrone, Liam Bourke, Mohamed Thaha, Kamaldeep Bhui, Derek Rosario, Damien Ridge, Sheila Donovan, Ania Korszun, Paul Little, Adrienne Morgan, Olivier Quentin, Rebecca Roylance, Peter White, Trudie Chalder

“…Trial registration ISRCTN: ISRCTN67900293 . Registered on 09 December 2019. All items from the World Health Organization Trial Registration Data Set for this protocol can be found in Additional file 2 Table S1.…”
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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach by Zhangke Guo, Zhimin Li, Song Bai, Feng Tong, Jia Zheng, Nan Ding, Xiaofeng Li

“…Methods Between April 2022 and December 2023, 234 children with simple CHD who underwent CPB via a right-side small incision approach were separated into a control group (n = 93) without the use of a CO2 field-flooding device and a treatment group (n = 141) in which this device was added to the traditional surgical manual exhaust. …”
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Application of “One Syndrome and One Product” nursing model in nursing care of patients with optic atrophy (“一证一品”护理模式在青盲患者中的应用探讨) by LI Xianglu (李享璐), ZHANG Shuai (张帅), WANG Wei (王玮), WANG Qiao (王俏), HUANG Shaolan (黄少兰)

“…Methods Sixty patients diagnosed as optic atrophy (Qingmang) from July 2018 to December 2018 were included into the control group, and 60 patients diagnosed as optic atrophy (Qingmang) from January 2019 to June 2019 were recruited as study group. …”
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Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study by Zhongli Hu, Zinan Feng, Shiqi Liu, Hai He, Ying Dong, Zhiping Fan, Yiqing Li, Fen Huang, Na Xu, Can Liu, Yunxin Zeng, Ping Zhu, Ren Lin, Hua Jin, Xiong Zhang, Ruijuan Sun, Qifa Liu, Li Xuan

“…Results Between April 2009 and December 2019, 218 patients were included in this study, of whom 105 were in the intensified group and 113 were in the standard group. …”
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A phase II trial of anlotinib plus EGFR-TKIs in advanced non-small cell lung cancer with gradual, oligo, or potential progression after EGFR-TKIs treatment (CTONG-1803/ALTER-L001) by Hua-Jun Chen, Hai-Yan Tu, Yanping Hu, Yun Fan, Guowu Wu, Shundong Cang, Yi Yang, Nong Yang, Rui Ma, Gaowa Jin, Ximing Xu, Anwen Liu, Shubin Tang, Ying Cheng, Yan Yu, Chong-Rui Xu, Qing Zhou, Yi-Long Wu

“…Results From July 2019 to December 2022, 120 patients were enrolled. The median PFS (mPFS) was 9.1 months (95% CI 6.8–11.7). …”
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Endoscopic retrograde cholangiopancreatography combined with extracorporeal shock wave lithotripsy for the removal of large gallbladder stones: a pilot study by Liang Zhu, Jinli He, Zhenzhen Yang, Xi Huang, Junbo Hong, Xiaojiang Zhou, Youxiang Chen, Guohua Li

“…Methods In total, six patients (aged 23–72 years, 3 males and 3 females, Han ethnicity) who had large gallbladder stones (diameter ≥ 1 cm) complicated with common bile duct (CBD) stones and who underwent ERCP combined with ESWL at the First Affiliated Hospital of Nanchang University from July 2022 to December 2022 were enrolled. The patients’ clinical characteristics, endoscopic treatment and follow-up data were analyzed. …”
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Effect of narrative nursing combined with Traditional Chinese Medicine foot soaking and auricular acupoint pressing in the treatment of post-stroke sleep disorder (叙事护理联合中药泡足和耳穴贴压治... by CHAI Jingjing (柴晶晶), MENG Xiangnan (孟祥楠)

“…Methods From June 2022 to December 2022, 80 patients with sleep disorder after stroke admitted to the Rehabilitation Department of Beijing Longfu Hospital were selected and randomly divided into a control group and a study group, with 40 patients in each group. …”
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Profil Pasien Pneumonia Komunitas di Bagian Anak RSUP DR. M. Djamil Padang Sumatera Barat by Osharinanda Monita, Finny Fitry Yani, Yuniar Lestari

“…Djamil Hospital Padang in 2010–2012.This research was a descriptive study using medical records of children with primary diagnosis of CAP in the period of January 1, 2010 until December 31, 2012. During the study period, 178 patients were diagnosed as CAP, 55.6% found in boys, especially in the age group 2 - <12 months 43.8% with the poor nutritional status 62% and 34.8% have incomplete immunization status. …”
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Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trialResearch in context by Abha A. Gupta, Anna Tinker, Derek Jonker, Rahma Jamal, Hal Hirte, Eric W. Winquist, Quincy Chu, Christian Kollmannsberger, Ralph Wong, Thierry Alcindor, Torsten O. Nielsen, Ming Tsao, Tricia R. Cottrell, Diane Provencher, John Hilton, Monika K. Krzyżanowska, Christine Elser, Sebastien Hotte, Joana Sederias, Siwei Zhang, Wei Tu, Janet Dancey

“…This trial is registered with ClinicalTrials.gov, NCT02879162. Findings: From December 14th, 2016, to August 14, 2019, 140 patients enrolled into seven cohorts. …”
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A machine learning model to predict neurological deterioration after mild traumatic brain injury in older adults by Daisu Abe, Motoki Inaji, Takeshi Hase, Eiichi Suehiro, Naoto Shiomi, Hiroshi Yatsushige, Shin Hirota, Shu Hasegawa, Hiroshi Karibe, Akihiro Miyata, Kenya Kawakita, Kohei Haji, Hideo Aihara, Shoji Yokobori, Takeshi Maeda, Takahiro Onuki, Kotaro Oshio, Nobukazu Komoribayashi, Michiyasu Suzuki, Taketoshi Maehara

“…The model predictive accuracy was judged with the area under the receiver operating characteristic curve (AUROC) and the area under the precision-recall curve (AUPRC), and the Youden index was used to determine the cutoff value.ResultsA total of 421 of 721 patients registered in the Think FAST registry between December 2019 and May 2021 were included in our study, among whom 25 demonstrated neurological deterioration. …”
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Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration by Kathleen A. McGinnis, Amy C. Justice, Amy C. Justice, Vincent C. Marconi, Vincent C. Marconi, Maria C. Rodriguez-Barradas, Maria C. Rodriguez-Barradas, Ronald G. Hauser, Ronald G. Hauser, Krisann K. Oursler, Krisann K. Oursler, Sheldon T. Brown, Kendall J. Bryant, Janet P. Tate, Janet P. Tate, for the Veterans Aging Cohort Study

“…Patients were followed until December 31, 2021. We used Cox models to develop the VACS-CCI score and estimated mortality using a parametric (gamma) survival model. …”
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Sorafenib as Adjuvant Therapy Post–Liver Transplant: A Single-center Experience by Hala Hassanain, MD, Ashton A. Connor, MD, PhD, Elizabeth W. Brombosz, PhD, Khush Patel, MD, MS, Ahmed Elaileh, MD, Tamneet Basra, MD, Sudha Kodali, MD, MSPH, David W. Victor, III, MD, Caroline J. Simon, MD, Yee Lee Cheah, MD, Mark J. Hobeika, MD, Constance M. Mobley, MD, PhD, Ashish Saharia, MD, Sadhna Dhingra, MD, Mary Schwartz, MD, Anaum Maqsood, MD, Kirk Heyne, MD, Ahmed O. Kaseb, MD, Jean-Nicolas Vauthey, MD, A. Osama Gaber, MD, Maen Abdelrahim, MD, PhD, R. Mark Ghobrial, MD, PhD

“…Medical records of patients undergoing LT for HCC at a single center between January 2016 and December 2022 were retrospectively reviewed. Patients were stratified into 3 groups: (1) recipients of adjuvant sorafenib, (2) nonrecipients at high recurrence risk, and (3) nonrecipients at low risk by explant pathology features. …”
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Development of an accelerometer age- and sex-specific approach based on population-standardized values for physical activity surveillance: A proof of concept by Jairo H. Migueles, Cristina Cadenas-Sanchez, Nicole M. Butera, David R. Bassett, Dana L. Wolff-Hughes, Jennifer A. Schrack, Pedro F. Saint-Maurice, Eric J. Shiroma

“…Both approaches were compared for assessing adherence to PA guidelines and association of MVPA with all-cause mortality (ascertained through December 2015). Results: Both approaches indicated that 37% of the sample met the 150+ min/week guideline. …”
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Neoadjuvant chemoradiotherapy up-regulates PD-L1 in radioresistant colorectal cancer by Sung Uk Bae, Hye Won Lee, Jee Young Park, Incheol Seo, Jae-Min Cho, Jin Young Kim, Ju Yup Lee, Yoo Jin Lee, Seong Kyu Baek, Nam Kyu Kim, Sang Jun Byun, Shin Kim

“…Methods: Tissue specimens from preoperative biopsy via sigmoidoscopy and surgical resection were obtained from 24 patients with locally advanced rectal cancer (LARC) who underwent neoadjuvant chemoradiation therapy (CRT) between August 2016 and December 2017. Immunohistochemistry for PD-L1 in formalin-fixed paraffin-embedded tissue was performed from the endoscopic biopsy and surgical specimens. …”
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Recording dan Pencarian Silsilah Kambing Perah Menggunakan Algoritme Depth First Search by Rizki Wahyudi, Muhammad Iqbal, Lussy Dwi Oktaviana

“…The total number of active members of the Association is 186 Members and the total number of goats cultivated as of December 2018 is 2,214. Livestock data recording and pedigree recording of farm animals are the basis in livestock maintenance management, knowing that livestock records can determine proper maintenance management. …”
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The impact of urolithiasis on urology services in a high-prevalence region: A multicenter study by Wissam Khalid Kamal, Musab M. Alghamdi, Raed A. Azhar, Ahmad Bugis, Mohammed Abuzenada, Majed Alharthi, Saeed Bin Hamri, Yahya Ghazwani, Yasser A. Noureldin, Hassan Aljifri, Abdulaziz Alamri, Hatem Hamed Althubiany, Mansour Alnazari, Badr Alharbi, Abdulrahman Al Own, Mohanad Jebril Bosily, Mohammed Almansour, Abdullah Alfakhri, Ibrahim Alowidah, Ali Abdel Raheem

“…The analysis focused on the trends, distribution, and annual cost of endourological procedures for UUT urolithiasis from January 2017 to December 2022. Results: Out of the total surgery performed (54 711), over half (31 039, 57%) were related to UUT urolithiasis. …”
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Diplomacy and Recruitment of Mercenaries before the Battle of Žalgiris by Sven Ekdahl

“…In the meantime, in December 1409, Jagiello and Vytautas met at Brest-Litowsk in order to discuss and prepare a campaign against Prussia after the end of the armistice. …”
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Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy by SiQin Xiu, Li Tang, Chengjie Qin, Di Tian, Yuhong Chen, Lingling Gu, Liu Yang, Yuhao Sun, Xinghui Liu, Yonghong Lin, Yumei Wang

“…Methods We conducted a retrospective cohort study of 23,899 pregnant women who delivered between January 1, 2017 and December 31, 2019 at Chengdu Women’s and Children’s Central Hospital and West China Second Hospital of Sichuan University. …”
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