Co-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments by Ding B, Li M, Zhang J, Zhang X, Gao H, Gao J, Shen C, Zhou Y, Li F, Liu A

“…Baoyue Ding,1,2,* Mingjuan Li,2,* Jie Zhang,2,* Xiaojuan Zhang,2 Huan Gao,2 Jianqing Gao,3 Chunyan Shen,4 Yan Zhou,4 Fanzhu Li,5 Ailin Liu1 1Department of Pharmaceutical Analysis, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou, 350122, People’s Republic of China; 2Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, Jiaxing University College of Medicine, Jiaxing, Zhejiang, People’s Republic of China; 3Institute of Pharmaceutics, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058 People’s Republic of China; 4Jiaxing Institute for Food, Drug and Product Quality Control, Jiaxing, Zhejiang, People’s Republic of China; 5Zhejiang Chinese Medical University, School of Pharmaceutical Science, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fanzhu Li; Ailin Liu, Email lifanzhu@zcmu.edu.cn; ailinliu@mail.fjmu.edu.cnPurpose: The incidence of malignant melanoma (MM) has risen over the past three decades, and despite advancements in treatment, there is still a need to improve treatment modalities. …”
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S’approprier, c’est résister. Appropriations spatiales et mobilisation infra-politique des femmes en immobilité résidentielle et sociale dans les bidonvilles de Salé (Maroc)... by Myriame Ali-Oualla

“…Morocco’s shantytowns appeared in the first decades of the last century, bringing together people who had come from the countryside and the hinterland to meet the growing demand for labour in the imperial cities, which at that time represented the chief means of economic development. …”
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Effectiveness and Side Effect Incidence in a Real-World Digital Weight-Loss Service Using Compounded Semaglutide: A Retrospective Comparative Study by Louis Talay, Matt Vickers

“…However, research over the past decade has found them to be a safe and effective weight-loss agent, which has led to the approval of GLP-1 RAs such as Semaglutide as a supplement to lifestyle obesity interventions in multiple countries. …”
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Global, regional, national prevalence, mortality, and disability-adjusted life-years of cutaneous squamous cell carcinoma and trend analysis from 1990 to 2021 and prediction to 204... by Chengling Liu, Xingchen Liu, Pengjuan Cao, Xin Li, Haiming Xin, Sailin Zhu

“…By 2045, the global ASPR is projected to reach 64.66, with the ASMR and ASDR expected to decrease to 1.02 and 20.63 per 100,000, respectively.ConclusionOver the last three decades, the global burden of cSCC has increased significantly. …”
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Estimating Trends in Cardiovascular Disease Risk for the EXPOSE (Explaining Population Trends in Cardiovascular Risk: A Comparative Analysis of Health Transitions in South Africa a... by Shaun Scholes, Jennifer S Mindell, Mari Toomse-Smith, Annibale Cois, Kafui Adjaye-Gbewonyo

“…The absolute predicted 10-year risk of CVD declined significantly on average over the last 2 decades in both sexes (for linear trend; all P<.001). …”
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Defining “Giant” Mediastinal Tumors: Proposal of a New Clinical–Radiological Classification and Case Report by Emanuel Palade, George Bucur Delaca, Ioana-Medeea Titu, Sergiu Adrian Ciulic, Gabriel Cismaru, Adrian Stef, Simona Manole

“…<b>Methods</b>: A systematic review of the literature from the past decade was conducted using PubMed to identify relevant studies on “giant” mediastinal tumors. …”
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Providing an entrepreneurial marketing model based on teamwork with an emphasis on start-up companies by Parastoo Bafghi, Mahmoud Ahmadi Sharif, Sina Nematizadeh

“…The dimensions of the second level (networking and marketing public relations (C01)) act as interfaces.Extended Abstract                                           IntroductionThe last decade can be considered as the decade of attention to entrepreneurship and entrepreneurs in Iran. …”
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Designing a model for re-employment of employees during retirement (Study case: Ministry of Education) by Fatemeh Fatemeh Bina Baji, Hamid Rezaei Far, Mohammad Mohammadi, Monireh Salehnia

“…Considering the country's demographic changes and the effects and consequences of transitioning the age structure of the population, it is expected that the number of retirees in our society will continue to increase in the future decades (Statistical and Socioeconomic Analysis Office, 2019). …”
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A systematic scoping review of clinical indications for induction of labour. by Dominiek Coates, Angela Makris, Christine Catling, Amanda Henry, Vanessa Scarf, Nicole Watts, Deborah Fox, Purshaiyna Thirukumar, Vincent Wong, Hamish Russell, Caroline Homer

“…<h4>Background</h4>The proportion of women undergoing induction of labour (IOL) has risen in recent decades, with significant variation within countries and between hospitals. …”
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Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…Meanwhile, to meet high spectrum utilization, Non-Orthogonal Multiple Access (NOMA) has emerged as a potential technology in the last decade, for its ability to serve multi-user communication simultaneously by exploiting power-domain rather than time or frequency domains. …”
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Unraveling landslide failure mechanisms with seismic signal analysis for enhanced pre-survey understanding by J.-M. Chang, J.-M. Chang, C.-M. Yang, W.-A. Chao, W.-A. Chao, C.-S. Ku, M.-W. Huang, M.-W. Huang, T.-C. Hsieh, C.-Y. Hung

“…<p>Seismic signals, with their remote and continuous monitoring advantages, have been instrumental in unveiling various landslide characteristics and have been widely applied in the past decades. However, a few studies have extended these results to provide geologists with pre-survey information, thus enhancing the understanding of the landslide process. …”
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Dental and oral health assessments in the German National Cohort (NAKO) by Stefanie Samietz, Katrin Borof, Katrin Hertrampf, Ghazal Aarabi, Antonio Ciardo, Hannah Finke, Daniel Hagenfeld, Jan Kühnisch, Maurice Rütters, Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Ti-Sun Kim, Thomas Kocher, Wolfgang Ahrens, Hermann Brenner, Carina Emmel, Beate Fischer, Amand Führer, Karin Halina Greiser, Jasmin Grischke, Kathrin Günther, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Yvonne Kemmling, Alexander Kluttig, Lilian Krist, Oliver Kuss, Michael Leitzmann, Claudia Meinke-Franze, Karin B. Michels, Nadia Obi, Anette Peters, Nicole Pischon, Tobias Pischon, Sabine Schipf, Börge Schmidt, Henning Teismann, Stefan Rupf, Birte Holtfreter

“…Abstract Background Despite considerable improvements in oral health in recent decades, caries and periodontitis are still widespread, ranking among the most prevalent diseases worldwide and requiring future research. …”
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Climate change rivals fertilizer use in driving soil nitrous oxide emissions in the northern high latitudes: Insights from terrestrial biosphere models by Naiqing Pan, Hanqin Tian, Hao Shi, Shufen Pan, Josep G. Canadell, Jinfeng Chang, Philippe Ciais, Eric A. Davidson, Gustaf Hugelius, Akihiko Ito, Robert B. Jackson, Fortunat Joos, Sebastian Lienert, Dylan B. Millet, Stefan Olin, Prabir K. Patra, Rona L. Thompson, Nicolas Vuichard, Kelley C. Wells, Chris Wilson, Yongfa You, Sönke Zaehle

“…Over the entire study period, while N fertilizer application (42 ± 20 %) contributed the largest share to the increase in NHL soil emissions, climate change effect was comparable (37 ± 25 %), underscoring its significant role. In the recent decade (2007–2016), anthropogenic sources contributed 47 ± 17 % (279 ± 156 Gg N/yr) of the total N2O emissions from the NHL, while unmanaged soils contributed a comparable amount (290 ± 142 Gg N/yr). …”
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Marine sponge symbiotic bacterial bioremediation against heavy metal pollutants in tiger prawns; Penaeus monodon culture medium by I. Marzuki, I. Pratama, R. Asaf, A. Athirah, K. Nisaa, N. Nurbaya, M. Muslimin, N. Nurhidayah, S. Suwardi, A. Sahrijanna, K. Kamaruddin

“…BACKGROUND AND OBJECTIVES: The quality and production volume of the cultivation of tiger prawn Penaeus monodon have decreased considerably in the last two decades. However, intensification and extensification efforts, including the application of cultivation technology through pond land recovery, have not produced expected results. …”
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Mark loss can strongly bias estimates of demographic rates in multi-state models: a case study with simulated and empirical datasets by Touzalin, Frédéric, Petit, Eric J., Cam, Emmanuelle, Stagier, Claire, Teeling, Emma C., Puechmaille, Sébastien J.

“…The development of methods for individual identification in wild species and the refinement of Capture-Mark-Recapture (CMR) models over the past few decades have greatly improved the assessment of population demographic rates to address ecological and conservation questions. …”
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Prevalence and temporal trends in myopia and high myopia children in China: a systematic review and meta-analysis with projections from 2020 to 2050Research in context by Wei Pan, Seang-Mei Saw, Tien Yin Wong, Ian Morgan, Zhikuan Yang, Weizhong Lan

“…Summary: Background: Myopia rates have risen in the past decades in China. New strategies for the prevention and control of myopia are now available, and understanding the prevalence and future trends in myopia and high myopia in children and adolescents in China may provide insights into the impact of implementing these measures. …”
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Rewilding beech-dominated temperate forest ecosystems: effects on carbon stocks and biodiversity indicators by Markuljaková K, Mikoláš M, Svitok M, Meigs GW, Keeton WS, Kozák D, Pavlin J, Gloor R, Kalaš M, Ferenčík M, Ralhan D, Frankovič M, Hofmeister J, Dúhová D, Mejstrík M, Dušátko M, Veber A, Knír T, Svoboda M

“…We compared some of the best-preserved primary old-growth forests with adjacent secondary old-growth forests which have been allowed to undergo self-development for an extended period of seven decades in the ecologically and socially important beech-dominated forests of the Carpathian Mountains. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…The subjects were sorted into three groups based on residential addresses in loW-PM2.5, high-PM2.5, and traffic-related-air-pollution (TRAP)-PM2.5 areas on the basis of long-term PM2.5 pollution data from air monitoring sites collected over the past decade. Children living in the TRAP-PM2.5 areas had significantly higher TNF-α serum levels than those living in the I0W-PM2.5 areas. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Abstract Background Osteosarcoma is the most common malignant bone tumor in children and adolescents, characterized by high disability and mortality rates. Over the past three decades, therapeutic outcomes have plateaued, underscoring the critical need for innovative therapeutic targets. …”
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Crown structure indicates tree secondary growth, competition legacy, and growth potential of dominant species in Europe by Shamim Ahmed, Torben Hilmers, Enno Uhl, Frederico Tupinambá-Simões, Felipe Bravo, Miren del Río, Hans Pretzsch

“…The current crown structure was a reliable predictor of tree secondary growth over decadal scales. However, stronger relationships emerged when considering the entire tree ring series, suggesting a long-term morphological legacy effect of crown structure.These results show the importance of understanding how specific traits related to different tree species and their functional roles impact tree structure and growth. …”
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