Effect of Oral intake of Stevia Leaf Powder on Body Weight – An Experimental study by Amna Faruqi, Sikander Subuctageen, Irfan Afzal Mughal, Shahida Parveen, Tooba Zafar, Asma Irfan

“…This study was conducted to  find out the effect of Stevia leaf on body weight in obese Sprague Dawley male rats. Materials and Methods: This experimental study was carried out on 90 Sprague Dawley male rats. …”
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Effect Of Zinc And Ingredients Of Protein Supplement On Sperm Parameters And Male Reproductive Hormones- An RCT Study by Saira Safdar, Irfan Afzal Mughal, Noor Ul Ain, Sidra Jabeen, Muhammad Hassaan Farooq, Asma Irfan

“…Semen Analysis of Male Sprague Dawley rats of all 3 groups was evaluated after 8 weeks. …”
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Pharmacological Studies on the Antidiabetic, Antioxidant, and Antimicrobial Efficacies of Commiphora myrrha Resin in Streptozotocin-Induced Diabetes in Rats: A Preclinical Study by Rasha A. Mansouri, Aftab Ahmad, null Roushdy M. M., Huda F. Alshaibi, Mahmoud Ragab

“…The present study investigates the antioxidant, antimicrobial, and antidiabetic efficacies of aqueous extract of Commiphora myrrha resin (MAE) in streptozotocin-induced (STZ) diabetes in the female Sprague Dawley rats. Material and Methods. The thirty (30) female adult Sprague Dawley rats were randomly and equally segregated into three sets of experimental groups: group I (normal control): the rats were given an intraperitoneal injection of sodium citrate buffer solution and marked as a normal control group (NCG); group II (diabetic control): the rats were injected with STZ (60 mg/kg body weight (b.w.)) and marked as the diabetic control group (DCG); and group III (MAE treated): the rats were injected with STZ (60 mg/kg b.w.) for induction of diabetes and treated with MAE powder (0.5 mL of 0.5 g/kg b.w.) dissolved in distilled water. …”
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The effects of first mating age on average litter size at birth and weaning in rats by Ahmet Nazlıgül

“…Thirty female Sprague Dawley rats were used in this study. The ages of animais in the time of first mating were 10 weeks for the first group and 14 weeks for the second group. …”
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Livogrit mitigates ANIT-induced cholestasis-like symptoms in an in vivo model by curbing hepatic inflammation and regulating BAX, TGF-β, MMP-9 and α-SMA gene expression by Acharya Balkrishna, Ritu Paliwal, Surjeet Singh, Rani Singh, Vivek Gohel, Rishabh Dev, Kunal Bhattacharya, Sandeep Sinha, Anurag Varshney

“…Sprague-Dawley rats were pre-treated with Livogrit (20–600 mg/kg/day) and reference drug Ursodeoxycholic acid (100 mg/kg/day) for 15 and 5 days, respectively, before single-dose ANIT (100 mg/kg) stimulation. …”
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Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model by Sergio Li Calzi, Todd Cook, Domenico G. Della Rocca, Juan Zhang, Vinayak Shenoy, Yuanqing Yan, Andrew Espejo, Anandharajan Rathinasabapathy, Max H. Jacobsen, Tatiana Salazar, George E. Sandusky, Lynn C. Shaw, Keith March, Mohan K. Raizada, Carl J. Pepine, Michael J. Katovich, Maria B. Grant

“…Thy-1+/CD90+ cells were isolated from the bone marrow of adult Sprague-Dawley rats by immunomagnetic cell sorting. Six-week-old female Sprague-Dawley rats underwent permanent left anterior descending (LAD) coronary artery ligation and received intramyocardial injection of either saline, Isl-1+ cells, CD90+ cells, or a combination of Isl-1+ and CD90+ cells, at the time of infarction. …”
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Physicochemical properties and cytochromes P-450 kinetics of the trifluoroacetamido derivative of phenacetin by Hannah L. Cure, Thomas A. Shell

“…The kinetics of cytochromes P-450 (CYP) catalyzed oxidation of phenacetin and TFA-phenacetin were compared using Sprague Dawley (SD) rat liver microsomes. Phenacetin and TFA-phenacetin have the same apparent binding affinity for the SD rat liver microsome CYP proteome and undergo CYP catalyzed oxidation at the same rate in the presence of SD rat liver microsomes.…”
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Age-related Changes in p56lck Protein Levels and Phenotypic Distribution of T Lymphocytes in Young Rats by Heather J. Hosea, Edward S. Rector, Carla G. Taylor

“…The objective of this experiment was to determine changes in the levels of thymic and splenic T-cell p56lck using Western immunoblotting, along with the proportion and number of T-cell subsets in thymus, spleen and blood using flow cytometry in growing Sprague-Dawley rats. Thymic p56lck levels were negatively correlated with age (r=-0.42, p=0.04) and positively correlated with age in the spleen (r=0.50, p=0.01). …”
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A Toxicological Evaluation of a Standardized Hydrogenated Extract of Curcumin (CuroWhite™) by Alastimmanahalli Narasimhiah Ravikumar, Joby Jacob, Sreeraj Gopi, Tumkur Subbarao Jagannath

“…A 90-day repeated-dose study was conducted in male and female Sprague-Dawley rats. Two mortalities occurred in the main and satellite high-dose groups and were determined due to gavage error. …”
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Site of Nerve Division Affects Pain-Related Behavior and Spinal Cord Glial Proliferation after C7 Neurotomy in a Rat Stroke Model by Zhenpeng Li, Jintao Fang, Jiantao Yang, Bengang Qin, Wenting He, Jian Qi, Qingtang Zhu, Honggang Wang, Liqiang Gu

“…After middle cerebral artery occlusion (MCAO) was induced in male Sprague-Dawley rats, they underwent C7 neurotomy 0, 2, and 4 mm distal to the intervertebral foramen on the paralyzed side. …”
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Localisation of Lactate Transporters in Rat and Rabbit Placentae by Nigel P. Moore, Catherine A. Picut, Jeffrey H. Charlap

“…Groups of three pregnant Sprague-Dawley rats and New Zealand White rabbits were sacrificed on gestation days (GD) 11, 14, 18, or 20 and on GD 13, 18, or 28, respectively. …”
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The Effects of Aloe vera Cream on the Expression of CD4+ and CD8+ Lymphocytes in Skin Wound Healing by Yos Adi Prakoso, Kurniasih

“…Thirty-six male Sprague-Dawley rats weighing 150–200 grams were divided into four groups. …”
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Inflammation Modulating Activity of the Hydroethanol Stem Bark Extract of Bombax costatum in Murine Models by Meshack Antwi-Adjei, Kofi Oduro Yeboah, James Oppong-Kyekyeku, Newman Osafo

“…The effect of Bombax costatum extract (10, 50, 100 mg kg−1, p.o) was studied in prostaglandin E2-induced paw oedema in Sprague–Dawley rats (n = 5). Subsequently, the effect of the extract on clonidine and haloperidol-induced catalepsy was also investigated in ICR mice (n = 5). …”
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Influence of Gastrectomy on Cortical and Cancellous Bones in Rats by Jun Iwamoto, Yoshihiro Sato, Hideo Matsumoto

“…The aim of the present study was to examine the influence of gastrectomy (GX) on cortical and cancellous bones in rats. Twenty male Sprague-Dawley rats were randomized into the two groups of 10 animals each: a sham operation (control) group and a GX group. …”
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The absorption of oral morroniside in rats: In vivo, in situ and in vitro studies by Xiong Shan, Li Jinglai, Mu Yanling, Zhang Zhenqing

“…In the present study, the pharmacokinetics and bioavailability studies of morroniside were conducted on Sprague-Dawley (SD) rats. A rat in situ intestinal perfusion model was used to characterize the absorption of morroniside. …”
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Resolvin D1 Reduces the Immunoinflammatory Response of the Rat Eye following Uveitis by Rossi Settimio, Di Filippo Clara, Ferraraccio Franca, Simonelli Francesca, D'Amico Michele

“…This study investigated whether the administration of resolvin D1 to rats with endotoxininduced uveitis (EIU) ameliorates the immuno-inflammatory profile of the eye. 24 h after the administration of 200 μg LPS into the footpad of Sprague-Dawley rats, severe changes of the structure of the eye occurred concomitantly with a severe inflammatory and immune response. …”
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Human-Mimic Submuscular and Premuscular Irradiated Rat Model: Histologic Characteristics of the Capsule Tissue in Contact with the Breast Implant by Hyung Bae Kim, Se Young Han, Jin Sup Eom, Hyun Ho Han

“…This study consisted of experiments on 12 Sprague–Dawley rats that underwent implant reconstruction using ADM. …”
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Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA by Yos Adi Prakoso, Chylen Setiyo Rini, Roeswandono Wirjaatmadja

“…Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. …”
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Evaluation of the hypocholesterolemic efficacy of lyophilized nerium oleander distillate by Harun Kizilay, Ahmet Levent Bas, Nuray Yazihan

“…<p> <b>Materials and Methods:</b> Three equal groups of 30 male Sprague-Dawley rats were formed. No application was made for the control group. …”
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Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone by Vishvesh H. Shende, Simon McArthur, Glenda E. Gillies, Jolanta Opacka-Juffry

“…The long-term effects of antenatal dexamethasone treatment on brain remodelling in 3-month-old male Sprague Dawley rats whose mothers had been treated with dexamethasone were investigated in the present study. …”
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