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41
Glycogen homeostasis and mitochondrial DNA expression require motor neuron to muscle TGF-β/Activin signaling in Drosophila
Published 2025-01-01“…Instead, loss of Actβ reduces levels of nuclearly encoded genes required for mtDNA replication, transcription, and translation and mtDNA levels. …”
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42
Ensuring the Stability of the Genome: DNA Damage Checkpoints
Published 2001-01-01“…A key component of the DNA damage response is checkpoint signalling, which monitors the state of the genome prior to DNA replication (G1/S) and chromosome segregation (G2/M). …”
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43
SMC translocation is unaffected by an excess of nucleoid associated proteins in vivo
Published 2025-01-01“…Abstract Genome organization is important for DNA replication, gene expression, and chromosome segregation. …”
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44
The DNA Polymerase _-Primase Complex: Multiple Functions and Interactions
Published 2003-01-01“…Because of this peculiarity the major role of the DNA polymerase _-primase complex (pol-prim) is in the initiation of DNA replication at chromosomal origins and in the discontinuous synthesis of Okazaki fragments on the lagging strand of the replication fork. …”
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45
Gene Expression during Survival of Escherichia coli O157:H7 in Soil and Water
Published 2011-01-01“…Cells incubated in soil microcosms for 14 days expressed genes for antibiotic resistance, biosynthesis, DNA replication and modification, metabolism, phages, transposons, plasmids, pathogenesis and virulence, antibiotic resistance, ribosomal proteins, the stress response, transcription, translation, and transport and binding proteins at significantly higher levels than cells grown in Luria broth. …”
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46
The consistency of vitamin B12 in marketed microalgae powders
Published 2024-12-01“…Vitamin B12 is a water nutrient that plays a key role, in DNA replication and the production of red blood cells as well as maintaining proper neuron function in the body system. …”
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47
Mechanism of Gene Amplification via Yeast Autonomously Replicating Sequences
Published 2015-01-01“…These specific bindings at ORC promote repeated rounds of DNA replication leading to gene amplification.…”
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48
Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis
Published 2022-01-01“…The potential pathways that are associated with ZAP70 were found to have included adaptive immune response, response to oxidative stress, DNA replication, and lipid binding. This study provides a theoretical foundation for developing immunotherapy drugs for HNSC patients. …”
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49
Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
Published 2010-01-01“…One of these pathways supports DNA replication events by in a sense adopting the mantra that one must “make the best of a bad situation” and tolerating covalent modification to DNA through less accurate copying of the damaged region. …”
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50
High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein
Published 2022-01-01“…Minichromosome maintenance complex component 7 (MCM7) belongs to the minichromosome maintenance family that is necessary for the initiation of eukaryotic DNA replication. Overexpression of the MCM7 protein is linked to cellular proliferation and is accountable for critical malignancy in many cancers. …”
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51
The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements
Published 2024-12-01“…Error catastrophe can be overcome by the parallel gain of DNA replication and DNA repair mechanisms in both genomes. …”
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52
Spontaneous and environment induced genomic alterations in yeast model
Published 2025-02-01“…Given the high conservation of DNA replication and repair machinery across different organisms, the insights gained from studies on yeast offer valuable perspectives for understanding the delicate balance between genome plasticity and integrity in other species.…”
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53
The unconventional Xer recombination machinery of Streptococci/Lactococci.
Published 2007-07-01“…Homologous recombination between circular sister chromosomes during DNA replication in bacteria can generate chromosome dimers that must be resolved into monomers prior to cell division. …”
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54
Aflatoxin B1-Associated DNA Adducts Stall S Phase and Stimulate Rad51 foci in Saccharomyces cerevisiae
Published 2010-01-01“…We suggest RAD51 functions to facilitate DNA replication after replication fork stalling or collapse in AFB1-exposed cells.…”
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55
High-resolution mapping of cell cycle dynamics during steady-state T cell development and regeneration in vivo
Published 2025-01-01“…Here, we employed in vivo dual-nucleoside pulse labeling combined with the determination of DNA replication over time as well as fluorescent ubiquitination-based cell cycle indicator mice to establish a quantitative high-resolution map of cell cycle kinetics of thymocytes. …”
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56
Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study
Published 2014-01-01“…Unlike the gamma, 12C irradiation affects DNA replication as detected by S-phase delay in cell cycle analysis. …”
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57
Genome characterization through dichotomic classes: An analysis of the whole chromosome 1 of A. thaliana
Published 2012-11-01“…The present work confirms that the recent mathematical model of the genetic code is a new paradigm for understanding the management and the organization of genetic information and is an innovative tool for investigating informational aspects of error detection/correction mechanisms acting at the level of DNA replication.…”
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58
Transforming Soil Stability: A Review on Harnessing Plant Cell Compounds and Microbial Products for Modifying Cation Exchange Capacity
Published 2024-12-01“…., Mg required for DNA replication and Ca required for their growth and maintenance. …”
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59
Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy
Published 2022-01-01“…RBBP7 (retinoblastoma binding protein 7) serves as component of serval complexes that regulate chromatin metabolism and functions in affecting DNA replication and controlling cell proliferation. In this research, upregulation of RBBP7 was found to be associated with the higher infiltration of CD8 naïve T, iTreg, and neutrophil cells and the lower amounts of Th1, central memory T, NKT, CD8 T, and dendritic cells. …”
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60
A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules
Published 2024-09-01“…These mechanisms include disruption of cellular processes within the parasite, interference with DNA replication, and modulation of host immune responses. …”
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