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An Overview of DNA Repair in Amyotrophic Lateral Sclerosis
Published 2011-01-01“…Increasing evidence supports mitochondrial dysfunction and oxidative DNA damage in ALS motor neurons. Several DNA repair enzymes are activated following DNA damage to restore genome integrity, and impairments in DNA repair capabilities could contribute to motor neuron degeneration. …”
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Herpes Simplex Virus Latency: The DNA Repair-Centered Pathway
Published 2017-01-01“…Here I describe the basic features of the DNA repair-centered pathway and discuss some of the experimental evidence supporting it. …”
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D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming
Published 2025-02-01“…Oncometabolites jeopardize genome stability and DNA repair by affecting high-order chromatin structure.…”
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Two Sides of the Same Coin: TFIIH Complexes in Transcription and DNA Repair
Published 2010-01-01“…TFIIH has roles in both transcription initiation and DNA repair. During the last 15 years, several studies have been conducted to identify the composition of the TFIIH complex involved in DNA repair. …”
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COMPUTATIONAL SCREENING TO IDENTIFY GENES INVOLVED IN DNA REPAIR IN ARABIDOPSIS THALIANA
Published 2024-12-01Subjects: Get full text
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DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy
Published 2015-07-01Subjects: Get full text
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7
Mouse ZGRF1 helicase facilitates DNA repair and maintains efficient fertility
Published 2025-01-01Subjects: Get full text
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8
True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair
Published 2010-01-01“…Nucleotide excision repair (NER) is a major DNA repair pathway in eukaryotic cells. NER removes structurally diverse lesions such as pyrimidine dimers, arising upon UV irradiation or bulky chemical adducts, arising upon exposure to carcinogens and some chemotherapeutic drugs. …”
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Molecular Mechanisms of the Whole DNA Repair System: A Comparison of Bacterial and Eukaryotic Systems
Published 2010-01-01“…All organisms have developed a complex network of DNA repair mechanisms. A variety of different DNA repair pathways have been reported: direct reversal, base excision repair, nucleotide excision repair, mismatch repair, and recombination repair pathways. …”
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Lung Cancer Risk and Genetic Polymorphisms in DNA Repair Pathways: A Meta-Analysis
Published 2010-01-01“…Genetic variations in DNA repair genes are thought to modulate DNA repair capacity and are suggested to be related to lung cancer risk. …”
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H3K4 methylation regulates development, DNA repair, and virulence in Mucorales
Published 2024-03-01Get full text
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RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses
Published 2025-01-01“…Mechanistically, this phenotype is independent from RIF1’s role in DNA repair and class switch recombination, and reflects its ability to modulate the transcriptional status of a subset of BLIMP1 target genes. …”
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Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
Published 2025-01-01Subjects: Get full text
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Genetic variants of the XRCC3 DNA repair gene: risk implications in breast cancer among Iraqi patients
Published 2024-12-01Subjects: Get full text
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Diversity in mitotic DNA repair efficiencies between commercial inbred maize lines and native Central American purple landraces
Published 2022-10-01“…Conclusions Significant differences in DNA repair efficiency exist between inbred lines and landraces of maize and may be linked to allelic diversity in key genes for homologous recombination. …”
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Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls
Published 2010-01-01“…We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lung cancer disease and 40 healthy controls. …”
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The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage
Published 2024-12-01Subjects: Get full text
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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber
Published 2024-11-01Subjects: Get full text
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Context effects on repair of 5′‐overhang DNA double‐strand breaks induced by Cas12a in Arabidopsis
Published 2024-10-01Subjects: Get full text
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Increased Vitamin B12 Levels in Patients with Oral Cancer
Published 2023-04-01Subjects: “…dna repair…”
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