Showing 21 - 40 results of 185 for search '"DNA repair"', query time: 0.07s Refine Results
  1. 21

    Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls by Marco Peluso, Armelle Munnia, Sara Piro, Alessandra Armillis, Marcello Ceppi, Giuseppe Matullo, Riccardo Puntoni

    Published 2010-01-01
    “…We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lung cancer disease and 40 healthy controls. …”
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    Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations. by Shahrez Syed, Sarah Aloe, Jeanette H Sutherland, William K Holloman, Neal F Lue

    Published 2024-12-01
    “…TRF2 is an essential and conserved double-strand telomere binding protein that stabilizes chromosome ends by suppressing DNA damage response and aberrant DNA repair. Herein we investigated the mechanisms and functions of the Trf2 ortholog in the basidiomycete fungus Ustilago maydis, which manifests strong resemblances to metazoans with regards to the telomere and DNA repair machinery. …”
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    RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

    Published 2025-01-01
    “…Abstract RecQ helicases, highly conserved proteins with pivotal roles in DNA replication, DNA repair and homologous recombination, are crucial for maintaining genomic integrity. …”
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  17. 37

    Genome Stability Pathways in Head and Neck Cancers by Glenn Jenkins, Kenneth J. O'Byrne, Benedict Panizza, Derek J. Richard

    Published 2013-01-01
    “…Defective DNA repair generates chromosomal derangement that can cause subsequent alterations in gene expression, and is a hallmark of progression toward carcinoma. …”
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  18. 38

    Sirt3 Regulates Response to Oxidative Stress by Interacting with BER Proteins in Colorectal Cancer by J. Kabzinski, A. Walczak, I. Majsterek

    Published 2022-01-01
    “…One of the most important protection mechanisms is DNA repair systems, both nuclear and mitochondrial. …”
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  19. 39

    Hydrogen Peroxide-Induced DNA Damage and Repair through the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells by Mahara Valverde, Jonathan Lozano-Salgado, Paola Fortini, Maria Alexandra Rodriguez-Sastre, Emilio Rojas, Eugenia Dogliotti

    Published 2018-01-01
    “…In addition, hydrogen peroxide-induced DNA damage increased through adipocyte differentiation; DNA repair capacity also decreased. This study is the first follow-up report on DNA repair capacity during adipogenic differentiation. …”
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  20. 40

    Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics by Chelsea Jenkins, Jenny Kan, Maureen E. Hoatlin

    Published 2012-01-01
    “…The pathway contains an upstream multiprotein core complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer, and a downstream pathway that converges with a larger network of proteins with roles in homologous recombination and other DNA repair pathways. Selective killing of cancer cells with an intact FA pathway but deficient in certain other DNA repair pathways is an emerging approach to tailored cancer therapy. …”
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