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Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls
Published 2010-01-01“…We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lung cancer disease and 40 healthy controls. …”
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The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage
Published 2024-12-01Subjects: Get full text
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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber
Published 2024-11-01Subjects: Get full text
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Context effects on repair of 5′‐overhang DNA double‐strand breaks induced by Cas12a in Arabidopsis
Published 2024-10-01Subjects: Get full text
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Increased Vitamin B12 Levels in Patients with Oral Cancer
Published 2023-04-01Subjects: “…dna repair…”
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Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer
Published 2025-01-01Subjects: Get full text
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Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.
Published 2024-12-01“…TRF2 is an essential and conserved double-strand telomere binding protein that stabilizes chromosome ends by suppressing DNA damage response and aberrant DNA repair. Herein we investigated the mechanisms and functions of the Trf2 ortholog in the basidiomycete fungus Ustilago maydis, which manifests strong resemblances to metazoans with regards to the telomere and DNA repair machinery. …”
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SURVIVAL CURVE ANALYSIS FOR DROSOPHILA MELANOGASTER WITH D-GADD45 OVEREXPRESSION IN THE NERVOUS SYSTEM
Published 2015-01-01Subjects: Get full text
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Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i>
Published 2025-01-01Subjects: Get full text
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A more significant role for insertion sequences in large-scale rearrangements in bacterial genomes
Published 2025-01-01Subjects: Get full text
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Alterations in DNA Damage Repair Genes Before and After Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer
Published 2025-01-01Subjects: Get full text
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Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice
Published 2025-01-01Subjects: Get full text
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Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells
Published 2025-01-01Subjects: Get full text
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RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining
Published 2025-01-01“…Abstract RecQ helicases, highly conserved proteins with pivotal roles in DNA replication, DNA repair and homologous recombination, are crucial for maintaining genomic integrity. …”
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Genome Stability Pathways in Head and Neck Cancers
Published 2013-01-01“…Defective DNA repair generates chromosomal derangement that can cause subsequent alterations in gene expression, and is a hallmark of progression toward carcinoma. …”
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Sirt3 Regulates Response to Oxidative Stress by Interacting with BER Proteins in Colorectal Cancer
Published 2022-01-01“…One of the most important protection mechanisms is DNA repair systems, both nuclear and mitochondrial. …”
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Hydrogen Peroxide-Induced DNA Damage and Repair through the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells
Published 2018-01-01“…In addition, hydrogen peroxide-induced DNA damage increased through adipocyte differentiation; DNA repair capacity also decreased. This study is the first follow-up report on DNA repair capacity during adipogenic differentiation. …”
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Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics
Published 2012-01-01“…The pathway contains an upstream multiprotein core complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer, and a downstream pathway that converges with a larger network of proteins with roles in homologous recombination and other DNA repair pathways. Selective killing of cancer cells with an intact FA pathway but deficient in certain other DNA repair pathways is an emerging approach to tailored cancer therapy. …”
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