From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Bi... by Cíntia Marques, Alexandre Porcello, Marco Cerrano, Farid Hadjab, Michèle Chemali, Kelly Lourenço, Basste Hadjab, Wassim Raffoul, Lee Ann Applegate, Alexis E. Laurent

Subjects: Get full text

Transgenic plants as a model for studying еpigenetic regulation of gene expression by T. V. Marenkova, E. V. Deineko

Subjects: Get full text

Efficiency to Discovery Transgenic Loci in GM Rice Using Next Generation Sequencing Whole Genome Re-sequencing by Doori Park, Dongin Kim, Green Jang, Jongsung Lim, Yun-Ji Shin, Jina Kim, Mi-Seong Seo, Su-Hyun Park, Ju-Kon Kim, Tae-Ho Kwon, Ik-Young Choi

Subjects: “…next generation sequencing (NGS) T-DNA…”
Get full text

The Impact of Modifiable Risk Factors on the Endothelial Cell Methylome and Cardiovascular Disease Development by Hashum Sum, Alison C. Brewer

Subjects: Get full text

Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP by Song Guo, Song Guo, Qihao Pan, Qihao Pan, Baokang Chen, Baokang Chen, Yijuan Huang, Yijuan Huang, Si Li, Si Li, Chenyu Gou, Chenyu Gou, Yu Gao, Yu Gao

Subjects: Get full text

Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis by Hua Guo, Jinyang Gao, Liping Gong, Yanqing Wang

Subjects: Get full text

Detecção e isolamento de lentivírus caprino em células do cordão umbilical de cabras by Juscilânia Furtado Araújo, Alice Andrioli, Raymundo Rizaldo Pinheiro, Renato Mesquita Peixoto, Ana Lídia Madeira de Sousa, Ana Milena Cesar Lima, Cíntia Daudt, Gabriel Paula Amaral, Samara Cristina Rocha Souza, Maria Fátima da Silva Teixeira

Subjects: Get full text

vmrseq: probabilistic modeling of single-cell methylation heterogeneity by Ning Shen, Keegan Korthauer

Subjects: “…DNA methylation…”
Get full text

Revealing the heterogeneity of treatment resistance in less‐defined subtype diffuse large B cell lymphoma patients by integrating programmed cell death patterns and liquid biopsy by Wei Hua, Jie Liu, Yue Li, Hua Yin, Hao‐Rui Shen, Jia‐Zhu Wu, Yi‐Lin Kong, Bi‐Hui Pan, Jun‐Heng Liang, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu

Subjects: “…ctDNA…”
Get full text

Triplet Therapy with PD-1 Blockade, Histone Deacetylase Inhibitor, and DNA Methyltransferase Inhibitor Achieves Radiological Response in Refractory Double-Expressor Diffuse Large B-cell Lymphoma with 17p Deletion by Runhui Zheng, Xiaobo Chen, Chunyan Wang, Pengfei Qin, Huo Tan, Xiaodan Luo

“…We report a case with “double-expressor” DLBCL treated with a combined regimen which consisted of programmed cell death protein 1 (PD-1) inhibitor, DNA methyltransferase inhibitor (DNMTi), and histone deacetylase inhibitor (HDACi). …”
Get full text

HRAD30A, a Gene Encoding a Class Y Low-Fidelity Dna Polymerase Has a Low Complexity Region in Intron I Associated with Tissue-Specific Alternative Splicing by James E. Cleaver, Manish Thakur, Stas Volik, Colin Collins

Get full text

Association of hepatitis B virus DNA levels with efficacy and safety and the impact of antiviral therapy on prognosis in liver cancer patients receiving immune checkpoint inhibitors therapy: a systematic review and meta-analysis by Hongxia Cui, Su Li, Wu Lv, Jing Xiang

Subjects: Get full text

Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and Dissemination by Suzana Angelica Silva Lustosa, Luciano de Souza Viana, Renato José Affonso, Sandra Regina Morini Silva, Marcos Vinicius Araujo Denadai, Silvia Regina Caminada de Toledo, Indhira Dias Oliveira, Delcio Matos

Get full text

Development of a Copro-RPA-CRISPR/Cas12a assay to detect Echinococcus granulosus nucleic acids isolated from canine feces using NaOH-based DNA extraction method. by Guoqing Shao, Xiaowei Zhu, Ruiqi Hua, Yanxin Chen, Guangyou Yang

“…To improve field applicability, we integrated a simple and cost-effective NaOH-Based DNA extraction method. Clinical validation included testing DNA extracted from eighteen canine fecal samples, followed by comparison with quantitative PCR (qPCR) and two commercial enzyme-linked immunosorbent assay (ELISA) kits.…”
Get full text

Increased interferon I signaling, DNA damage response and evidence of T-cell exhaustion in a patient with combined interferonopathy (Aicardi-Goutières Syndrome, AGS) and cohesinopathy (Cornelia de Lange Syndrome, CdLS) by Sorina Boiu, Nikolaos Paschalidis, George Sentis, Theodora Manolakou, Andrianos Nezos, Manolis Gialitakis, Maria Grigoriou, Erato Atsali, Melpomeni Giorgi, Argirios Ntinopoulos, Clio Mavragani, Periklis Makrythanasis, Dimitrios T. Boumpas, Aggelos Banos

Subjects: Get full text

KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition by Deniz Gökbuget, Liana Goehring, Ryan M. Boileau, Kayla Lenshoek, Tony T. Huang, Robert Blelloch

“…The causal relationships between these features and DNA replication timing (RT), especially during cell fate changes, are largely unknown. …”
Get full text

Exploring the Relationship Between Growth Hormone Secretagogue Receptor (GHSR) Gene and Body Proportions in Bangkok Chickens: Insights from DNA Sequencing and Hin6I Enzyme-Restricted PCR-RFLP Analysis by Gayuh Syaikhullah, Rosa Tri Hertamawati, Muhammad Adhyatma

Get full text

Methylome profiling of cell-free DNA during the early life course in (un)complicated pregnancies using MeD-seq: Protocol for a cohort study embedded in the prospective Rotterdam periconception cohort. by Marjolein M van Vliet, Sam Schoenmakers, Ruben G Boers, Lotte E van der Meeren, Joost Gribnau, Régine P M Steegers-Theunissen

“…Maternal cell-free DNA (cfDNA) partly originates from the placenta and could enable the minimally invasive study of placental DNA methylation dynamics. …”
Get full text

腺病毒载体介导的大鼠DNA 多聚酶β重组体的构建及其在PC12 细胞中的表达 by 钟建辉

“…【目的】为探讨DNA多聚酶β在神经细胞损伤中的作用与机制，构建其重组腺病毒载体，并在PC12细胞中表达。【方法】RT-PCR获取大鼠DNA多聚酶β(POLβ)的编码序列，TA克隆测序，酶切POLβ基因并连入穿梭质粒pAdTrack-CMV，电转至含腺病毒pAdeasy骨架质粒的大肠杆菌BJ5183。…”
Get full text

STUDI PERBANDINGAN PEMAKAIAN PRIMER HBS1 DAN HBS2 DENGAN PRIMER P7 DAN P8 DALAM DETEKSI DNA VIRUS HEPATITIS B PADA PENDONOR DARAH by Supiana Dian Nurtjahyani, Mohammad Amin, Retno Handajan

Subjects: “…dna virus hepatitis b…”
Get full text